LAB 7 THE CARDIOVASCULAR SYSTEM BY-102 Zach Nolen Types of Systems • Open System • Insects and crustaceans have this system • Closed System • We have this system Closed Circulatory System • There are 3 things needed for a closed system: • Pump = Heart • Pipes = Blood Vessels • Medium = Blood Components of Blood • Our blood is composed of several components • 55% Plasma • 45% formed elements • Red Blood Cells (RBCs) - Erythrocytes • White Blood Cells (WBCs) – Leukocytes • Platelets - Thrombocytes Red Blood Cells • Are biconcave with no nucleus • Contain hemoglobin to transport oxygen • Transport oxygen and carbon dioxide White Blood Cells • Part of the immune system • Help fight off foreign invaders • Cause immune responses such as allergies, fever, and inflammation Platelets • Responsible for clotting • Release fibrin which causes RBCs to club together to form a scab • Hemophilia is a hereditary blood disease where blood can’t clot properly. • Can also be caused by a Vitamin K deficiency Circulation of Blood Double Circulation • Composed of 2 parts: • Pulmonary Circulation • RBCs pick up oxygen and drop off carbon dioxide • Systemic Circulation • RBCs deliver oxygen to cells and pick up carbon dioxide Veins and Arteries • In all types of circulation • Veins carry blood TO the heart • Arteries carry blood AWAY FROM the heart • Blood vessels start out large leaving the heart, get smaller, then get bigger coming back to the heart Arteries → Arterioles → Capillaries (oxygen exchange) → Venules →Veins Major Blood Vessels • There are four major sets of vessels that attach to the heart • Superior and Inferior Vena Cava – Right Atrium • Right and Left Pulmonary Arteries – Right Ventricle • Right and Left Pulmonary Veins – Left Atrium • Aorta – Left Ventricle The Heart Blood Flow through the Heart Pulmonary Left Atrium Veins Left Ventricle *Lungs* Pulmonary Arteries Aorta Right Ventricle *Body* Right Atrium Inferior Vena Cava Superior Vena Cava Heart Valves • Atrioventricular Valves • Tricuspid – between the right atrium and right ventricle • Bicuspid (Mitral valve) – between the left atrium and left ventricle • Semilunar Valves • Pulmonary Valve – between the right ventricle and the pulmonary arteries • Aortic Valve – between the left ventricle and the aorta Heart Murmur • Caused by a valve not shutting all the way when the way when the heart beats or a hole in the heart • Causes blood to backflow in the opposite direction of intended path Atherosclerosis • Build up of fat in the blood vessels • Can block blood from flowing (increasing blood pressure) • Can rip or tear blood vessel (causing a stroke) Heart Sounds (“Lubb-Dubb”) • First Sound: “Lubb” • Corresponds to the closing of the atrioventricular valves • Semilunar Valves open at this time • This is the start of systole (contraction phase) • Second Sound: “Dubb” • Corresponds to the closing of the semilunar valves • Atrioventricular valves open at this time • This is the start of distole (relaxation phase) Blood Pressure • Is recorded like a fraction • 120/80 • The top number is the systolic pressure and the bottom number is the diastolic pressure Systolic/Diastolic • Systole • Moment blood leaves the heart • Contraction of ventricles • Moment of highest pressure in the blood vessels • Diastole • Moment of rest between heartbeats • Moment of lowest pressure in blood vessels How to determine these values • Korotkoff sounds • Sounds produced as blood spurts through a partially collapsed artery while taking blood pressure • First sound = Systolic (highest pressure) • Last sound = Diastolic (lowest pressure) Review Questions 1. What are the main components of human blood? 2. What are the three things needed for a closed circulatory system? 3. What is atherosclerosis? 4. What do platelets do? 5. What do red blood cells do? Lab Exercises • We will be completing the following exercises • Exercise C – p.71 • Exercise D – p.72 • You should complete all tables, graphs, and questions throughout the lab section. Before you leave • Clean up your work station Before next lab • Complete all sections for lab manual check • Complete study guide 2 (optional) • Study for test