The Chemistry of Life 2.1 Introduction to Chemistry 2.1 Introduction to Chemistry elements - make up earth & organisms (O, C, H, N, S, P, K, Si, Al, Fe, Ca) cannot be broken down by a chemical process into a simpler substance 2.1 Introduction to Chemistry Compounds - combinations of elements (ex. Hemoglobin (compound) contains Fe (element) Organic compounds - all contain carbon -ex. Carbohydrates, lipids, proteins, nucleic acids 2.1 Introduction to Chemistry inorganic compounds - do not contain carbon (ex. Table salt = NaCl) C6H12O6 – 24 total atoms 6 carbon atoms 12 hydrogen atoms 6 oxygen atoms How many atoms are in this molecule? C55H72MgN4O5 137 2.1 Introduction to Chemistry Atoms - smallest particle of an element that has the elements properties protons (+) = Atomic number neutrons (no charge) Protons and neutrons together make up the nucleus electrons (-) – used to form bonds with other elements 2.1 Introduction to Chemistry Changes in the number of electrons causes atoms to become + or – Outer most energy level (orbit) likes to be full – more stable that way Atoms will give up, gain, or share electrons to fill the outer orbit 1st level – 2 electrons 2nd level – 8 electrons 3rd level – 8 or 18 electrons 2.1 Introduction to Chemistry Sodium – 11 protons and 11 electrons 2 electrons in the 1st level 8 electrons in the 2nd 1 electron in the 3rd 2.1 Introduction to Chemistry Chlorine – 17 protons, 17 electrons 2 electrons in the 1st level 8 electrons in the 2nd level 7 electrons in the 3rd level Sodium wants to give up the last electron whereas Chlorine wants to gain an electron to fill the 3rd level with 8 electrons Atoms bond with other atoms to become more stable 2.1 Introduction to Chemistry 21. Introduction to Chemistry IONIC BOND 2.1 Introduction to Chemistry Ions - atoms that gain or lose an electron and have a charge 2.1 Introduction to Chemistry Chemical Bond -The force that holds atoms together When a chemical bond is broken, energy is absorbed or released IONIC BONDING Electrons are lost by one element and gained by another Outer energy level in both elements is full (stable) 2.1 Introduction to Chemistry 2.1 Introduction to Chemistry Ionic bond- a bond b/w oppositely charged molecules One element loses e- & the other element gains e Covalent bond – a bond where electrons are shared (carbs, lipids, proteins & nuc. Acids); three types: single, double, triple COVALENT BONDING Electrons shared in a chemical bond (each atom donates one electron) Outer energy level in both elements is full (stable) Double covalent bonds have four electrons Triple covalent bonds have six electrons COVALENT BOND 2.1 Introduction to Chemistry Polar Covalent – bond w/ unequal sharing of electrons that results in slightly positive & slightly negative ends Water – example of covalent POLAR COVALENT NONPOLAR COVALENT COVALENT VS. IONIC 2.1 Introduction to Chemistry Hydrogen Bonds – bonds that hold molecules together rather than atoms These bonds are weaker than ionic or covalent bonds * like in water – hydrogen bonds are the force that holds water molecules together 2.1 Introduction to Chemistry 2.1 Introduction to Chemistry Isotopes - atoms of the same element that have a different number of neutrons 2.1 Introduction to Chemistry Isotopes - have an unstable nucleus that breaks apart giving off energy in the form of radiation used to tell age of fossils preserve food treat cancer 2.1 Introduction to Chemistry 2.2 Introduction to Chemistry Water is found in all living organisms Water is a polar molecule Being polar allows water to dissolve ionically bonded compounds easily When compounds dissolve in water they form a solution Living things are composed of 70-90% water 2.2 Introduction to Chemistry 2.2 Introduction to Chemistry Solutions --Water is known as the universal solvent Chemical properties of water are important b/c they allow it to form solutions (aka. Uniform mixtures) 2.2 Introduction to Chemistry Solute --That which is being dissolved (sugar) Solvent --That which does the dissolving (water) 2.2 Introduction to Chemistry Ionic Compounds --dissolve readily in water b/c water is polar Polar covalent compounds -dissolve in water 2.2 Introduction to Chemistry Cohesion – “sticking together” b/c of hydrogen bonding surface tension – Like a water strider walking on water Plants --have a xylem (straw-like tubes that carry water) where the water is pulled up! 2.2 Introduction to Chemistry Expansion – water expands when it freezes, which is opposite to most substances results in ice having a lower density than liquid water so the ice floats 2.2 Introduction to Chemistry -ponds “freeze on top” so organisms are able to live underneath -Problem for roads 2.2 Introduction to Chemistry Acids & Bases --Formed by ionic compounds in solution Acids – release Hydrogen ions (H+) in water (ex. HCl in stomach acid) 2.2 Introduction to Chemistry Bases – Produce hydroxide (OH-) ions in solution (ex. NaOH in soap & egg whites) Salts – yield other ions (ex. NaCl and KCl) When salt is dissolved in water; sodium & chlorine “disassociate” or temporarily separate 2.2 Introduction to Chemistry pH --“power of H+” -pH scale measures the concentration of Hydrogen ions Scale 0-14 acid: 0 to < 7 bases: > 7 to 14 2.2 Introduction to Chemistry Blood - 7.4 (lethal if more acidic than 7 and more basic than 7.8) Stomach acid - 2 A change in pH --in your body results in halting some enzyme functions 2.2 Introduction to Chemistry Acid rain --contains sulfuric acid and nitric acid Acid rain pH < 5.6 Acid rain washes away vital minerals from soil, kills aquatic organisms & strip nutrients from plants 2. 3 The Compounds of Life (most contain carbon) Carbohydrates - store energy & provide shape (composed of C,H&O) Starch - plants stored energy that is made of sugars (monosaccharides, disaccharides & polysaccharides) CARBON Carbon is important biological element because it can form four bonds with other elements and long chains or rings Polymer – large molecule made up of many smaller units like starch Monomer – unit that makes up polymer; glucose is the monomer for starch 2. 3 The Compounds of Life Glycogen - animals stored energy made from sugars (same saccharides) Cellulose - simple sugars that make structural carbos in plants GLUCOSE Monomer of starch, glycogen, and cellulose 2. 3 The Compounds of Life Lipids - long term energy storage; four types; not soluble in water Fats - provide insulation Wax - repel water Phospholipids - give structure to cell membranes 2. 3 – The Compounds of Life Steroids - cholesterol in cell membranes 2. 3 The Compounds of Life Proteins - large, complex molecules composed of many smaller molecules called amino acids (only 20 amino acids make different combinations & proteins) Amino acids are held together by peptide bonds to form proteins 2. 3 The Compounds of Life Proteins - make enzymes that help control chemical reactions (ex. Speed up digestion, releasing energy during cellular respiration, building up proteins 2.3 The Compounds of Life 1. Defense 4. Regulation 2. Movement 5. Transport 3. Structure 6. nutrition 2. 3 The Compounds of Life Nucleic Acids - large, complex molecules that contain hereditary or genetic info – two types monomer – nucleotide (made up of nitrogen base, phosphate, and sugar) 2. 3 The Compounds of Life DNA - carries instruction that control activities of cell (blueprint) 2. 3 The Compounds of Life RNA - make the proteins (builder) 2.4 Chemical Reactions and Enzymes Chemical Reaction – creation of new substances by breaking or forming chem. bonds Carbs broken for energy All chemical reactions involve energy (absorbed or released) 2.4 Chemical Reactions and Enzymes 2H2 + O2 2H2O _C6H12O6 + __ O2 __C02 + __ H2O 2.4 Chemical Reactions and Enzymes Reactions happen in living & nonliving things all the time can be sped up by increasing temp or by involving a catalyst Catalyst - in organisms are called enzymes (see sucrose example, fig. 2.15) Enzymes - break bonds others help form bonds 2.4 Chemical Reactions and Enzymes *Type of protein *Act as a catalyst, speeding up chemical reactions 1. Substrate- substance being changed by enzyme 2. Active site- region on enzyme where substrate attaches (this is the enzyme substrate complex) 2.4 Chemical Reactions and Enzymes 3. Substrate is altered (bond weakened) so that bond is broken 4. Products released and enzyme is unchanged (only the substrate changes) 5. Enzyme is free to bond with another substrate 2.4 Chemical Reactions and Enzymes *Enzymes work by either breaking or forming compounds *Enzymes work only within specific ranges of temperature and pH. *Enzymes catalyze specific reactions- only specific substrates will fit into the active site *Enzyme affected by high temperature *Enzymes are also affected by the concentration of the substrate and the enzyme Application: bee sting home remedymeat tenderizer (enzyme) on bee sting (protein in venom)