LymeTestingUK
In Conjunction With
The Center for Bio-Individualized Medicine
LymeTestingUK.com
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Agenda
 Lyme Disease- Cause and Symptoms
 Who Should Be Checked for Lyme Disease
 Routes of Infection
 A Primer on Lyme Disease Testing
 Why We Use MDL Labs in USA
 How We Compare With Other Labs in Service and Pricing
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Our Passion
To See That Suffering from Chronic Illness is
Eradicated
Lyme and it’s Co-Infections are the leading
cause of suffering in the world today
We are making the testing for Lyme disease
and all associated infections:
Accurate
Unbiased and
Affordable
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Lyme Disease
CAUSE & SYMPTOMS
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Lyme Disease
 Lyme disease is a bacterial infection that is spread
through the bite of one of several types of ticks.
 Lyme disease (Lyme borreliosis) is an infectious disease caused
by at least three species of bacteria belonging to the genus
Borrelia. Borrelia burgdorferi is the main cause of Lyme disease
in North America, whereas Borrelia afzelii and Borrelia
garinii cause most European cases.
 Texas (being Texas) had to have it’s own strain….hence Borellia
Lonestari….The Lonestar Tick

Wikipedia
(c) Dr. Jess P. Armine 2015
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Risk Areas
(c) Dr. Jess P. Armine 2015
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Lyme is EVERYWHERE!
 Incredible But True! Lyme Disease is in over 80 Countries!
 The Subantarctic is a region in the southern hemisphere just north
of the Antarctic Circle which contains the Campbell Islands and îles
Crozet. According to the "Encyclopedia of the Antarctic Vol.1" (ed: B.
Riffenburg, 2007 p.335), "The zoonosis Lyme disease is caused by
the spirochaete Borrelia burgdorferi, which is carried by sea birds
transmitted by Ixodes ticks. It has been found through DNA analysis
in ticks on the Campbell Islands and the îles Crozet. King penguins
on the îles Crozet have antibodies to B. burgdorferi.“

http://www.lymediseaseassociation.org/index.php/about-lyme/cases-stats-maps-a-graphs/940lyme-in-more-than-80-countries-worldwide
(c) Dr. Jess P. Armine 2015
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WHO SHOULD BE CHECKED
FOR LYME DISEASE ?
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The Answer is Quite Simple
 As you'll see, Lyme
disease can manifest in
about 1000 different
ways. Often, "diagnoses"
like chronic fatigue
syndrome, chronic pain
syndromes, autoimmune
diseases, ADD, OCD,
fibromyalgia, and many
others have Lyme disease
are one of the coinfections as their root.
 The answer to this
question is simply this:
 If you, a loved one, or a
friend (or even an
acquaintance) has been
diagnosed with a
syndrome that is
responding poorly or not
at all to standardized
treatment Lyme disease
or one of the co-infections
may be the untreated
cause of that syndrome.
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Common Symptoms…Perhaps
Common Causation?
Symptom
Chronic Lyme
Fibromyalgia
ME/CFS
Dysautonomia
Fatigue
X
X
X
X
Chronic Pain
X
X
X
X
Mood Changes
X
X
X
X
Confusion/
X
X
X
X
Numbness Tingling
X
X
X
X
Sensitivity to light
X
X
X
X
Inflammation
X
X
X
X
Brain Fog
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Recalcitrant Chronic Illnesses
IS IT LYME OR CAN IT BE
OTHER MICROBES?
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Vectorbourne Diseases
Borellia Burgdorferi
 Borellia
 Garinii
 Afzelli
 Lonestari
Co-Infections
 Bartonella
 Babesia
 Anaplasma
 Ehrlichia
 Rickettsia
LymetestingUK.com checks for all these via several modalities
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LymetestingUK.com
Includes at no extra cost
Tests for:
 Candida Albicans (Yeast)
 Toxoplasmosis (brain
parasite)
 Parvovirus
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Chronic Illness
Can be caused by
all the microbes
we test for
singularly or in
combination.
So, why test just
for Lyme?
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ROUTES OF INFECTION
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Routes of Infection
 Tick bite (Myth: the tick has to be attached for 36- 48 hrs. before it
can transmit the microorganism…some studies are showing as
little as 30 min…when in doubt, check it out!)
 From infected parents, breastfeeding from infected parent (Hotly
debated) http://www.lymedisease.org/resources/children.html
 Blood transfusion or receiving blood from other parasitic insects
 New evidence that there can be sexual transmission http://afmr.org/Western
(c) Dr. Jess P. Armine 2015
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Ticks
(c) Dr. Jess P. Armine 2015
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When In Doubt…Check It Out!
If you find an embedded Tick
and you remove it…take it to
the doctor. The tick can be
submitted to the lab to test for
Lyme.
(c) Dr. Jess P. Armine 2015
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(c) Dr. Jess P. Armine 2015
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What to Look for…The “Bulls Eye Rash”
But this rash DOESN’T always happen and the presence or history of this rash
SHOULD NOT BE USED AS AN EXCLUSION CRITERIA!
(c) Dr. Jess P. Armine 2015
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The Lyme Organism is a Spirochete
(c) Dr. Jess P. Armine 2015
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Symptoms
Numerous and Varied
 Because the bacteria spreads through the blood to tissue,
joints, bone marrow, organs and the brain (CNS), the
symptoms are both numerous and varied. They can
include:
(c) Dr. Jess P. Armine 2015
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(c) Dr. Jess P. Armine 2015
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Children's Symptoms
Lyme pediatric specialist Charles Ray Jones, MD, compiled a
list of common symptoms of infection in his young patients:
severe fatigue unrelieved by rest
insomnia
headaches
nausea, abdominal pain
impaired concentration
poor short-term memory
inability to sustain attention
difficulty thinking and expressing thoughts
difficulty reading and writing
being overwhelmed by schoolwork
difficulty making decisions
confusion
uncharacteristic behavior
outbursts and mood swings
fevers/chills
joint pain
dizziness
noise and light sensitivity
Dr. Jones has also documented
congenital, or gestational, Lyme disease
in some children who were infected in
utero or by breastfeeding. In these
patients his suspicion is raised when
the child has:
•frequent fevers
•increased incidence of ear and throat
infections
•increased incidence of pneumonia
•irritability
•joint and body pain
•poor muscle tone
•gastroesophageal reflux
•small windpipe (tracheomalacia)
•cataracts and other eye problems
•developmental delay
•learning disabilities
•psychiatric problems
http://www.lymedisease.org/resources/children.html
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(c) Dr. Jess P. Armine 2015
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February 20, 2014 newspaper article
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A Primer On
LYME DISEASE TESTING
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Testing...Here Thar Be Dragons Matey!
 ELISA (Enzyme Linked Immuno-Sorbent Assay) (Ig, IgG)
 Western (immunoblot)Blot ( to separate and identify proteins. In this
technique a mixture of proteins is separated based on molecular weight, and thus by type,
through gel electrophoresis. These results are then transferred to a membrane producing a
band for each protein. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3456489/)
 Polymerase chain reaction (PCR) (multiplies DNA)
 Lyme Culture Blood Test™ Advanced Laboratory Services, Inc.
 Indirect findings on other lab tests
(c) Dr. Jess P. Armine 2015
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Problems: False Positives and False
Negatives
 The most common tests measure the patient’s antibody response to
infection (ELISA). When your body is invaded by the Lyme
spirochetes, your immune system makes antibodies to fight the
infection. Tests that measure antibody levels are indirect tests
because they measure the body’s response to infection rather than
the presence of the bacteria themselves.
 During the first 4-6 weeks after exposure, most people have not
developed the antibody response that the test measures.
 Doctors commonly order an ELISA first to screen for the disease
and then confirm the disease with a western blot. However, current
ELISA tests are not sensitive enough for screening and may miss
over half the true cases.
 Because of this, the best antibody test to use for diagnosis is the
western blot (immunoblot).
(c) Dr. Jess P. Armine 2015
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Western Blot (Immunoblot)
 The read-out from the western blot looks like a bar code.
The pattern produced by running the test with your
blood is compared to a template pattern that represents
known cases of Lyme disease. If your blot has bands in
the right places, and the right number of bands, it is
positive. Some of the bands are more significant than
others.
 Different criteria from different sources are used to
determine the presence of Lyme.
(c) Dr. Jess P. Armine 2015
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(c) Dr. Jess P. Armine 2015
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PCR
Polymerase chain reaction (PCR)
multiplies a key portion of DNA from the
Lyme bacteria so that it can be detected.
While PCR is highly accurate when the
Lyme DNA is detected, it produces many
false negatives. This is because Lyme
bacteria are sparse and may not be in the
sample tested.
(c) Dr. Jess P. Armine 2015
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Why MDL Labs
One of the finest and most accurate labs in the US
 Certified by:
 New Jersey State Department of
Health
 Pennsylvania Department of
Health
 Florida Clinical Laboratory State
 New York State Department of
Health
 Rhode Island Department of
Health
 California Department of Health
 Maryland Department of Health
 CLIA
 Medicare
 CAP –
 Some Lyme Publications:




http://www.mdlab.com/company/certifications-licenses/
http://www.mdlab.com/company/research-development/

Meer-Scherrer L, Adelson ME, Mordechai E,
Tilton RC. 2006. Neuroborreliosis
associated with Alzheimer’s disease. Curr
Microbiol, 52(4):330-2.
Drisko J, Bischoff B, Giles C, Adelson ME,
Rao RV, McCallum R. 2005. Evaluation of 5
probiotic products for bacteria by DNA
extraction and PCR analysis. Dig Dis Sci,
50(6):1113-7.
Adelson ME, Feola M, Trama JP, Tilton RC,
Mordechai E. 2005. Simultaneous detection
of herpes simplex virus types 1 and 2 by
Real-Time PCR and Pyrosequencing. J Clin
Virol, 33(1):25-34.
Adelson ME, Rao RV, Tilton RC, Cabets K,
Eskow E, Fein L, Occi JL, Mordechai E.
2004. Prevalence of Borrelia burgdorferi,
Bartonella species, Babesia microti, and
Anaplasma phagocytophila in Ixodes
scapularis collected in northern New Jersey.
J Clin Microbiol, 42:2799-2801.
Meer-Scherrer L, Adelson ME, Mordechai E,
Lottaz B,
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MDL is the ONLY lab that allows
The Clinican ToVisualize the Immunoblot
IgG
Reports 1 when
I see 7 bands
Reports zero when
I see 3 bands
With Human Eyes, the test meets CDC criteria
Proper Interpretation = Less False Negatives
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Hong Kong: 27 year old female
with recalcitrant anxiety
IGG
IGM
The associated
Neurotransmitter Test
showing extreme
excitation (anxiety)
(c) Dr. Jess P. Armine 2015
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PCR
Polymerase chain reaction (PCR)
multiplies a key portion of DNA from the
Lyme bacteria so that it can be detected.
While PCR is highly accurate when the
Lyme DNA is detected, it produces many
false negatives. This is because Lyme
bacteria are sparse and may not be in the
sample tested.
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How to Diagnose Lyme?
 History, history, history
 Clinical findings
 Results of testing
 Rely on the preponderance of evidence…Not Just The TESTS!
The diagnosis of Lyme is a CLINICAL DIAGNOSIS!!!
 LymeTestingUK.com includes a person-to-person, unbiased
consultation with the healthcare provider for the purpose of
explaining the testing and sitting you on the right road. At
other labs, this is available at extra cost.
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What LymeTestingUK Offers
Complete,
Accurate Testing
for:
 Lyme Disease. Borellia
Burgdorferi (Immunoblot, PCR,
C6 Peptide)
 Co-Infections (Babesia,
Bartonella, Rikettesia, Ehrlichia,
Anaplasma)
 A Common Brain Parasite
(Toxoplasmosis)
 Yeast (Candida Albicans)
 Parvovirus
 Mycoplasma
We Check for ALL
forms of Lyme
Disease:
Borellia lonestari by RealTime PCR
Borellia garinii by Real-Time
PCR
Borellia afzelii by Real-Time
PCR
Babesia WA1 by Real-Time
PCR
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LymeTestingUK.com Includes
 An Unbiased, Interpretive
Consultation with A
Health Care Provider*
 Door to Door Shipping
 No hidden or extra costs
* The Health Care Provider will interpret your
tests results to help you decide on your future
course of action. Please note, purchasing this test
does not make you one of our registered patients
and so we cannot offer treatment just guide you
in choosing your options.
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Why Such Extensive Testing?
Because Chronic Illnesses May Be Caused By Numerous
Microorganisms…not Just Borellia Burgdorferi
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LymetestingUK.com?
Igenex?
InfectoLab?
Armin Labs?
HOW DO WE COMPARE?
41
Test
Babesia PCR
Lyme Testing UK
Price £
INCLUDED
Infectolab
Price £
217
ARMIN LAB
Price £
99.02
IGENEX
Price £
INCLUDED
Babesia IGG
Babesia IGM
INCLUDED
INCLUDED
127
51.24
51.24
INCLUDED
Bartonella henselae PCR
Bartonella IGG/IGM
INCLUDED
217
153
99.02
102.48
INCLUDED
B. burgdorferi (Lyme) PCR
INCLUDED
198
84.17
INCLUDED
Ehrlichia PCR
INCLUDED
217
99.02
NOT INCLUDED
Ehrlichia IGG/IGM
INCLUDED
197
51.24
NOT INCLUDED
Western Blot Lyme
(IMMUNOBLOT)
Lyme IGG/IGM
INCLUDED
156
79.20
INCLUDED
INCLUDED
197
Mycoplasma
INCLUDED
179
34.65
NOT INCLUDED
Lyme Disease C6 peptide by ELISA
Borellia lonestari by Real-Time PCR
INCLUDED
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
NOT INCLUDED
Borellia garinii by Real-Time PCR
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
Borellia afzelii by Real-Time PCR
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
Babesia WA1 by Real-Time PCR
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
Anaplasma phagocytophilum IgG/IgM by IFA
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
Anaplasma phagocytophilum PCR
INCLUDED
NOT AVAILABLE
NOT AVAILABLE
NOT INCLUDED
Rickettsia rickettsii (RMSF) by Real-Time PCR
INCLUDED
151
84.17
NOT INCLUDED
Candida albicans by Real Time PCR
INCLUDED
NOT AVAILABLE
34.65
NOT INCLUDED
Toxoplasma gondii by Real Time PCR
INCLUDED
NOT AVAILABLE
34.25
NOT INCLUDED
Expert Consultation
INCLUDED
NOT INCLUDED
AT EXTRA COST
NOT INCLUDED
Shipping
INCLUDED
36.93
NOT INCLUDED
Use of Credit Card
INCLUDED
£699.00
+2.95%
£969.45
£862.00
£2009.00
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Other Labs
Do Minimal Testing
Charge for Shipping
Health Care Provider
Consultation is at
Extra Cost
LymeTestingUK.com
All Inclusive Price
No Hidden Costs
Extensive Testing
Less Costly
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LymeTestingUK
Pricing
 For Nearest Equivalent
Tests:
 IgeneX
 LymeTestingUK.com:
£ 699.00!!
 £ 969.45
 Armin Labs:
 £ 862.00
 All Inclusive…No
Hidden or Extra Costs
 InfectoLab:
 £ 2009.00
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