Office of Research
Research Management System (RMS)
• Online protocol submission for the IACUC is almost here!
• The software is in the final production stages and will be
available for use very soon!
• Take a look at the following slides to see how the online
system compares to existing paper forms…..
1
Old Protocol Form:
Application Section
A:
Title
B-F:
Personnel
G:
Funding
H:
Animal Numbers
I:
Procedures
J:
Hazardous Agents
K:
Controlled Substances
L:
Housing Locations (including outside of vivarium)
Narrative Sections
Section 1: Project Overview
Section 2: Justification/Rationale for Use of Animals/Lit
Search/Consideration of Alternatives
Section 3: Experimental Design
1. Rationale behind the experiments
2. Groups and number of animals per group
3. How number of animals was determined
4. Sequence and Timing of all Procedures
5. Procedural Endpoints
Section 4: Non-Surgical Procedures
Section 5: Surgical Procedures
Section 6: Clinical Signs/Pain and Distress/Monitoring and Management
Section 7: Drugs and Agents (tables)
Section 8: Euthanasia
Section 9: Personnel roles/responsibilities and training
Online AUP:
Basic information
about the protocol is
gathered together on
the General
Information tab:
funding/peer review,
lay summary and
Progress Report
Simple branching
questionnaires have been
incorporated into General
Information, replacing several
Appendices.
Old Protocol Form:
Online AUP:
Application Section
A:
Title
B-F:
Personnel
These two tabs are specific to
G:
Funding
certain kinds of protocols – if
H:
Animal Numbers
they don’t apply they can be
I:
Procedures
skipped.
J:
Hazardous Agents
K:
Controlled Substances
L:
Housing Locations (including outside of vivarium)
Narrative Sections
Section 1: Project Overview
Section 2: Justification/Rationale for Use of Animals/Lit
Search/Consideration of Alternatives
Section 3: Experimental Design
1. Rationale behind the experiments
2. Groups and number of animals per group
3. How number of animals was determined
4. Sequence and Timing of all Procedures
5. Procedural Endpoints
Section 4: Non-Surgical Procedures
Section 5: Surgical Procedures
Section 6: Clinical Signs/Pain and Distress/Monitoring and Management
Section 7: Drugs and Agents (tables)
Section 8: Euthanasia
Section 9: Personnel roles/responsibilities and training
Certification by PI
and Department
Chair is electronic
– no more wet
signatures!
This tab provide
information not
currently available to
researchers – where
your AUP is in the
review cycle!
Old Protocol Form:
Online AUP:
Personnel are added to the
Application Section
protocol on the Personnel tab,
A:
Title
by opening a drop-down list of
B-F:
Personnel
eligible personnel. Individuals
G:
Funding
are grouped together by
“teams” representing each
H:
Animal Numbers
laboratory
I:
Procedures
J:
Hazardous Agents
K:
Controlled Substances
L:
Housing Locations (including outside of vivarium)
Narrative Sections
Section 1: Project Overview
Section 2: Justification/Rationale for Use of Animals/Lit Search/Consideration
of Alternatives
Section 3: Experimental Design
Required training for
1. Rationale behind the experiments
Animal Use (CITI
2. Groups and number of animals per group
training modules) and
3. How number of animals was determined
LAOHP enrollment are
4. Sequence and Timing of all Procedures
automatically imported
5. Procedural Endpoints
and recorded within
Section 4: Non-Surgical Procedures
the AUP.
Section 5: Surgical Procedures
Section 6: Clinical Signs/Pain and Distress/Monitoring and Management
Section 7: Drugs and Agents (tables)
Section 8: Euthanasia
Section 9: Personnel roles/responsibilities and training
Old Protocol Form:
Online AUP:
Application Section
A:
Title
B-F:
Personnel
G:
Funding
H:
Animal Numbers
I:
Procedures
J:
Hazardous Agents
K:
Controlled Substances
L:
Housing Locations (including outside of vivarium)
Narrative Sections
Section 1: Project Overview
Section 2: Justification/Rationale for Use of Animals/Lit Search/Consideration
of Alternatives
Section 3: Experimental Design
1. Rationale behind the experiments
First define the species, then
2. Groups and number of animals per group
provide a justification/rationale
3. How number of animals was determined
and consider alternatives –
questions have been reproduced
4. Sequence and Timing of all Procedures
from the old forms (but
5. Procedural Endpoints
streamlined to remove
Section 4: Non-Surgical Procedures
redundancies)
Section 5: Surgical Procedures
Section 6: Clinical Signs/Pain and Distress/Monitoring and Management
Section 7: Drugs and Agents (tables)
Section 8: Euthanasia
Section 9: Personnel roles/responsibilities and training
Old Protocol Form:
Application Section
A:
Title
B-F:
Personnel
G:
Funding
H:
Animal Numbers
I:
Procedures
J:
Hazardous Agents
K:
Controlled Substances
L:
Housing Locations (including outside of vivarium)
Online AUP:
“Study Segments” are the individual
components of what was known as the
Experimental Design in the old forms –
but with step-by-step organizational
tools and a built-in animal numbers
calculator in table format. Each “study
segment” also includes procedural
descriptions for both surgical and nonsurgical procedures. As we move
forward, more IACUC-approved
procedural descriptions will be added
to the library, where they will be
available for copy-and-paste.
Narrative Sections
Section 1: Project Overview
Section 2: Justification/Rationale for Use of Animals/Lit Search/Consideration
of Alternatives
Section 3: Experimental Design
1. Rationale behind the experiments
2. Groups and number of animals per group
3. How number of animals was determined
4. Sequence and Timing of all Procedures
5. Procedural Endpoints
Section 4: Non-Surgical Procedures
Section 5: Surgical Procedures
Section 6: Clinical Signs/Pain and Distress/Monitoring
and Management
Section 7: Drugs and Agents (tables)
Section 8: Euthanasia
Section 9: Personnel roles/responsibilities and training
Monitoring for Pain/Distress
is described by experiment,
to ensure appropriate care
of animals. Endpoints and
euthanasia are also
described per experiment.
Office of Research
Stay tuned for updates!
7