Chapter 1: The Human Body: An Orientation
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An Overview of Anatomy
Anatomy
The study of the structure of the human body
Physiology
The study of body function
* Please understand the difference between structure and function
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An Overview of Anatomy
Anatomical terminology
Based on ancient Greek or Latin
Provides standard nomenclature worldwide
Branches of anatomy
Gross anatomy
Microscopic anatomy (histology)
Surface anatomy – need to know what a normal body looks like to identify anomalies, locate veins for venipuncture, etc.
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An Overview of Anatomy
Other branches of anatomy
Developmental anatomy-structural changes of aging
Embryology – study of development of fetus
Pathological anatomy (pathology)- study of disease
Radiographic anatomy- study of anatomy using radiographic imagery, CT, MRI, PET, ultrasound
**Why are there so many different imaging techniques?
Please understand what each technique images
Functional morphology
Microscopic – anatomy of structures using various microscopic instruments.
Histology – study of tissues
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The Hierarchy of Structural Organization
Chemical level – atoms form molecules
Cellular level – cells and their functional subunits
Tissue level – a group of cells performing a common function
* Please think about the fact that our bodies are made of atoms, the same thing as rocks, plants, stars and comets!
By understanding the nature of specific atomic structures, you will become aware of how chemistry provides the basis of living systems. Chemistry is a simple matter of balancing electromagnetic charges! You can move a piece of metal by bringing a magnet nearby…movement!
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The Hierarchy of Structural Organization
Organ level – a discrete structure made up of more than one tissue. e.g. the heart is made of muscle (obviously), connective tissue, nerves and epithelial tissue (valves)
Organ system
– organs working together for a common purpose
Organismal level
– the result of all simpler levels working in unison
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The Hierarchy of Structural Organization
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Figure 1.1
Systemic v. Regional Anatomy
Systemic – study of anatomy by system
Regional – study of anatomy by region
Most students use a combination of regional and systemic study
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Integumentary System
Forms external body covering
Protects deeper tissues from injury
Synthesizes vitamin D
Site of cutaneous receptors
(pain, pressure, etc.) and sweat and oil glands
http://www.youtube.com/watch?v=no_XRnoNGfE
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Skeletal System
Protects and supports body organs
Provides a framework for muscles
Blood cells formed within bones
Stores minerals
http://www.youtube.com/watch?v=vya4wpS2fgk
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Muscular System
Allows manipulation of environment
Locomotion
Facial expression
Maintains posture
Produces heat
http://www.youtube.com/user/bigsmokes62#p/a/u/
1/RsWNyqnHQ2I
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Nervous System
Fast-acting control system
Responds to internal and external changes
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Endocrine System
The Endocrine system works as a regulatory messaging system similar to the nervous system
Remember: cells are isolated! They don’t know what to do unless they are told what to do and either the nervous system or then endocrine system tells them what to do!
Glands secrete hormones that regulate
Growth
Reproduction
Nutrient use
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Cardiovascular System
Blood vessels transport blood
Carries oxygen and carbon dioxide
Also carries nutrients and wastes
Heart pumps blood through blood vessels
Blood vessels are merely the plumbing which brings water, gases and nutrients to the individual cells. It is similar to a city’s water system. The heart is the pump just like our residential water has a pump station so that we have water pressure!
Again, the cells are (mostly) fixed and isolated and they rely on the intelligence of the monitoring systems of the body
(the nervous system) to provide it’s needs.
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Lymphatic System/Immunity
Picks up fluid leaked from blood vessels
Disposes of debris in the lymphatic system
Houses white blood cells (lymphocytes)
Mounts attack against foreign substances in the body
The lymphatic system is a highly understudied system in the body. It is in fact one of the most important systems of the body! Without proper functioning of this system, we would die!
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Lymphedema
The lymphatic drainage of the leg is impaired and the fluid collects in the limb causing it to swell. The cells are improperly nourished and will become diseased
.
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Respiratory System
Keeps blood supplied with oxygen
Removes carbon dioxide
Gas exchange occurs through walls of air sacs in the lungs
This is a simple system to understand but it also functions in the acid-base balance of the physiology
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Digestive System
Breaks down food into absorbable units
Indigestible foodstuffs eliminated as feces
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Urinary System
Eliminates nitrogenous wastes
Regulates water, electrolyte, and acid-base balance
The cells of our body (all 70 trillion of them!) require an exact environment to survive. The urinary system along with the lymphatic system provides this environment directly.
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Why do we have body systems?
What do they provide?
Do we need all of them?
How did they come about?
What is homeostasis?
How does each system contribute to homeostasis?
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Male & Female Reproductive Systems
Overall function is to produce offspring
Testes produce sperm and male sex hormones
Ovaries produce eggs and female sex hormones
Mammary glands produce milk
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Gross Anatomy – An Introduction
Anatomical position – a common visual reference point
Person stands erect with feet together and eyes forward
Palms face anteriorly with the thumbs pointed away from the body
Directional terminology
– refers to the body in anatomical position
Standardized terms of directions are paired terms
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Gross Anatomy – An Introduction
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Figure 1.3
Gross Anatomy – An Introduction
Directional terms
Regional terms – names of specific body areas
Axial region
– the main axis of the body
Appendicular region
– the limbs
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Orientation and Directional Terms
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Table 1.1 (1 of 3)
Orientation and Directional Terms
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Table 1.1 (1 of 3)
Orientation and Directional Terms
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Table 1.1 (2 of 3)
Orientation and Directional Terms
May be used on exams!
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Table 1.1 (3 of 3)
Regional Terms
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Figure 1.4a
Regional Terms
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Figure 1.4b
Body Planes and Sections
Coronal (frontal) plane
Lies vertically and divides body into anterior and posterior parts
Median (midsagittal) plane
Specific sagittal plane that lies vertically in the midline
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Body Planes and Sections
Transverse plane
Runs horizontally and divides body into superior and inferior parts
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Figure 1.5
Oblique Section Through the Trunk
Oblique Plane
D ivides the body at an angle between the horizontal and vertical planes
Figure 1.6
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Banana Sectioned into Planes
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Figure 1.7
The Human Body Plan
Tube-within-a-tube
Bilateral symmetry
Dorsal hollow nerve cord
Notochord (primative supporting rod) and vertebrae
Segmentation
Pharyngeal pouches (gills!)
Post-anal tail (at some point in development)
Characteristics common to all vertebrate
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Basic Human Body Plan and Structures
Shared with all Vertebrates
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Figure 1.8a
Basic Human Body Plan and Structures
Shared with all Vertebrates
May be used on exams!
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Figure 1.8b
Basic Human Body Plan and Structures
Shared with all Vertebrates
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Figure 1.8c
Body Cavities and Membranes
Dorsal body cavity
Cranial cavity
Vertebral cavity
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Body Cavities and Membranes
Ventral body cavity
Thoracic cavity – divided into three parts
Be able to describe it’s location and contents! Anterior-sternum, posterior-thoracic vertebrae, lateral-lungs, superior-1 st rib, inferior-diaphragm
Two lateral parts each containing a lung surrounded by a pleural cavity
Mediastinum
– lies between the lungs and contains the heart surrounded by the pericardial sac, the trachea, the esophagus, the superior vena cava, the inferior vena cava and various nerves. This is an anatomically important area.
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Body Cavities and Membranes
Ventral cavity (continued)
Abdominopelvic cavity – divided into two parts
Abdominal cavity – contains the liver, stomach, kidneys, and other organs
Pelvic cavity
– contains the bladder, some reproductive organs, and rectum
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Body Cavities and Membranes
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Figure 1.9a
Body Cavities and Membranes
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Figure 1.9b
Body Cavities and Membranes
Serous cavities
– a coelomic cavity, like that enclosed by the pericardium, peritoneum, or pleura, not communicating with the outside body, and whose lining membrane secretes a serous fluid. Pleura (enclosing lungs), pericardium(enclosing heart), and peritoneum(enclosing most of abdominal organs but specifically NOT the kidneys!)
Parietal serosa – outer wall of the cavity
Visceral serosa covers the visceral organs
*Always remember the difference between parietal and visceral…visceral is ALWAYS against the organ(s)
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Body Cavities and Membranes
The purpose of the serosal membranes is to reduce friction so that viscera (organs) move freely and stay cool.
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Figure 1.10a, b
Body Cavities and Membranes
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Figure 1.10c
Body Cavities and Membranes
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Figure 1.10d
Body Cavities and Membranes
Other cavities
Oral cavity
Nasal cavity
Orbital cavities
Middle ear cavities
Synovial cavities
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Other Body Cavities
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Figure 1.11
Abdominal Regions and Quadrants
Abdominal regions divide the abdomen into nine regions
Abdominal quadrants divide the abdomen into four quadrants
Right upper and left upper quadrants
Right lower and left lower quadrants
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Abdominal Regions
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Figure 1.12a, b
Abdominal Quadrants
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Figure 1.12c
Microscopic Anatomy
Microscopy – examining small structures through a microscope
Light microscopy illuminates tissue with a beam of light (lower magnification)
Electron microscopy uses beams of electrons
(higher magnification)
TEM transmission electron microscopy will always be sharper than light microscope
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Microscopic Anatomy
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Figure 1.13
Microscopic Anatomy
Preparing human tissue for microscopy
Specimen is fixed (preserved) and sectioned
Specimen is stained to distinguish anatomical structures
Acidic stain
– negatively charged dye molecules
Basic stain
– positively charged dye molecules
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Microscopic Anatomy
Scanning electron microscopy
Heavy metal salt stain – deflects electrons in the beam to different extents
Artifacts
Minor distortions of preserved tissues
Not exactly like living tissues and organs
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Clinical Anatomy – An Introduction to Medical
Imaging Techniques
X ray – electromagnetic waves of very short length
Best for visualizing bones and abnormal dense structures
Figure 1.14
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Clinical Anatomy – An Introduction to Medical
Imaging Techniques
Variations of X ray
Fluoroscope
– images are viewed on a fluorescent screen
Allows viewing of internal organs as they move
Cineradiography
– uses X-ray cinema film to record organ movements
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Advanced X-Ray Techniques
Computed (axial) tomography (CT or CAT) – takes successive X rays around a person's full circumference
Translates recorded information into a detailed picture of the body section
This technique receives information only from transverse planes and adds them up to form a 3D image.
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Advanced X-Ray Techniques
Digital subtraction angiography (DSA) imaging provides an unobstructed view of small arteries
DSA is often used to identify blockages of arteries that supply the heart or brain
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Advanced X-Ray Techniques
Positron emission tomography (PET) – forms images by detecting radioactive isotopes injected into the body
Sonography (ultrasound imaging) – body is probed with pulses of high-frequency sound waves that echo off the body's tissues
Imaging technique used to determine the age of a developing fetus
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Advanced X-Ray Techniques
Magnetic resonance imaging (MRI) – produces high-quality images of soft tissues
Distinguishes body tissues based on relative water content
Figure 1.19a
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