WEB APPENDIX
Background information on ten areas of health policy
Below we present a summary of the evidence on the effectiveness of interventions and policies in each of the ten areas of health policy contributed by the authors of individual
chapters in our forthcoming edited book (1).
Tobacco
There is a wide range of interventions and policies which help reduce smoking in the
Pharmacotherapy, e.g. nicotine replacement therapies, increases the odds of successful
Increasing tobacco prices through increased taxation reduces overall consumption and
prevalence of tobacco use (7).
Alcohol
There is extensive evidence on the effectiveness of a range of alcohol control policies (8).
The three best buys for alcohol policy are price increase, limits on availability, and bans on
advertising (9). When alcohol becomes cheaper, more is consumed and more harm ensues
(10). When alcohol is more difficult to get, less is consumed and less harm results (11).
Commercial communications, particularly through social media and electronic communication outlets, encourage non-drinkers to start drinking and existing drinkers to
Food and nutrition
Although the effectiveness of food and nutrition policies is less well established than that of tobacco and alcohol control policies, there is evidence for effectiveness in a number of
areas. Adding iodine to salt helps prevent iodine deficiency (13, 14). Intensive support and
encouragement to reduce salt intake has led to a reduction in salt eaten, and also lower
and fat intake and an increase in the intake of fruit, vegetables, and fibre lead to modest improvements in cardiovascular risk factors, such as blood pressure and cholesterol levels
the Netherlands has been estimated to have reduced the annual number of deaths from
ischemic heart disease in the Netherlands by 10% (19).
Fertility, pregnancy and childbirth
Access to contraceptive services also reduces unwanted pregnancies and adolescent pregnancies; having an unplanned or unintended pregnancy places women at greater risk for
poor outcomes, such as preterm delivery or having a low birth-weight infant (20). Smoking
cessation programs offered during antenatal care reduce smoking and have an impact on
low birth-weight and preterm birth (21). Screening for congenital anomalies is associated
with lower perinatal mortality, and with a lower live birth prevalence of certain lethal or
incurable congenital anomalies (22). Safe delivery services reduce maternal mortality, and
delivery of pre-term infants in maternity units with on-site neonatal intensive care is
associated with lower mortality and higher survival without disability (23).
Child health
Vaccination of children against diphtheria, measles and other childhood infections is highly
Infectious diseases
Vaccination against influenza prevents pneumonia, hospital admissions and deaths among
elderly people (30), although the evidence is no longer considered entirely convincing (31).
Effective means of preventing the transmission of HIV include voluntary counselling and
intravenous drug users (35). Improved hand hygiene, contact precautions and admission
screening can reduce infections with Methicillin Resistant Staphylococcus aureus (MRSA)
(36), as can “search and destroy” programmes (37).
Hypertension detection and treatment
Adequate control of hypertension by drugs reduces risks of cardiovascular disease
considerably (38, 39), also among elderly patients (40). Within primary care, organized
systems for regular follow-up, implementation of drug therapy by means of a vigorous stepped care approach, and self-monitoring and appointment reminders are useful adjuncts
to improve blood pressure control (41).
Cancer screening
Most experts agree that screening for cervical and breast cancer is effective (42, 43). The
available evidence suggests that well-organised screening programmes for cervical
cancer substantially reduce incidence and mortality from this disease (44). Effectiveness of
screening for breast cancer has been assessed by means of randomised controlled trials with
Road safety
There are many interventions that have been shown to reduce road traffic injuries. The most important ones are controlling speed, stopping driving when under the influence of alcohol, enforcing use of safety equipment such as motorcycle and cycle helmets and seat belts, increasing conspicuousness of road users, improving vehicle crash protection, and making infrastructural changes to road design to ensure that speed is controlled and that vulnerable road users are not exposed to unnecessary risk by mixing them with motorized
Air pollution
Adverse effects of air pollution on human health have been well documented (49). National
and international policies to reduce emissions, e.g. by setting ceilings for emissions during combustion of fuels in power plants and industry and on the sulphur content of fuels, have
been effective in reducing sulphur dioxide emissions (50). Similar policies have contributed
to the decline of emissions of particulate matter and nitrogen oxide, and to a reduction of
the number of days in which ozone concentrations exceeded a maximum value (51).
Table A1. Health policy performance indicators, by country a. Tobacco, alcohol and food policies b. Fertility/pregnancy/childbirth, child health, and infectious disease control policies c. Hypertension, cancer screening, road traffic safety, and air pollution policies d. Summary score
Notes for table 2a:
- TCS=Tobacco Control Scale (source:(52)).
- Msmok=Male smoking prevalence (%) (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- MLungca=Male lung cancer mortality rate(source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- BtG=Bridging the Gap Alcohol Policy Score (source: (53)).
- AlcCons=Alcohol consumption including unrecorded consumption (source:(54)).
- MLivcir=Male liver cirrhosis mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- IodDef=Iodine deficiency (source: (55).
- Fat intake=Total energy available from fat (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- Fruit&veg intake=Fruits and vegetable available per year (source: WHO HFA Database
( http://data.euro.who.int/hfadb/ ) ).
Notes for table 2b:
- TeenPregn=Percentage of teenage pregnancies (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- NeonatMo=Neonatal mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- MaternMo=Maternal mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- MeasImmun=Measles immunization rate (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- SafetyScore=Child Safety Alliance safety grade (source: (56).
- PostneoMo=Post neonatal mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- AidsInc=Incidence of Aids (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- MRSA infections = infections with Methicillin Resistant Staphylococcus Aureus (source: (57))
- Inflvacc=Influenza vaccination coverage among 65 and older (source:(58)).
Notes for table 2c:
- MSBP=Male average systolic blood pressure (source: (59).
- FStrokeMo=Female stroke mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- BreastScr=breast cancer screening implementation Source: (43).
- CervcaMo=Cervical cancer mortality (source: WHO HFA Database ( http://data.euro.who.int/hfadb/ ) ).
- Seatbelt=Seatbelt wearing among front seat car occupants (source: (60)).
- SO2=Sulphur dioxide emissions (source: Eurostat ( http://epp.eurostat.ec.europa.eu/ ) ).
- UrbanOzone=Urban population exposure to air pollution by ozone (source: Eurostat
( http://epp.eurostat.ec.europa.eu/ ) ).
Notes for Ошибка! Источник ссылки не найден.d: Summary scores were calculated from data in Tables 2a-2c. First, the total number of observations was determined. Then, for each country the percentage of scores falling in the upper tertile and the percentage of scores falling in the lower tertile of all available scores were calculated. Finally, for each country a summary score was calculated as the difference between the percentage of scores falling in the upper and the percentage of scores falling in the lower tertile.
Indicator
Unit
Year
Nordic
Finland
Sweden
Norway
Iceland
Denmark
Britain & Ireland
United Kingdom
Ireland
Continental
Netherlands
Belgium
Luxembourg
Germany
Switzerland
Austria
Mediterranean
France
Spain
Portugal
Italy
Malta
Greece
Cyprus
Western Balkans
Slovenia
Croatia
Bosnia-Hercegovina
Serbia
Montenegro
TFYR Macedonia
Albania
Centre & East
Poland
Czech Republic
Slovakia
Hungary
Romania
Bulgaria
(f) Soviet Union
Estonia
Latvia
Lithuania
Belarus
Ukraine
Republic of Moldova
Russian Federation
Georgia
Armenia
Azerbaijan
Tobacco
TCS
0-100
2010
Alcohol
MSmok MLungca BtG
% d/100000 0-40
2008 2007 2005
Food
AlcCons MLivcir IodDef Fat intake Fruit&veg intake l/cap d/100000 %<100ug/l%Energy kg/cap
2009 2008 <2007 2007 2007
52
51
62
61
46
77
69
46
50
33
37
48
32
55
46
43
47
52
32
40
44
43
34
41
34
45
40
43
44
41
26
13
21
21
28
22
31
32
25
28
23
27
32
31
29
26
39
22
31
37
30
32
39
45
39
53
50
51
55
38
45
28
45
48
63
52
53
68
79
64
54
44
47
62
65
43
60
44
69
31
73
85
83
79
91
71
69
106
67
62
86
76
79
69
60
50
74
32
85
17
32
36
35
17
25
26
16
12
6
6
14
6
14
10
7
4
5
8
9
10
16
5
9
14
8
7
16
14
13
12
9
8
8
13
13
13
10
12
13
13
11
13
13
13
13
10
8
11
10
15
13
13
7
14
17
15
14
16
11
14
13
29
8
5
3
15
9
6
17
9
22
16
13
17
13
9
8
9
40
39
17
27
25
40
70
61
32
38
25
56
106
29
28
30
47
19
48
69
56
31
67
33
39
36
21
33
35
47
50
0
41
24
22
22
9
17
10
57
55
13
15
57
47
11
67
77
60
14
56
27
58
4
6
13
36
36
35
39
36
38
35
37
40
39
37
40
39
42
42
35
39
29
37
39
34
33
40
26
36
29
30
36
34
39
28
31
25
36
27
33
26
21
25
21
25
16
172
205
220
222
209
218
219
239
201
276
182
169
251
214
243
287
295
318
404
269
197
193
174
168
187
205
153
108
184
102
394
180
144
154
195
209
132
211
234
256
299
222
Indicator
Unit
Year
Nordic
Finland
Sweden
Norway
Iceland
Denmark
Britain & Ireland
United Kingdom
Ireland
Continental
Netherlands
Belgium
Luxembourg
Germany
Switzerland
Austria
Mediterranean
France
Spain
Portugal
Italy
Malta
Greece
Cyprus
Western Balkans
Slovenia
Croatia
Bosnia-Hercegovina
Serbia
Montenegro
TFYR Macedonia
Albania
Centre & East
Poland
Czech Republic
Slovakia
Hungary
Romania
Bulgaria
(f) Soviet Union
Estonia
Latvia
Lithuania
Belarus
Ukraine
Republic of Moldova
Russian Federation
Georgia
Armenia
Azerbaijan
%
2008
1.3
3.7
10.5
6.5
5.7
6.5
5.0
2.0
2.9
4.4
1.4
6.8
2.8
1.8
9.9
13.8
14.0
9.1
14.3
5.4
7.0
5.6
6.4
8.7
4.9
3.1
6.6
6.1
11.8
12.7
1.4
2.8
1.8
2.3
0.9
3.3
2.2
1.6
2.4
3.4
1.5
6.2
3.0
d/1000 d/100000 %
2009 2007-9 2008
2.0
1.6
2.1
1.0
2.7
3.2
2.3
2.9
2.6
1.4
2.6
3.1
2.5
2.4
2.1
3.4
2.5
5.7
2.0
1.9
1.6
4.3
10.5
4.9
4.1
8.6
2.5
4.0
1.6
3.1
3.4
5.5
5.0
3.2
5.0
2.8
3.1
5.6
7.8
6.4
11.8
8.1
6.0
3.9
4.2
4.5
0.0
7.8
7.6
3.2
4.7
5.2
5.0
3.0
7.2
3.4
5.3
2.2
7.9
10.0
11.6
19.2
13.9
17.1
3.1
3.7
5.0
14.7
21.7
7.9
28.2
4.9
5.6
20.2
26.4
21.7
28.6
29.2
28.5
99
99
100
95
97
99
99
95
95
95
99
96
98
92
89
95
95
97
96
97
91
72
99
97
97
96
83
98
97
97
99
98
94
98
89
92
93
0-60
2009
40
29
28
30
35
34
33
39
41
42
37
27
32
41
39
43
49
40
31
46
30
Infectious diseases
PostneoMort MRSA Inflvacc d/1000 c/100000 %insensitive
2009 2009 2010 2008
0.6
0.9
1.0
0.8
0.7
1.5
1.0
1.0
1.4
0.7
1.3
0.9
1.3
1.1
1.2
1.6
1.0
2.4
1.1
1.4
0.8
1.0
4.1
2.1
1.7
3.2
5.3
1.6
1.2
2.6
1.7
4.3
3.6
1.8
2.7
2.1
3.8
4.1
4.3
4.7
3.1
3.7
3.8
0.5
0.7
0.4
0.6
0.7
1.2
0.6
1.5
1.1
1.4
0.6
1.9
0.8
1.6
3.0
5.1
1.6
2.2
0.9
1.5
0.5
0.3
0.5
0.5
0.4
0.8
0.4
0.3
0.0
0.2
1.0
0.4
4.6
4.6
1.6
4.0
2.4
2.6
5.3
2.6
0.7
0.4
0.3
0.0
0.0
0.0
5.7
2.5
2.6
2.1
18.2
0.2
1.7
0.2
1.1
17.3
13.2
0.0
3.2
5.9
2.2
3.0
1.2
1.1
4.7
13.5
5.3
12.5
47
55
53
73
61
82
63
51
65
9
29
33
67
67
50
66
28
Indicator
Unit
Year
Nordic
Finland
Sweden
Norway
Iceland
Denmark
Britain & Ireland
United Kingdom
Ireland
Continental
Netherlands
Belgium
Luxembourg
Germany
Switzerland
Austria
Mediterranean
France
Spain
Portugal
Italy
Malta
Greece
Cyprus
Western Balkans
Slovenia
Croatia
Bosnia-Hercegovina
Serbia
Montenegro
TFYR Macedonia
Albania
Centre & East
Poland
Czech Republic
Slovakia
Hungary
Romania
Bulgaria
(f) Soviet Union
Estonia
Latvia
Lithuania
Belarus
Ukraine
Republic of Moldova
Russian Federation
Georgia
Armenia
Azerbaijan
Hypertension
MSBP
Cancer screening
FStrokeMort
Road traffic safety Air pollution
PedMort SO2 Urban Ozone mmHg d/100000 0-2
2008 2008 <2000 d/100000 %
2008 2007 2007 2007 2009 2009
135
132
135
130
130
131
135
131
129
131
133
131
131
131
130
135
131
132
129
131
136
136
137
135
134
134
135
134
136
136
133
133
139
137
137
137
137
134
132
40
39
37
35
45
39
34
40
27
32
24
34
70
43
51
83
41
53
105
140
78
64
71
82
76
154
163
63
123
110
141
184
210
2
2
2
2
1
2
1
2
1
2
1
1
1
2
2
1
1
0
1
2
1
0
0
0
0
0
1
2
0
1
0
0
2
1
1
0
0
0
0
0
0
0
1.5
2.3
3.0
0.0
3.1
2.6
4.7
2.4
3.5
2.9
1.2
2.9
2.3
2.6
4.8
2.0
2.4
2.2
1.7
3.5
5.5
5.0
12.5
8.5
13.4
4.2
7.8
5.2
6.5
7.8
16.2
9.1
7.9
9.9
11.5
6.6
8.3
10.4
8.1
6.3
12.3
7.0
89
96
93
88
91
86
94
79
95
86
89
98
89
90
65
96
75
81
85
55
30
74
90
71
80
90
77
33
0.9
0.7
0.8
1.2
0.6
1.2
0.5
1.2
0.6
0.5
1.0
0.9
1.2
1.1
0.8
0.2
1.6
1.1
1.9
2.1
4.6
3.7
5.2
2.6
8.5
2.1
1.8
2.8
2.2
5.5
3.3
2.5
2.5
2.6
3.1
9.9
8.0
8.7
10.8
0.2
0.1
0.1
0.1
0.2
0.4
0.1
0.2
0.1
0.2
0.3
0.2
0.3
0.3
0.2
0.2
0.5
0.4
0.3
0.8
1.8
1.6
1.4
2.1
7.5
1.4
0.6
1.9
0.9
0.8
1.3
0.7
1.9
1.5
2.6
5.9
4.6
4.3
5.7
6.9
11.1
3.2
3.3
2.7
6.5
7.4
2.3
7.1
6.3
5.5
1.7
2.5
4.9
9.4
7.2
3.8
18.0
38.0
21.5
5.7
22.6
16.6
11.8
8.0
21.4
86.5
40.9
1.8
10.8
1689
2013
879
2446
1123
1197
1360
2787
3130
4701
5097
3859
5207
3268
6196
8084
4959
3112
4288
8051
6809
4420
3265
1675
1260
2304
Nordic
Finland
Sweden
Norway
Iceland
Denmark
Britain & Ireland
United Kingdom
Ireland
Continental
Netherlands
Belgium
Luxembourg
Germany
Switzerland
Austria
Mediterranean
France
Spain
Portugal
Italy
Malta
Greece
Cyprus
Western Balkans
Slovenia
Croatia
Bosnia-Hercegovina
Serbia
Montenegro
TFYR Macedonia
Albania
Centre & East
Poland
Czech Republic
Slovakia
Hungary
Romania
Bulgaria
(f) Soviet Union
Estonia
Latvia
Lithuania
Belarus
Ukraine
Republic of Moldova
Russian Federation
Georgia
Armenia
Azerbaijan
Summary score
24
25
23
25
24
24
26
18
10
18
17
14
15
15
18
16
14
25
25
25
16
15
15
26
24
25
24
25
26
27
23
24
27
27
23
20
27
27
25
23
21
27
26
17
32
17
12
8
8
35
11
10
11
18
21
33
7
17
13
14
12
4
12
13
13
20
54
54
40
54
56
50
33
52
58
67
59
35
45
67
89
84
83
48
48
46
-4
12
-17
-28
-42
-33
15
-17
-60
-17
-18
0
-13
-73
-56
-69
-50
-67
-32
-32
-28
-25
-33
31
42
16
33
52
35
19
35
46
48
56
17
25
63
89
84
78
43
37
38
21
20
35
40
50
42
19
28
70
28
35
21
47
80
72
81
64
44
36
40
38
80
53
23
13
24
21
4
15
15
17
13
19
4
17
20
11
8
0
4
4
0
5
1. Mackenbach JP, McKee M, editors. Successes and failures of health policy in Europe over four decades: Diverging trends, converging challenges. Buckingham: Open University
Press; (in press).
2. World Health Organization. MPOWER: A policy package to reverse the tobacco epidemic. Geneva: World Health Organization, 2008.
3. IARC. IARC Handbooks of Cancer Prevention, Tobacco Control, Volume 13: Evaluating the effectiveness of smoke-free policies. Lyon, France: International Agency for Research on
Cancer; 2009.
4. Stead LF, Perera R, Mant D. Nicotine replacement therapy for smoking cessation. .
Cochrane Database of Systematic Reviews. 2008;1(CD000146).
5. Bala M, Strzeszynski L, Cahill K. Mass media interventions for smoking cessation in adults. Cochrane Database Syst Rev. 2008(1):CD004704. Epub 2008/02/07.
6. Blecher E. The impact of tobacco advertising bans on consumption in developing countries. J Health Econ. 2008;27(4):930-42.
7. Chaloupka F, Leon, M., Straif, K. (collaborators: N. Nargis, L. Joossens, L. Nguyen, L.
Clancy, L. Currie, S. Gallus, C. La Vecchia, F. Godfrey, C. Van Walbeek, E. Fernandez, S.
Delipalla, AM Perucic, Z. Onder, A. Gilmore, E. Blecher, TW Hu, D. Levy, H. Ross, J. Tauras,
Frank van Driessche, R. Iglesias, M. Pekurinen, A. Yurekli, K. Smith.). Effectiveness of tax and price policies in tobacco control. Tobacco control. 2011;20:235-8.
8. World Health Organization . Evidence for the effectiveness and cost-effectiveness of interventions to reduce alcohol-related harm. Copenhagen: WHO Regional Office for Europe;
2009.
9. World Health Organization and World Economic Forum . From Burden to “Best Buys”:
Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income
Countries . Copenhagen: WHO/WEF; 2011.
10. Österberg E . Pricing of alcohol . In: Anderson P , Møller L , Galea G , editors. Alcohol in the
European Union . Copenhagen : World Health Organization ; 2012.
11. Bryden A, Roberts B, McKee M, Petticrew M. A systematic review of the influence on alcohol use of community level availability and marketing of alcohol. Health Place.
2012;18(2):349-57. Epub 2011/12/14.
12. de Bruijn A . The impact of alcohol marketing . In: Anderson P , Møller L , Galea G , editors.
Alcohol in the European Union . Copenhagen : World Health Organization ; 2012.
13. World Health Organization. Iodine deficiency in Europe. A continuing public health problem. Geneva: World Health Organization; 2007.
14. World Health Organization. WHO European Action Plan for Food and Nutrition Policy
2007-2012 Copenhagen: WHO Regional Office for Europe, 2008.
15. Hooper L, Bartlett C, Davey SG, Ebrahim S. Advice to reduce dietary salt for prevention of cardiovascular disease. Cochrane Database Syst Rev. 2004(1):CD003656. Epub
2004/02/20.
16. Hooper L, Summerbell CD, Thompson R, Sills D, Roberts FG, Moore H, et al. Reduced or modified dietary fat for preventing cardiovascular disease. Cochrane Database Syst Rev.
2011(7):CD002137. Epub 2011/07/08.
17. Brunner EJ, Rees K, Ward K, Burke M, Thorogood M. Dietary advice for reducing cardiovascular risk. Cochrane Database Syst Rev. 2007(4):CD002128. Epub 2007/10/19.
18. Stender S, Dyerberg J, Bysted A, Leth T, Astrup A. A trans world journey. Atheroscler
Suppl. 2006;7(2):47-52. Epub 2006/05/23.
19. Katan MB. Regulation of trans fats: the gap, the Polder, and McDonald's French fries.
Atheroscler Suppl. 2006;7(2):63-6. Epub 2006/05/23.
20. Shah PS, Balkhair T, Ohlsson A, Beyene J, Scott F, Frick C. Intention to become pregnant and low birth weight and preterm birth: a systematic review. Maternal and child health journal. 2011;15(2):205-16. Epub 2009/12/17.
21. Lumley J, Chamberlain C, Dowswell T, Oliver S, Oakley L, Watson L. Interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev.
2009(3):CD001055. Epub 2009/07/10.
22. Khoshnood B, Greenlees R, Loane M, Dolk H. Paper 2: EUROCAT public health indicators for congenital anomalies in Europe. Birth defects research Part A, Clinical and molecular teratology. 2011;91 Suppl 1:S16-22. Epub 2011/03/08.
23. Ozminkowski RJ, Wortman PJ, Roloff DW. Inborn/outborn status and neonatal survival : a meta-analysis of non randomised studies. Stat Med. 1988;7:1207-21.
24. van Boven M, Kretzschmar M, Wallinga J, O'Neill PD, Wichmann O, Hahne S.
Estimation of measles vaccine efficacy and critical vaccination coverage in a highly vaccinated population. J R Soc Interface. 2010;7(52):1537-44. Epub 2010/04/16.
25. Gilbert R, Salanti G, Harden M, See S. Infant sleeping position and the sudden infant death syndrome: systematic review of observational studies and historical review of recommendations from 1940 to 2002. Popul Stud (Camb). 2005;34:874-87.
26. Gilbert R, Salanti G, Harden M, See S. Infant sleeping position and the sudden infant death syndrome: systematic review of observational studies and historical review of recommendations from 1940 to 2002. International journal of epidemiology. 2005;34:874-
87.
27. World Health Organization Europe. Policies to reduce unintentional injuries from falls, drowning, poisoning, fires and choking in children and adolescents. Copenhagen: WHO;
2007.
28. Thompson D, Rivara F. Pool fencing for preventing drowning of children. Cochrane database of systematic reviews. 1998;1:CD001047.
29. Branche C, Stewart S. Lifeguard effectiveness: a report of the working group. Atlanta:
Centres for Disease Control and Prevention, 2001.
30. Rivetti D, Jefferson T, Thomas R, Rudin M, Rivetti A, Di Pietrantonj C, et al. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev. 2006(3):CD004876.
Epub 2006/07/21.
31. Jefferson T, Di Pietrantonj C, Al-Ansary LA, Ferroni E, Thorning S, Thomas RE. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev. 2010(2):CD004876.
Epub 2010/02/19.
32. Voluntary HIV-1 Counseling and Testing Efficacy Study Group. Efficacy of voluntary
HIV-1 counselling and testing in individuals and couples in Kenya, Tanzania, and Trinidad: a randomised trial. The Voluntary HIV-1 Counseling and Testing Efficacy Study Group. Lancet.
2000;356(9224):103-12. Epub 2000/08/30.
33. Donnell D, Baeten JM, Kiarie J, Thomas KK, Stevens W, Cohen CR, et al. Heterosexual
HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis.
Lancet. 2010;375(9731):2092-8. Epub 2010/06/12.
34. Peersman GV, Levy JA. Focus and effectiveness of HIV-prevention efforts for young people. AIDS. 1998;12 Suppl A:S191-6. Epub 1998/06/20.
35. Wodak A, Cooney A. Effectiveness of sterile needle and syringe programming in reducing HIV/AIDS among injecting drug users. Geneva: WHO; 2004.
36. Edgeworth JD. Has decolonization played a central role in the decline in UK methicillin-resistant Staphylococcus aureus transmission? A focus on evidence from intensive care. J Antimicrob Chemother. 2011;66 Suppl 2:ii41-7. Epub 2010/09/21.
37. Bootsma MC, Diekmann O, Bonten MJ. Controlling methicillin-resistant
Staphylococcus aureus: quantifying the effects of interventions and rapid diagnostic testing.
Proc Natl Acad Sci U S A. 2006;103(14):5620-5. Epub 2006/03/28.
38. Turnbull F, Blood Pressure Lowering Treatment Trialists C. Effects of different bloodpressure-lowering regimens on major cardiovascular events: results of prospectivelydesigned overviews of randomised trials. Lancet. 2003;362(9395):1527-35. Epub
2003/11/15.
39. Wright JM, Musini VM. First-line drugs for hypertension. Cochrane Database Syst Rev.
2009(3):CD001841. Epub 2009/07/10.
40. Musini VM, Tejani AM, Bassett K, Wright JM. Pharmacotherapy for hypertension in the elderly. Cochrane Database Syst Rev. 2009(4):CD000028. Epub 2009/10/13.
41. Glynn LG, Murphy AW, Smith S, Schroeder K, Fahey T. Interventions used to improve control of blood pressure in patients with hypertension. Cochrane Database Syst Rev. 2010.
42. Von Karsa L, Anttila A, Ronco G, Ponti A, Malila N, Arbyn M, et al. Cancer screening in the European Union. Report on the implementation of the Council Recommendation on cancer screening, first report. International Agency for Research on Cancer & Directorate
General for Health and Consumers., 2008.
43. von Karsa L, Anttila A, Ronco G, et al. Cancer Screening in the European Union. Report on the implementation of the Council Recommendation on cancer screening. Luxembourg:
European Commission and International Agency for Research on Cancer, 2008.
44. International Agency for Research on Cancer. Cervix Cancer Screening. Lyon:
International Agency for Research on Cancer 2005. 416 p.
45. International Agency for Research on Cancer. Breast Cancer Screening. Lyon: lnternational Agency for Research on Cancer; 2002. 221 p.
46. Gotzsche PC, Jorgensen KJ, Zahl PH, Maehlen J. Why mammography screening has not lived up to expectations from the randomised trials. Cancer Causes Control.
2012;23(1):15-21. Epub 2011/11/11.
47. Racioppi F. Preventing road traffic injury: a public health perspective for Europe.
Copenhagen: WHO Regional Office for Europe 2004.
48. Peden M. World report on road traffic injury prevention. Geneva: World Health
Organization, 2004.
49. World Health Organization. Health aspects of air pollution. Results of the WHO project "Systematic review of health aspects of air pollution in Europe". Copenhagen: WHO
Regional Office for Europe; 2004.
50. Vestreng V, Myhre G, Fagerli H, Reis S, Tarrason L. Twenty-five years of continuous sulphur dioxide emission reduction in Europe. Atmos Chem Phys Discuss. 2007;7:5099–143.
51. European Environment Agency. Air quality in Europe - 2011 report. Luxembourg:
2011.
52. Joossens L, Raw M. The Tobacco Control Scale 2010 in Europe. Brussels: Association of European Cancer Leagues, 2011.
53. Karlsson K, Osterberg E. Scaling alcohol control policies across Europe. Eurocare
Bridging the Gap Project. 2007.
54. Anderson P, Møller L, Galea G. Alcohol in the European Union. Consumption, harm and policy approaches. Copenhagen: World Health Organization, 2012.
55. Andersson M, de Benoist B, Darnton-Hill I, Delange F. Iodine defi ciency in Europe: a continuing public health problem. Geneva: Wold Health Organization and UNICEF, 2007.
56. European Child Safety Alliance. Child Safety Report Card 2009. Europe Summary for
24 countries. Amsterdam: European Child Safety Alliance 2009.
57. ECDC. Susceptibility of Staphylococcus aureus isolates to Methicillin in participating countries in 2010. URL: http://ecdc.europa.eu/en/activities/surveillance/EARS-
Net/database/Pages/table_reports.aspx
. Stockholm2012.
58. O’Flanagan D, Cotter S, Mereckiene J. National Seasonal Influenza Vaccination Survey in Europe, 2007/2008 Influenza season. Vaccine European New Integrated Collaboration
Effort (VENICE), 2009.
59. Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, et al. National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5.4 million participants. Lancet. 2011;377(9765):568-77. Epub 2011/02/08.
60. World Health Organization. European status report on road safety. . Copenhagen:
WHO Regional Office for Europe, 2009.