By Matthew Morgan, Andrew Lomanto, Taylor Stauffer
http://www.kiwifamilies.co.nz/T
opics/Support+Groups/Illness/
Cystic+Fibrosis.html
What is Cystic Fibrosis
-A hereditary disorder
-Makes glands secrete a
sticky mucus which
clods the pancreas,
liver, and intestines .
-Infection of the lungs
http://www.nlm.nih.gov/medlineplus/ency/imagepages/18135.htm
Cystic Fibrosis Inheritance
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Both parents can carry the gene
Occurs right after birth
Child has 25% chance of getting Cystic
Fibrosis if both parents are heterozygous
carriers and 50% of being a carrier
Abnormal recessive gene
Both parents need to be carriers in order
for the off spring to inherit Cystic Fibrosis
Cystic Fibrosis Inheritance Punnet
Square
http://www.csupomona.edu/~biology/bio110/inherit/genes.html
Cystic Fibrosis Frequency

1/25 of all Caucasians carry this disease
http://www.greatstrides.com.au/images/
nebulisertreatment.jpg
http://breathe4tomorrow.org/wpcontent/uploads/2008/12/alexus.jpg
Symptoms and Effects
Symptoms
-
Effects
Very salty skin
Frequent coughing
Wheezing
Impaired growth (due to lack of
nutrition)
Greasy feces
http://www.exposay.com/wee
man-the-world-premiere-ofjackass-numbertwo/p/4630/65/
-Because of sticky mucus, the
pancreas is clogged, which
impairs digestive enzyme flow
to intestines, which minimizes
the patient, potential to digest
food and harvest nutrients
-Sticky mucus also creates a
layer around the lungs makes
it harder for patient to breath,
especially during cardio
activates
-Average life expectancy of
persons with Cystic Fibrosis:
about 30 years
How is it Diagnosed?
Usually discovered in early childhood
 Simple procedure, where the patient is
tested for excessive levels of sodium
chloride in their sweat
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http://www.baynews9.com/article/news/2011/
january/192524/New-hope-for-people-livingwith-cystic-fibrosis
How is this Disease Treated?
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It is possible to extract the pancreas, to
overcome the lack of digestive enzyme flow
Daily back slapping is in order, because it
helps break up the mucus.
Gene Therapy- It is possible to inject a
normal, healthier gene into the patient. This
therapy has had high hopes from scientists,
but has shown no positive results yet.
Currently, there are a few known antibiotics
that have proven to increase one’s life
expectancy
Is There a Cure?

There is no known cure, but scientists
everywhere are striving to produce one
for this disease. There is a foundation for
this disease, which raises money for aid to
the current patients, and for finding a
cure in the near future
SMaRT Therapy
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A type of gene therapy, which takes
advantage of the need to remove introns.
This makes a functional mrna, so genes
will continue to reduce possibility of the
patient’s child getting the disease
Works Consulted

“About Cystic Fibrosis.” Cystic Fibrosis Foundation. Cystic Fibrosis
Foundation, n.d. Web. 28 Jan. 2011. <http://www.cff.org//>.
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“Cystic Fibrosis.” Encyclopedia of Genetics. Ed. Don P. Dawson. Vol. 1.
Pasadena, CA: Salem Press Inc., 2004. 195-198. Print.
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“Cystic Fibrosis.” Genetic Science Learning Center. Learn Genetics , 28 Jan.
2011. Web. 28 Jan. 2011.
<http://learn.genetics.utah.edu/////ex.html>.

Jacoby, David R., and Robert M. Youngson. “Cystic Fibrosis.” Encyclopedia of
Famliy Health. Ed. Joyce Tavolacci. Vol. 4. Tarrytown, NY: Marshall
Cavendish, 2005. 448. Print.

“What is Cystic Fibrosis.” TOBI. TOBI, 2011. Web. 28 Jan. 2011.
<http://www.tobitime.com///cystic_fibrosis.jsp?utm_medium=cpc&utm
_content=about+cystic+fibrosis&utm_source=MSN&utm_campaign=Tob
i_Unbr anded_2.25.10>.