Wayland Baptist University _______ Campus School of Mathematics and Sciences WAYLAND MISSION STATEMENT: Wayland Baptist University exists to educate students in an academically challenging, learning-focused and distinctively Christian environment for professional success and service to God and humankind. COURSE NO. AND TITLE: CHEM 4403-section; Biochemistry II TERM: NAME OF INSTRUCTOR: OFFICE PHONE NO. AND WBU EMAIL ADDRESS: OFFICE HOURS, BUILDING, AND LOCATION: Students are encouraged to call or stop by the office any time the instructor is available, including nonposted office hours. CLASS MEETING TIME AND LOCATION: CATALOG DESCRIPTION: Continuation of CHEM 4402; emphasis is placed on enzyme kinetics, metabolic pathways and biosynthesis. Lecture three hours, laboratory three hours. $45 fee. PREREQUISITES: CHEM 3404 – Organic Chemistry II REQUIRED RESOURCES: Thomas M. Devlin, Textbook of Biochemistry with Clinical Correlations, 7th ed. (2006) Wiley-Liss, Hoboken, NJ. *or choose from the official booklist COURSE OUTCOME COMPETENCIES: 1. At the conclusion of the course, the student should be able to describe and explain the fundamental principles of: a. Enzyme classifications, kinetics and control mechanisms. b. Membranes and membrane transport proteins. c. Metabolism. d. Carbohydrate metabolism. e. Bioenergetics and oxidative metabolism. f. Photosynthesis. g. Lipid metabolism. h. Metabolic interrelationships. i. Hormone biochemistry. 2. The laboratory will provide an opportunity for hand-on exercises and laboratory experiments which will illustrate biochemical concepts emphasized in lecture. The student will be able to carry out controlled experiments, collect and evaluate data, perform basic statistical analysis and develop scientific writing ability. Competency will be assessed using written laboratory reports and graded lab exercises. 3. The student will read and evaluate the experimental design and collected data of experiments reported in articles selected from the primary scientific literature. Competency will be measured by written evaluation of the selected articles. ATTENDANCE REQUIREMENTS: “The University expects students to make class attendance a priority.” 1. Participation in University sponsored events is an excused absence. Other absences MAY be excused at the discretion of the instructor. 1 2. ALL absences (including for University sponsored events) must be discussed with the instructor BEFORE the absence or they will be unexcused. 3. If an exam or laboratory work is missed due to an excused absence, it must be made-up within a week of the scheduled date. Unexcused absences from exams or laboratory can NOT be madeup and a grade of 0% will be recorded for that exam. 4. Lab write-ups are considered to be a part of the scheduled lab time and are due before the next assigned laboratory exercise is begun. 5. If a student misses 25% of lecture classes or laboratories the student may be dropped from the class. STATEMENT ON PLAGIARISM AND ACADEMIC DISHONESTY: Wayland Baptist University observes a zero tolerance policy regarding academic dishonesty. Per university policy as described in the academic catalog, all cases of academic dishonesty will be reported and second offenses will result in suspension from the university. DISABILITY STATEMENT: In compliance with the Americans with Disabilities Act of 1990 (ADA), it is the policy of Wayland Baptist University that no otherwise qualified person with a disability be excluded from participation in, be denied the benefits of, or be subject to discrimination under any educational program or activity in the university. The Coordinator of Counseling Services serves as the coordinator of students with a disability and should be contacted concerning accommodation requests at (806) 291-3765. Documentation of a disability must accompany any request for accommodations. It is the responsibility of the student to inform the instructor of any disability that may require accommodation during the lecture or laboratory portions of the course. It is of particular importance to report any condition or disability that may affect the laboratory safety of the individual or others. Information provided for this purpose will be kept strictly confidential and will not in any way affect the individual’s course grade. COURSE REQUIREMENTS AND GRADING CRITERIA: 1. Four hour exams (64%). Hour exams will cover assigned reading and homework problems. 2. Comprehensive final exam (16%). 3. Laboratory (20%). Laboratory work will consist of laboratory exercises, experiments, a biochemical literature assignment, and laboratory reports. Unless otherwise announced, completed laboratory reports will generally be due at the beginning of the next regularly scheduled lab period. 4. Homework. Homework problems will be assigned for each topic covered. Reading the textbook and completion of homework assignments will be required for success on the exams. Homework problems will not be collected or graded. Answers to the assigned homework problems will be posted on the course Blackboard site. 5. Abiding by laboratory safety guidelines at all times. Failure to do so may result in dismissal from the lab and subsequent reduction in course grade. 6. All assignments turned in late will be penalized at a rate of 20% per school day. Hour Exams (HE) (4 @ 16% each) Laboratory (LB) Final Exam (FE) Final Grade = COURSE EVALUATION: A 90-100% B 80-89% C 70-79% 2 D F W I 60-69% 0-60% Withdrawal Incomplete* *An incomplete may be given within the last two weeks of the semester to a student who is passing but has not completed required work for reasons beyond the student’s control. The incomplete will be removed only if the required work is completed by the date during the next academic term given in the academic catalogue. Failure to complete the work by this date will result in the grade of F. Students shall have protection through orderly procedures against prejudices or capricious academic evaluation. A student who believes that he or she has not been held to realistic academic standards, just evaluation procedures, or appropriate grading, may appeal the final grade given in the course by using the student grade appeal process described in the Academic Catalog. Appeals may not be made for advanced placement examinations or course bypass examinations. Appeals are limited to the final course grade, which may be upheld, raised, or lowered at any stage of the appeal process. Any recommendation to lower a course grade must be submitted through the Executive Vice President/Provost to the Faculty Assembly Grade Appeals Committee for review and approval. The Faculty Assembly Grade Appeals Committee may instruct that the course grade be upheld, raised, or lowered to a more proper evaluation. TENTATIVE COURSE OUTLINE: CHAPTER MAJOR TOPICS 10 Enzymes: Classification, Kinetics and Control 12 Biological Membranes: Structure and Membrane Transport MAJOR TEST #1 15 Carbohydrate Metabolism I: Major Metabolic Pathways and Their Controls 14 Bioenergetics and Oxidative Metabolism handouts Photosynthesis MAJOR TEST #2 16 Carbohydrate Metabolism II: Special Pathways and Glycoconjugates 17 Lipid Metabolism I: Synthesis, Storage and Utilization 18 Lipid Metabolism II: Special Lipids MAJOR TEST #3 22 Metabolic Interrelationships 23 Biochemistry of Hormones MAJOR TEST #4 FINAL EXAM ADDITIONAL INFORMATION: optional ACADEMIC HONESTY: “University students are required to conduct themselves according to the highest standards of academic honesty.” Any student guilty of cheating or other forms of academic dishonesty may be penalized at the instructor’s discretion by one or more of the following: 1. Assigning a grade of F (0%) to the work in question. 3 2. Assigning a grade of F for the entire course. 3. Recommendation for more severe punishment; including probation, suspension, or expulsion from the University (see student handbook for further information). Revised 03/18/15 4