VisiMix Products

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VisiMix

Simulation of Mixing Processes

VisiMix Ltd,

PO Box 45170,

Jerusalem, 91450,

Israel

Tel: 972 - 2 - 5870123

Fax: 972 - 2 - 5870206

E-mail: info@visimix.com

VisiMix

Simulation of Mixing Processes

Presentation Contents:

- The Customers

- The Technology

- ROI

- VisiMix Products

- Saving Examples

About Us

VisiMix is a unique software enabling chemical engineers, process engineers and

R&D personnel to visualize mixing processes via a simple, user friendly interface.

Our products allow significant savings in time and costs by drastically reducing the need for trial-and-error. They have been successfully adopted by hundreds of companies.

Customers and Markets

Our Customers

What Our Customers Say About Us

From the Dow Chemicals Intranet Website

“VisiMix: This is a highly accessible PC software for mixing calculations available from VisiMix Ltd., an Israeli company. It is a rating calculation tool for both nonreactive and reactive mixing involving blending, solid suspension, gas dispersion, liquid-liquid dispersion, or heat transfer processes in stirred vessels. It calculates the important process parameters for single- and two-phase systems – power consumption, circulation rates, local concentrations of solutes and suspended particles, drop size, concentrations of reactants, etc … ”

Dr. Victor Atiemo-Obeng

Dow Chemicals Co.

What Our Customers Say About Us

“We have been using VisiMix. We have found it an accurate tool ...

Based on our success with the product, our Japanese colleagues at

Fuji Xerox have bought a copy for their work.”

Emily Moore,

Xerox Research Center of Canada

“I am very pleased in applying your software.”

L'Oreal, France

Customers and Markets

Customer List

1. L'Oreal, France

2. BASF AG, Germany

3. Dow Chemical Company, USA

4. Searle (MONSANTO), USA

5. Lightnin, USA

6. LG Chemicals, S. Korea

7. Xerox , Canada & USA

8. The Gillette Co., USA & UK

9. De Dietrich, France & USA

10. ENIChem, Italy

11. Eli Lilly & Company, USA

12. NIPPON, Japan

13. Novartis, USA

14. Millennium, USA

15. ICI, UK

16. Hercules, USA

17. Pfizer, USA&UK&Gr.

18. Mitsubishi Chemicals

19. Abbott Laboratories, USA

20. GlaxoWellcome,UK&Singapore

1. L'Oreal , France

2. Techmix S.r.o, Czesh Republic

3. BASF AG , Germany

4. BASF , Denmark

5. BP Chemicals - Wingles, France

6. Sanofi Recherche, France

7. Technimont, Italy

8. Nycomed Imaging, Norway

9. Hoesch & Sohne , Germany

10. DSM, The Netherlands

11. Searle (MONSANTO) , USA

12. Lightnin, USA

13. Chevron , USA

14. Teva, Israel

15. Plantex, Israel

16. Bromine Compounds, Israel

17. ENSIC, France

18. LG Chemicals, Taejon-city, S. Korea

19. LG Tech, Yeochon-city, S. Korea

20. Lonza, Switzerland

21. Thai Plastic and Chemical Public Company, Thailand

22. Xerox Research Centre of Canada , Canada

23. Xerox , USA

24. The Gillette Co ., USA

25. Gillette , UK

26. Lecaros, Chile

27. SK Chemicals, S. Korea

28. Dow Chemical Company , USA

29. Monsanto , USA

30. Buchi AG, Switzerland

31. Agisys, Hungary

32. Samsung , S. Korea

33. Mervers, Holland

34. American Cyanamid Company , USA

35. Belinka Belles, d.o.o., Slovenia

36. LG Chem. , ABS Division (S. Korea)

37. BFGoodrich Advanced Technology Group, US

38. PT MECO INOXPRIMA, Indonesia

39. Ion Exchange, India

40. IL JIN Eng. & Const. Ltd., Korea

41. CSIR Ltd., South Africa

42. PTI, Brazil

43. De Dietrich , France

44. De Dietrich , USA

45. Rhodia (Rhone Poulenc Group), Brazil

46. Inymassa, Spain

47. ENIChem , Italy

48. Satake, Japan

49. Chesebrough-Pond’s, USA

50. Unilever, Italy

51. Schering-Plough , USA

52. Ontec, Israel

53. Cytec, USA

54. Degussa, Germany

55. IHN Groningen BV, the Netherlands

56. PEAS BV, the Netherlands

57. Eli Lilly & Company , USA

58. BSL (Dow group), Germany

59. VMD PTE Ltd., Singapore

60. Tecnicas Reunidas, Spain

61. NIPPON, Japan

62. Chr. Hansen, Denmark

63. Danisco, Denmark

64. Novartis , USA

65. SNECMA, France

66. Millennium, USA

67. Ucosan B.V., Holland

68. Norde Veenendaal B.V., Holland

69. Akzo Nobel , Germany

70. Astra Charnwood, UK

71. ICI , UK

72. Stork, Netherlands

73. Hercules, USA

74. Luigi Menestrina, Italy

75. Siersma Leidshendam, the Netherlands

76. Sara Lee, the Netherlands

77. Pfizer , USA

78. Pfizer , UK

79. Pfizer , Germany

80. Beiersdorf AG, Germany

81. Sintef Applied Chemistry, Norway

82. Chemitec OY, Finland

83. Makhteshim, Israel

84. Chemagis, Israel

85. Nitto Denco, Japan

86. 3M , USA

87. Broom Chemie, the Netherlands

88. Atlas-Stord, Denmark

89. Canon , Japan

90. Mitsubishi Chemicals

91. Imation, USA

92. NIKKI, Japan

93. Fuji Xerox, Japan

94. Oxy Vynils

95. Scanlube, Sweden

96. GlaxoWellcome , Singapore

97. GlaxoSmithKline , UK

98. SmithKline Beecham , USA

99. M&F Process Simulation, The Netherlands

100. Abbott Laboratories , USA

101. Air Products , USA

102. Gruppo Lepetit, Italy

103. Johnson Polymer, Holland

104. Dow Corning, USA

105. Pharmacia Biotech, Sweden

106. Panandiker Research & Development (P) Ltd., India

107. Fujifilm , Japan

108. Katholieke Hogeschool Brugge-Oostende, Belgium

109. The Casali Institute, Israel

110. Noordelijke Hogeschool Leeuwarden, the Netherlands

111. Stettin University

112. Taiwan University

113. Ecole d'Electrochemie, France

114. Ecole Polytechnique, Canada

115. University of Western Ontario, Canada

116. University of Barcelona, Spain

117. Taejon National University, S. Korea

118. Otto von Guericke Universitat, Germany

119. Tsinghua University, China

120. VUOS, Czesh Republic

121. Universita di Roma, Italy

122. Hanyang University, S. Korea

123. Royal Institute of Technology, Sweden

Total : 123 customers

De Dietrich - Example

http://www.ddpsinc.com/MixingSimulations.htm

De Dietrich - Example

http://www.ddpsinc.com/Visimix.htm

Simple and Effective

Technology - Simulation of Mixing Processes

The First and the only tool in the Industry

Reliable and accurate results

Based on More Than 300 Man Years of R&D and

Industry Experience

Replacing Pilot Experiments

Accelerated Time-to-Market process

User Friendly and easily accessible

Simple and Effective

Return On Investment (ROI)

Per Year basis

Product Cost Benefits

(The ICI Example)

Savings

Per project - $20,000

Per year - $150,000

(5-10 projects per year)

Quality

Time

Time To Market

VisiMix Products

Introduction

VisiMix software:

• Based on advanced scientific knowledge and practical expertise

• User-friendly and easy to operate

• Requires easily accessible initial data

The latest VisiMix products are:

• VisiMix 2K8 Turbulent

• VisiMix 2K8 Laminar

• VisiMix 2K8 Different Impellers

• VisiXcel- Data Base

• Pipe Line

VisiMix Products

VisiMix Software Products

• VisiMix 2K8 Turbulent – for low-viscosity liquids and multiphase systems.

The program provides process parameters necessary for analysis, scaling-up and optimization of mixing tanks and reactors with all types of impellers

Calculations of:

 Blending

 Suspension

 Dissolution

 Emulsification

 Gas dispersion

 Heat transfer

 Chemical reactions

 Mechanical stability of shafts

VisiMix Products

VisiMix Software Products

• VisiMix 2K8 Laminar - for highly viscous media

 Newtonian and non-Newtonian

 Macro-scale blending

 Micromixing in high-shear areas

 Heat transfer

• pastes

• creams

• shampoos

• liquid soaps

• gels

• ointments

• paints:

• coatings

• slurries

• polymer solutions

VisiMix Products

VisiMix Software Products

• VisiMix 2K8 Different Impellers – for combined mixing devices

The program handles mixing devices consisting of any 2 – 5 impellers.

Different distances between impellers

Used in combination with VisiMix Turbulent.

Provides parameters of hydrodynamics, turbulence and heat transfer.

VisiMix Products

VisiMix Software Products

• VisiMix VisiXcel – Data Base (DB) – automatic conversion tool:

Visimix Output to Excel Spreadsheet

•Integrates VisiMix report parameters in standard Excel worksheets

•Analysis VisiMix results in Excel

•Builds a Database of mixing tanks and reactors.

•Builds a Database of projects - for processes

•Makes correlation between plant equipment nomenclature to VisiMix database of mixing tanks and reactors in VisiMix Project Database.

•Easy access to design data of the mixing tanks, to process parameters and to corresponding results of VisiMix modelling.

•Results of VisiMix mathematical modelling in the VisiMix VisiXcel-DB and arrange the data according to the reactor nomenclature.

• Easy access to recalculation of the VisiMix modelling from the

Database of the reactors & the projects

VisiMix Products

VisiMix Software Products

• VisiMix Pipe-Line

• Calculates hydraulic resistance of simple pipelines for liquid viscosity and non-Newtonian products .

Chemical engineers benefit from a quick and user friendly method for charging times and the bottle-necks in the line.

Includes : - Pipes - Riffled hoses – Elbows – Valves - And more

• Also comes with a database containing rheological constants for the typical commercial non-Newtonian products - pastes, creams, shampoos, paints, etc. ( see Help Section for details )

The first and only tool calculating flow resistance for liquids that correspond to Carreau rheological model. (See Help Section for details)

VisiMix Orientation

VisiMix Demonstration Tools

The VisiMix Demonstration Tools:

 VisiMix Turbulent – Examples & User Guide

 VisiMix Laminar - Examples & User Guide

 VisiMix Different Impellers – Examples & User Guide

 VisiMix Turbulent SV – Trial & Education

 VisiMix Review of Mathematical Models

 Selected Verification Examples

The Comparison between Published Experimental Data and

VisiMix Calculations

Saving Examples

Finance Saving Examples (ROI)

1. Cooling A Paste

2. Paints

3. Suspension in a Batch Reactor

4. Scale up Methodology

Finance Saving Examples (ROI)

Example

Cooling of a

Paste

Paste and

Coating

Case Classic Solution Visimix

Solution

Batch Production

Time

Mixing several components to obtain high quality paint during scaleup process

Replacement of the whole mechanical system

Increase the impeller speed and improve the heat removal in the tank.

No successful results obtained

Input the existing mixing systems parameters to

VisiMix software, implement small changes

Change agitator dimension for uniform mixing without overheating

Saving

$125,000 per year

$40,000 per year

Suspensions in a batch reactor

Plugging of the bottom valve of the reactor

Scale up

Methodology

Implementation during the Scale studies

Replacement of the agitator

Lower the impeller position

Calculation after finishing the development stage

Calculation during the development stage

$12,000 saved on the cost of a new impeller and for all associated operational costs

Decrease in the quantity of out of spec material in the launching and production steps.

Cooling a Paste

Cooling a Paste

Cooling a Paste

Cooling a Paste

Cooling a Paste

PAINTS

PAINTS

PAINTS

PAINTS

PAINTS

PAINTS

Suspension in a batch reactor

Suspension in a batch reactor

Suspension in a batch reactor

Suspension in a batch reactor

Suspension in a batch reactor

Non ideal stirring – non homogeneity

• VisiMix software is used in order to find the required stirring characteristics.

For example: The product XXXX is produced at a solid liquid reaction .

The main reaction at this process is:

BBCM + TA + POCA →XXXX

POCA reagent properties:

• Solid

• High particle size: mean=735 m m

• High density: 2300 kg/m 3

VisiMix was used for suspension calculation.

Scale up optimization using simulation experiments.

Scale Up Methodology

(J.M. Berty. CEP, 1979)

Scale up optimization using simulation experiments.

Scale Up Methodology

(J.M. Berty. CEP, 1979)

Scale Up optimization using simulation experiments.

In the three years since the commencement of this process, their engineers achieved a high level of proficiency in the use of the simulation models in order to analyze the results as a function of the process operational parameters.

After three years of working with this integrated plan – they have summarized their knowledge and experiences up to this point, as follows:

1. VisiMix products, when integrated in the validation process (up until they achieved a stable process and confirmed the production) – helped to reduce the number of lost production batches (each batch valued in millions of dollars) - from 100 to just under 10 batches – (review slide 25)

2. VisiMix program used in conjunction with another simulation tool - as reported in this presentation - contributed to the improvement of the teamwork style and professionalism. Net results were observed throughout the implementation of the new solution in better project development: EOR

(end of reaction) time reductions, projects development time and cost reduction, and in addition - increasing the expertise and qualification level of the professional staff.

The presentation can be review on the Visimix Website in the References -

Users Publications page. (

Scale up optimization using simulation experiments-Chemagis presentation )

Scale Up optimization using simulation experiments.

Financial aspects

# produced lots needed until till a stable process is achieved

Summary

• Save per project

• Save during development

Thank You

Positive reaction from customers from all over the world confirms:

- VisiMix is of tremendous help wherever mixing is involved .

Thank you

From the VisiMix Team

Thank you for your attention

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