RNA Transcription, Translation and Protein Synthesis RNA Phosphate Group O O=P-O O Nitrogenous base (A, U , G, C ) 5 CH2 O N Sugar (ribose) C4 C3 C1 C2 RNA • Function: obtain information from DNA & synthesizes proteins 3 differences from DNA 1. Single strand instead of double strand 2. Ribose instead of deoxyribose 3. Uracil instead of thymine 3 types of RNA 1. Messenger RNA (mRNA)- copies information from DNA for protein synthesis Codon- 3 base pairs that code for a single amino acid. codon 3 types of RNA 2. Transfer RNA (tRNA)collects amino acids for protein synthesis Anticodon-a sequence of 3 bases that are complementary base pairs to a codon in the mRNA 3 types of RNA 3. Ribosomal RNA (rRNA)- combines with proteins to form ribosomes Amino Acids • Amino acids- the building blocks of protein • At least one kind of tRNA is present for each of the 20 amino acids used in protein synthesis. Transcription - mRNA is made from DNA & goes to the ribosome Translation - Proteins are made from the message on the mRNA Transcription • In order for cells to make proteins, the DNA code must be transcribed (copied) to mRNA. • The mRNA carries the code from the nucleus to the ribosomes. Translation • At the ribosome, amino acids (AA) are linked together to form specific proteins. • The amino acid sequence is directed by the mRNA molecule. Amino acids ribosome Make A Protein • DNA sequence ATG AAA AAC AAG GTA TAG • mRNA sequence UAC UUU UUG UUC CAU AUC Make mRNA • mRNA sequence UAC UUU UUG UUC CAU AUC • tRNA sequence AUG AAA AAC AAG GUA UAG Make mRNA • tRNA sequence AUG AAA AAC AAG GUA UAG • Amino Acid sequence met lys asn lys val stop