NINTH TECHNICAL ADVISORY GROUP AND NATIONAL TB PROGRAMME MANAGERS
MEETING FOR TB CONTROL IN THE WESTERN PACIFIC REGION
Manila, Philippines, 9-12 December 2014
A/Prof. Nguyen Viet Nhung, MD., PhD
Director, National Lung Hospital
Manager, National TB control Program
Viet Nam

Liz Corbett
Afranio Kritski
Melvin K. Spigelman
Alison Kraigsley
Viet Nhung Nguyen
Joseph Cavanaugh
Nadia Khelef
Ajaya M.V. Kumar
Tom H.M. Ottenhoff
Abdul Ghaffar
Anna Scardigli
Tom Evans
Knut Lönnroth

Aspect
Curent situation
DO BETTER AND DO MORE
Global
There are some models in several countries: Brazil, Viet Nam, India,
Indonesia, …
Multi-country academic networks
WHO Training package for TB control, but not yet for TB research training
Country (LMIC)
There are available TB research in all countries, but still:
Lack of information about Research (Capacity, HR, opportunity, …)
Lack of effective models for Capacity building
Lack of coordination of all existing, ongoing research in countries (projects, institution, researchers, resources)
 overlap, no translation into practice, waste …
There are various level of TB research: R&R, data management, basic  implementation research
The needs There are Roadmap and OR priority
Toolkit for evaluation: SWOT analysis
Guidance for create research demand for the new strategy
A new program, model for TB research training
TA for TB research
Mapping key institutions
Solutions Guideline / recommendation
Framework for capacity building for TB Research
Model and piloting model
Country TB Research Agenda
SWOT analysis on Tb research
Prioritizing the gaps
Planning to fill the gaps
Mapping, inventory all available, ongoing project, HR, partners
True partnership for TB research
Coodination and ownership: MoH, NTP, MoEdu, …
NTP needs to be the core
Identify the priority researches that should be focus of the country (basic  implementation research)
Establish strategic plan of TB research in the national strategy for TB control as the whole (TB research agenda)
Create a leadership, partnership for implementing the plan for better coordination and collaboration

Aspect Global Country (LMIC)
1 year Establish a ad hoc WG & ToR based in WHO
- Define needs for 1 year deliverables
- Identify key players (TB Programme,
TDR, Alliance, the Union, …)
- Guide for conducting in-country mapping and situational analysis
- Develop participatory workshop facilitator guides for NTP to support comprehensive research strategy generation
- Share training and research materials
- Encourage in-country mapping and situational analysis with needs assessment of TB activities and
NTP capacity to conduct research in all countries
- Develop clear plan for comprehensive National TB
Research Agenda and capacity building strategy (inc
OR, basic etc)
- Example Research Strategy plans from key countries
- Pathfinders
- Viet Nam, Kenya, BRICS, Uganda, Malawi
- Invite applications from all countries
- Ask regional offices to nominate
- Repository for materials
- Hold workshop for exchange of ideas and lessons learnt between key players
- In-country regulatory review to define functionalities, timelines and information for international collaborators in TB and broader research capacity building initiatives
- Best practice country examples to share learning points and draw guidance
- Initiate consideration of regional harmonization plans
- Initiate consideration of regional research networking plans
- Include critical assessment meetings in regional meetings and International Union Conferences

Aspect Global Country (LMIC)
5 years
10 years
• Researchers toolkit, databases, and data sharing
• Established global research movement with hubs regional
• Expansion of TB research network in regions and countries
• All high burden countries have a Strategic research and capacity building plan
• Regional networks established
• Individual and multicountry studies providing results
• OR funds available from Global Fund are fully utilized
• Funding sources diversified and increased, including in-country investment
• Supportive research environment and regulatory processes
Researchers toolkit, databases, and data sharing
Scale up TB research network in countries, regions and global
• Capacity to evaluate TB epidemic and control interventions
• Established leadership in comprehensive TB research platform from (formerly) high to know how to achieve the TB control Goal. burden countries
• Clear examples of contribution of national research to local control efforts

Framework Level Funding resources
Gov’t
Government /
MoH
National Strategy to 2020 with vision 2030: Optimize the application of current and new technologies, approaches in TB detection, diagnosis, treatment and prevention
National Program National Strategic Plan for TB control 2015-2020
Objective 4 (of 4). To sustain and promote monitoring, evaluation and surveillance of the TB epidemic and control while applying new technologies and approaches in TB control by routine data, surveys and researches.
- 16 projects in agenda 2015-2020 with
Partnership
Gov’t and partners
National Lung Hospital / NTP: Core partner
TB and lung disease research coalition: MoH, MOST, Academy,
University, Institution.
International partners: KNCV, WHO, UCSF, Sydney University,
WMRI, LSHTM, …
GFATM,
AUSAID,
USAID,
CDC,
WHO,
Projects,
…
Provincial program and other institution
R&R, case based, web based surveillance system
Research Project implementation: capacity building on needs
Promoting younger researchers

4.1. Further development and updating of both paper based and electronic R&R systems (VITIMES and e-TB manager) to support the program measure indicators for IC, Childhood TB, PPM,
Community engagement, Pharmacovigilance and new drugs and regimens initiative, equipment maintenance etc.
4.2. Develop and implement data quality assurance and security system for protection of electronic records.
4.3. Identify new gaps from the feedback of M&E and supervision visits and strengthening health facilities to fulfil the needs for PPM and PMDT scale up.
4.4. Strengthen research partnership with universities in Vietnam
4.5. Analysis of population access to TB services per province and population groups
4.6. Enhanced surveillance for risk group identification and follow-up of yield attributable to active and passive case finding in each risk group
4.7. Operational research to underpin and support the stepwise introduction of new regimens for
TB and/or MDR, including pharmacovigilance
4.8. Continuation of the STREAM trial in HCMC, ACT3 in Ca Mau (Community based genExpert screening for TB), TBTC in Ha Noi (clinical trials for TB drugs and regimens), GeneTB .
4.9. Operational research to support and evaluate new tools (mHealth, CAD4TB), in public and private sector
4.10. Studies on elimination of TB in Vietnam , modeling of the epidemic in collaboration with the
London School of Hygiene & Tropical Medicine (LSHTM), piloting interventions in preparation of scenario’s for TB “elimination ”
4.11. National Prevalence survey of Tuberculosis (2015-2017)
4.12. 5 th National Drug Resistant Survey (2015-2016)
4.13. Studies related to health financing (Vietnam transitioning towards full coverage of health insurance, paying for TB diagnosis and treatment)
4.14. Study on fluoroquinolone and pyrazinamid resistance among new patients
4.15. Sentinel survey for TB in KAPs
4.16. Mortality and fatality of TB in sentinel areas