Chapter 9.5 - Meiosis College Prep Biology Mr. Martino I. Introduction • Germ Cells: develop into sex cells (sperm and egg) • Gametes: mature sex cells – sperm and egg III. Sexual and Asexual Reproduction • Sexual Reproduction: reproductive process that includes the union of sperm and egg – Two parents – each donate a complete set of genes • Asexual Reproduction: production of offspring without the participation of sperm and egg – Single parent • Allele: unique form of the same gene (a gene) IV. Meiosis Halves Chromosome Number • Meiosis: nuclear division that divides chromosomes twice • Diploid number: (2n) pair of each type of chromosome – Homologous chromosomes: both chromosomes of a pair • Same length and shape • Genes are for same traits • Haploid number: (n) results from the second division of meiosis (sex cells) • Sister chromatids: two attached chromosomes – Once they pull apart, they are considered chromosomes • Meiosis consists of 2 divisions: – Meiosis I: DNA is replicated and divides – Meiosis II: another cell division without more chromosome doubling V. Stages of Meiosis • Meiosis: the process that produces haploid gametes (sex cells) – 2 consecutive divisions: meiosis I and meiosis II • Meiosis II is essentially the same as mitosis – 4 daughter cells produced – Only 1 duplication of chromosomes, second division halves chromosome number Interphase I • Like interphase in mitosis • Each pair replicates forming a 4 chromatid structure Prophase I • Most complex phase of meiosis • Lasts 90% of meiosis • homologous chromosomes form tetrads (4 chromatids) Structure of a Tetrad • Tetrad = structure consisting of 2 pairs of chromosomes – 2 chromosomal pairs = 4 sister chromatids – Visible during Prophase I only Metaphase I • Tetrads align on metaphase plate Anaphase I • Begins as homologous chromosomes (still attached at centromere) separate and move towards opposite poles • Only tetrads are separated Telophase I and Cytokinesis • Chromosomes arrive at opposite poles • Cytokinesis results in 2 diploid cells • No DNA replication occurs between meiosis I and meiosis II Prophase II • Chromosomes must condense again since there was a pause prior to meiosis II Metaphase II • Chromosomes are aligned at metaphase plate Anaphase II • Begins when centromeres of sisters chromatids separate Telophase II and Cytokinesis • Nuclei form at opposite poles • Cytokinesis occurs • Forms 4 haploid daughter cells VI. From Gametes to Offspring • Spermatogenesis: sperm formation – results in 4 viable sperm • Oogenesis: egg formation – First meiotic division results in a polar body and a secondary oocyte – Second division results in 3 polar bodies and 1 egg – Polar bodies are reabsorbed – egg is viable VII. Meiosis and Mitosis Compared • Chromosomes of both replicate only once • Mitosis consists of one cell division and two diploid cells • Meiosis entails two cell divisions and four haploid cells • Mitosis and meiosis II are virtually identical 9.6 Meiosis Increases Genetic variation among offspring • Genetic variation – differences among the gene combinations in the offspring due to sexual reproduction • Assortment of Chromosomes – the aligning of chromosomes during metaphase I is random; which results in many possible chromosome combinations • Crossing Over – the exchange of genetic material in between homologous chromosomes; during prophase I when tetrads are present