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2015 ANNUAL DATA REPORT

V

OLUME

2: E

ND

-S

TAGE

R

ENAL

D

ISEASE

Chapter 9: Cardiovascular Disease in Patients With ESRD

Figure 9.1 Causes of death in ESRD patients, 2013

Data Source: Reference Table H12. Abbreviations: AHD, atherosclerotic heart disease; AMI, acute myocardial infarction;

CHF, congestive heart failure; CVA, cerebrovascular accident.

Vol 2, ESRD, Ch 9 2

Figure 9.2 Prevalence of cardiovascular diseases in ESRD patients, by treatment modality, 2013

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients at all ages, with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to

December 31, 2010, ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2012. Abbreviations: AFIB, atrial fibrillation; AMI, acute myocardial infarction; ASHD, atherosclerotic heart disease; CHF, congestive heart failure; CKD, chronic kidney disease; CVA/TIA, cerebrovascular accident/transient ischemic attack; CVD, cardiovascular disease; PAD, peripheral arterial disease;

SCA/VA, sudden cardiac arrest and ventricular arrhythmias.

Vol 2, ESRD, Ch 9 3

Figure 9.3 Prevalence of cardiovascular diseases in ESRD patients, by age, 2013

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients at all ages, with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to

December 31, 2010, ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2012.Abbreviations: AFIB, atrial fibrillation; AMI, acute myocardial infarction; ASHD, atherosclerotic heart disease; CHF, congestive heart failure; CKD, chronic kidney disease; CVA/TIA, cerebrovascular accident/transient ischemic attack; CVD, cardiovascular disease; PAD, peripheral arterial disease;

SCA/VA, sudden cardiac arrest and ventricular arrhythmias.

Vol 2, ESRD, Ch 9 4

Table 9.1 Prevalence of cardiovascular diseases & procedures in ESRD patients, by treatment modality, age, race, & sex, 2013

% Patients

45-64 65-74 75+ White

Blk/Af

Am

Other Male Female

# Patients

Overall 0-21 22-44

Cardiovascular Comorbidities a

Atherosclerotic heart disease (ASHD)

Hemodialysis

Peritoneal dialysis

147,373

11,180

Transplant 23,465

Acute myocardial infarction (AMI)

40.8

32.0

22.3

2.5

0.9

0.4

Hemodialysis

Peritoneal dialysis

147,373

11,180

Transplant 23,465

Congestive heart failure (CHF)

13.7

11.2

7.3

0.0

0.5

0.0

Hemodialysis

Peritoneal dialysis

147,373

11,180

37.2

25.2

10.7

6.5

Transplant 23,465 18.7

2.2

Cerebrovascular accident/transient ischemic attack (CVA/TIA)

15.0

11.3

2.8

1.4

Hemodialysis

Peritoneal dialysis

147,373

11,180

Transplant 23,465

Peripheral artery disease (PAD)

Hemodialysis

Peritoneal dialysis

Transplant

Atrial fibrillation (AFIB)

147,373

11,180

23,465

Hemodialysis

Peritoneal dialysis

Transplant

147,373

11,180

23,465

7.8

30.0

20.7

13.9

19.5

14.1

12.4

0.6

10.3

5.6

0.7

0.7

0.0

0.0

(Continued on next slide)

15.6

11.9

6.1

5.4

4.1

2.3

22.4

16.0

6.9

16.3

10.7

5.0

5.0

3.8

1.8

5.5

5.5

2.4

36.8

31.7

19.3

12.5

11.1

6.8

33.7

23.8

15.5

12.5

9.9

6.2

28.5

20.7

12.7

14.5

10.4

8.3

49.7

44.0

36.8

16.5

15.6

11.2

42.2

32.0

29.1

19.0

16.6

13.0

34.6

27.7

21.3

23.3

21.0

22.4

52.1

49.1

43.2

17.4

17.2

13.5

45.9

35.5

39.5

20.3

17.4

17.5

34.9

26.8

25.0

32.0

32.1

34.7

45.1

35.4

24.0

15.1

12.6

7.9

37.8

25.5

19.1

15.0

12.0

8.2

31.2

22.3

14.6

23.2

16.4

13.9

36.0

25.7

19.0

12.1

9.0

6.1

37.1

25.6

18.8

15.4

10.7

7.5

29.3

18.4

13.0

15.3

9.8

9.3

38.4

27.5

18.3

12.1

8.1

6.1

32.0

21.3

13.8

13.0

7.6

5.2

23.9

15.2

10.2

17.2

11.2

9.7

40.9

36.5

24.0

13.7

12.8

7.8

35.4

27.2

18.9

13.5

11.0

7.6

29.9

22.3

15.0

19.7

16.8

13.6

40.7

27.5

19.7

13.6

9.6

6.5

39.4

23.3

18.4

16.9

11.6

8.1

30.0

19.0

12.3

19.2

11.5

10.5

Vol 2, ESRD, Ch 9 5

Table 9.1 Prevalence of cardiovascular diseases & procedures in ESRD patients,

by treatment modality, age, race, & sex, 2013 (Continued)

% Patients

# Patients

Overall 0-21 22-44 45-64 65-74 75+ White

Blk/Af

Am

Other Male Female

Cardiac arrest and ventricular arrhythmias (SCA/VA)

Hemodialysis

147,373

Peritoneal dialysis

11,180

Transplant

Cardiovascular Procedures b

23,465

7.3

6.0

4.0

0.4

2.3

0.2

3.8

3.2

1.0

Revascularization – percutaneous coronary interventions (PCI)

Hemodialysis 60,125

5.3

0.0

Peritoneal dialysis 3,578 6.2

0.0

Transplant 5,228 5.2

0.0

Revascularization – coronary artery bypass graft (CABG)

4.8

5.4

5.6

6.9

5.7

3.2

6.3

6.1

7.0

8.8

7.9

7.0

5.4

7.3

4.4

8.1

8.6

8.8

4.0

5.3

2.6

7.2

6.1

4.2

5.6

6.8

5.4

Hemodialysis 60,125

1.8

0.0

2.2

2.5

1.8

0.7

1.7

Peritoneal dialysis 3,578

2.6

0.0

2.9

2.8

2.8

2.0

2.7

Transplant 5,228

2.0

0.0

2.0

2.5

1.7

1.7

2.1

Implantable cardioverter defibrillators & cardiac resynchronization therapy with defibrillator (ICD/CRT-D)

54,775 0.8

0.0

0.9

0.9

0.9

0.5

0.8

Hemodialysis

Peritoneal dialysis

Transplant

2,818

4,384

1.0

1.0

0.0

0.0

0.3

0.0

1.0

1.3

1.1

1.0

1.2

0.7

0.9

1.1

7.5

6.3

3.8

4.7

5.3

4.5

1.7

2.5

1.5

0.7

1.2

0.7

6.0

3.6

3.5

6.3

3.1

5.5

2.4

2.2

3.1

0.8

0.6

0.5

7.5

6.7

4.5

5.4

6.0

5.4

2.0

3.4

2.0

1.0

1.1

1.3

0.4

0.8

0.4

5.2

6.4

4.8

1.4

1.6

2.0

6.9

5.3

3.4

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients at all ages, with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2012. Abbreviations: AFIB, atrial fibrillation; AMI, acute myocardial infarction; ASHD, atherosclerotic heart disease; Af Am, African American; Blk, black; CABG, coronary artery bypass grafting; CHF, congestive heart failure; CKD, chronic kidney disease;

CVA/TIA, cerebrovascular accident/transient ischemic attack; CVD, cardiovascular disease; ICD/CRT-D, implantable cardioverter defibrillators/cardiac resynchronization therapy with defibrillator devices; PAD, peripheral arterial disease; PCI, percutaneous coronary interventions; SCA/VA, sudden cardiac arrest and ventricular arrhythmias. a The denominators for all cardiovascular comorbidities are patients described above by modality. b The denominators for PCI and CABG are patients with ASHD by modality. The denominator for ICD/CRT-D is patient with CHF by modality.

Vol 2, ESRD, Ch 9 6

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(a) ASHD

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: ASHD, atherosclerotic heart disease.

Vol 2, ESRD, Ch 9 7

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(b) AMI

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: AMI, acute myocardial infarction.

Vol 2, ESRD, Ch 9 8

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(c) CHF

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: CHF, congestive heart failure.

Vol 2, ESRD, Ch 9 9

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(d) CVA / TIA

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviations: CVA/TIA, cerebrovascular accident/transient ischemic attack.

Vol 2, ESRD, Ch 9 10

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(e) PAD

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: PAD, peripheral arterial disease.

Vol 2, ESRD, Ch 9 11

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(f) AFIB

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: AFIB, atrial fibrillation.

Vol 2, ESRD, Ch 9 12

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(g) SCA / VA

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviations: SCA/VA, sudden cardiac arrest and ventricular arrhythmias.

Vol 2, ESRD, Ch 9 13

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(h) PCI

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: PCI, percutaneous coronary interventions.

Vol 2, ESRD, Ch 9 14

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(i) CABG

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: CABG, coronary artery bypass grafting.

Vol 2, ESRD, Ch 9 15

Figure 9.4 Probability of survival of ESRD patients with or without a cardiovascular disease or undergoing a cardiovascular procedure, 2011-2013

(j) ICD / CRT / D

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis, peritoneal dialysis, and transplant patients with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from July, 1, 2010 to December 31, 2010, and whose first ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2011. Abbreviation: ICD/CRT/D, implantable cardioverter defibrillators/cardiac resynchronization therapy with defibrillator devices.

Vol 2, ESRD, Ch 9 16

Table 9.2 Characteristics of patients with heart failure, by treatment modality, 2013

Age

0-21

22-44

45-64

65-74

75+

Sex

Male

Female

Race

White

Black/African

American

Other

Diabetes

No

Yes

Systolic +/- Diastolic heart failure

HD PD

N

8,431

5,714

7,708

5,756

681

4,029

10,116

%

7

887

5,047

4,034

4,170

0.0

6.3

35.7

28.5

29.5

59.6

40.4

54.5

40.7

4.8

28.5

71.5

N

1

100

303

241

164

476

333

555

216

38

%

0.1

12.4

37.5

29.8

20.3

58.8

41.2

68.6

26.7

4.7

323

486

39.9

60.1

Diastolic only heart failure

HD PD

N

1

774

4,413

3,565

3,811

0.0

6.2

35.1

28.4

30.3

5,484

7,080

6,547

5,386

631

3,505

9,059

%

43.6

56.4

52.1

42.9

5.0

27.9

72.1

N

0

63

231

142

125

264

297

344

187

30

203

358

%

0.0

11.2

41.2

25.3

22.3

47.1

52.9

61.3

5.3

36.2

63.8

Heart failure, unspecified

HD PD

N % N %

11

1,852

9,295

6,643

6,858

0.0

7.5

37.7

26.9

27.8

6 0.5

156 13.2

474 40.1

307 26.0

238 20.2

12,573

12,086

12,720

33.3

10,683

1,256

7,095

17,564

51.0

49.0

51.6

43.3

5.1

28.8

71.2

611 51.7

570 48.3

755 63.9

344 29.1

82 6.9

439 37.2

742 62.8

Data Source: Special analyses, USRDS ESRD Database. Point prevalent hemodialysis and peritoneal dialysis patients at all ages, with Medicare as primary payer on January 1, 2011, who are continuously enrolled in Medicare Parts A and B from

July, 1, 2010 to December 31, 2010, ESRD service date is at least 90 days prior to January 1, 2011, and survived past 2012.

Abbreviations: HD, hemodialysis; PD, peritoneal dialysis.

Vol 2, ESRD, Ch 9 17

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