WHO Strategy on Research for Health Rob Terry – Project Manager, RPC WHO Strategy on Research for Health WHO’s role in research for health….. and the role of research in WHO… Recognizes research as central to progress in global health Identifies how WHO can work with Member States and partners to harness knowledge, science and technology to produce research evidence and tools to improve health outcomes. 2| WHO Strategy on Research for Health | January 2009 Sustained Global interest 1990: Commission on Health Research for Development 1996: Ad Hoc Committee on Health Research Relating to Future Intervention Options 2000: International Conference on Health Research for Development (Bangkok) 2004: Ministerial Summit on Health Research (Mexico) 2008: Bamako Ministerial Forum on Research for Health 3| WHO Strategy on Research for Health | January 2009 Complex array of initiatives Member States looking to WHO for guidance and leadership 4| WHO Strategy on Research for Health | January 2009 Mandate Resolution WHA60.15 at 60th World Health Assembly May 2007 requesting the DG… "to submit to the Sixty-Second World Health Assembly (2009) a strategy on the management and organization of research activities within WHO" 5| WHO Strategy on Research for Health | January 2009 Strategy development - a participatory process Regional offices Special Programmes, HQ CCs Implementation Planning INPUTS 100 Stakeholder Interviews 6| Strategy+ annexes Emergent Emergent Themes Working drafts Themes Online & Face to face workshops Advisory Committe e on Health Research Evaluation Framework External & Internal Reference Groups Rolling Dialogue: Virtual & Face-to-Face WHO Strategy on Research for Health | January 2009 WHO Research Strategy – WHA 2009 Executive Board Jan 09 EB124/4.9 Guidance from the Director General 7| "….not spread our resources too thin…know our comparative advantage …stick with activities that WHO is uniquely well-suited to perform" "make evidence have the right impact… strengthen the legitimacy, quality and efficiency of our policy development processes" "...ensure that the best practices that science can devise are being followed" "….integrate WHO's research activities to more strategically address a common health research agenda" WHO Strategy on Research for Health | January 2009 What we heard from the consultation Bridge gap between policy makers and researchers. Champion cause that evidence is needed to address priority public health needs “Get out of the health box”- links with economic, social, cultural factors. How these factors shape health outcomes and how health impacts on them. Translate research questions and findings into terms (e.g. cost savings) that policy makers and practitioners find persuasive Focus on application or implementation of existing know-how Build, in pragmatic ways, local capacity (individuals and institutions) to develop and use relevant evidence 8| WHO Strategy on Research for Health | January 2009 What we heard from the consultation Conducted according to sound standards and ethical principles Well communicated and used locally Use a shared, broader definition of research: Application, Implementation and Evaluation. WHO to support and guide countries; decision making and accountability is countries' responsibility. Evidence-based policy vital in WHO’s work and core public health function 9| WHO Strategy on Research for Health | January 2009 WHO Strategy on Research for Health 10 | WHO Strategy on Research for Health | January 2009 Research for health – Three principles Quality - WHO commits itself to high-quality research that is ethical, expertly reviewed, efficient, effective, accessible to all, and carefully monitored and evaluated. Impact - WHO gives priority to research and innovation that has the greatest potential to improve global health security, accelerate health-related development, redress health inequities and help to attain the Millennium Development Goals. Inclusiveness - The Secretariat undertakes to work in partnership with Member States and stakeholders, to take a multisectoral approach to research for health, and to support and promote the participation of communities and civil society in the research process. 11 | WHO Strategy on Research for Health | January 2009 VISION decisions and actions to improve health and enhance health equity are grounded in evidence from research. MISSION WHO, Member States and partners work together to harness knowledge, science and technology to produce research evidence and tools to improve health CAPACITY Champion research that addresses priority health needs Support the development of robust national health research systems STANDARDS TRANSLATION Promote good research practice Strengthen links between research, policy and practice ORGANIZATION Strengthen the research culture across WHO WHO STRATEGY ON RESEARCH FOR HEALTH 5 Goals PRIORITIES Organization Working with Member States and partners, WHO will: Establish governance structures to lead, manage, coordinate and maintain accountability for research within WHO; Develop and implement a WHO Code of Good Research Practice; Strengthen existing mechanisms for good research practice; Code of good Enhance professional staff competencies; Research practice Improve access to WHO-affiliated research by What success will look like: WHO staff better understand, value and use evidence in planning, implementing and evaluating programmes and activities and in setting norms and standards; All research supported by WHO adheres to the Organization’s Code of Good Research Practice and is subject to scientific review and, where appropriate, ethical review; every guideline and recommendation is evidence-based and every article is peer reviewed; WHO’s role in research and the role of research within WHO are clearly communicated; organization; a leader in supporting or performing highquality research; a champion of the need for research and for being an effective partner in facilitating highquality research at global, regional and country level; developing a publicly accessible repository; Improve performance in research partnerships by: i) reviewing partnership admin processes; and ii) proactively seeking to engage with partners across all sectors that impact on research for health; Improve communications on the Organization’s involvement in research, monitoring and evaluation of this strategy. 13 | WHO Strategy on Research for Health | January 2009 WHO a more effective inasresearch WHO is partner widely regarded a credible, evidence-based WHO commits sufficient resources to support core functions necessary for the implementation of the strategy. Priorities Working with Member States and What success will look like: partners, WHO will: Ensure mechanisms are in place to synthesize data on gaps in research relating to current health and health system challenges at national and global levels; Convene high-level consultations to identify and build consensus around priorities; greater awareness of, and action on, research priorities at a national level; greater awareness of, and action on, research priorities at a regional and global level; Produce a report every four years on global research priorities with an assessment of the alignment of financial and human resources with research agendas; improved cooperation and coordination among research funders and other key partners to align global resources to meet priority health research needs; for such research agendas; Convene high-level Develop comprehensive research agendas for specific Consultation of funders plans priority areas and develop resource-mobilization Advocate support for research areas; Strengthen the coherence of WHO research activities by establishing mechanisms for periodically reviewing the portfolio of research agendas, including decision criteria for initiation, course corrections and exit strategies of programmes. 14 | WHO Strategy on Research for Health | January 2009 Better alignment of funders around priority areas more robust agendas for research on specific priority areas that are facilitated by WHO. Greater coherence and clarity on how WHO is supporting/actively engaged in these specific agendas. Capacity Working with Member States and partners, WHO will: What success will look like: Strengthen advocacy for the value of research and for the development of robust national health research systems; Greater investment in research for health by countries and from other sectors; All countries, especially low- and middle-income ones, have national research strategies; Develop tools and guidelines for strengthening national capacity; External stakeholders align their research investments with national research strategies; Promote the development of comprehensive health information systems to inform national research priorities; WHO guidelines on research capacity-strengthening, including indicators for measuring progress, have been developed and are being used; Develop and use standardized indicators to enable selfreporting of the performance of national health research systems and monitor global progress; Advocate for strong NHRS WHO reports progress periodically on national research capacity and activities through its governing bodies and information databases; Facilitate technical assistance to support the strengthening of national health research systems; Develop institutional capacity, regional and global networks, involvement of WHO Collaborating Centres, to report and share good practice; Networks of researchers and communities of practice are actively exchanging experiences and identifying good practices in strengthening research capacity; WHO’s research capacity-strengthening efforts incountry are aligned with country needs, resulting in higher-quality, better-coordinated research activities. Maximize the impact of research capacitystrengthening efforts through improved alignment of WHO’s research programmes and activities. 15 | WHO Strategy on Research for Health | January 2009 All countries have national health research strategies Standards Working with Member States and What success will look like: partners, WHO will: Develop a systematic method for selecting, developing, implementing and evaluating new standards and norms in line with priorities in research for health; Develop norms and standards, in line with the guiding principles of this strategy, for best practice in the management and use of research; Public support and trust for health and medical research is strengthened; WHO has implemented an improved method for selecting, developing, implementing and evaluating its work on norms and standards related to research; Greater awareness, acceptance, implementation and compliance with standards for the management and use of research leading to an improved quality, efficiency, transparency, accountability and equity in the research process; Improved acceptance and compliance with ethical principles in the conduct of research, and standards established for accreditation of ethics committees; Registration of clinical trials according to WHO standards is adopted by all countries. Which standards? Continue to facilitate the development of and set standards for publicly accessible registries of clinical trials; Engage in technical cooperation with Member States to enable them to adapt, implement and monitor adherence and compliance to the norms and standards for research. 16 | WHO Strategy on Research for Health | January 2009 Better awareness, acceptance & compliance Translation Working with Member States and partners, WHO will: Identify promising translation activities, promote their use to support decision-making based on the best available research evidence; Promote the use of effective technology transfer models and the evaluation of promising models to support the timely creation of new products and services in Member States; Identify best translation activities What success will look like: Decision-makers act as informed consumers of research; Researchers are more responsive to the demand side; institutional mechanisms are in place for capturing and sharing lessons learned from research on the demand for research and how evidence is used in policy and practice at country level; Research to understand the translation of evidence into policy and practice is in place and recognized; internationally agreed standards are created and widely applied for the collection, storing and sharing of health informatics; Research informs policy & policy informs research repositories inclusive of WHO research literature are Work towards the creation of and compliance with international standards on health informatics for research; Develop, strengthen and evaluate mechanisms for the systematic development of evidence summaries and guidance for citizens, patients, clinicians, managers and policy-makers in Member States; Systematically analyze barriers and encourage the development or modification of existing mechanisms to promote greater access to research results; Reliable, relevant, appropriate and timely information is freely available to both producers and users of research in a format and language they understand; WHO plays a more prominent role in identifying effective health interventions and strategies, and promoting their implementation in Member States. Develop and articulate a WHO position on open access to research outputs. 17 | WHO Strategy on Research for Health | January 2009 established, well populated, regularly updated and well used; VISION decisions and actions to improve health and enhance health equity are grounded in evidence from research. MISSION WHO, Member States and partners work together to harness knowledge, science and technology to produce research evidence and tools to improve health CAPACITY Champion research that addresses priority health needs Support the development of robust national health research systems STANDARDS TRANSLATION Promote good research practice Strengthen links between research, policy and practice ORGANIZATION Strengthen the research culture across WHO WHO STRATEGY ON RESEARCH FOR HEALTH 5 Goals PRIORITIES A framework for research for health priorities Research on neglected priority needs Translation and delivery of the solution 19 | WHO Strategy on Research for Health | January 2009 Research and Training in Tropical Diseases (TDR) TDR Research business lines Lead discovery for drugs (screening/optimizing drug leads for tropical diseases Neglected priority needs • TDR Selected drug development and field interventions (TB/HIV, helminths, other NTD ) • Innovate vector control interventions Translation and delivery of the solution • Innovation and access in diagnosis • Evidence for antimalarial policy and access • Visceral leishmaniasis elimination • Integrated community-based interventions 20 | WHO Strategy on Research for Health | January 2009 Research strategy on Foodborne Disease Burden, its impact and on effective interventions Priority No 1No global burden of FBD estimates currently exist Priority No 2 Determinants of burden partially known but not synthesized Research on neglected priority needs Priority No 3 Food Safety standard setting, control and interventions are well described but impact often not known 21 | FOS Translation and delivery of the solution Solutions fairly well described but not always evidence-based – this might have to be revisited after strategy has been executed in its entirety Priority No 4 Solutions often not linked to evidence – this requires re-examination and new application WHO Strategy on Research for Health | January 2009 Links to Bamako and the Global Strategy Plan of Action (from the IGWG) WHO Global Strategy Plan of Action – No. elements Strategy Priorities Bamako Ministerial Forum Call for Action by Ministers 1- priorities Set priorities 2 - cooperation 2% health budget for research 7- sustainable funding Capacity 3 – capacity R&D for products Build institutional capacity 2 - cooperation Regional Cooperation Build capacity in science through education Standards 6 – ethical review, QA Clinical trials Open access to research outputs, products and technologies Translation 2 – strengthen national health research Promote translation - 5% of funding to support this Research in all policies 22 | WHO Strategy on Research for Health | January 2009 Implementation Approval by Member States at EB and WHA in 2009 Review, discussion of governance, financing A strategy for implementation; detailed plan needed Decentralized implementation-key role for Regional Offices to implement strategy after alignment with agendas, plans and strategies Incorporation into work plans, country cooperation strategy 23 | WHO Strategy on Research for Health | January 2009 Evaluation Evaluation framework developed to give impact-focussed approach for assessing achievement of vision, mission and goals Framework components: inputs/activities, outputs, outcomes and impacts Indicators for each component defined for tracking purposes Report on progress to governing bodies in 2012 24 | WHO Strategy on Research for Health | January 2009 "Through the research strategy, what can WHO do to help democratize R&D so that knowledge is not just for the rich and is equitably used to improve health for all peoples?" Dr Anarfi Asamoa-Baah WHO Deputy Director-General November, 2007 25 | WHO Strategy on Research for Health | January 2009 Many thanks Further information can be obtained from: SharePoint: http://www.who.int/rpc/research_strategy Robert Terry Project Manager - WHO Research Strategy, Research Policy & Cooperation (RPC/IER), World Health Organization Email: terryr@who.int Tel No : +41 22 7912632 Mob No:+41 792446091 Acknowledgements The WHO strategy on research for health was developed with support from : The Bill and Melinda Gates Foundation The Wellcome Trust http://www.who.int/rpc 26 | WHO Strategy on Research for Health | January 2009 The Department of Health, UK