Scientific research (testing)

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Treatment of animals
1. Treat animals humanly
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Scientific research (testing)
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10/15/2013 7:09:00 PM
Experimental Testing
10/15/2013 7:09:00 PM
 More than 100 million animals every year suffer and die in cruel chemical,
drug, food, and cosmetics tests as well as in biology lessons, medical
training exercises, and curiosity-driven medical experiments at
universities.
 Animal Testing 101
 http://www.peta.org/issues/animals-used-forexperimentation/animal-testing-101.aspx
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 Each of us can help save animals from suffering and death in experiments
by demanding that our alma maters stop experimenting on animals, by
buying cruelty-free products, by donating only to charities that don't
experiment on animals, by requesting alternatives to animal dissection
and by demanding the immediate implementation of humane, effective
non-animal tests by government agencies and corporations.
 Animal Testing 101
 http://www.peta.org/issues/animals-used-forexperimentation/animal-testing-101.aspx
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 Non-human animals cannot give informed consent
 http://animalrights.about.com/od/vivisection/a/VivisectionFAQ.htm
 Why It’s Wrong to Test on Animals? Vivisection and Animal Rights
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 regardless of how large the cages are or whether the animals are
anesthetized before they are cut open, vivisection is antithetical to animal
rights because animals have a right to be free from experimentation,
imprisonment, and killing.
 Why It’s Wrong to Test on Animals? Vivisection and Animal Rights
 http://animalrights.about.com/od/vivisection/a/VivisectionFAQ.htm
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 Just as unethical experimentation on a group of humans cannot be
justified by a benefit to humanity at large, the same holds true for animal
experimentation and to say that experimentation on non-human animals
is justified but experimentation on humans is not would be speciesist.
 Why It’s Wrong to Test on Animals? Vivisection and Animal Rights
 http://animalrights.about.com/od/vivisection/a/VivisectionFAQ.htm
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 92 percent of experimental drugs that are safe and effective in animals
fail in human clinical trials because they are too dangerous or don’t work.
 Labs that use mice, rats, birds, reptiles and amphibians are exempted
from the minimal protections under the Animal Welfare Act (AWA).
 According to the Humane Society, registration of a single pesticide
requires more than 50 experiments and the use of as many as 12, 000
animals
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 Several cosmetic tests commonly performed on mice, rats, rabbits, and
guinea pigs include:
 skin and eye irritation tests where chemicals are rubbed on shaved skin
or dripped into the eyes without any pain relief.
 repeated force-feeding studies that last weeks or months, to look for
signs of general illness or specific health hazards.
 widely condemned “lethal dose” tests, where animals are forced to
swallow large amounts of a test chemical to determine what dose causes
death.
 11 Facts about Animal Testing
 http://www.dosomething.org/tipsandtools/11-facts-about-animaltesting#
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 No law requires animal testing of cosmetics or personal care and
household cleaning products
 You may think companies that test on animals do so for your safety, but
these tests usually aren’t reliable in determining a chemicals effect on
humans.
 Reactions can vary greatly from species to species so it is quite difficult to
come to any conclusions about what a substance will do to humans by
testing it on a rabbit.
 product that made a test animal go blind could still be sold to you
 animal tests also tend to be more expensive than alternative methods
 What's Wrong With Testing on Animals?
 http://www.gan.ca/lifestyle/animal+testing/index.en.html
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 Studies in esteemed publications such as the Journal of the American
Medical Association and the British Medical Journal have repeatedly
concluded that because of the fundamental biological differences among
species, animal tests do not reliably predict outcomes in humans. These
same studies have also concluded that the overwhelming majority of
animal experiments fail to lead to medical advances that improve the
health of humans and, in fact, are often dangerously misleading.
 Pioneering contract research laboratory CeeTox uses human cellbased test tube toxicity screening to test drugs, chemicals,
cosmetics, and consumer products.
 biotechnology firm Hµrel has developed a 3-D in vitro (test tube)
human "liver" that scientists can use to study the breakdown of
chemicals in the human body.
 VaxDesign's groundbreaking Modular IMmune In Construct (MIMIC)
system uses human cells to create a working dime-sized human
immune system for testing the safety and effectiveness of
HIV/AIDS vaccines.
 The scientists and engineers at Harvard's Wyss Institute have
created "organs-on-a-chip," including the "lung-on-a-chip" and
"gut-on-a-chip." These tiny devices contain human cells in a 3dimensional system that mimics human organs.
o Alternatives to Animal Testing
o http://www.peta.org/issues/animals-used-forexperimentation/alternatives-to-animal-testing.aspx
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Experimental Testing
10/15/2013 7:09:00 PM
 From antibiotics to blood transfusions, from dialysis to organ
transplantation, from vaccinations to chemotherapy, bypass surgery and
joint replacement, practically every present-day protocol for the
prevention, treatment, cure and control of disease, pain and suffering is
based on knowledge attained through research with lab animals.'Foundation for Biomedical Research
 The House of Lords Select Committee, the Parliamentary Animal
Procedures Committee and the independent Nuffield Council on Bioethics
all concluded that testing on animals is a scientifically sound method, has
yielded great results in the past, and is crucial for future advances.
 Animals also have improved healthcare and a longer lifespan. Farm
animals, household pets, wild species and endangered species are all
benefiting from the research conducted through animals. There are
vaccines for rabies, distemper, tetanus, parvo virus and numerous other
illnesses in cats, dogs and countless other domesticated animals.
 Smallpox (cow): The vaccinia vaccine against smallpox was derived from
the cowpox virus used by Edward Jenner following his observation that
farm workers who contracted cowpox were protected against smallpox
 Polio has been eradicated from North America and people in countries all
over the world are being successfully treated (mouse and monkey).
 BENEFITS
 http://www.pro-test.org.uk/facts.php?lt=c
 But now, thanks in large part to animal-based research, there is a new
molecular and genetic understanding of tumor biology, leading to
treatments that set out to more directly kill cancer cells, which are
molecularly different from normal cells.
 Every three and a half minutes, a baby is born with a birth defect in the
United States. Studies with animals determined that folic acid, a B
vitamin, helps prevent serious birth defects of the brain and spinal cord
when taken before conception and early in pregnancy.
 research with animals has led todevelopment of anesthesia, antibiotics,
and insulin; use of cardiac pacemakers and heart bypass surgery;
surgical advancements for organ transplants, hip replacements, and
cataract surgery; and treatments for a host of diseases, including
diabetes, multiple sclerosis, AIDS, and children’s leukemia.
 http://www.amprogress.org/animal-research-benefits
 In human terms, research with animals has led to development of
anesthesia, antibiotics, and insulin; use of cardiac pacemakers and heart
bypass surgery; surgical advancements for organ transplants, hip
replacements, and cataract surgery; and treatments for a host of
diseases, including diabetes, multiple sclerosis, AIDS, and children’s
leukemia.
 Jon Klingborg, DVM, president of the California Veterinary Medical
Association (CVMA)
 http://www.cvma.net/doc.asp?ID=2403
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 People for the Ethical Treatment of Animas (PETA)
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 Foundation for Biomedical Research
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 DoSomething.org
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 Global Action Network (GAN)
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 Journal of the American Medical Association
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 British Medical Journal
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 CeeTox
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 Hurel
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 Harvard's Wyss Institute
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 Protest.org
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