Radiologic Events: Attack on a Nuclear Power Plant Radiological Events Objectives • Recognize the potential consequences of a terrorist attack on a nuclear power plant • Describe the different types of radiation particles and waves and their effect on the body Radiological Events Objectives • Differentiate between radiation exposure and contamination • Recognize the characteristic signs and symptoms of acute radiation syndrome • Learn to perform rapid assessment of nuclear/radiation events in a disaster situation Radiological Events Objectives • Learn specific antidotes and medical interventions for nuclear/radiation terrorism victims • Learn specific pre-hospital and hospital management strategies including proper notification of radiation disasters Radiological Events Case • Terrorists attack a nuclear power plant 30 miles outside a major metropolitan area by flying a high jacked jet liner into the plant. • The impact results in an explosion and fire. • Fire fighters and paramedics are called to the scene. Radiological Events Case • There are multiple casualties and several trauma victims are being transported to your health care facility. • The news media is questioning your health team regarding radiation exposure risks Radiological Events Nuclear Power Plant Disaster: Chernobyl, 1986 Radiological Events Attacks on Reactors • Radioisotopes released – Large quantities of radioiodines and radiocesiums – A large variety of other radioisotopes may be released in smaller quantities Radiological Events Attacks on Reactors • Which way is the wind blowing? – The radioactive cloud from the burning reactor will travel according to wind direction. Radiological Events Attacks on Reactors • Prevention – Individuals in the path of the radioactive cloud need to be evacuated Radiological Events Electromagnetic Radiation • Electromagnetic radiation includes a wide spectrum of radiation energy characterized by frequency and wave length. • Ionizing radiation has high frequency and short wave length Radiological Events Ionizing Radiation • Ionizing radiation includes both electromagnetic (X and gamma rays) and particulate radiation Radiological Events Particles • Alpha • Beta • Neutrons Radiological Events Alpha Particles • A helium nucleus • Unable to penetrate skin • Emitted from radioisotopes such a plutonium, uranium Radiological Events n n ++ Beta Particles • Able to penetrate skin • Negatively charged • Can produce skin superficial burns • Emitted by several radioisotopes (e.g. Cobalt 160) Radiological Events Neutron particles • Uncharged • Able to penetrate deeply • Hazard inside nuclear reactors Radiological Events Penetration Abilities of Different Types of Radiation Alpha Particles Stopped by a sheet of paper Radiation Source Beta Particles Stopped by a layer of clothing or less than an inch of a substance (e.g. plastic) Gamma Rays Stopped by inches to feet of concrete or less than an inch of lead Neutrons Stopped by a few feet of concrete X-Rays and Gamma Rays • Gamma and X radiation differ by source: gamma rays comes from the nucleus and X-rays come from the electron orbits • Because they don’t have mass or charge, they penetrate very deeply Radiological Events Detecting Radiation RADIATION CANNOT BE SEEN, HEARD, TASTED OR SMELLED But, it can be easily measured if you have the right equipment Radiological Events Radiation Detectors Alpha Survey Meter Radiological Events Beta and Gamma Survey Meter Radiation Dose Units Unit Value Rad (radiation absorbed dose) Rem (radiation equivalent-man) Gray (Gy) 0.01 J/kg Sievert (SV) 100 rem Radiological Events Bio damage from 0.01 J/kg 100 rad Contamination • Contact with radioactive material (radionuclides) that can be spread to other people / properties • Inhaled, ingested, transferred from surface to surface Radiological Events Exposure vs. Contamination External Exposure: external irradiation of the body with rays or particles absorbed dose Contamination: radioactive material (radionuclides) on patient (external) or within patient (internal). Radiological Events Adapted from CDC Bioterrorism Web site If the patient is externally contaminated with radionuclides, you can Decontaminate If radionuclides have gotten inside the body, consider chelation therapy Factors Determining Radiation Exposure • Time • Distance • Shielding Radiological Events Injuries Associated with Radiological Incidents • Acute Radiation Syndrome (ARS) • Localized radiation injuries/cutaneous radiation syndrome • Internal or external contamination • Combined radiation injuries with - Trauma - Burns • Fetal effects Radiological Events Acute Radiation Syndrome A Spectrum of Disease Radiological Events Phases of Acute Radiation Syndrome Exposure Prodromal Stage Latent Stage Manifest Illness Time (days to years) www.bt.cdc.gov/radiation/arsphysicianfactsheet.asp Radiological Events Recovery Stages of Acute Radiation Syndrome Stage 1: (50-150 rads) • No symptoms or minimal viral symptoms for up to 48 hours • Spontaneous recovery usually occurs • Sterility is a risk Radiological Events Stages of Acute Radiation Syndrome • • • • Stage 2: The Hematopoetic Syndrome (150400 rads) Whole body exposure Bone marrow suppression occurs with loss of WBC and platelets Infection and bleeding problems occur LD 50 250-400 rads Radiological Events Stages of Acute Radiation Syndrome Stage 3: Severe Hematopoetic Syndrome (150-400 rads) • Life saving bone marrow transplantation needed • Care rationing during MCI will lower LD50 Radiological Events Absolute Lymphocyte Count • Measure every 4 - 6 hours initial 48 hours • Normal: approx 2500 cells/ml • > 1200: probably non-lethal • 300 to 1200 cells/ml: significant (hospitalize) • < 300 cells/ml: critical Radiological Events Andrews Curve 1: 2: 3: 4: 1 Gy 4 Gy 6 Gy 7.1 Gy Radiological Events Stages of Acute Radiation Syndrome Stage 4: The Gastrointestinal Syndrome (150-400 rads) • GI lining cells die • Severe diarrhea and electrolyte losses • Life saving fluid and electrolyte replacement Radiological Events Stages of Acute Radiation Syndrome Stage 5: The CNS Syndrome (>1500 rads) • Confusion, ataxia, and sensory deficits • Death within 48 hrs regardless of treatment • Early appearance of CNS symptoms is an ominous sign Radiological Events Pre-Hospital Management • Evacuation of persons who are in the path of a radiation cloud is the most effective pre-hospital measure – this action is the responsibility of public health authorities • Need effective communication with residents as to steps they can take to reduce exposure Radiological Events Patient Management - Priorities • Initial triage and decontamination are ideally done outside the hospital (have a plan in place) to avoid contamination of the ED • Patients exposed only to external EM radiation (e.g. x-ray or gamma rays) are not radioactive; patients exposed to particulate radiation will be radioactive • Standard medical triage is the highest priority • Radiation exposure and contamination are secondary considerations Radiological Events Patient Management - Protocol Based on: • Injuries • Signs and symptoms • Patient history • Contamination survey Radiological Events Hospital Management • Security • Radiation Safety Officers/dosimeters, GM • 24-hour hotline (217) 785-0600 • Radiation Duty Officer @ Illinois Department of Nuclear Safety • Waste disposal • Labeled, plastic bags Radiological Events Management • Contaminated patient – immediately isolated until monitored & decontaminated • Monitor EMS and ambulance • ABC’s • Cover all wounds • Radiation burns are like sun burns Radiological Events External Contamination • Radioactive material (usually in the form of dust particles) on the body surface and/or clothing • Radiation dose rate from contamination is usually low, but while it remains on the patient it will continue to expose the patient and staff Radiological Events Patient Decontamination • Remove and bag the patient’s clothing and personal belongings (this typically removes 80 - 90% of contamination) • Handle foreign objects with care until proven non-radioactive with survey meter • Survey patient and collect samples - Survey face, hands and feet - Survey rest of body Radiological Events Protecting Staff from Contamination • Use standard precautions • Survey hands and clothing frequently • Replace contaminated gloves or clothing • Keep the work area free of contamination Radiological Events Examples of Radiation Skin Burns Radiological Events Decontamination of Skin • Use multiple gentle efforts • Use soap & water • Cut hair if necessary (do not shave) • Promote sweating • Use survey meter Radiological Events Cease Patient Decontamination • When decontamination efforts produce no significant reduction in contamination • When the level of radiation of the contaminated area is less than twice background • Before intact skin becomes abraded Consider internal contamination Radiological Events Decontamination of Wounds • Contaminated wounds: – Irrigate and gently scrub with surgical sponge – Debride surgically only as needed • Contaminated thermal burns: – Gently rinse – Changing dressings will remove additional contamination Radiological Events Specific Therapy Radionuclide Therapeutic Approach Tritium Dilution (force fluids) Iodine-125 or I-131 KI, or SSKI Cesium-134 or cesium- 137 Prussian blue Strontium-89, or 90 Decrease abs (antacids), blockage (strontium lactate), displacement (oral phosphate), mobilization (ammonium chloride) Plutonium Zinc or calcium (DTPA) Radiological Events Radioiodines and Thyroid Cancer Radioiodines concentrate In the thyroid gland and can increase the risk of thyroid cancer Radiological Events You can reduce the radioiodine thyroid dose by giving potassium iodide • Potassium Iodide (KI) considerations • Who should get KI? • Useful at the beginning of an exposure • Only protects against thyroid cancer Radiological Events Dosage (KI) Age Group Infants < 1 month Dosage 16 mg Children 1 month – 3 yrs 32 mg Children 3–18 yrs 65 mg Adults 130 mg Radiological Events Key Points • Ionizing radiation includes: – Electromagnetic radiation: X and gamma – Particulate radiation: alpha, beta, neutrons Radiological Events Key Points • Patient can be: – Irradiated externally – Contaminated with radionuclides • Which patients are radioactive? – Those contaminated with radionuclides – These patients need to be decontaminated – Some internally deposited radionuclides can be removed with chelation therapy Radiological Events Key Points • Protect yourself from radiation: – Reduce the time of exposure – Increase the distance from the radiation source – Apply shielding between yourself and the radiation source Radiological Events Key Points • Acute Radiation Syndrome: – Stages progress from hematopoetic to gastrointestinal to central nervous system with increasing dose – The absolute lymphocyte count is the best predictor of dose • Long-term consequences – Increase in cancer, especially thyroid cancer – With radioiodine exposure, thyroid dose can be reduced by using KI Radiological Events Key Points • Have a radiation disaster management plan in place for your hospital • Be prepared for psychological consequences Radiological Events Resources • CDC Bioterrorism – www.bt.cdc.gov • Radiation Emergency Assistance Center & Training Site (REAC/TS) http://www.orau.gov/reacts/default.htm • Medical management of radiological casualties handbook www.afrri.usuhs.mil Radiological Events This completes the current presentation. Radiological Events