November 30, 2006 Dear Disease Investigator, Congratulations! You have been selected to serve your community as an Infectious Diseases Investigator for Larimer County, Colorado. Your community is relying on you to be prompt, accurate, thorough, cautious, and diligent in your investigation. A state of emergency has been declared in Fort Collins due to a recent explosion in mysterious food intoxications. There are numerous persons who are potentially at risk for possibly fatal infections. Please use your scientific disease detective skills to solve each mystery. It is of the utmost importance that you inform us of the results of your investigation as soon as possible, as each passing moment jeopardizes the very lives of defenseless citizens, especially the very young, old, and unwell among us. Please identify each of the six food intoxications. Notify us immediately of your diagnosis and recommendations for treatment. Clearly, rapid diagnosis would be extremely helpful in developing policy and implementation of a plan to contain and minimize the incidence of infection in the general population of Fort Collins and the surrounding area. We anxiously await your learned and astute advice concerning strategies for avoiding further spread or future outbreaks of each of the diseases. Sincerely, Louis Pasteur, MD, PhD Larimer County Department of Health and Environment Bureau of Investigation Infectious Disease Division