1. Concept of Evidence Based Practice 2. Anatomy of Pectus Procedures and pain 3. Importance of Pectus pain management 4. Pectus Nuss procedure 5. Ravitch procedure 6. Post op goals of care 7. History of prior treatment 8. Establishment of a pain protocol 9. Team effort 10. Drugs of protocol 11. Results 12. Solutions Idea of using a protocol for pain management Witnessing the amount of pain post op Wanting to provide adequate pain management and improve patient outcomes Improving patient experience and satisfaction Successful management of a post procedural pain requires the use of numerous methods of pain control. These include epidural, PCA, NSAIDs and systemic opioids. This is the top priority and in turn effects patient satisfaction and can increase complication rates. By definition is using the best evidence possible with the most appropriate information available to make clinical decisions for individual patients and improve outcomes. Steps: 1. Formulate the question/s that need answers to satisfy the specific patient needs. 2. Retrieval of the necessary information to answer the question 3. Reading and assessing the retrieved information to answer the question 4. Carry out a decision. 5. Evaluation of the process to determine if optimal outcomes were achieved. A strong pain stimuli activates NMethyl-D aspartate (NMDA) receptors and produce hyperexcitibility of dorsal root neurons. This trigger induces central sensitization leading to the wind up phenomenon and pain memory thus causing pain. Adaptation of the WHO Analgesic Ladder First performed in 1987 by Donald Nuss to correct the deformity of Pectus Excavatum or “sunken chest” Involves insertion of a metal bar into the chest under the defect and then flipping it causing the chest to be popped up into a more anatomical position. This causes a dislocation and realignment of the costovertebral joints with the chest reposition. By abruptly elevating the sternum anteriorly a substantial amount of pain in the chest and back is generated in a skeletally mature adolescent. The pressure of the bar holding the chest in a new elevated position increases the magnitude of pain involving the dermatomes of T1-T10. A transverse incision is made between the nipples, and the offending costal cartilage is removed with remodeling of the sternum and then placement of the bar for stabilization. Sutures are then placed around the bar to secure it to the ribs. The bar remains in place for about 12 months. You are not able to see the bar on the outside of the chest. POD 0 Ketorolac (Toradol) Methocarbamol (Robaxin) IV Ondansetron (Zofran) Famotidine (Pepcid) Epidural POD 2 Oxycodone/acetamin ophen (Percocet) oxycodone (Oxycontin) Ibuprofen Methocarbamol (Robaxin) po Famotidine (Pepcid) po Miralax Prophylaxis: for gastric upset due to NSAID therapy Duration of therapy: 1 month post op Adverse Rx: dizziness, headache, constipation, diarrhea Dose 20 mg BID for 1 month MOA: inhibits histamine at H2 receptors and gastric parietal cells inhibiting gastric secretion Onset: 1 hour Max: 30 minutes (IV) 1-4 hours (oral) Duration: 10-12 hours Anti inflammatory Nsaid Duration of therapy: 1 month post op Adverse Rx: increased risk of gastrointestinal bleeding and perforation Dose: 10 mg/kg Q 6 hours MOA: inhibits cyclooxygenase 1&2 (Cox 1&2) enzymes decreasing the formation of prostaglandin precursors, has antipyretic, analgesic and anti inflammatory effects Onset 1 hour Max: 2-4 hours Duration: 6-8 hours (dose related) Non narcotic anti inflammatory agent, Nsaid Duration of therapy: POD 0 and POD 1 Adverse Rx: edema, hypotension, dizziness, drowsiness, headache Dose: every 6 hours for 24 hours post op then replaced with ibuprofen every 6 hours MOA: inhibits Cox 1&2 enzymes, decreases formation of prostaglandin precursors, antipyretic, analgesic, anti inflammatory Onset: 30 minutes (IV) Max: 2-3 hours (IV) Duration: 4-6 hours Treatment of muscle spasms associated with acute painful musculoskeletal conditions Duration of therapy: 1 month post op Adverse Rx: bradycardia, flushing, hypotension, syncope, dizziness, drowsiness, fever, headache Dose:15mg/kg/dose IV Q 6 hours POD0&1 then po MOA: causes skeletal muscle relaxation by general CNS depression Onset: 30 minutes Max: 1-2 hours Duration: 1-2 hours Used for around the clock management of moderate to severe pain when analgesic is needed for long period of time Duration of therapy: starts POD 2 and continues for 1 week after discharge Adverse Rx: orthostatic hypotension, drowsiness, dizziness, anxiety, chills, confusion, nervousness, twitching, abdominal pain, gastritis, vomiting and constipation Dose: 10 mg Q 12 hours MOA: binds to opiate receptors in CNS, inhibiting ascending pain pathways, altering perception and response to pain produces generalized CNS depression Onset: 12 hours Max: 12 hours Duration: 12 hours Percocet Percocet Pain spike Oxycontin Pain spike Relief of moderate to moderately severe pain Duration of therapy: 1 week post op Adverse Rx: circulatory depression, hypotension, dizziness, drowsiness, fatigue, headache, insomnia, skin rash, constipation, nausea and vomiting Dose: 1-2 Norco 5 Q 4-6 hours prn MOA: blocks pain perception in cerebral cortex by binding to specific receptor molecules and opiate receptors within neuronal receptors decreasing synaptic chemical transmission throughout CNS inhibiting flow of pain sensations in the higher centers Onset: 10-15 minutes Max: 60 minutes Duration: 3-6 hours Use as an osmotic laxative, prophylactic with narcotic use Duration of therapy: 1 month post op Adverse Rx: urticaria, abdominal bloating, cramping, diarrhea, flatulence, nausea Dose: 17gm daily MOA: osmotic agent causes water retention into stool increasing stool frequency Onset: 1-3 days Management of severe acute pain Duration of therapy: during hospitalization as PCA or prn dosing Adverse Rx: bradycardia, flushing, syncope, amnesia, agitation, anxiety, drowsiness, slurred speech, pruritus, rash, urticaria, constipation, nausea, vomiting, urinary retention, respiratory depression Dose: PCA or 2 mg Q 2-3 prn MOA: binds to opioid receptors in CNS causing inhibition of ascending pain pathways altering perception and response to pain producing generalized CNS depression Onset: 20 minutes Duration: 3-5 hours The degree of pain affects all measureable objective outcomes during their hospitalization Parents during hospitalization are asked about the control of their child’s pain and for 2015 the average is 88% controlled In patients less than age 12 or 40 kg Oxycontin is not used If they have a reaction to Oxycontin it is discontinued and the patient is monitored closely and alternate methods are use to control pain A future study is being researched at the present time If the Oxycontin causes over sedation it is held and other meds are added as needed Have only had 2 patients who developed gastric upset with the ibuprofen, so Pepcid became standard Constipation is averted with Miralax and if problems MOM is given and if no results suppository is next step Anguole, D, Rugyte,C, Kilds, A, Karbonskiene, A, Mantas,V, Drauskas, B. 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