TOKU-E issue date 09/01/2010 Penicillin G Potassium - MATERIAL SAFETY DATA SHEET Version 2.0 Revision Date 09/01/2010 1. SUBSTANCE IDENTITY AND COMPANY CONTACT INFORMATION Product Name Penicillin G Potassium Product Number P028 Procedure From Penicillium species Brand TOKU-E Company 715 W. Orchard Drive Suite 3 Bellingham, WA 98225 EMERGENCY PHONE (US only) +1-800-535-5053 INF +86-21-5206 9530 2. CHEMICAL COMPOSITION AND DATA ON COMPONENTS CAS NO. 113-98-4 Formula C16H17KN2O4S Molecular Weight 372.48 3. HAZARD IDENTIFICATION Label precautionary statements Harmful. May cause sensitization by inhalation and skin contact. In case of accident or if you feel unwell, seek medical advice immediately (show label when possible). Wear suitable protective clothing, gloves and eye/ face protection. 4. FIRST-AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous 1/6 TOKU-E issue date 09/01/2010 area. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If inhaled If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 5. FIRE-FIGHTING MEASURES Suitable Extinguishing media Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Special protective equipment for fire-fighters Wear self-contained breathing apparatus and protective clothing to prevent contact with eyes and skin. Unusual fire and explosion hazards Emits toxic fumes under fire conditions. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Environmental precautions No data available Methods for cleaning up Sweep up; avoid raising dust, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete. 7. HANDLING AND STORAGE Handling Wear Government approved respirator, chemical resistant gloves, safety goggles, and all other protective clothing. Do not breathe dust. Safety shower and eye bath. Mechanical exhaust required. Avoid prolonged or repeated exposure. Use only in a chemical fume hood. Storage 2/6 TOKU-E issue date 09/01/2010 Keep tightly closed. 8. EXPOSURE CONTROLS AND PERSONAL PROTECTION Contains no substances with occupational exposure limit values. Personal protective equipment Respiratory protection Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Handle with gloves. Eye protection Face shield and safety glasses Skin and body protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance White powder pH no data available Melting point no data available Boiling point no data available Flash point no data available Ignition temperature no data available Lower explosion limit no data available Upper explosion limit no data available Solubility no data available 3/6 TOKU-E issue date 09/01/2010 10. STABILITY AND REACTIVITY Storage stability Stable under recommended storage conditions. Conditions to avoid No data available Materials to avoid Acids, glycerol alcohol, heavy metal salts, oxidizing agents. Hazardous decomposition products Carbon monoxide, carbon dioxide, nitrogen oxides, and sulfur oxides. HAZARDOUS POLYMERIZATION will not occur. 11. TOXICOLOGICAL INFORMATION General No specific information is available in our database regarding the other toxic effects of this material for humans. May cause congenital malformations in the fetus. Potential Health Effects Skin May be harmful if absorbed through skin. Causes skin irritation. Eyes Causes eye irritation Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Ingestion May be harmful if swallowed. Target organ(s): No data available Signs and symptoms of exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Chronic exposure Mutagen Toxicity data: Oral Rat LD50: 8900 mg/kg Intraperitoneal Rat LD50: > 2 gm/kg Subcutaneous Rat LD50: 11250 mg/kg Intravenous Rat LD50: 243 mg/kg 4/6 TOKU-E issue date 09/01/2010 Intramuscular Rat LD50: > 2 gm/kg Oral Mouse LD50: 6257 mg/kg Intraperitoneal Mouse LD50: >2 gm/kg Intravenous Mouse LD50: 240 mg/kg Intramuscular Mouse LD50: > 2 gm/mg Oral Rabbit LD50: 5848 mg/kg Oral Guinea pig LD50: 374 mg/kg Intravenous Guinea pig LD50: 303 mg/kg Intramuscular Guinea pig LD50: 1180 mg/kg Only selected registry of toxic effects of chemical substances (RTECS) data is presented here. See actual entry in trees for complete information. 12. ECOLOGICAL INFORMATION No data available. 13. DISPOSAL CONSIDERATIONS Product Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state and local environmental regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods 15. REGULATORY INFORMATION US information Harmful. May cause sensitization by inhalation and skin contact. Wear suitable protective clothing and gloves. 5/6 TOKU-E issue date 09/01/2010 SARA list: No. TSCA inventory list: Yes. EU information: Harmful. R: 42/43 May cause sensitization by inhalation and skin contact. S: 36/37 Wear suitable protective clothing and gloves. Canada information This product has been classified in accordance with the hazard criteria of the CPR, and the MSDS contains all the information required by the CPR. DSL: Yes. NDSL: No 16. OTHER INFORMATION Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Toku-e Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. 6/6