AP Biology Syllabus Curricular Requirements Page(s) CR1 Students and teachers use a recently published (within the last 10 years) college-level biology textbook. 3 CR2 The course is structured around the enduring understandings within the big ideas as described in the AP® Biology Curriculum Framework. 2, 3, 5, 6, 7, 8, 9 CR3a Students connect the enduring understandings within Big Idea 1 (the process of evolution drives the diversity and unity of life) to at least one other big idea. 4, 6, 7, 8 CR3b Students connect the enduring understandings within Big Idea 2 (biological systems utilize free energy and molecular building blocks to grow, to reproduce, and to maintain dynamic homeostasis) to at least one other big idea. 4, 5, 9 CR3c Students connect the enduring understandings within Big Idea 3 (living systems store, retrieve, transmit, and respond to information essential to life processes) to at least one other big idea. 5, 8 CR3d Students connect the enduring understandings within Big Idea 4 (biological systems interact and these systems and their interactions possess complex properties) to at least one other big idea. 5, 6, 7, 8, 9 CR4a The course provides students with opportunities outside of the laboratory investigations to meet the learning objectives within Big Idea 1 4, 5, 6, 7 CR4b The course provides students with opportunities outside of the laboratory investigations to meet the learning objectives within Big Idea 2. 4, 5 CR4c The course provides students with opportunities outside of the laboratory investigations to meet the learning objectives within Big Idea 3. 8 CR4d The course provides students with opportunities outside of the laboratory investigations to meet the learning objectives within Big Idea 4. 4, 6, 9 CR5 The course provides students with opportunities to connect their biological and scientific knowledge to major social issues (e.g., concerns, technological advances, innovations) to help them become scientifically literate citizens. 4, 5, 6, 7, 8, 9 CR6 The student-directed laboratory investigations used throughout the course allow students to apply the seven science practices defined in the AP Biology Curriculum Framework and include at least two lab experiences in each of the four big ideas. 4, 5, 6, 7, 8, 9 CR7 Students are provided the opportunity to engage in investigative laboratory work integrated throughout the course for a minimum of 25 percent of instructional time. 2 CR8 The course provides opportunities for students to develop and record evidence of their verbal, written and graphic communication skills through laboratory reports, summaries of literature or scientific investigations, and oral, written, or graphic presentations. 2,3 1 AP Biology Course Overview Advance Placement Biology is part of a nationwide program based on the belief that many students are ready for college work while still in high school, and their abilities should be recognized, encouraged and rewarded. As a college level course, the amount of material covered, as well as the complexity of the topics, will be high. It is the responsibility of the student to come to class each day having understanding of the previous day’s material. An ongoing unstated assignment, therefore, is to learn the material as it is presented. Students must be certain that they are willing to accept this challenge and be committed to keep up with the course work. Instructional Context AP Biology is a course available to juniors and seniors that have completed a full year of biology or honors biology and a full year of chemistry or honors chemistry. Some students have completed AP Chemistry. Class is held 5 days per week and each class is two 44 minute periods for a total of 88 minutes/day. AP Biology Content AP Biology is structured around four Big Ideas described in the Curriculum Framework. These encompass the core scientific principles, theories, and processes governing living organisms and biological systems. At least one of the Big Ideas will be incorporated in every lesson throughout the course. The four Big Ideas are: 1) The process of evolution drives the diversity and unity of life. 2) Biological systems utilize free energy and molecular building blocks to grow, to reproduce and to maintain dynamic homeostasis. 3) Living systems store, retrieve, transmit and respond to information essential to life processes. 4) Biological systems interact, and these systems and their interactions possess complex properties. Class discussions may be based on animations from various sources (textbook, CD’s, internet, etc.) to help the students visualize what they have read. Quizzes are interspersed throughout the unit and inform how instruction may need to be adjusted to improve student learning. The two goals of AP Biology are to help students develop a conceptual framework for modern biology and to help students gain an appreciation of science as a process. The ongoing information explosion in biology makes these goals even more challenging. Students are encouraged to focus on understanding important relationships, processes, mechanisms, and potential extensions and applications of concepts. The course provides opportunities to connect scientific knowledge to major social issues to help students become scientifically literate citizens. [CR 5] Hands-on labs will constitute at least 25% of instructional time [CR 7]. Students will have the opportunity to complete at least two lab experiences in each of the four big ideas. [CR 6] Many of these labs are inquiry based, and emphasize collaboration, development of hypotheses, data collection, analysis and presentation. Students will maintain a laboratory notebook that documents their investigations throughout the year. In addition to the lab notebook, a final reflective essay will be required. [CR 8] 2 Science Practices Students are required to keep a lab notebook and/or write summaries of observations. 1) The student can use representations and models to communicate scientific phenomena and solve scientific problems. 2) The student can use mathematics appropriately. 3) The student can engage in scientific questioning to extend thinking or to guide investigations within the context of the AP course. 4) The student can plan and implement data collection strategies appropriate to a particular scientific question. 5) The student can perform data analysis and evaluation of evidence. 6) The student can work with scientific explanations and theories. 7) The student is able to connect and relate knowledge across various scales, concepts, and representations in and across domains. Textbook and Resources Biology, 8th Edition, Campbell [CR 8] AP Biology Investigative Labs: An inquiry-Based Approach, The College Board, 2012 Various Websites Course Schedule Unit 1: The Nature of Science and the Chemistry of Life [CR 2] ~ 3 weeks Readings: Chapters 1, 2, 3, 4, 5, 8 Big Idea 1 is tied to Big Idea 4 in this introductory unit, the complexity of life, properties of living organisms and how evolution is the unifying theory of biology. Overview of Topics Scientific method and experimental design Explain what is meant by scientific theory Practice with data collection, analysis, and presentation Address problems in research, such as confirmation bias Emphasis on evidence collecting, why evolution is considered a unifying theory Identify basic elements of living organisms Describe water’s unique properties Describe the structure of organic compounds Understand the pH scale, redox reactions, and hydrolysis/condensation Apply the laws of thermodynamics to biological systems Explain how life maintains a high degree of organization Investigate enzyme structure and function 3 Activities 1) Design and conduct an experiment, create and revise hypotheses, organize data, present findings (SP) 2) Lead class discussion on experimental design by explaining the design process and identifying controls and variables (SP) 3) Conduct an experiment to determine the optimal pH and temperature of the enzyme catalase [CR 4d] 4) Develop concept maps and diagrams comparing protostomes and deuterostomes to gain an understanding of how taxonomy helps manage the diversity of life. [CR 8] 5) Participate in discussion where students submit a recent news article for discussion on techniques used, and implications for science and society [CR 5] Unit 2: Cellular Processes [CR 2] ~4 weeks Big Idea 2 is addressed in this unit and tied to Big Idea 1 with regard to the diversity of life. Big Idea 2 is also tied to Big Idea 4 in showing how complex processes maintain homeostasis. Readings: Chapters 6, 7, 9, 10 Overview of Topics Review basic cellular components, construct models comparing differences between prokaryote, eukaryote, animal, and plant cells Explain the concepts of selectively permeable as it applies to the cell membrane, distinguish between active and passive transport Define homeostasis and illustrate how transport is used to maintain an internal environment Understand the process by which the cell theory was developed Understand the Endosymbiosis theory and its connection to evolution [CR 3A] and [CR 3B] Understand the role of photosynthesis and cellular respiration in maintaining homeostasis Unit 2 Activities 1) 2) 3) 4) 5) 6) 7) Diffusion and Osmosis Lab [CR 6] Create cell models using post-it notes [CR 4B] Microscopy Lab: Comparing Plant and Animal Cells [CR 6] Cellular Respiration Lab (Connects Big Idea 2 to Big Idea 4) [CR 3B] and [CR 3D] Photosynthesis Lab [CR 6] Transpiration Lab (connects Big Idea 2 to Big Idea 4) [CR 3B] and [CR 3D] Group Presentations on Membrane Transport Student constructs models connecting the movement of molecules across membranes; completed as a presentation to the class, groups assigned a type of transport [CR 4B] 8) Discussion of the Endosymbiosis Theory which includes a summary essay [CR 3B] and [CR4B] Unit 3: Evolution and Phylogeny [CR 2] ~ 3 weeks Big Ideas: 1, 3, 4 Readings: Chapters 22, 23, 24, 25 4 Enduring Understandings 1A Change in the genetic makeup of a population over time is evolution. 1B Organisms are linked by lines of descent from common ancestry. 1C Life continues to evolve within a changing environment. 1D The origin of living systems is explained by natural processes. 3A Heritable information provides for continuity of life. 3C The processing of genetic information is imperfect and is a source of genetic variation. 4C Naturally occurring diversity among and between components within biological systems affects interactions with the environment. Overview of Topics How natural selection serves as a mechanism for evolution Scientific evidence supporting evolution Hardy-Weinberg equilibrium Origin of Life, Fossil Records, Concepts of speciation Current event in evolution, resistance to antibiotics, pesticides, artificial selection Activities 1) Evolution of Grabbers – simulation, mutations and selection strength (Connects Big Idea 1 to Big Idea 3 and {CR 3C] to Big Ideas 1 and 4 2) Sex and the Single Guppy – laboratory simulation where students explore sexual selection (Connects Big Idea 1 to Big Idea 3) [CR 3A] and [CR 3C] 3) Discussion on how evolution relates to current science and biotechnology [CR 5] Learning objective 1.5: Student is able to connect evolutionary changes in a population over time to change in the environment by obtaining news articles and providing a summary and leading a class discussion [CR 4A] 4) Concept map on Evolution showing the processes that lead to its establishment as a theory. Uses PBS videos “Darwin’s Dangerous Idea” and “What Darwin Never Knew.” [CR 4A] 5) Construct a cladogram and phylogenic tree. [CR 4A] 6) Reconstruct a fossil record to further understand geologic time and extinction. [CR 4A] Unit 4: Organism Form and Function [CR 2] ~ 2 weeks Big Ideas 1, 2, 4 Readings: Chapters 40, 41, 42, 44. 45 In this unit, comparative anatomy is strongly emphasized and includes the dissection of athe rat as a comparison to human anatomy. Big Idea 1 is tied to Big Idea 4 as comparative anatomy emphasizes the relationships between organisms and similarities that imply common descent. [CR 3A] and [CR 3D] Enduring Understandings 1B Organisms are linked by lines of descent from common ancestry. 2A Growth, reproduction and maintenance of the organization of living system; require free energy and matter. 5 2C Organisms use feedback mechanisms to regulate growth and reproduction and to maintain environment. 2D Growth and dynamic homeostasis of a biological system are influenced by changes in the system’s environment. 2E Many biological processes involved in growth, reproduction and dynamic homeostasis include temporal regulation and coordination. 3E Transmission of information results in changes within and between biological systems. 4A Interactions within biological systems lead to complex properties. Overview of Topics Feedback control lops in animals Thermoregulation in animals Energy allocation and use in animals Examples of functioning units in mammal systems (alveoli in lungs, mephrons in kidneys) Structure and function in body systems (nervous, digestive, skeletak, urinary) Advances in medicine [CR 4C] and [CR 5] Activities 1) 2) 3) 4) 5) Dissection of the rat and comparative anatomy [CR 6] Exploration of the kidney [CR 4D] Dissection of a sheep brain, virtual exploration of a human brain [CR 4A] Comparing rat, horse and human skeletons Daphnia lab [CR 6] Unit 5: Pathology [CR 2] ~ 4 weeks Big Ideas; 1, 2, 4 Readings: Chapters 19, 27, 28, 43 Enduring Understandings 1C Life continues to evolve within a changing environment. 2B Growth, reproduction and dynamic homeostasis require that cells create and maintain internal environments that are different from their external environments. 4B Competition and cooperation are important aspects of biological systems. 4C Naturally occurring diversity among and between components with biological systems affects interactions with the environment. Overview of Topics Anatomy of Bacteria Diseases caused by Viruses, Protists, and Bacteria Viral and Bacterial Evolution Vaccines and Antibiotics Social issues and disease transmission [CR 5] 6 Activities 1) Bacteria Lab with Gram Stains [CR 5] 2) Group presentation on a Pathogen [CR 8] which includes final essay on emerging diseases, pathogens and their hosts. This connects Big Idea 4 (interactions) and enduring understanding 4B (competition) to Big Idea 1 (evolution) [CR 3D] and [CR 3A 3) HIV and immunology; how to find a cure for a rapidly evolving virus [CR 4A] Ties Big Idea 1 to Big Idea 4 [CR 3D] and [CR 3A] Unit 6: Inheritance [CR 2] ~ 4 weeks Big Ideas 1, 2, 3, 4 Readings: Chapters 12, 13, 14, 15 Enduring Understandings 3A Heritable information provides for continuity of life 3B Expression of genetic information involves cellular and molecular mechanisms. 3C The processing of genetic information is imperfect and is a source of genetic variation. 3D Cells communicate by generating, transmitting and receiving chemical signals. 4C Naturally occurring diversity among and between components within biological systems affects interactions with the environment. Overview of Topics Mitosis, Meiosis and the Cell Cycle What is cancer? Mendelian genetics (Laws of Segregation, Independent Assortment, Dominance) Mathematical predictions (Punnett squares) and Chi Square Analysis Chromosomal Patterns of Inheritance (sex linkage) Human Genetic Disorders Activities 1) 2) 3) 4) 5) 6) 7) Modeling of the Cell Cycle [CR 4C] Microscope observations of mitosis and meiosis [CR 6] Fruit fly lab [CR 6] Dihybrid Corn with Chi Square analysis [CR 6] Practice genetic problems [CR 4C] Hardy-Weinberg problem set: survey of human traits [CR 4C] Chromosome Simulation – using beads and pipe cleaners, demonstrate linkage groups and inheritance patterns [CR 4C] 8) Genetic Disorders Presentation [CR 4C] 7 Unit 7: Molecular Genetics [CR 2] ~ 3 weeks Big Ideas: 1, 2, 3, 4 Readings: Chapters 16, 17, 18, 20 Enduring Understandings 1A Change in the genetic makeup of a population over time is evolution. 2C Organisms use feedback mechanisms to regulate growth and reproduction and to maintain dynamic homeostasis. 2E Many biological processes involved in growth, reproduction and dynamic homeostasis include temporal regulation and coordination. 3A Heritable information provides for continuity of life. 3B Expression of genetic information involves cellular and molecular mechanisms. 3C The processing of genetic information is imperfect and is a source of genetic variation. 4A Interactions within biological systems lead to complex properties. Overview of Topics DNA is the genetic material (historical experiments, DNA structure and function, DNA replication) Flow of genetic information (genetic code, role of other polymers, transcription, translation) Mutations Gene expression (operon systems in prokaryotes, eukaryotic gene expression) Restriction enzymes, plasmids, transformation DNA technology (how gel electrophoresis works and applications of this technology) [CR 5] Biotechnology: stem cells, synthetic biology, genetically modified foods [CR 5] Activities 1) 2) 3) 4) 5) 6) Recombinant DNA simulation [CR 4C] Bacterial Transformation [CR 6] – Also ties Big Idea 3 to Big Idea 1 [CR 3A] and [CR 3C] DNA Concept Map [CR 4C] DNA Modeling, showing transcription and translation [CR 4C] Gel Electrophoresis [CR 6] Class discussions on biotechnology, student led discussions [CR 5] Unit 8: Ecology and Bioethics [CR 2] ~ 4 weeks Big Ideas 1, 2, 3, 4 8 Readings: Chapters 52-56 and selected articles chosen by students Enduring Understandings 1A Change in the genetic makeup of a population over time is evolution. 1C Life continues to evolve within a changing environment. 2A Growth, reproduction and maintenance of the organization of living systems requires free energy and matter. 2C Organisms use feedback mechanisms to regulate growth, reproduction and dynamic homeostasis. 2D Growth and dynamic homeostasis of a biological system are influenced by changes in the system’s environment. 2E Many biological processes involved in growth, reproduction and dynamic homeostasis include temporal regulation and coordination. 3E Transmission of information results in changes within and between biological systems. 4A Interactions within biological systems lead to complex properties. 4B Competition and cooperation are important aspects of biological systems. 4C Naturally occurring diversity among and between components within biological systems affects interactions with the environment. Overview of Topics Populations and Communities Population growth models Biodiversity and sustainability Biomes and Ecosystems Energy flow and chemical cycling Primary productivity Activities 1) Biome Project – student presents a biome, discussing its characteristics and challenges [CR 5] 2) Student led discussions on environmental topics; students share relevant articles and lead class discussions [CR 5] 3) Dissolved oxygen and Primary Productivity Lab [CR 6] 4) Human Demography study calculating birth and death rates [CR 4D] 5) Animal Behavior lab [CR 6] 6) Dandelion Population Lab – outdoor survey and mathematical analysis Learning Objective 4.19 The student is able to use data analysis to refine observations and measurements regarding the effect of population interactions on patterns of species distribution and abundance. 9 Science Practices Matrix for Major Labs SP 1 Use representations and models Scientific Method, Crickets SP 2 SP 3 SP 4 SP 5 SP 6 SP 7 Use mathematics Engage in scientific questioning Plan and implement data collection strategies Perform data analysis and evaluation of evidence Work with scientific explanations / theories Connect and relate knowledge X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X Enzyme Lab Osmosis and Diffusion X X Chromatography Transpiration Cellular Respiration X X X Microscopy Lab X X X Sex and the Single Guppy X X X X X X X X X Daphnia Lab X Dissection X X Microbiology Lab X X X Fruit Fly Lab X X X Hardy Weinberg Activity X X Gel Electrophoresis DNA Simulations X X X X X X X X X X X X X X X X X X X X X X X X X X Animal Behavior Populations Studies X X X X X X X X X X X X X 10