Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 The Biological Bases of Behavior Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Communication in the Nervous System • Hardware: – Glia – structural support and insulation – Neurons – communication – Soma – cell body – Dendrites – receive – Axon – transmit away – Terminal buttons – secrete neurotransmitters – Synapse – junction where information is transmitted Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Animation of Neural Transmission • NIH Animation - Neural Transmission Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.1 Figure 3.1 Structure of the neuron. Neurons are the communication links of the nervous system. This diagram highlights the key parts of a neuron, including specialized receptor areas (dendrites), the cell body (soma), the axon fiber along which impulses are transmitted, and the terminal buttons, which release chemical messengers that carry signals to other neurons. Neurons vary considerably in size and shape and are usually densely interconnected. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Myelinization • Glial cells wrap themselves around axons and this increases the speed of neural conduction Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Myelinization & neurons Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 The Neural Impulse: The Action Potential • The Action Potential • All – or – none law Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.2. Figure 3.2. The neural impulse. The electrochemical properties of the neuron allow it to transmit signals. The electric charge of a neuron can be measured with a pair of electrodes connected to an oscilloscope, as Hodgkin and Huxley showed with a squid axon. Because of its exceptionally thick axons, the squid has frequently been used by scientists studying the neural impulse. (a) At rest, the neuron’s voltage hovers around –70 millivolts. (b) When stimulated, there is a brief jump in a neuron’s voltage, resulting in a spike on the oscilloscope recording of the neuron’s electrical activity. This change in voltage, called an action potential, travels along the axon like a spark traveling along a trail of gunpowder. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 The Synapse: Where Neurons Meet • Synaptic cleft • Presynaptic neuron – Synaptic vesicles – Neurotransmitters • Postsynaptic neuron – Receptor sites Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.3 Figure 3.3 The synapse. When a neural impulse reaches an axon’s terminal buttons, it triggers the release of chemical messengers called neurotransmitters. The neurotransmitter molecules diffuse across the synaptic cleft and bind to receptor sites on the postsynaptic neuron. A specific neurotransmitter can bind only to receptor sites that its molecular structure will fit into, much like a key must fit a lock. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.4 Figure 3.4 Overview of synaptic transmission. The main elements in synaptic transmission are summarized here, superimposed on a blowup of the synapse seen in Figure 3.3. The five key processes involved in communication at synapses are (1) synthesis and storage, (2) release, (3) binding, (4) inactivation or removal, and (5) reuptake of neurotransmitters. As you’ll see in this chapter and the remainder of the book, the effects of many phenomena—such as pain, drug use, and some diseases—can be explained in terms of how they alter one or more of these processes (usually at synapses releasing a specific neurotransmitter). Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Neurotransmitters: Chemical Couriers • • • • Neurotransmitters Work in a “lock and key” fashion Agonist – mimics neurotransmitter action Antagonist –blocks action of a neurotransmitter Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Organization of the Nervous System • Central nervous system (CNS) – brain and spinal cord • Peripheral nervous system – nerves that lie outside the central nervous system • Somatic nervous system – voluntary muscles and sensory receptors • Autonomic nervous system (ANS) – controls automatic, involuntary functions – Sympathetic – Go (fight-or-flight) – Parasympathetic – Stop Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.5 Figure 3.5 Organization of the human nervous system. This overview of the human nervous system shows the relationships of its various parts and systems. The brain is traditionally divided into three regions: the hindbrain, the midbrain, and the forebrain. The reticular formation runs through both the midbrain and the hindbrain on its way up and down the brainstem. These and other parts of the brain are discussed in detail later in the chapter. The peripheral nervous system is made up of the somatic nervous system, which controls voluntary muscles and sensory receptors, and the autonomic nervous system, which controls the involuntary activities of smooth muscles, blood vessels, and glands. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Brain Regions and Functions • Hindbrain – medulla, pons, and cerebellum • Midbrain – dopaminergic projections, reticular formation • Forebrain – thalamus, hypothalamus, limbic system, cerebrum, cerebral cortex Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 The Cerebrum: Two Hemispheres, Four Lobes • Cerebral Hemispheres – two specialized halves connected by the corpus collosum • Four Lobes: – Occipital – vision – Parietal – somatosensory – Temporal – auditory – Frontal – movement, executive control systems Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 View of the Brain Figure 3.14 The cerebral cortex in humans. The cerebral cortex consists of right and left halves, called cerebral hemispheres. This diagram provides a view of the right hemisphere. Each cerebral hemisphere is divided into four lobes (which are highlighted in the bottom inset): the occipital lobe, the parietal lobe, the temporal lobe, and the frontal lobe. Each lobe has areas that handle particular functions, such as visual processing. The functions of the prefrontal cortex are something of a mystery, but they appear to include working memory and relational reasoning. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Brain Overview Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 The Limbic System Saul Kassin, Psychology. Copyright © 1995 by Houghton Mifflin Company. Reprinted by permission. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.12 Figure 3.12 Electrical stimulation of the brain (ESB) in the rat. Olds and Milner (1954) were using an apparatus like that depicted here when they discovered selfstimulation centers, or “pleasure centers,” in the brain of a rat. In this setup, the wire delivering electrical stimulation is suspended from above so the rat can move freely about the box. When the rat presses the lever, it earns brief electrical stimulation that is sent to a specific spot in the rat’s brain where an electrode has been implanted. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.13 Figure 3.13 The cerebral hemispheres and the corpus callosum. In this drawing the cerebral hemispheres have been “pulled apart” to reveal the corpus callosum. This band of fibers is the communication bridge between the right and left halves of the human brain. Photo: Wadsworth collection. Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 2 Hemispheres /Corpus Callosum • Left hemisphere – verbal processing: language, speech, reading, writing • Right hemisphere – nonverbal processing: spatial, musical, visual recognition Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Hindbrain • • • • Medulla Pons Cerebellum BRAIN STRUCTURES AND FUNCTIONS Psychology: Themes and Variations, Sixth Edition, Briefer Version, Wayne Weiten Chapter 3 Figure 3.15 Alzheimer’ s Disease and Brain Atrophy