Exercise Science

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Exercise Science
Section 7: The Cardiovascular and Respiratory
Systems
An Introduction to Health and Physical
Education
Ted Temertzoglou
Paul Challen
ISBN 1-55077-132-9
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This material may be used only in a course of study in which Exercise Science: An Introduction to Health and Physical Education (Temertzoglou/Challen) is the required textbook.
The Cardiovascular System
 Composed of:
 Heart
 Blood vessels
 Blood
 Functions:
 Delivery of O2, fuel, and
nutrients to the tissues of the
body
 Removal of CO2 and waste
products from the tissues
 Maintenance of a constant
body temperature
(thermoregulation)
 Prevention of infection
(immune function)
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The Heart
 Considered a “double-pump” and is divided into the right and left
heart; separated by the interventricular septum
 Right heart:
 pumps deoxygenated blood to the lungs (pulmonary
circulation)
 Left heart:
 Pumps oxygenated blood to the rest of the body (systemic
circulation
 Surrounded by pericardium (tough protective sac); allows heart to
expand and contract
 Epicardium lines outside of heart; endocardium lines inside of heart
 Made up of four separate chambers: atria (upper chambers) and
ventricles (lower chambers)
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The Vascular System and Blood
 Vascular System:
 A network of vessels that transport blood throughout the
body; vessels divided into four main categories:
 Arteries: carry blood away from the heart to different
organs
 Arterioles: regulate blood distribution to various tissues
of the body
 Capillaries: responsible for the exchange of gases and
nutrients with the tissues
 Veins (venules): return blood to the heart
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Summary of the Vascular System
Large veins
Medium veins
Large arteries
Medium arteries
Arteriole
Venules
Capillaries
Precapillary
sphincters
Capillary bed
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Arteries and Veins
Arteries – vessels that carry (oxygenated) blood AWAY from the heart
to the organs
Veins – vessels that carry (deoxygenated) blood TO the heart
Oxygenated blood contains oxygen which is being delivered to organs.
Oxygenated blood is bright red. Deoxygenated blood does not contain
oxygen, and is much darker and is often depicted as blue.
The heart is formed from myocardium, a specialized muscle tissue
which makes up the heart. It is similar to skeletal muscle, except it can
pass signals from cell to cell, so the heart cells all contract as a single
unit
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Structures of the Heart
Common Structures
Structure of right side
Structure of left side
Chordae tendinae
Superior and inferior vena cava
Aorta and thoracic (descending
aorta)
Papillary muscles
Right atrium
Left atrium
Interventricular
septum
Right ventricle
Left ventricle
Pulmonary artery
Pulmonary vein
Tricuspid valve
Bicuspid (mitral) valve
Pulmonary valve
Aortic valve
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The Internal Anatomy of the Heart
Aorta
Superior vena cava
Right pulmonary artery
Aortic semilunar valve
Right pulmonary veins
Pulmonary semilunar valve
Right atrium
Interventricular septum
Left pulmonary artery
Left pulmonary veins
Left atrium
Bicuspid (mitral) valve
Left ventricle
Chordae tendinae
Tricuspid valve
Papillary muscles
Chordae tendinae
Right ventricle
Papillary muscles
Inferior vena cava
Thoracic aorta (descending)
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Path of Blood Through the Heart
Aorta
Superior vena cava
Right pulmonary artery
Aortic semilunar valve
Right pulmonary veins
Pulmonary semilunar valve
Right atrium
Interventricular septum
Left pulmonary artery
Left pulmonary veins
Left atrium
Bicuspid (mitral) valve
Left ventricle
Chordae tendinae
Tricuspid valve
Papillary muscles
Chordae tendinae
Right ventricle
Papillary muscles
Inferior vena cava
Thoracic aorta (descending)
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The Heart – Electrical Conduction System
Sinoatrial (SA) node
Atrioventricular (AV) node
Internodal pathways
Bundle of His
(AV bundle)
Right and left
bundle branches
Purkinje fibres
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Excitation of the Heart
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Sinoatrial node (SA node):
 Specialized region of tissue found in wall of
right atrium of heart
 Location where electrical signals are initiated
(nicknamed the “pacemaker”)
Atrioventricular node (AV node):
 Passes electrical signal from atria into
ventricles
 Passes electrical signal to the bundle of His
(atrioventricular bundle)
Bundle of His pass electrical signal to the Purkinje
fibres
Purkinje fibres pass electrical signal to the
myocardium
The myocardium contract
 Leads to contraction of the heart
 Leads to the pumping of blood
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The Electrical Activity of the Heart

AN electrocardiogram (ECG)
measures heart activity
 Graphical representation of
electrical sequence of events
occurring with each contraction
of the heart
 Each wave generated during
contraction is named:
 P wave: represents
depolarization through the
atria
 QRS complex: represents
depolarization of the
ventricle
 T wave: represents
repolarization of the
ventricle
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Coronary Vessels – Anterior View
Aorta
Superior vena cava
Left pulmonary artery
Branches of left pulmonary artery
Branches of right
pulmonary veins
Pulmonary trunk
Left pulmonary veins
Right pulmonary veins
Right atrium
Right coronary artery
Left atrium
Anterior interventricular branch
of left coronary artery
Great cardiac vein
Small cardiac vein
Right ventricle
Left ventricle
Inferior vena cava
Thoracic aorta
(descending)
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The Coronary Arteries, veins and capillaries
 Coronary Arteries: divide multiple times, eventually so
small we call them arterioles, supplying all of the
myocardium with oxgenated blood.
 Capillaries: responsible for the exchange of gases and
nutrients with the tissues, they are arterioles that have
become so small they are only one cell thick. They
eventually join together and become coronary veins.
 Veins (venules): return deoxygentated blood to the
heart from the capillaries
 The vascular system is a network of vessels that
transport blood through the body
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Cardiac Cycle

Cardiac cycle: series of events occurring through one heartbeat
 Involves two phases:
 Diastole phase (relaxation)
 Heart fills with blood
 Systole phase (contraction)
 Heart contracts and ejects blood
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Blood Pressure
Systolic Blood pressure - pressure observed in the arteries during
the contraction of the heart
Diastolic Blood pressure - pressure observed in the arteries
during the relaxation of the heart
When blood pressure is reported (normal is 120/80), it is reported
as systolic/diastolic
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The Return of Blood from the Veins
 The skeletal muscle pump:
 Upon contraction of skeletal muscle, blood
is pushed/
massaged back to the heart because of
ONE WAY VALVES in the veins. The
muscles contract, and the only way for
blood to travel is forward (back to the
heart)
 The thoracic pump:
 With each breath, low pressure in the
chest, and pressure in abdomen increases
 This creates a difference in pressure
between the areas, and pushes blood
from the abdominal cavity into the thoracic
cavity, again with one way valves in veins
 The nervous system:
 Sends a signal to veins
 Veins constrict allowing more blood back
to the heart
The skeletal muscle pump
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Properties of Blood
 Two main components:
 Plasma
 Fluid component of blood (mostly water)
 Blood cells
 Red blood cells (erythrocytes)
 Made in bone marrow
 Transport O2 and CO2 in the blood
 Transport nutrients and waste
 Contain hemoglobin
 White blood cells (leukocytes)
 Less than 1% of blood
 Critical in the function of the immune
system
 Platelets
 Regulate blood clotting
 They are only fragments of cells,
which must be separated
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Plasma 55%
90% water
7% plasma proteins
3% other (acids, salts)
Formed elements
45%
>99% red blood cells
<1% white blood cells
and platelets
Cardiovascular Dynamics
 Cardiovascular system adapts to meet the demands that are placed on
it
 Heart adjusts amount of blood pumped by altering:
 Heart rate (HR)
 duration of each cardiac cycle
 Stroke volume(SV)
 volume of blood ejected by ventricles
 Cardiac output (Q) - volume of blood pumped out of left ventricle in
one minute
 HR  SV = Q
 Frank-Starling Law:
 Ability of the heart to stretch and increase the force of contraction
 Ejection fraction
 Measure of stroke volume calculated by use of a formula
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Blood Pressure
 Blood Pressure is the force exerted by the blood against the walls of
the arteries
 Measuring blood pressure: systolic pressure over diastolic pressure
 Systolic blood pressure:
 Pressure observed in the arteries during contraction phase
 Diastolic blood pressure:
 Pressure observed in the arteries during relaxation phase of
the heart
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Normal Blood Pressure


Normal blood pressure (BP): 120mmHg over 80mmHg
Hypertension – high blood pressure
 BP greater than
140mmHg over 90mmHg
 Factors affecting BP
 Diet
 Aerobic exercise
Bradycardia – a lower resting heart rate due to exercise and training
(Like Ms. Young-lee!)
Cardiovascular disease – Any disease associated with the
cardiovascular system (heart disease)
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Blood Flow Distribution
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Effects of Training (bradycardia)
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The Respiratory System
 Composed of structures that allow:
 Passage of air from outside the body to the lungs
 Gas exchange to occur
 Three main functions:
 Supply O2 to the blood
 Regulate blood pH (acid-base balance)
 Divided into two zones:
 Conductive zone
 Respiratory zone
 External Respiration – exchange of O2 and CO2
 Internal respiration – in tissues, where O2 is
delivered and CO2 removed
 Cellular respiration – cells use O2 to generate
energy
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 Remove CO2 from the blood
Respiratory System Structure
Nasal cavity
Mouth
Epiglottis
Pharynx
Larynx
Trachea
Right and left
primary bronchi
Smooth muscle
Secondary bronchi
Terminal bronchiole
Tertiary bronchioles
Respiratory bronchiole
Alveolar sacs
Pulmonary venule
Pulmonary arteriole
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The Conductive Zone
 The conductive zone is
composed of structures that
transport air to the lungs:
 Mouth and nose
 Larynx
 Trachea
 Primary and secondary
bronchi
 Tertiary and terminal
bronchioles
 Filters air taken in with each
breath
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The Respiratory Zone
 The respiratory zone is
composed of structures involved
with the exchange of gases:
 Respiratory bronchioles
 Alveolar ducts
 Alveolar sacs - grape-like
structures found within the
lungs, provide a large
surface area for the
diffusion of gases into and
out of the blood
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Mechanisms of Breathing
 Inspiration:
 Contraction of diaphragm (muscle between lungs
and abdomen, which contracts to lower pressure
in chest and lungs, which causes us to inpire air)
 Thoracic cavity expands
 Air pressure in thoracic cavity is lower than air
pressure outside the body
 Air rushes in to lungs to restore balance
 Lung pressure = atmospheric pressure
 Expiration:
 Alveolar sacs recoil as diaphragm relaxes
 Air is expelled
 Thoracic cavity reduces
 Lung pressure>atmospheric pressure
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Ventilation
 Ventilation (VE) is inspiration and expiration together
 More specifically, the volume
of air moved by the lungs in 1 minute
 Influenced by two factors:
 Tidal volume (VT)
 Volume of air in each breath
 Respiratory frequency (f)
 Number of breaths taken per minute
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Respiratory Control Centres
 Respiratory control centres found within brain stem include:
 Medulla oblongata
 Inspiratory centre
 15-20 breaths per minute at rest
 Expiratory centre
 Two main functions:
 Ensure the inspiratory muscles never completely relax
 Stimulate forceful expiration when required (during
exercise)
 Pons
 Pneumotaxic and apneustic centres
 Ensure smooth transition of inhalation to exhalation
 Fine-tune the breathing pattern
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Lung Volumes
 Lung Volumes are divided into two categories:
 Static lung volumes
 Determined by the actual structure of the lung
 Three important static lung volumes:
 Total lung capacity (TLC)
 Maximum volume of air that lungs can hold
 Sum of vital capacity
 Vital capacity (VC)
 Maximum amount of air that can be exhaled following
a maximal inhalation
 Residual volume (RV)
 Air that remains in lungs following a maximal
exhalation
 Dynamic lung volumes
 Dependent on volume as well as movement/flow of air
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Fractional Concentrations and Partial
Pressures of Main Gasses Found in Air
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Gas Exchange
 Diffusion mediates gas exchange (just like it sounds!)
 Diffusion is the movement of a gas, liquid, or
solid from a region of high concentration to low
concentration
 Can only occur if a difference in
concentration exists
 Concentration gradient
Partial pressures – a way to measure the
gases found during respiration
 Diffusion pathway
 Area through which gases move from the lungs
into the blood; from the blood into the tissue, and
back
 Rates of diffusion depend on:
 Size of concentration gradient
 Thickness of barrier between two areas
 Surface area between two areas
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Oxygen/Carbon Dioxide Transport
 Oxygen (O2) transport within the blood achieved in two ways:
 O2 dissolved within the plasma
 Represents 2% of O2 found in the blood
 Binds to hemoglobin
 Carbon dioxide (CO2) transport achieved in three ways:
 Trace amounts of CO2 dissolved within the plasma
 Binds to hemoglobin
 Bicarbonate system
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External and Internal Respiration
 External respiration is the result of two main factors:
 Increase in pulmonary ventilation (VE)
 Maintains necessary gradients in the partial pressures of both
O2 and CO2
 Increase in blood flow to the lungs
 Caused by and increase in cardiac output
 Internal respiration involves exchange of gases at tissue level –
extraction of O2 at tissues is increased
 Occurs as result of four main factors:
 Increase in partial pressure of oxygen (PO2) gradient
 Increase in partial pressure of carbon dioxide (PCO2)
 Decrease in pH
 Increase in temperature
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Flow of External and Internal Respiration
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a-vO2 Difference
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Lactate Threshold
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Oxygen Deficit and EPOC
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Physiological Adaptations Due to
Endurance Training
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 Henry’s law – the amount of gas that will dissolve or diffuse into a liquid
is proportional to the partial pressure and solubility of the gas
 Oxygen transport – O2 is transported by binding to hemoglobin, but
also is dissolved into plasma, however, that represents only 2% of the
o2 found in blood
 Blood pH – how acidic or basic blood is, generally maintained very
close to 7.4
 A-vO2 diff – difference between the amount of oxygen in the artery and
vein (ie. The amount of oxygen delivered to the muscle)
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Asthma
 Asthma (acute or chronic) is
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characterized by:
 Spasm of smooth muscle lining the
respiratory system
 Oversecretion of mucous
 Swelling of cells lining the respiratory
tract
 Asthma results in:
 Dyspnea (shortness of breath)
 Wheezing during breathing
 Factors that stimulate attacks:
 Exercise
 Allergic reactions/contaminates
 Stress
 Controlled through the use of
medications
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Chronic Obstructive Pulmonary Disease
 Chronic obstructive pulmonary disease (COPD):
 Describes a family of diseases that lead to a reduction in airflow




through the respiratory system
Often fatal in severe cases
Persistent conditions cannot be relieved (quickly or effectively)
through the use of medications
Individuals experience dyspnea while performing everyday
activities
Treatment includes:
 Medication
 Oxygen therapy
 Respiratory muscle training
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 Oxygen consumption – amount of oxygen consumed by the body for metabolic










processes
VO2 max – the maximal amount of o2 that can be taken in and used for the
metabolic production of ATP during exercise.
Respiratory Exchange ratio – the ratio between the amount of Carbon dioxide
expired and the oxygen used; shows how your body is using the gases it receives
Ventilatory threshold – the point where ventilation increases (because of lactic
acid) much more rapidly than workload, normally occurs at 65-85% of VO2 max
Lactic acid – by-product of anaerobic metabolic processes in the skeletal muscle;
used to be associated with fatigue and muscle soreness
Lactate threshold – the point where blood lactate concentrations rise
exponentially, resulting in very high concentrations, associated with the ventilatory
threshold
OBLA – when blood lactate levels accumulate rapidly
Oxygen deficit – the difference between oxygen required to perform a task and
oxygen actually consumed prior to reaching a new steady state
EPOC – oxygen used during exercise recovery
Hyperbaric Oxygen therapy (HBO2) – a person is placed in an HBO2 chamber to
help heal injuries; breathin air tht is 95 – 100% oxygen
Passive recovery (total rest) and active recovery (moderate aerobic activity – cool
down)
©Thompson Educational Publishing, Inc. 2003. All material is copyright protected. It is illegal to copy any of this material.
This material may be used only in a course of study in which Exercise Science: An Introduction to Health and Physical Education (Temertzoglou/Challen) is the required textbook.
©Thompson Educational Publishing, Inc. 2003. All material is copyright protected. It is illegal to copy any of this material.
This material may be used only in a course of study in which Exercise Science: An Introduction to Health and Physical Education (Temertzoglou/Challen) is the required textbook.
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