ACTIVE HERPES – “ ELECTRIC EFFICACY IN THE TREATMENT OF THE HERPES SIMPLEX, ZOSTER AND GENITAL. Ernesto Mercado R.1, Minerva del Mar G.A1. Luis Manuel Hernández S.1, Lizbeth Martínez G.1 Ingeniería de Sistemas, SEPI/ESIME – Zac. , Instituto Politécnico Nacional, México. Emails: EMR: emercador@yahoo.com; MMGA: mine_mori@hotmail.com .LMO: ; LMG: Lizbeth.martiez@gmail.com: ABSTRACT: The medicine has dismiss the enormous potential of the electricity for microbe’s elimination in a safety way. The research talks about the treatment of the viral disease called Herpes in its three variants: Simplex, vaginal and Zoster (HSV1, HSV2, VHS3), which although not fatal, they occur in millions in the world ; they are painful, annoying and highly contagious. The technique used was electrical stimulation using two pads, a computer, an operational amplifier and a MyDAQ card; the main variables identified were: frequency, intensity of electric current, time and placement of the pads to pass current through the affected area. One of the advantages of starting with Herpes was to observe the injury easily (they all are superficial) and see the impact of technology on them. The treatment is simple, easy to apply, painless , without any risk for the person, and generate a positive, definitive, verifiable and fully deterministic results: " The disease is cured or not; no middle terms in between”. We tested the technique with patients having the three types of diseases listed above with positive results in almost all cases. In a way, we might say treatment is authorized by the FDA, in a sense that the device used, call TEN, it is authorized for release the pain, at levels managed by the stimulator, therefore is authorized to cure herpes too, which uses the same intensity. We do not have the lab equipment to prove the efficacy of the technique by using the HSV lab tests; these were replaced by images before and after the treatment, the register of the electrical variables used, and the observation throughout the time. Some examples of patients treated are shown. We can see that in general after 3 or 4 outbreak treatments, the total amount of virus has been eliminated. Index Terms—Virus, deterministic, simplex,zoster,genital, pads, time, electric current. frequency, Herpes 1 I. INTRODUCTION Humanity has misused the potential of electricity for the treatment of infectious diseases, there is no doubt that electricity kill a living being when stimulated with a high electrical current, this is science and has nothing to do with magic or a miracle cure. Take for example the case in which a person is lying in a bathtub and an electrical device connected to the electrical source fall inside, the person will suffer an electric shock and might die(5). In the herpes disease, the vesicle produced is the bathtub, and the virus is the person inside; when a pair of electrodes are connected to the person in a way to pass an electrical current throughout this part, the virus is electrocuted; there is nothing mysterious in this process. We treated 3 types of Herpes: Simplex, Genital and Shingles, either of these virus is very contagious when is active, ie: When there is an outbreak of blisters. Herpes simplex is the one appears on the lips, also known as cold sores or lips blister. Genital herpes appear in men as in women in its genitals and this is spread by sexual contact. Finally, Shingles appears in the body anywhere, literature says that if you had sufferer smallpox in the childhood, there is a 5 % probability of having shingles when you are older. These diseases have not cure at present, they are only treatable with antiviral drugs to release its damage. The Symptoms of this disease include pain, burning, stinging, itching, and vesicle rash or blisters. The outbreaks appear when the person has reduce his personal defenses, weather changes, stress, throat infections, etc. The technique of electrical stimulation is an original one, without use of any drug or any other similar application in the world for the treatment of this disease. The antecedents for this kind of cure goes to the beginning of the microbes researchers when the Italian monk Lazzaro Spallanzani(1927)(19) eliminated these with a spark of electric current passing through a microbe sample and watching how these twisted around themselves and finally died. More recently appear the name of Raymond Royal Riffe in 1927(23), discovering the viral cause of many 2 diseases and making an extraordinary microscope to watch them and see the elimination effect produced by the electric stimulus at the resonance frequency of the microbe. In 1974 appear in the market a device called TEN( Transcutaneous electrical nerves)(31) by which is possible eliminate the virus, but initially used to provide massage to the muscles and release the pain. In 1990 Franz Diethelm(6) patented a device to eliminate the simplex and zoster virus based on a micro controller. One of the advantages of the electrical treatment is the property to eliminate the virus from the body, they do not go back to hide in the cell of the nervous system. As you can see the advantages for the patient is enormous, he is the main beneficiary of the technique, in terms of cost , pain, time, efficiency and effectiveness. Figure I.1. Density variation of electrical current when pads are in parallel and planar position The figure 1 shows an image of the position of the pads, main elements for the stimulation process, and the passage of current when the pads are in a parallel position, maximizing the volume of stimulated tissue, creating a volume(a cube in this case), and when they are in the same plane, for instance, when they are set on the skin for the treatment. II. DIMENSIONS OF THE ELECTRICAL TREATMENT One of the most important aspects of electrical stimulation have to do with the independent variables or attributes involve in the process in order to find the best values to eliminate the virus. The most important variables founded were(15): 3 1. Electric current intensity This is the main dimension in the stimulation process ; to see how effective is the current intensity or maximum value needed to eliminate the herpes virus, first it was tested with a current value less than one milliampere(ma), using a pulse form signal ( see fig II.2). ; a very small one and very far away of the dangerous limits(60 to 100 ma )(5). Figure II.1. Intermittent stimulation by means of electric pulses of high intensity and short duration . 2. Stimulation time. This is the second important variable in the electrical treatment process, its not only necessary to apply the right intensity to effectively eliminates the virus, but sustain such intensity for some time. In this sense it is like any medicine, it is not enough to have the proper chemical to which the virus is sensitive but it is also necessary to keep treatment for several days. So you see this is an important aspects to consider. Current stimulation Time is approximately 5 to 15 minutes per site or injury. The form of the wave is not as important as the current intensity, this 4 has to be kept the values tested to eliminate the virus without affect the tissue itself. 3. FREQUENCY .Another highly relevant variable in the process of stimulation is the signal frequency and its relevance was not detected until it we knew more about the capacitive reactance of the tissue between the two pads . These aspect relates mainly with the cells of the body, the cell membrane gives protection against the electric current penetration and therefore is necessary design a frequency wave who penetrate without damage the infected cell itself during the treatment, when the virus is in a latent form.. In the case of Herpes, stimulation frequency was 150 Hz using a TEN( Transcutaneous electrical nerves) because is its maximum available. Wave form . There are several types of waves commonly used in electronics, such as sine, square, triangle, pulse, etc. The main aspect is the current intensity carried out by each one of these forms, and what can be said on this, is that electric current intensity is proportional to the area under his shape; therefore the lower intensity belongs to the pulse, then triangle, sine and square form respectively. More research should be conducted to compare the efficacy of these when making an electrical stimulation to eliminate different types of virus or microbes . Sometimes the situation requires the use of a combination of two or more signals to achieve the desired goal. As the electrical treatment technique takes strength, it will go on taking into account new variables that must be considered. Figure II.2 shows the relevant dimensions in the process of electrical stimulation so far, each point in this space could be a specific microbe disease, and its coordinates, the corresponding values to eliminate it. The electrical stimulation process has not random variables , that is, generate a deterministic system , either, the disease is cured or not, there is no middle terms 5 or likelihood of cure; in other words, this means it is not necessary to determine a sample size of patients to validate the technique. Dimensions of the stimulation process Herpes case Frequency 150 Hz Bacterias Herpes Virus Funges 5 mins. Time stimulation 1 ma Current intensity Figure II.2. Dimensions of electrical stimulation. III. EFFECT OF ELECTRICAL FREQUENCY STIMULATION Figure III.1 depicts a blister and the liquid contained in it , the electrical current penetration in the cells depends on the frequency. Low frequency current only flows through out the extracellular space, it does not penetrate the cells containing virus, this is the kind of frequency generated by a TEN or TEN/EMS stimulator and can only be used to eliminate the active virus, those outside the cell. A known cell electric model is known as Cole-Cole(fig. III.1.), this has a circuit with two parallel branches: one contains a capacitor that simulates the capacitive 6 reactance of the cell membrane not allowing the current penetration, in series with a resistance simulating the resistance of the intracellular fluid. The other branch simulate the extracellular resistance. In the stimulation based on pads, there is a electrical branch or trayectory for each pair of points in the pads, therefore there are an infinite number of paths from one pad to the other , an electric network greater than those we have in any city in the world. Blister Pus Virus Electric current Celular Membrane Virus Cell b). Membrane resistance to the pass of electric current inside the cell Figure III.1. Electrical model relation of current flow at the cellular level intra and extracellular spaces; when active, the curent pass through the virus eliminting then, when hide, the current can not penetrate at interior of the cells. 7 Figure III.2. No penetration effect of current in cells, and the electrical model of a cell . 1.2 1 0.8 0.6 0.4 0.2 Freq. (Hz) 0 0 5000 10000 15000 20000 25000 Figure III.3. Resonance curve of the lips, current intensity at this frequency is more than 10 time the one at 100 hertz, keeping voltage at a constant value, this is the appropriate frequency to use in a cold sore or simplex case. 8 2 Current / ma Person 1 - F 1.8 1.6 Persona 3 -M 1.4 Persona 2 - F 1.2 1 0.8 0.6 0.4 0.2 Frecuencia 25,000 0 0 20000 40000 60000 80000 100000 120000 140000 160000 Figure III.4. Resonance curve in three person setting the pads at the arm; this would be the normal position in a zoster treatment case, using a voltage of 2 v(pp) : R = 25,000 hz Corriente 0.9 CUELLO Persona 1 0.8 0.7 0.6 Persona 2 0.5 0.4 0.3 0.2 0.1 0 0 5 10 15 20 25 30 35 40 45 Frecuencia Figura III.5 . Resonance frequency when pads are set on both sides of the neck usin a sine form : R ≈ 18,000 hz. 9 Figure III.3 to III.5 shows the resonance property of the tissue between two pads on the skin at different parts of the body; we are trying to use the resonance frequency property to eliminate the HPV by introducing current into the epithelial infected cells.. At this frequency the capacitive reactance of the tissue is minimized, and current flows in a higher level at low voltage reducing danger for the person. The resonance curve is an exponential form who has a maximum and decrease its value to zero after 20 or 30 KHz in an asymptotic way. R∞ piel Ri Res C ∞ iste nci a Res Ri Res C iste nci a Res iste R nci e a Ri piel iste R nci a Ri Res C ∞ iste nci a Res Ri Res C ∞ iste nci a Res Ri piel iste R nci e a iste R nci e a Ri piel R∞ piel Ri Res C ∞ iste nci a Res Ri Res C ∞ iste nci a Res iste R nci e a iste R nci e a Ri piel R + 10 Figure III.4.. Modeling the infinite trajectories of the electric current trough the body; every branch goes from one point of first pad to another point of the second pad. IV. RESULTS. a). The herpes’ virus, lips, Zoster and genital, are highly sensible to the electric current when is active; 1 mili ampere(ma), is enough to eliminate them( dangerous limits for alternating current are between 60 and 100 ma) when a pulse form is used; and 5 ma, when sinusoidal, square or triangular signal are applied. b). All the active virus at the injury are eliminated during the stimulation process in approximately 5 to 15 minutes per site. c) Not all virus remain at the initial infection site; only a small percentage stay there, the rest migrate to the interior of the nervous cells at different parts of the body and it is not known its exact place. We have found oral or simplex virus hidden on the head, under the hair. skin d) The outbreaks or reactivation , when there is one, it is due to the virus standing at their migration position from the nervous cells to the injury site, or remained in the interior of the cells of the nervous system without migration, and therefore they were not stimulated and eliminated. e) The size of the injury is proportional to the amount of virus in the body. In our experience during the first stimulation a percentage from 60 to 80 % of the total amount of virus in the body is eliminated( proved by visual inspection and photographs)., the eliminated virus were those at the injury; In a second outbreak treatment , which is obviously less severe because of the smaller amount of virus, the same amount of the remaining virus(60 to 80 % ) is eliminated ; and so far and so on, at the fourth it might finish more than 99 % of them. So, after the third or fourth treatment a lab test should result negative and no outbreak should appear again . As it can be seen it all depends on the time at which the stimulations is carry out. It is impossible to eliminate all of the virus in a single treatment due mainly to the absence of all of them at the site of the lesion, the lack of knowledge 11 about the place where they hide when they are quiet and the actual inability to penetrate at the interior of the cell at the moment.. f). The TEN used to generate the current is widely spread and is actually used to release pain or increase the muscles of the body. The intensity used has been approved by DEA, therefore the danger is minimal or null; just avoid a current trajectory does not pass through the eyes, tongue , brain and heart. Therefore, in some way, this implies an approval of the process stimulation by the DEA, and this might clear the situation for those highly worry about the legal facts, more than the cure of the patients . g). Very small knowledge is required to apply it, and almost every persons can do it with a few instructions. We have received letters from house keeper around the world asking for information about the free guide treatment, they go to the site : http://herpes-electrical-treatment.com, buy the required devices and cure themselves. h). The fundamental knowledge involved in the process fall mainly in the electrical field . i). The electric current inside the body tends to go in a way that minimize the electrical resistance between pads, and since this has low resistance once the skin has been penetrated (200 to 400 ohms, from any two points of the body)), the current tend to go in an almost straight path. j). The electricity generate a deterministic stimulation almost all patients process; this mean that properly treated, are cured; there is not middle terms or probability of cure. k) The results of the research is mainly directed to the ill persons, those suffering and asking for a cure. The validation of the technique has been through the photographs and visual inspection through 2 o 3 years, rather than lab test for each one of the virus(VHS1,2,3); a resource we do not have; the whole support has been conducted using our own salaries . 12 Figure IV.1.. Main variables registered during the treatment. l). The application of the technique is now expanding around the world, and many ill persons and doctors start its applications and confirming this facts reproducing the treatment process . m). The TEN device does not eliminate viruses at the interior of a cell, that is, does not eliminate the inactive virus; a different frequency might be required. n). A practical guide to use the technique can be found at the site : mentioned before under the option: “DESCARGA”(DOWNLOAD), and it is free. o). What really happens to each of the microbes during the electrical stimulation process? We assume is similar to what happens to a person when is accidentally electrocuted, that is, in the human case might occurs a ventricular fibrillation heartbeat, or a destruction of the cell’s tissue; therefore an alteration in the vital proceess of the virus must occur , or a complete destruction of its membrane tissue. p). The efficacy of the treatment is increased when the injury is stimulated at the resonance frecueny of the tissue between the two pads ; this is so because the current not only travel trough the fluids, but also through out the extracellular space 13 reducing the capacitive reactance of the tissue as a whole, not the single reactance of the membrane cell. This frequency is not provided by a TEN. V . PRACTICAL EXPERIENCES . LIPS BLISTER CASE(4) Figure V.1. It can be seen in the first image a lip blister, the second a completely healthy lip after three days applying the electrical stimulation The case showed in figure V.2 remark the effectiveness of the treatment. Figure V.2.. The first image shows vesicles on the lips, the right lip fully healed after a week of the treatment Patient was diagnosed since childhood with Herpes Simplex (HSV1), she had pain in the mouth and throat, sore neck, painful blisters on the lips and palate and swollen glands. She mentioned outbreak appears when she is in stress, fever, changes in climate and throat infections. As a result of the stimulation, patient had 14 an excellent result, before stimulation she could not even eat anything for the palate’s pain; after a day blisters on palate had desapered. We stimulated the nerves in the face, swollen, lips and palate. It was observed that after treatment on the lips pain had subsided. HERPES: ZOSTER CASE Patient diagnosed as having Herpes zoster, she had a history showing diabetes and a breast cancer operation 8 years ago, and had an herpes outbreak almost every month with blisters, burning, stinging, itching and pain. Herpes disease Figure V.3.. Treatment using a TEN stimulator (150 Hz) in a person with Herpes Zoster (a) Before stimulation, (b) Four days after .stimulation. . Figure V.4.. Stimulation at 20,000 hz in an Herpes zoster case, and image 4 days after in the same patent shown in figure V.3. appears when there is stress, heat and weakness, the blisters were located at the buttocks and back. We should note that a diabetic person having any injury takes a lot more time to heal; in this case we could see she responded very fast to the treatment by electrical stimulation. 15 HERPES ZOSTER – TWO SEVERE CASES Figure V.5. shows a severe case of herpes zoster treated through out a hidro electrical stimulation, one pad is inside the water y the other on the upper part of the arm; a single 20 minutes session was used to eliminate the active herpes and therefore the visual injuries . The figure 1V.6 is a similar case with great success since the first treatment. Figure V.5.. A severe case of herpes zoster; its hydro electrical treatment, and an image after 12 days of a single 20 minutes stimulation Figure V.6. A severe case of herpes zoster in which the first treatment eliminate more then 99 % of the total virus in the body; second reactivation appear one week later with only four blisters at the border of the previous lesions and the third with only one, six months later. 16 VI. TREATMENT PROCESS The herpes’s electrical treatment in any of its forms is highly effective, sure and uses the electric field knowledge as well as the approval of the FDA for the use of the device call TEN. Many people in the world is now downloading the free guide to do so, to cure themselves; that is, they are reproducing the treatment and verifying it really works. Pad’s position. This is part of the stimulation process and its impact depends mainly on the site to be stimulated and its proximity to another highly sensitive parts of the body to the current, as the heart, eyes, tongue or brain. The main idea is to set the pads to force current go across all the infected tissue in his way, keeping in mind that electric current always goes from one pad to the other. The figures VI.1. show how to stimulate a lips blister on both sides of the mouth, as well as the position during the treatment. Pads must be in each position for a period between 5 to 10 minutes; one the pads is always on the blisters and the second may be on one site(1 or 2 inches away). For 5 minutes; later second pad is changed to the other side or above or below of the first for another five minutes. Care must be taken to get away from the eyes, heart or ear nervous. Intensity. This must be set to 1 ma in case of a pulse wave form is used, or to 5 ma if a triangular, sine or square are applied. This values are proved to be effective with no danger for the people when pads are 4 * 4 centimeters; if the pad is larger or shorter, the intensity must be scale linearly according to the area of the pad; for instance if the pad is now 5*5 instead of 4*4 centimeters, its area is now 25 cm2, which is 56 % higher than the first one, therefore the current intensity most be increased 56%; that is , instead of 5 ma, 5 + 0.56 * 5 = 7.8 ma should be used in order to keep the same current density . 17 Figure VI.1.. Process stimulation for a lips blister. Frequency. This must be set to the higher value provided by the TEN(150 or 200 hertz) Pad’s disposal. They must be discarded in a safety way and no used them again, specially the pad touching the blisters; the other could be applied again. Face treatment. Special care must be taken when you treat some parts of the face to avoid an injury to the ear or eyes nervous, see figures VI.2 and VI.3. shows the appropriate positions when the herpes affect the face. 18 2 2 1 1 3 5 5 3 4 4 Figure VI.2.. Right positions of the pads for face’s treatment; every position : (1,1), (2,2),.., is illustrated by a couple of pads. . 19 2 1 3 3 2 1 Figure VI.3.. Prohibited positions for the pads, it is seen that current goes through the eyes. VII. Conclusions The main result obtained from the research shows that microbes, particularly virus, are sensible to the pass of an electrical current through out them, and therefore exists an intensity that eliminate them without causing any damage to the tissue. Many of articles in the electrical field show that current start damaging the body at levels between 60 and 100 ma with alternating current, far away from the 1 or 5 ma used in the treatment. The technique is deterministic and almost 100 % effective, almost all the patients treated were cured. So far, many persons and some medical doctors in the world started to use the techique in a succesfully form. A new signal at the resonance frequency of the infected tissue is testing now in order to eliminate the virus hidden or latent . We expect some of the readers will have the necessary equipment ánd a lab to carry out the necesasary test(VHS1,2,3) to verify the results in a different way. Actual research shows the 20 herpes virus might be the cause of mortal illneses, such as diabtes, Alzheimer and auto inmune, and this increase the relevance of the herpes virus elimination(2,3,10,11). 21 REFERENCES 1. Arthur Mathewson. Treatment of Cases of Herpes Zoster Frontalis by Electricity. Trans Am Ophthalmol Soc. 1874; 2: 228– 231. PMCID: PMC1361652. 2. P. Aldaz1,2,3, J.A. Díaz4, J.R. Loayssa5, M.J. Dronda1, M. Osacáriz1,3, J. Castilla. 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