Chapter 17 – Part 4 Intestines Watch an overview of the intestines and abdominal cavity. This video is graphic as it uses a cadaver. https://www.youtube.com/watch?v=EJt4YDPL pzE&feature=related Coverings: 1. Greater Omentum a "curtain-like" membrane that covers the intestines, stores fat and lays like a drape 2. Mesentery • suspends portions of the small intestine from the posterior abdominal wall Small Intestine – 3 parts start at the pyloric sphincter The Duodenum first part of the small intestine. Food, still mixed with gastric juice is squirted into it from the stomach. The food is now a semi liquid, highly acidic mush. It needs to be neutralized and digestion needs to be continued… • Small, soluble food molecules are absorbed through the wall of the small intestine • To absorb food molecules efficiently the small intestine has three main adaptations……. 1. Large Surface Area The small intestine is very long -6m long The inner surface on the intestine is folded Each cell is covered with microvilli increasing the surface area in contact with digested food will increase absorption (up to 60 times more absorption) Wall of small intestine ‘finger-like folds in the surface of the small intestine’ (Singular – villus) Intestinal villi - increase surface area to absorb nutrients, connect to vessels 2. Thin Wall • Each villus has an extremely thin wall -only one cell thick -rapid absorption • electrolytes and water • through diffusion, osmosis, and active transport • absorbed into blood 3. Good Blood Supply • Each villus is supplied with blood vessels to receive the absorbed foods -glucose/amino acids/vitamins/minerals are absorbed into blood capillaries -products of fat digestion absorbed into lacteal • Homework – do this animation. Make sure you digest a number of different types of foods. Note how they are digested differently. http://kitses.com/animation/swfs/digestion.swf Secretions of Small Intestine • peptidase – breaks down peptides into amino acids • sucrase, maltase, lactase – break down disaccharides into monosaccharides • lipase – breaks down fats into fatty acids and glycerol • enterokinase – converts trypsinogen to trypsin • somatostatin – hormone that inhibits acid secretion by stomach • cholecystokinin (cck) – hormone that inhibits gastric glands, stimulates pancreas to release enzymes in pancreatic juice, stimulates gallbladder to release bile • secretin – stimulates pancreas to release bicarbonate ions in pancreatic juice Enzyme Summary Enzyme Substrate Product Where it is produced Where it acts Pancreas Duodenum Amylase Amino Acids Fat Small intestine Movements of the small intestine • mixing movements • peristalsis – pushing movements • segmentation – ringlike contractions • overdistended wall triggers peristaltic rush resulting in diarrhea Large Intestine Cecum Appendix Colon (4 parts) Cecum Ascending Transverse Descending Sigmoid Rectum Anus Function of Large Intestine Secretes mucus, reabsorbs water and electrolytes, contains bacteria to aid in digestion (intestinal flora) Mass Movements (defecation) - removes undigested food The main job is WATER REABSORPTION... Large Intestinal Wall Simple columnar epithelium Egestion Any indigestible food (e.g. fiber) passes into the large intestine (colon). Water is absorbed back into the body. Where has this water come from? The food becomes a solid waste called feces. Feces are stored in the rectum and removed through the anus. This removal is called EGESTION. Movements • slower and less frequent than those of small intestine • mixing movements • peristalsis • mass movements usually follow meals Everybody Poops Feces • water • electrolytes • mucus • bacteria • bile pigments altered by bacteria provide color • smell produced by bacterial compounds How to Make Fake Poop... LABEL THIS! Practice makes perfect. Click to access all the answers. 1. esophagus 2. liver 3. stomach 4. pyloric sphincter 5. duodenum 6. pancreas 7. jejunum 8. ileum 9. cecum 10. appendix 11. ascending colon 12. descending colon 13. sigmoid colong 14. anus Microflora of the Gut IBS - Irritable Bowel Syndrome – normal structure of bowel Crohn’s Disease - autoimmune Appendicitis Hernia intestines poke through abdominal muscles Celiac disease foods containing gluten (protein), immune system responds by damaging or destroying villi Without healthy villi, a person becomes malnourished, no matter how much food one eats. Colon Cancer Colonoscopy is a screening technique to detect cancer. See Katie Couric's Colonoscopy