GWSS/PSYCH 357 FINAL EXAM REVIEW Contraception Unwanted Pregnancy Pregnancy & Childbirth Menopause Review 10 10 10 10 10 20 20 20 20 20 30 30 30 30 30 40 40 40 40 40 50 50 50 50 50 Contraception – 10 Points QUESTION: What are the contraceptive actions of copper in an IUD? ANSWER: • • • • increases inflammatory reaction to the IUD decreases sperm viability slows ovum transport interferes with the actions of estrogen on the endometriumprevents build up. Contraception – 20 Points QUESTION: What are the five actions of progestin in contraceptives? ANSWER: 1. prevents ovulation by inhibiting LH and FSH production in the anterior pituitary 2. stimulates the production of a thick, pasty cervical mucus. 3. inhibits capacitation of sperm 4. slows the rate of ovum transport through the oviduct 5. prevents adequate build-up of the endometrium such that implantation is unlikely. Contraception – 30 Points QUESTION: How does Plan B/Next Choice work? If a fertilized ovum has already implanted, will Plan B/Next Choice work? ANSWER: Plan B/Next Choice works by: • preventing ovulation • slowing the rate of ovum or sperm transport • reducing endometrial buildup, making the endometrium unsuitable for implantation NO. Plan B/Next Choice only works before implantation Contraception – 40 Points QUESTION: What are the advantages and disadvantages of hormonal contraceptives? ANSWER: Advantages • may reduce the risk of ovarian cancer during and after use • decreased risk of endometrial and colorectal cancer during use • non-intrusive; it doesn’t interrupt sex • easy to use • highly effective • reduction of menstrual blood loss • reduced dysmenorrhea Disadvantages • no protection from STDs • may cause irregular menses or amenorrhea [particularly progestin-only contraceptives] • reduced estrogen levels may reduce bone density Contraception – 50 Points QUESTION: What are the advantages and disadvantages of IUD’s? ANSWER: Advantages: • 95-99% effective • non-intrusive (in sex behavior) • Long term effectiveness • Reduced dysmenorrhea with Mirena and Skylar • Reduced menstrual blood loss with Mirena and Skylar Disadvantages: • danger of uterine perforation on insertion and removal • increased menstrual blood loss with ParaGard • increased dysmenorrhea with ParaGard • Increased risk of PID, which can lead to infertility • May increase risk of vaginal infections • No protection from STDs • May increase susceptibility to STDs during first 3 months • Inflammation may increase risk of infertility Unwanted Pregnancy – 10 Points QUESTION: How are psychological reactions different for abortions for medical or eugenic reasons? ANSWER: • Medical (health of mother) - often followed by guilt • Eugenic (health/ development problems with fetus) - often followed by depression Unwanted Pregnancy – 20 Points QUESTION: What happens during a medical abortion? What are the effects of the medications administered? ANSWER: • Mefepristone (RU 486) & Misoprostol (prostaglandin) are administered in pill form. • Mefepristone results in the deterioration of the endometrium and Misoprostol causes contractions of the uterus to expel contents. • Patient must agree to have a surgical abortion if the medical abortion is not effective (only 92-99% effective). Unwanted Pregnancy – 30 Points QUESTION: What are the three types of surgical abortions and when are they performed? ANSWER: 1. Manual Vacuum aspiration (up to 10 weeks after start of last menses) 2. Vacuum Aspiration (6 -14 weeks after start of last menses). 3. Dilation and Evacuation (used after 14 weeks). • (Abortion is not used after 24 weeks except when there are serious health risks for the woman) Unwanted Pregnancy – 40 Points QUESTION: What factors have been found to be associated with increased risk of negative outcomes after voluntary abortion? ANSWER: • • • • • • • Previous psychiatric problems mid-trimester abortion low self-esteem poor prior knowledge of contraception ambivalence about decision pregnancy highly meaningful to woman not making own decision Unwanted Pregnancy – 50 Points QUESTION: What are closed adoptions as opposed to open adoptions? What did Lauderdale and Boyle’s study conclude about closed v. open adoptions? ANSWER: Definition: Open adoption is when the woman relinquishing helps select the family and may receive news of the child after birth. A closed adoption is done anonymously through an agency and the woman usually has little contact with the child post birth and does not know anything about the family she is relinquishing to. Lauderdale & Boyle study: • Both report avoiding developing attachment during pregnancy. • Most relinquish their child due to pressure from others or financial problems. • Women relinquishing in closed adoptions are more likely to have been pressured by others, have less contact with the infant after birth, have poorer pre-natal care and initiate the search for the child years later. • Women relinquishing in open adoptions are more likely to admit pregnancy to others and desire child to contact them but don’t initiate search. Pregnancy & Childbirth – 10 Points QUESTION: What hormone is measured in pregnancy tests and why are pregnancy tests uncertain in early pregnancy? ANSWER: HCG is measured and is similar to LH so the test is uncertain until HCG levels are higher than LH levels would ever be in a cycling woman. Pregnancy & Childbirth – 20 Points QUESTION: What major hormones does the placenta produce? What is unique about the way it produces one of these? ANSWER: • Estrogen (estrial)* • Progesterone • Human Placental Lactogen (and a number of other hormones similar to those produced by the anterior pituitary) *It can not make estrial from cholesterol so it makes it from androstenedione provided by the fetal adrenal gland. Pregnancy & Childbirth – 30 Points QUESTION: What comes from the ectoderm? Mesoderm? Endoderm? ANSWER: Ectoderm Central nervous system, peripheral nervous system, and epidermis Mesoderm Skeletal system, musculature, vasculature Endoderm Gut, lungs, liver Pregnancy & Childbirth – 40 Points QUESTION: What are three common signs that labor has begun? ANSWER: • release of a small amount of blood with mucus from the vagina (cervical plug) • uterine contractions at intervals less than 10 minutes • rupture of amniotic sac (water breaking) Pregnancy & Childbirth – 50 Points QUESTION: What are the three phases of the first stage of labor? What happens at each? ANSWER: Latent phase (contractions 5-20 min. apart, cervix 3-5 cm.) Active phase (contractions 3-4 min. apart, cervix 4-7 cm.) Transition (contractions every few minutes, cervix 8-10 cm.) Menopause – 10 Points QUESTION: How can a woman tell whether she has gone through menopause? ANSWER: Menopause has occurred if the woman has had no menses for 12 consecutive months. Menopause – 20 Points QUESTION: How is body fat level related to a woman’s estrogen level after menopause? ANSWER: High body fat is associated with higher post-menopause estrogen levels since androstenedione from the adrenal cortex is converted to estrogen (estrone) in fat. Menopause – 30 Points QUESTION: What are the benefits and risks of Estrogen Replacement Therapy (ERT)? ANSWER: Benefits: Can reduce estrogen-related symptoms of menopause such as hot flashes, genital changes, loss of sex drive, loss of calcium from bones, and risk of cardiovascular disease Risks: increases risk of endometrial cancer (so is rarely used for women with an intact uterus) Menopause – 40 Points QUESTION: What are some factors that a woman can control to reduce her risk of osteoporosis? What are some factors a woman cannot control? ANSWER: Steps to Take: • Have an active lifestyle (including weight-bearing exercise). • Avoid taking thyroid hormones. • Don’t smoke. • ERT/HRT stops calcium loss (but has risks!). • Non-estrogen treatments, such as Fosomax and Boniva, increase bone density. • Consume adequate calcium. Uncontrollable Factors: • Being Caucasian or Asian. • Being tall and thin (small-boned). • Having early menopause (in your 20’s or 30’s) or surgical menopause (removal of ovaries) Menopause – 50 Points QUESTION: What happens to women’s levels of estrogen, progesterone, GnRH, FSH and LH levels during menopause? What happens to sex steroid production by the adrenal cortex? ANSWER: • Estrogen and progesterone production from the ovaries is dramatically reduced. • GnRH, FSH, and LH levels become very high. • Hormone production by the adrenal cortex is unchanged. Androstenedione from the adrenal cortex is converted to estrone in fat. Review – 10 Points QUESTION: What are the four things released at ovulation? ANSWER: • • • • Follicular fluid corona radiate sticky cumulus the ovum Review – 20 Points QUESTION: 1. In recall studies, what symptoms do women report to be associated with the menstrual cycle? 2. In concurrent studies, what relationships between mood and behavior and the monthly cycle do women report? ANSWER: 1. a) An increase in negative moods and behaviors premenstrually. b) And sometimes an increase in positive moods during the follicular phase or midcycle. 1. a) More positive moods and behaviors during the follicular phase or at mid-cycle. b) They report no correlation between negative moods and behaviors and the premenstrual phase of the cycle. Review – 30 Points QUESTION: Male internal genitalia include what? What is required for male internal genitalia to develop? Male external genitalia? ANSWER: •Male internal genitalia include: seminal vesicles, epididymus, and the ejaculatory ducts and tubes. •Development of male internal genitalia requires: androgens, Mullerian Inhibiting Factor, and inductor substance. •Development of male external genitalia requires: Presence of androgens and the ability to respond to androgens Review – 40 Points QUESTION: Describe the estrogen and progesterone levels across the monthly cycle: ANSWER: Estrogen a) Levels increase on Day 1 and gradually increase throughout the preovulatory phase (because the follicles are growing) b) Surge 24 hours prior to ovulation. c) Levels decrease after surge (through ovulation). d)Levels rise during the postovulatory phase as the corpus luteum develops. Drop off just before menses when the corpus luteum dies. Progesterone a) Levels low on Day 1 b)Stay very low throughout the preovulatory phase c) Increase during the postovulatory phase with the development of the corpus luteum d) Drop off just before menses with the death of the corpus luteum Review – 50 Points QUESTION: What do CRH, TRH, Somatostatin, GHRH, GnRH, Dopamine and PSH do? What does inhibin (not a releasing hormone) do? ANSWER: •CRH - stimulates the production and release of ACTH •TRH - stimulates the production and release of TSH •Somatostatin - inhibits the production and release of GH •GHRH - stimulates the production and release of GH •GnRH - stimulates the production and release of both FSH and LH •Dopamine - inhibits the production and release of prolactin •PSH - stimulates the production and release of prolactin •Inhibin - acts at the anterior pituitary to inhibit the production and release of FSH