Connect!
• Do you know of anyone who has to take
thyroid medicine?
• Why?
• What causes gigantism?
• Do you know of anyone who is a diabetic?
• What causes it?
Endocrine System
•is similar to the nervous
system because it sends
messages from one part of
the body to another
•unlike nerve control,
endocrine (chemical) control
is achieved through sending
hormones usually through
the circulatory system
Chunkin’ Time!
•How is the endocrine system similar to the nervous system?
•How is the endocrine system different from the nervous system?
•How do hormones get to where they are needed?
•Name some endocrine glands.
•protein hormones work by binding to receptor
molecules in the cell membranes of target cells
• once a protein hormone binds to the receptor, a
message is sent to the nucleus of the target cell,
causing it to take some action
Lock and Key Model
•different hormones have different shapes and
will only bind to the correspondingly shaped
receptor molecules on/in target cells
Steroid hormones
act a bit
differently…
see if you can
figure out the
difference!
Chunkin’ Time!
• What is the name of the chemical site the hormone binds to?
• What is the cell called that the hormone acts on?
• Where are the receptors for protein hormones?
• How does a protein hormone get the cell to respond?
• How does a hormone “recognize” a target cell?
• Why is hormone recognition called the “Lock and Key Model”?
• How do steroid hormones work differently than protein?
• What kind of hormone has a receptor in
the cell membrane?
• Another example is ADH (AntiDiuretic Hormone) which is
released into the blood by the pituitary gland. It binds to
receptors in the kidney cells telling them to keep more
water, thus releasing less water in the urine.
Other hormones:
•
•
•
•
•
•
Insulin…from the pancreas
Thyroxin…from the thyroid gland
Growth…from the pituitary gland
Testosterone…from the testes
Estrogen…from the ovaries
Progesterone…from the ovaries
Note
•Regulation is achieved by both the nervous and
endocrine systems working together. These systems
show similarities and differences.
Differences
Similarities
nerve responses are more
rapid than endocrine
responses
both secrete chemicals
nerve responses are of
shorter duration than
endocrine responses
both play a major role in
homeostasis
both work by shape
Chunkin’ Time!
• What is the source, target, and job of ADH?
• Name 3 other hormones and their sources.
• What does regulation mean?
• What 2 systems work to regulate the body to maintain homeostasis?
• Give 3 similarities of the two systems.
• Give 2 differences between the 2 systems.
• What do these puzzle pieces have to do with the endocrine and
nervous systems?
• Explain this
diagram in
terms of
homeostasis.
Another “Just Couldn’t Resist!”…