Helke is at BOOTH 213 This PowerPoint presentation will be available on www.helkeferrie.com /RESOURCES The website version will have a detailed, annotated bibliography from PubMed-based publications including first quarter of 2013 CONTACT helkeferrie@gmail.com 519-927-1049 Cancer Screening How Useful? Total Health April 7, 2013 Helke Ferrie Vitality Magazine and Kos Publishing Cancer Statistics 2012 LEADING cause of death in Canada 40% of all deaths: LUNG and COLORECTAL DEATH RATES DECLINING (grab the salt …) LIVER & THYROID significantly continuing to INCREASE No change in survival since 1950s Five-year relative survival ratio (RSR) for most common cancers, by sex, Canada, 2004-2006 RSR (%) 0 10 20 30 40 50 60 70 80 90 Tier 1 (>80%) Thyroid Testis Prostate Melanoma Breast Hodgkin lymphoma Body of Uterus Bladder Tier 2 Cervix Kidney Larynx Oral Colorectal Non-Hodgki lymphoma Leukemia Ovary Multiple myeloma Tier 3 (<50%) Stomach Brain Liver Males Lung Females Esophagus Pancreas Data source: Canadian Cancer Statistics 2011 100 ILLUSIONS Cancer is inherited/familial/genetic Mammography/PSA are preventive Cancer a local problem – remove it Cut-Burn-Poison improves survival FACT Early detection is NOT prevention Early detection is either diagnosis … or false alarm not unacknowledged often leads to unnecessary surgery, chemotherapy, and radiation May CAUSE cancer SICKNESS INDUSTRY CORRECT Q: What does health depend on? CORRECT A: Optimally functioning liver Cytochrome P450 - glutathione, P 53 spell check = tumor suppressor gene BAD SCIENCE & BAD ECONOMICS: What chemical will stop symptoms? Can this intervention be patented? Can government be made to pay ? BUT ….. !!!! My sister’s life was saved by a mammogram … my life was saved by a PSA test & surgery! My doctor surely must know … Health Canada couldn’t allow harmful procedures and drugs to be sold! “Faith is the enemy of reason.” P. Gotzsche Cochrane Collaboration P53 TUMOR SUPRESSOR GENE Produces a protein that forces cancer cells to commit suicide = apoptosis Robert A. Weinberg of MIT The Biology of Cancer p53 pathway: In a normal cell p53 is inactivated by its negative regulator, mdm2. Upon DNA damage or other stresses, p53 will allow either cell repair and survival or apoptosis. How p53 makes this choice is currently unknown. CA: most p53 dependent Esophagus, ovary, colorectal, head& neck, pancreas, lung, skin, stomach, bladder, brain, liver, breast CA: less p53 dependent Uterus, lymphoma, endocrine, bones, soft tissues, prostate, cervical CYTOCHROME P450 Toxins (drugs, carcinogens, radiation) stress out the liver’s super-detoxer, glutathione Glutathione is a tripeptide that protects every cell in our bodies from damage by free radicals and orchestrates the elimination of anything - loose glutathione and you die All immune function depends on P450 PSA Prostate specific antigen enzyme FDA approved 1994 - now $ 3 billion/y 80%+ not invasive – die with it not from it Rapid-growing prostate CA – no treatment PSA only useful after confirmed CA surgery At least 2/3 “diagnosis” false positive* HIGH RISK of impotence & diapers Dr. ABLIN New York Times March 10, 2010: “I never dreamed that my discovery [in 1970] would lead to such a profit-driven public health disaster. The medical community must confront reality and stop the inappropriate use of PSA screening [to] save billions and rescue millions of men from unnecessary, debilitating treatments” MAMMOGRAPHY Gotzsche, Mammography: Truth, Lies and Controversy, 2012 Cochrane Collab. S.S. Epstein, R. Bertell, B. Deaman, Dangers and Unreliability of mammography, Intern. J. Health Serv. 31 (3) 2001 CMAJ editorial Nov. 22, 2011 “Time to stop mammography screening?” CMAJ 2011 quote: “The main effect of screening is to produce patients with breast cancer from among healthy women who would have remained free of breast disease for the rest of their lives, had they not undergone screening… the best method we have to reduce the risk of breast cancer is to stop the screening program… if screening had been a drug, it would have been withdrawn from the market. Thus, which country will be first to stop mammography screening?” “…. 99.75% of the women screened unlikely to benefit” from Epstein, Bertell, Seaman study 2001 COLORECTAL CANCER Warning signs: constipation, blood in stool, weight & appetite loss, nausea, vomiting, fever Causes: 95% no genetic link – high fat diet, red meat, alcohol, obesity, smoking, lack of exercise P53 incapacitated, oncogenes over-expressed Surgery imperative when bowel obstructed Screening has not improved survival COLORECTAL CA TESTS Invasive, high radiation, high false positives even in discovered polyps Bowel prep and “conscious sedation” can be very traumatic and cause memory loss No better than PSA and mammography Screening will not prolong life Mortality unchanged since the 1950s INFLAMMATION 1 Virchov 1863 noted puss in all CA Inflammation 500 mill y.o. defense: all living things have inflammation enzymes, from fruit fly to us 1986 Harold F. Dvorak/Harvard: Cancer = “wounds that do not heal.” INFLAMMATION 2 R. A. Weinberg revised The Biology of Cancer 2006* Gene damage “the match that lights the fire, and inflammation is the fuel that feeds it” (S.A.2008) On/Off inflammation switch NF-KB (nuclear factor-kappa B) are disabled & “immune police” p53 * P53 can no longer” digest” tumors Inflammation turns H. pylori, Hep C etc to CA INFLAMMATION 3 Inflammation = code for proliferation = metastasis Inflammation = enemy of surgery Biopsies risk CA cell spread Tissue pressure in mammograms HELPFUL TESTS C-reactive protein - shows INFLAMMATION Thermography - pinpoints INFLAMMATION Hair analysis - reveals many CARCINOGENS ALL cancers require exposure to carcinogens Screening should serve inflammation C-REACTIVE PROTEIN Released in response to injury, inflammation, infection = leading blood marker of inflammation Diagnostic for both CA and HEART/STROKE Helpful to prevent these by making lifestyle changes, start detox, change diet THERMOGRAPHY Body temperature: Hippocrates 5th cent. BCE For breast cancer since 1956 FDA approved 1982 –as adjunctive tool Thermograms = physiology – noninvasive 90+% accuracy and CA seen up to 10 years earlier J. Obstetrics & Gynecology 1983 : 61% increased survival HAIR ANALYSIS Developed by WHO – used in forensics too Provides a profile of last 3 months of 37 toxins and mineral deficiencies in the body Correction of mineral needs and detox permits prevention of CA, stroke, heart attack, chronic diseases Various laboratories – naturopaths/physicians can order CAUSES OF CA FOOD & DRUGS Pesticides, herbicides, fungicides, food coloring, MSG, preservatives, stabilizers, “natural” flavors, fluoride, amalgams GM foods, antibiotics, hormones HRT, anti-depressants, cancer drugs, cholesterol drugs etc Sources: CPS, www.responsibletechnology.org ENVIRONMENT www.preventcancer.com The President’s Cancer Panel Report May 2010 Endocrine Disrupting Chemicals – 2012 by WHO UNEP IOMC, March 2013 American Academy of Environmental Medicine & IAOMT CANCER CAUSES ARE KNOWN CA research based on animal models ALL cancers can be induced artificially with absolute specificity by carcinogens and/or genetic modification ALL conventional cancer treatments derive from causing and treating artificially induced cancers in animals CA treatments are themselves carcinogenic Dr. G. Welch, Overdiagnosed, 2011 Peter Goetzsche, Mammography Screening, Cochrane 2012 Alan Cassels, Seeking Sickness, 2012 PLoS online-free Total Wellness by Dr. Sherry Rogers Helke Ferrie, Creative Outrage, Kos 2013 CONTINUED: D. L. Davis, The Secret History of the War on Cancer, 2007 S. S. Epstein, National Cancer Institute and American Cancer Society: Criminal Indifference … 2011 & The Breast Cancer Prevention Program N. Gonzalez, What Went Wrong, 2012 G. Faguet, The War On Cancer – Anatomy of Failure, 2004 CA – MAINSTREAM SUCCESS Uterine & cervical & skin only surgery Some breast CA – surgery only Kidney (localized adenocarcinoma) Some leukemias then detox & diet Some thyroid cancers Localized colon CA then detox & diet* Burton Goldberg & Ralph Moss CANCER TREATMENTS THAT REALLY WORK Gerson Institute California Dr. Nicholas Gonzalez New York Dr. Stanislav Burzynski Texas BEWARE! “New”, “breakthrough”, “experimental”, “expensive”* INVITATION TO A TRIAL Q: Who pays for this? Does your doctor get a recruiting fee? Drug compared to what? ROUTINE TEST – Q: By what guideline? Guideline members? Research on internet: “The there!”. truth is out SUMMARY Screening serves industry, not patients Prevention = life style & clean world House of Medicine has “many mansions”. No external authority – do your own research