Review • Mitosis is cell division that occurs in somatic cells – all cells of the body EXCEPT the sex cells. Mitosis • In mitosis, two daughter cells are produced that are GENETICALLY IDENTICAL to the parent cell Mitosis • Somatic cells contain all of the chromosomes for that particular animal. Mitosis • This is represented as 2n or diploid • In humans, there are 23 pairs of chromosomes for a total of 46 chromosomes. (2n=46 for humans) Mitosis • Somatic cells contain pairs of chromosomes with similar genetic information. Mitosis • One chromosome came from the mother, the other from the father. For Example: • Homologous chromosomes determine eye color. The one from mom is for brown eyes, the one from dad is for blue eyes. So… • Why do sex cells not go through mitosis to produce two daughter cells? Gametes • Sex cells, also known as gametes, are ova (female) and sperm (male) So….. • What would happen if sex cells each had a full set of chromosomes then egg and sperm united? So…. • The new individual created would have double the number of chromosomes. • Not a viable being Meiosis • The process of meiosis ensures that the correct number of chromosomes is maintained. Meiosis • Meiosis – The process that forms sex cells called gametes (ova and sperm cells) Meiosis • IT DOES NOT PRODUCE TWO NEW GENETICALLY IDENTICAL CELLS! Meiosis • Cells produced by meiosis only have half (1/2) the usual number of chromosomes that other cells have. Meiosis • This is represented as n and is said to be haploid. • What is the haploid number for humans? So How Are We All Different? • The process of meiosis also allows for genetic variation – we are not exact copies of our parents. Meiosis • Because of meiosis, the offspring has a combination of genetic material from each parent. Cats Cats • Cats have 38 chromosomes. • What is the haploid number? • What is the diploid number? Cats • How many chromosomes would a father cat’s sperm cells have? Cats • How many chromosomes would a skin cell on a cat have? Meiosis • Meiosis goes through 2 complete cycles in order to produce 4 cells that each have ½ the number of chromosomes (haploid) Meiosis I - Interphase • Interphase – DNA is replicated Meiosis I – Prophase I • Just like in mitosis, the chromatin shortens and thickens into chromosomes. In meiosis, homologous chromosomes pair up to form tetrads. Meiosis I • A tetrad is 4 chromatids. Meiosis I • While lined up closely together, homologous chromosomes may “cross over” Meiosis I • Crossing over – A piece of DNA from one homologous chromosome changes places with the SAME SECTION of DNA on the other homologous chromosome Meiosis I • This is what allows for genetic variation! Meiosis I – Prophase I • Nuclear membrane disintegrates and spindle forms Meiosis I – Metaphase I • Homologous pairs of chromosomes line up at the equator Meiosis I – Anaphase I • Homologues (homologous chromosomes) are pulled apart. • There is now a different mix of homologues at each pole. Meiosis I – Telophase I • New nuclear membranes form around each pole. • Each of the two new cells has one chromosome out of each pair of chromosomes Meiosis II – Interphase II • Just a growth time • THERE IS NO DUPLICATION OF DNA!!!! Meiosis II – Prophase II • Nuclear membrane breaks down and new spindle forms Meiosis II – Metaphase II • Chromosomes line up in the middle Meiosis II – Anaphase II • Chromosomes are pulled apart – divides the chromosomes into chromatids. Meiosis II – Telophase II • New nuclear membranes form around all 4 new cells http://highered.mcgrawhill.com/olcweb/cgi/pluginpop.cgi?it=swf::535: :535::/sites/dl/free/0072437316/120074/bio1 9.swf::Stages%20of%20Meiosis