USD2935
Pall Micro-24 Gas Micro Mixer
Precision control of oxygen and carbon dioxide
for micro-scale cell culture
The Pall Micro-24 Gas Micro Mixer accessory
creates additional gas regime control capability
at the microbioreactor scale, increasing the
precision of control of CO2 exposure for sensitive
mammalian cell culture applications. A very
simple touch screen interface controls the mixing
of up to three control gases - Oxygen, Carbon
Dioxide, and Nitrogen/ Normal Air - with precision
low-volume thermal mass flow controllers
(Figure 2). The user can access pre-set standard
configurations, or quickly and easily create
and store custom mixes of 2 or 3 gases. The
device supports very precise pH and dissolved
oxygen control while maintaining optimal CO2
concentrations in culture, stripping excess CO2
and maintaining minimal CO2 (Figure 3).
Features and Benefits
Features
Benefits
Easily mixes standard laboratory gases (O2, CO2, N2 or Air)
Eliminates acquisition and handling of mixed
gas cylinders, simplifies operations
Allows optimization of gas control strategies
Reduces evaporation, process instability,
and culture variability
More precise control of monitored (pH)
and unmonitored (CO2) process parameters
Prevents in process CO2 excursions
• Excess CO2 is stripped
• Minimal CO2 is maintained
Touch screen control interface
Easily create, edit, and store gas mixes,
rapidly access “standard” and saved gas mixes
Compact design
Laboratory bench, either behind Pall Micro-24 Microreactor
or beside Pall Micro-24 Microreactor. (Stand supplied
to add height for use behind Pall Micro-24 Microreactor)
LED strip under lid
Illuminating strip under the lid showing operating
state which can be seen from distance
Automatic purge
Performs a purge on all the gas lines
for a set period of time before use
Status messages display on screen
Status messages are displayed on screen during operation
to update the user. (Refer to manual for descriptions)
Figure 2. Touch Screen Control Interface
Figure 3. Gas Micro Mixer maintains optimal CO2 during culture
Touch Screen set to provide 3 separate gas mixes: pH control mix
with 50% N2 and 50% CO2, Purge mix of 5% CO2 and 95% N2 , and
Dissolved Oxygen Control mix with 21% O2 , 5% CO2 , and 74% N2
Gas mixtures maintain optimal Carbon Dioxide levels with minimal impact
to feedback control of Dissolved Oxygen and pH during culture.
2
Specifications
Gas Line Schematic Diagram
Power
110-240 VAC, 50/60 Hz self-switching
Input Gas Supply
Analytical Grade Oxygen, CO2, and N2 /Air
Max input pressure 8.27 bar/120 psi
Connections: 6mm Push-to-Connect
Note: The inlet pressure must be at least 750 mbar
(10.9 psi) higher than the required output pressure
Mixed Gas Outputs
pH: 0.25 – 25 sccm
Purge/ Inert: 0.1-10 sccm CO2 and 0.25-25 sccm N2 / Air
DO: 0.1-10 sccm CO2 + O2 and 0.25-25 sccm N2 /Air
Connections: 6 mm Push-to-Connect
Accuracy set points
Set point 0 – 10%
Set point 10 – 50%
Set point 50 – 100%
Gas Flow Accuracy and Stability
Environmental Requirements
Accuracy +/- 1.0%
Accuracy +/- 1.0%
Accuracy +/- 1.0%
Stability once gas mix has been set
Set point 0 – 10%
Stability +/- 0.5%
Set point 10 – 50%
Stability +/- 0.5%
Set point 50 – 100%
Stability +/- 0.5%
Stability achieved within 30 seconds
Operating Range +5°C to +40°C
Altitudes up to 2,000 m (6,500 ft)
Maximum relative humidity of 80% for temperatures
up to +31°C, decreasing to 50% at +40°C,
with no condensation
www.pall.com
3
Compliance
EMC Directive
2004/108/EC
Low Voltage Directive
2006/95/EC
Waste Electrical and Electronic Equipment
2002/96/EC
Reduction of Hazardous Substances
2002/95/EC
Safety requirements for electrical equipment for measurement,
control and laboratory use - Part 1: General Requirements
BS EN 61010-1: 2001
Electrical Equipment For Measurement, Control and Laboratory
Use - EMC Requirements - Part 1: General Requirements
BS EN 61326-1: 2006
Specification for Degrees of Protection provided
by Enclosures (IP Code)
BS EN 60529: 2000
Ordering Information
Description
Part Number
Pall Micro-24 Gas Micro Mixer
MRT-GMM-1
Visit us on the Web at www.pall.com/biopharm
E-mail us at bioreactors@pall.com
Corporate Headquarters
Port Washington, NY, USA
+1.800.717.7255 toll free (USA)
+1.516.484.5400 phone
biopharm@pall.com e-mail
European Headquarters
Fribourg, Switzerland
+41 (0)26 350 53 00 phone
LifeSciences.EU@pall.com e-mail
Asia-Pacific Headquarters
Singapore
+65 6389 6500 phone
sgcustomerservice@pall.com e-mail
International Offices
Pall Corporation has offices and plants throughout the world in locations such as: Argentina, Australia, Austria,
Belgium, Brazil, Canada, China, France, Germany, India, Indonesia, Ireland, Italy, Japan, Korea, Malaysia, Mexico,
the Netherlands, New Zealand, Norway, Poland, Puerto Rico, Russia, Singapore, South Africa, Spain, Sweden,
Switzerland, Taiwan, Thailand, the United Kingdom, the United States, and Venezuela. Distributors in all major
industrial areas of the world. To locate the Pall office or distributor nearest you, visit www.pall.com/contact.
The information provided in this literature was reviewed for accuracy at the time of publication. Product data may
be subject to change without notice. For current information consult your local Pall distributor or contact Pall directly.
© 2014, Pall Corporation. Pall and
are trademarks of Pall Corporation.
® indicates a trademark registered in the USA and TM indicates a common law trademark.
Filtration.Separation.Solution. is a service mark of Pall Corporation.
March 2014, PDF, GN14.5937
USD2935