Genetics History • Genetics is the study of genes. • Inheritance is how traits/characteristics, are passed on from generation to generation. • Genes are passed parents offspring; – get one allele for each gene from each parent during Meiosis cell division • Chromosomes are made up of genes – Alleles=diff. versions of a gene • Gene is made up of DNA. • Gregor Mendel is considered “The Father of Genetics“…Used Pea Plants to discover inheritance. Mendel Breeding Experiment P generation (parental generation) F1 generation the hybrid offspring. Allowing these F1 hybrids to self-pollinate produces: F2 generation (second filial generation). Mendel’s analysis of this that lead to an understanding of genetic crosses. Mendelian Genetics • Dominant traits- traits that are expressed. • Recessive traits- traits that are covered up. • Genotype- the types of genes (Alleles) present. • Phenotype- what it looks like. • Homozygous- two of the same alleles. • Heterozygous- two different alleles. How do Alleles differ? Dominant allele Recessive allele Recessive allele Recessive allele Dominant - a term applied to the trait (allele) that is expressed irregardless of the second allele. Usually indicated with a Capital Letter (ex. A, L, P) Recessive - a term applied to a trait that is only expressed when the second allele is the same (Usually indicated with a lower-case letter (ex. a, l, p) Probability and Punnett Squares Punnett square: diagram showing the probabilities of the possible outcomes of a genetic cross Genotype versus phenotype. How does a genotype ratio differ from the phenotype ratio? Punnett squares - probability diagram illustrating the possible offspring of a mating. Ss X Ss gametes How Does it Work? Pedigree analysis reveals patterns in human inheritance In these family trees, sqaures=male, circles= females. A horizontal line connecting a male and female (--) indicates a mating, with offspring listed below in their order of birth, from left to right. Shaded symbols stand for individuals with the trait being traced. Incomplete Dominance • Every genotype has its own phenotype. – (One allele not completely dominant over the other.) • Third phenotype that is a blending of the parental traits. – (2 alleles produce 3 phenotypes.) • Result: Heterozygous phenotype somewhere inbetween homozygous phenotype. Incomplete Dominance Examples: • Trait: Flower Color Expressions: Red x White Pink RR= Red; RW= pink; WW= white • straight hair x curly wavy 2. Codominance • Both alleles contribute to the phenotype. • In codominance, neither allele are dominant; both are expressed. – Example: In some chickens Black Chicken x White Chicken Speckled Chicken YOU tell me which type of dominance…Incomplete or Codominace? Codominance! Type of Dominance? Incomplete Dominance! Type of Dominance? Incomplete Dominance!