HUMAN AND SOCIAL BIOLOGY GCE Ordinary Level Paper 5096/01 Theory General comments The paper generated a wide range of marks. Very few candidates failed to answer 3 questions in Section B and fewer than usual answered all 5, so examination technique is improving. In Section A, genetics proved once again to be a problem area, as did the calculations and the diagram-completion question. In Section B, weaker candidates seemed to select their questions on the basis of their first sections, so that they were often unable to answer later and more challenging sections when they reached them. It is always a good idea to read the whole text before starting a question. Further, when a question asks for two examples, giving a list of four or five possible answers will not increase the chances of scoring, since only the first two are marked. Comments on specific questions Section A Question 1 This question required five organisms to be identified from a list of six, using a key. Although the question used features commonly attributed to these organisms in the syllabus, the use of the key format caused problems for many. Keys are a useful way of testing the application of knowledge and could, perhaps, be practised more, so that this format is more familiar to the candidates. The answers were A-virus, Bbacterium, C-protozoan, D-hookworm and E-bloodfluke. Hookworm was identified correctly most often in this list. Question 2 This question dealt with methods by which materials move in and out of cells. (a) The answers were osmosis, active transport, phagocytosis and diffusion. Phagocytosis was usually recognised correctly from the description given, but diffusion and active transport were often confused. (b) The methods not requiring energy were osmosis and diffusion. Question 3 This question was generally well done, with most candidates able to name the liver and the pancreas. A good proportion could also identify bile and lipase as the two solutions. Naming two fat-soluble vitamins proved more difficult and many resorted to guesses here. Suitable answers were A, D, E or K. Question 4 (a) This part required the completion of a diagram of a spinal reflex arc by drawing in the sensory and motor neurones. This was poorly done by the majority, although the basic diagram is well known. The sensory neurone should run from the receptor into the spinal nerve, up the dorsal root and synapse to the relay neurone shown there. The cell body should be shown in the dorsal root ganglion. The motor neurone runs from its cell body down the ventral root and spinal nerve to the muscle. (b) Most candidates could name the relay or intermediate neurone. http://www.xtremepapers.net 1 (c) Few candidates could state that the transmission across the synapse was chemical. (d) Most candidates knew at least one effect of alcohol on the behaviour of an individual. Question 5 (a) This part proved difficult for many candidates, since they failed to read the question stem and appreciate that the clear areas represented no bacteria present. The largest effect was seen with B, the disinfectant. (b) This is toxic or would damage body tissues, so could not be used internally. (c) It was clear from the answers that the concept of a control in biological experiments is not appreciated. It is simply a repeat of the original experiment with one factor changed to see if there is any difference in the result. A suitable control here would be to repeat the experiment but substitute plain discs or discs with water to show it is the chemicals which produce the effect and not the paper discs alone. (d) Most candidates could identify penicillin as an antibiotic. Question 6 This question concerned the inheritance of eye colour. (a) P is Bb, since although brown eyed she has a blue eyed son T. V is also Bb, since his father is blue eyed and so contributes a recessive allele b to V, yet V is brown eyed. (b) Only S could be homozygous, he is brown eyed and with only one child U (who is also brown eyed) there is not enough evidence to say he is not BB. Question 7 Parts (a) and (b) required some calculations to be made using figures from the table. (a) The difference in carbon dioxide concentrations is 100 times. (0.04 v 4.0). (b) The oxygen-extraction efficiency is 20%; 4/20 x 100=20%. Question 8 This question produced some good scores. This is an area that is well understood by most candidates. The virus causing AIDS is HIV. Haemophiliacs need transfusions of blood or factor 8. If these transfusions come from infected sources the recipient may get AIDS, so infected blood transfusions was the answer. The body cell affected is the lymphocyte or T-helper lymphocyte or even the white blood cell, but not phagocyte. Section B Question 9 This question was a popular choice. Many scored well on part (a), stating how plants used carbon dioxide. Some confusions with respiration occurred, predictably. Calcium is needed for clotting and muscle contraction as well as for hardening bones and teeth. The hepatic portal vein was often identified correctly as the vessel carrying food to the liver. The fates of glucose and amino acids in the liver produced mixed quality answers. Glucose was the better understood, but the usual confusions between glucagon and glycogen spoiled some responses. Many answers referred correctly to amino acids being deaminated, but failed to score more by not saying what happened next: the ammonia is converted to urea; the fatty acid residue is respired or stored as glycogen or fat. Amino acids cannot be stored but may be built into proteins in the liver or changed into other amino acids. 2 Question 10 This question was less popular. In part (b), candidates often only made one point, when 3 marks were available. The bloods are kept separate because not only are their oxygen levels very different as most candidates said, but so too are their carbon dioxide levels and their pressures. Each of these differences could be related to the different circulations they serve. Thus, the high pressure of the left ventricle would burst the lung capillaries; the lower pressure of the right would be insufficient to supply the body circulation. Blood pressure is high at the glomerulus to promote filtration; to force small molecules into the capsule. If not filtration would slow up, so that solutes would stay in the blood as would water, leading to oedema. In part (d), the pacemaker is found in the wall of the right atrium. Its role is to initiate contraction waves in the muscle of the two atria, and then to stimulate the ventricular muscle. One group treated this as an artificial pacemaker installed in a failing heart. The effects of carbon monoxide on red blood cells were not well understood. Carbon monoxide has a very high affinity for haemoglobin, so combines more readily than oxygen; the reaction is irreversible and so reduces the amount of oxygen the blood can carry. Such damaged cells are removed from the blood leading to a lower red cell count. Question 11 This question, on the skeleton, was popular but carried a sting in its tail with 6 marks offered for a description of how muscles move food. (a)(b) These parts were usually well done. (c) The roles of the cartilages were usually overlooked, as were the close fit of the bone ends. Most limited themselves to a mention of synovial fluid and lubrication. Bone is living since it respires, grows and is composed partly of cells. This is advantageous since it grows as we grow, can repair itself and is a dynamic system responding to stresses as we exercise particular muscle-groups regularly. (d) The last section was the worst done, as a rule, with many contenting themselves with a brief reference to peristalsis. The description should have included references to contractions of the circular muscle(behind the bolus); relaxation of the circular muscle(in front of the bolus); contractions of the longitudinal muscle in antagonistic fashion; that these actions were rhythmic; the muscles acting against the gut contents. Question 12 This question attracted a lot of answers but, in fact, required fairly detailed knowledge of the life cycle of the mosquito, linked to feeding and to large-scale control methods of each stage. Confusion over the stages was often evident from the start. (a) The egg is supplied with food in the yolk. The larva feeds on algaeplanktonbacteria; in water; collecting these by its mouth-brushes, a form of filter-feeding. The pupa uses food stored inside its case. The adult male feeds on plant juices sucked from the leaf-veins. The female supplements her diet with blood before laying each batch of eggs using saliva as an anticoagulent. (b) This part asked for a large-scale method to control each stage, so references to emptying cans or flower-vases of their water were not allowed, nor were nets or coils to control the adult. The question asked for an explanation of each method chosen. This was frequently overlooked and it was not always clear to which stage the method referred. Thus B, thuringiensis is an excellent method for larvae but not for pupae. For adults insecticides, especially residual insecticides sprayed inside houses to kill them as they settle prior to feeding would score well, whereas the single word insecticide scores nothing. (c) Most candidates got 2 signs at least, but there was the usual confusion with symptoms. Feeling hot is a symptom, not a sign. Few mentioned the fact that the signs occur at regular intervals. (d) The net is to prevent the mosquito from becoming infected by biting the patient, as the majority of the answers suggested. 3 Question 13 This question was often chosen, probably for its easy opening section but, as with Question 11, more difficult sections awaited the unwary. (a) This part was usually answered well, although some failed to state how their pollutants affected the environment. (b) Most answers to this section lacked detail as to what was filtered and how this was achieved. Sedimentation and filtration were often confused. Further treatment is required, since the water may still contain bacteria, some of which may be pathogenic. Most suggested boiling or chlorination correctly as suitable methods but quite a lot thought fluoridation applied here too. (c) This part, on the uses of water, was the weakest section for all but a few candidates. Most talked of water only as a transport medium and listed all the substances it carried or referred to washing food or clothes when the question said the uses of water in the body. Water is also a reagent (in hydrolysis reactions); a component of cytoplasm and thus of cells and tissues. It is a large part of blood, lymph and tissue fluid as well as such liquids as tears, synovial fluid, semen, mucus etc. It distributes heat around the body and acts as a coolant when it evaporates as sweat. Paper 5096/02 Multiple Choice Question Number Key Question Number Key 1 C 21 D 2 D 22 D 3 D 23 D 4 A 24 B 5 C 25 C 6 D 26 B 7 B 27 C 8 D 28 D 9 A 29 A 10 B 30 B 11 B 31 D 12 B 32 C 13 C 33 D 14 B 34 C 15 C 35 D 16 C 36 D 17 D 37 B 18 D 38 D 19 C 39 A 20 A 40 A 4 General comments A standard deviation of 5.505 was obtained for this paper. The mean score was 17.096 (42.7%) which is lower than last year. However, with the low entry number of candidates this year, some caution is needed in interpreting the statistics. In particular, the low point biserial shown by Questions 6, 12, 29, 34 and 38 is somewhat unusual because these questions directly test only knowledge of one stated syllabus objective. Where understanding two syllabus objectives for the same question was needed, difficulty was encountered in applying the knowledge as shown by Questions 13, 16 and 20. The hygiene and health questions were most competently answered as shown by Questions 7, 8, 9, 25, 31 and 33. Questions 7, 9, and 33 appeared too easy, but it is pleasing that such relevant socially significant topics are well understood. Comments on specific questions Question 3 The positive distractor but good discrimination, indicates that the less able candidates thought lymphocytes are a tissue. See also Question 12, where it appears that study of the parts of the blood needs to be more thorough. Question 6 The syllabus objective which states, ‘proteins: used for growth and repair and as a component of haemoglobin’, was directly tested. Most candidates, instead of selecting haemoglobin, answered that proteins are needed to act as an energy store. While protein may act as an energy store, it is not needed for that purpose. Question 7 This was surprisingly well answered considering that a fairly complex table had to be interpreted to deduce which nutrients would keep bones and teeth healthy. Question 12 Candidates have to know that the fluid part of blood is plasma and that it transports carbon dioxide. This is directly from syllabus objective 5(c), so the low facility and point biserial are difficult to explain. Perhaps fluid was not considered to be plasma. Question 13 Most unusually, the fewest candidates chose the correct answer. The part played by muscle contraction in returning blood to the heart must have been neglected. This is essential knowledge to understand the syllabus section on circulation and how veins function. Question 15 The lack of understanding of how the pressure changes in the lungs during breathing is evident again here, as it has also been shown in previous years’ papers. The balloon and bell jar experiment is recommended to help teach this important concept. Question 16 The question combines syllabus section 1(k), diffusion, with 6(e), gaseous exchange in the alveoli. The need to invest knowledge with understanding is important, particularly when the transfer of knowledge between sections, studied at different times, is necessary. Question 17 The positive distractor was most likely caused by the inability to read the graphs. The distractor option A shows fewer babies with a low birth mass born to mothers who smoke during pregnancy, while the key response D shows more births with low mass. 5 Question 20 Again, the fewest candidates chose the correct answer. In this case, identifying the kidney cortex from a photomicrograph, or the lack of knowledge where filtration takes place, caused the difficulty. Question 35 The high positive distractor indicates that candidates are not clear about the difference between active and passive immunity, particularly in relation to breast milk. Question 38 It appears that this syllabus section may have been neglected, possibly because the syllabus provides an option to study either the trickle filter or the aeration tank method. Both were given in this question, but the answers showed a very poor understanding of where aerobic bacteria are active. 6