Issued date: 14/December/2010
SAFETY DATA SHEET
LITHIUM HEPARIN
Document: SDS-DT-05-02
Page 1 of 5
1 Identification of the substance / preparation and of the company / undertaking
1.1 Product identification
Trade name:
Lithium Heparin
1.2 Application of the substance / the preparation
Anticoagulant. For diagnostic purposes only. It is not for
human consumption.
1.3 Manufacturer / Supplier
SYNTEX S.A.
Luis de Sarro 501 – Luis Guillón
Buenos Aires – Argentina
Tel. / Fax: 005411 4290-0609
http://www.syntexar.com
bulk@syntexar.com
1.4 Information in case of emergency
In case of Emergency call (005411)4290 0609 (ARGENTNA)
2 Hazards identification
2.1 Classification / 2.2 Labeling
Warning – May be harmful if swallowed and enter airways
May cause damage to the following organs: blood
May cause irritation to skin, eyes and respiratory tract.
Information concerning particular hazards for human and environment:
Risk phrases:
R20/21/22
Harmful by inhalation, in contact with the skin and if swallowed
R36/38
Irritating to eyes and skin
R43
May cause sensitization by skin contact
R48
Danger of serious damage to health by prolonged exposure
R65
Harmful: may cause lung damaged if swallowed
Safety phrases:
S23
Do not breathe dust or fumes
S24/25
Avoid contact with skin and eyes.
SYNTEX S.A.
Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 syntex@syntexar.com – www.syntexar.com
Issued date: 14/December/2010
SAFETY DATA SHEET
LITHIUM HEPARIN
Document: SDS-DT-05-02
Page 2 of 5
3 Composition / information on ingredients
Chemical characterization
Mucopolysaccharide
CAS. Nº Description
9045-22-1
Identification number(s)
EINECS Number:
232-681-7
MDN Number:
MFCD00131308
4 First aid measures
After inhalation:
Remove to fresh air and keep at rest in a position comfortable for breathing. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Inhalation of used
product should be considered a biohazard exposure incident.
After skin contact:
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if
irritation develops. Non-intact skin contact with used product should be considered a biohazard
exposure incident.
After eye contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of
water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Eye contact with used product should be considered a biohazard exposure incident.
After swallowing:
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Wash mouth. If large quantities of this material are swallowed,
call a physician immediately. Loosen tight clothing such as collar, tie, belt or waistband.
5 First-fighting measures
5.1 Suitable extinguishing agents
For small fire use DRY chemical powder. For large fire use water spray, fog or foam.
5.2 For safety reasons unsuitable extinguishing agents:
Do not use water jet.
5.3 Protective equipment:
Be sure to use an approved/certified respirator or equivalent.
6 Accidental release measures
6.1 Person – related safety precautions:
Wear suitable protective clothing, gloves and eye protection. Ventilate area of leak or spill.
6.2 Measures for environmental protection
Avoid dispersing dust into the air. Use non-sparking tools and equipment. Reduce airborne dust
SYNTEX S.A.
Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 syntex@syntexar.com – www.syntexar.com
Issued date: 14/December/2010
SAFETY DATA SHEET
LITHIUM HEPARIN
Document: SDS-DT-05-02
Page 3 of 5
and prevent scattering by moistening with water.
Small spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local
and regional authority requirements.
Large spill and leak: Use a shovel to put the material into a convenient waste disposal container.
Finish cleaning by spreading water on the contaminated surface.
6.3 Measures for cleaning / collecting:
Avoid dust elevation. Finish cleaning by spreading water on the contaminated surface and dispose
of according to local and regional authority requirements.
7 Handling and storage
7.1 Information for safe handling
Keep container tightly closed. Do not eat, drink or smoke when using this product. Wear protective
gloves and face protection. Avoid extreme temperature and heat.
7.2 Information about storage:
Keep container in a well ventilated and dry area at room temperature, preferable between 10 and
30 º C.
8 Exposure control / personal protection
8.1 Control Parameters
Information about design of technical facilities:
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne
levels below recommended exposure limits. If user operations generate dust, fume or mist, use
ventilation to keep exposure to airborne contaminants below the exposure limit.
8.2 Exposure control
Personal protective equipment:
Eye and Respiratory
protection
Protection of hands
Full suit
In case of spill
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus
should be used to avoid inhalation of the product.
9 Physical and chemical properties
General Information
Form:
Solid (powder)
Color:
White to yellow white
SYNTEX S.A.
Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 syntex@syntexar.com – www.syntexar.com
Issued date: 14/December/2010
Odor:
SAFETY DATA SHEET
LITHIUM HEPARIN
Document: SDS-DT-05-02
Page 4 of 5
Odorless
Change in condition
Melting point / range
Not Defined
Boiling point / range
Not Defined
Flash point
> 300 º C
Ignition temperature
Not Defined
Danger of explosion
Not Defined
Explosion limits
Not Defined
Vapour pressure at 20 ºC
Not Defined
Density at 20 º C
Not Defined
Specific Gravity (H2O=1)
0.7
Solubility in / Miscibility with
water at 20 ºC
Very soluble
Viscosity
Not Defined
10 Stability and reactivity
10.1 Reactivity
Not apply
10.2 Chemical stability
Stable at recommended storage conditions.
10.3 Dangerous reactions
Oxidizing agents, humidity
10.4 Conditions to be avoided
Avoid extreme temperature and heat.
10.5 Incompatible materials
Not apply
10.6 Dangerous decomposition products:
COx, NOx, SOx, LiOx, Emits toxics fumes under fire conditions.
11 Toxicological information
Acute toxicity:
LD / LC50 values relevant for classification
Oral
LD50
1900 mg / kg (mouses)
Primary irritant effect
On the skin: May cause skin irritation
On the eye: May cause eyes irritation
SYNTEX S.A.
Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 syntex@syntexar.com – www.syntexar.com
Issued date: 14/December/2010
SAFETY DATA SHEET
LITHIUM HEPARIN
Document: SDS-DT-05-02
Page 5 of 5
Sensitization: May cause respiratory tract irritation.
CMR effects (carcinogenity, mutagenicity and toxicity for reproduction): Not available
12 Ecological information
General notes:
Not available
13 Disposal considerations:
13.1 Waste treatment
Waste must be disposed of in accordance with federal, state and local environmental control
regulations
14 Transport information
14.1 ONU number
Not Apply
14.2 Proper shipping name
Heparin, lithium salt / Solid, organic powder.
14.3 Hazard class for
transportation
Xi Irritant
14.4 Packaging group
Packing Group III
14.5 Hazard for the media
Not Apply
15 Regulatory information
15.1 Labeling according to EU guidelines:
Not Apply
15.2 Security evaluation / NFPA Classification
HEALTH
FLAMABILITY
REACTIVITY
PERSONAL PROTECTION
1
1
0
F
May be irritating
Combustible if heated
Stable. Not reactive when mixed with water
Required
16 Other information
This information is based on our present knowledge. However, this shall not constitute a guarantee
for any specific product features and shall not establish a legally valid contractual relationship.
Version
Description of the change
02
Minor changes for EU compliance with the Regulation N° 453/2010
SYNTEX S.A.
Luis De Sarro 501 - (B1838DQK) – Luis Guillón – Buenos Aires – Argentina – Tel./Fax: (54 11) 4367-6100 syntex@syntexar.com – www.syntexar.com