www.studyguide.pk NOVEMBER 2001 GCE ADVANCED SUBSIDIARY LEVEL MARK SCHEME MAXIMUM MARK : 50 SYLLABUS/COMPONENT : 8700/2 BIOLOGY (STRUCTURED QUESTIONS) http://www.xtremepapers.net www.studyguide.pk Page 1 of 3 1 Mark Scheme AS Level Examinations – November 2001 Syllabus 8700 (a) xylem vessel, transport of, water / ions; 1 (b) no cross walls; wide lumen / AW; strengthened / lignified / thick cell wall; no, cytoplasm / cell contents / organelles / hollow / empty; pits; 3 max (c) companion cell; movement of sucrose / other named substance; into / out of, sieve tubes / loading / unloading; through plasmodesmata; provides energy; active transport; 3 max [Total: 2 Paper 2 7] (a) elastin / elastic fibres; 1 (b) no recoil / alveoli do not recoil; (A) contract air not forced out; air not refreshed in alveoli; concentration of oxygen, falls / not maintained; less oxygen diffuses into the blood; 3 max (c) epidemiological evidence increase in cigarette smoking, increase in cases / deaths from lung cancer ~ 20 years later; more men than women smoked in the past, linked to greater number of cases / deaths among men; (A) anything similar to this lung cancer rare / unknown, before cigarette smoking became common; most people with lung cancer, smoke / have smoked; lung cancer very rare in non-smokers; lower incidence in smokers who do not inhale; (e.g. pipe and cigar smokers) ref to national differences in smoking and cancer / ref to developing countries; ref to studies involving British doctors; ref to evidence from passive smoking; AVP; 2 max experimental evidence experimental animals develop tumours similar to human lung tumours; carcinogens have been isolated from tar; when painted on animal skin induce tumours; [Total: 1 max 7] www.studyguide.pk Page 2 of 3 3 (a) Syllabus 8700 amino acid; 1 (ii) lose its shape / disrupted / uncoils / becomes straight chain; denature; hydrogen bonds break; 2 max disulphide / sulphur bridges; van der Waals / A/W; hydrogen ; ionic; 3 max may be branched; glycosidic links; no R groups; repeating unit structure / one monomer; AVP; 2 max three polypeptides twisted around each other; hydrogen bonds between polypeptides; covalent links between chains; every third amino acid glycine, small so tight coil; lay parallel to form fibrils; ends staggered / fibrils overlap, so strong; 2 max many –OH groups; hydrogen bonds within the molecule; hydrogen bonds between molecules; straight chain (not helix) / unbranched / linear; 60-70 chains / associated to form microfibrils; arranged in bundles to form, macrofibrils / fibres; 2 max (c) (i) (ii) [Total: 4 (a) (b) Paper 2 (i) (b) (d) Mark Scheme AS Level Examinations – November 2001 12] (i) serine; 1 (ii) UAG; 1 (iii) codon; 1 (iv) phenylalanine, not isoleucine as next amino acid; 1 secondary structure / alpha helix / pleated sheet; further folding / tertiary structure; ref named bond(s); transported in ER; Golgi; packaged / sugars added / trimmed; vesicles; exocytosis; 4 max [Total: 8] www.studyguide.pk Page 3 of 3 5 (a) (b) (c) Mark Scheme AS Level Examinations – November 2001 A B C D Syllabus 8700 nucleus; mitochondrion; phagosome / vacuole; lysosome; half mark each 2 lower resolution in light microscope; ref wavelength of light; maximum is half wavelength; 200 nm; many organelles / named example, smaller than this; 3 max attachment to cell membrane; receptors; role of antibodies / opsonins; folding inwards of cell membrane / endocytosis; formation of vacuole / phagosome; lysosomes fuse with vacuole; toxins kill bacteria; enzymes digest bacteria; 4 max [Total: 6 (a) Paper 2 statement causative organism is a bacterium causative organism is water-borne transmitted by an insect vector sexually transmitted cholera malaria HIV/AIDS TB ü û û ü ü û û û û ü û û û û ü û 9] one mark per row 4 (b) people who are heterozygous / carriers; resistant to malaria; children of heterozygotes; 1 in 4 chance of inheriting sickle cell anaemia; further detail of inheritance (e.g. Punnet square); only attacks HbAHbA / healthy R.B.Cs; 3 max [Total: 7] Total mark for paper = 50