This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this site. Copyright 2009, The Johns Hopkins University and John McGready. All rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided “AS IS”; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as needed. Section B More Examples Hourly Wages Recall the regression relating hourly wages (U.S. $) to years of formal education for a random sample of 534 workers from 1985 Workers who differ by one year in education levels have wages that differ by $0.75/hour on average (95% CI: $0.60 to $0.90 per hour; higher wages associated with more years of education) 3 Hourly Wages What is the relationship between hourly wages and worker’s sex? (1 = female, 0 = male) 4 Hourly Wages What is the relationship between hourly wages and worker’s sex? (1 = female, 0 = male) Female workers earned an average of $2.11/hour less than male workers in 1985 (95% CI $1.26 to $2.97 less per hour) 5 Hourly Wages What is the relationship between hourly wages and, years of formal education and worker’s sex? (1 = female, 0 = male): MLR 6 Hourly Wages Adjusted relationships from the MLR Relationship between wages and sex adjusted for years of education - Female workers earned an average of $2.12/hour less than male workers with the same level of education in 1985 (95% CI $1.33 to $2.92 less per hour) Relationship between wages and years of education adjusted for sex (sex-adjusted relationship) - Workers of the same sex who differ by one year in education levels have wages that differ by $0.75/hr on average (95% CI: $0.60 to $0.90 per hour; higher wages associated with more years of education) 7 Recapping the Results So far we have results from three models Years of education Unadjusted Unadjusted Adjusted SLR1: x = years of education SLR2: x = sex MLR: x1 = years of education, x2 = sex 0.75 (0.60-0.90) Sex (1 = F) R2 0.15 0.75 (0.60-0.90) -2.11 (-2.97, -1.26) -2.12 (-2.91, -1.33) 0.04 0.19 8 Example 2: Hemoglobin SLR from Hb on Packed Cell Volume (PCV) The estimated mean difference in Hemoglobin levels for two groups of subjects who differ by 1% in PCV is 0.20 g/dL (95% CI 0.10 to 0.30 g/dL) subjects with greater PCV have greater Hb levels on average 9 Example 2: Hemoglobin SLR from Hb on age (years) The estimated mean difference in hemoglobin levels for two groups of subjects who differ by one year of age is 0.13 g/dL (95% CI 0.09 to 0.17 g/dL): older subjects have greater Hb levels on average 10 Hemoglobin What is the relationship between hemoglobin and patient PCV and age?: MLR 11 Hemoglobin Adjusted relationships from the MLR Relationship between Hb and PCV adjusted for age - The estimated mean difference in Hemoglobin levels for two groups of subjects of the same age who differ by 1% in PCV is 0.10 g/dL (95% CI 0.04 to 0.17 g/dL) subjects with greater PCV have greater Hb levels on average Relationship between Hb and age adjusted for PCV - The estimated mean difference in hemoglobin levels for two groups of subjects with the same PCV who differ by one year of age is 0.10 g/dL (95% CI 0.07 to 0.14 g/dL): older subjects have greater Hb levels on average 12 Recapping the Results So far we have results from three models PCV (%) Unadjusted Unadjusted Adjusted SLR1: x = PCV SLR2: x = age MLR: x1 = PCV, x2 = age 0.20 (0.10-0.30) Age (years) R2 0.51 0.10 (0.04-0.17) 0.13 (0.09, 0.017) 0.10 (0.07, 0.14) 0.75 0.84 13