Grants Overview
Research Resources
Catrina Codd BSc, MPH
Research Manager
Research-driven innovation
Queensland Emergency Medicine Research Foundation
Funding
• Trainees – up to $20,000
• Staff Specialists – up to $50,000
• Project Grants - Funding of up to $100,000 per year for
up to 3 years.
• Program Grants - Funding up to $250,000/ year for up
to 3 years.
• Leverage Funding of up to $50,000 per annum for up to
3 yrs
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Queensland Emergency Medicine Research Foundation
Research Fellowship Scheme
• Research Fellowship Scheme - contribute to the salary
costs
– Short Research Fellowship (Full-time or Part-time)
This is a 6 - 12 month full-time (or 12-24 month parttime) Maximum of AUS $150,000 per annum.
– Research Fellowship (Full-time or Part-time)
(research based Masters, Professional Doctorate,
PhD, DrPH or MD). Maximum of AUS $150,000 per
annum up to 3 years.
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Thinking
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“In order for competent and innovative knowledge exploration to take place
in parallel with conventional data gathering, it is important that creative and
skilled reflection will count as original research in medical academe.
Competent analytical thinking should be considered just as important and
valuable to medicine as competent doing of traditional, empirical research.”
Getz L, Luise Kirkengen A, Hetlevik I. Too much doing and too little thinking in
medical science! Scand J Prim Health Care. 2008;26(2):65-6. Free article at journal
site – This article includes a quote from the 1915 Nobel laureate in physics William
Bragg. In the middle of one of physics’ major paradigm shifts he is supposed to have
said:
The important thing in science is not so much to obtain
new facts as to discover new ways of thinking about
them.
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Ask “why?” Ask “what if?”
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Work on Important Problems
• Ten simple rules for doing your best research, according
to Hamming. Erren TC, Cullen P, Erren M, Bourne PE.
PLoS Comput Biol. 2007 Oct;3(10):1839-40. Free article
in PMC | at journal
Presentation title, Event name, Event date (edit by going to View>Header and Footer)
Queensland Emergency Medicine Research Foundation
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Logistics
• Taylor DM, Practical Issues in the design and execution
of an emergency medicine research study. Emergency
Medicine (1999) Vol 11 Issue 3, 167-174
• Mentors – Published in your area?
• Mentors – both Emergency Medicine Research and
Therapeutic Area Specialist
• Mentors – ACEM Researcher Database available via
ACEM Members section www.acem.org.au
>Members>Clinical Trials Group>Researchers
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Office of Health and Medical
Research – Qld Health
• Ethics Review & Governance
• National Statement on Ethical Conduct in Human
Research
• Australian Code for the Responsible Conduct of
Research
• Fellowships & Grants for Investing in People & Projects
• Intellectual property
• Commercialisation
http://www.health.qld.gov.au/ohmr/html/researchers.asp
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Mater Health Services
• http://www.mater.org.au/Home/Research/HumanResearch-Ethics-Committee.aspx
• Mater Medical Research Institute http://www.mmri.mater.org.au/
• http://www.materfoundation.com.au
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University Research Divisions
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Griffith University - http://www.griffith.edu.au/research
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James Cook University - http://www.jcu.edu.au/div2/research.shtml
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Writing Grants - http://www.research.qut.edu.au/development/develop/writingstrategies.jsp
Mentoring - http://www.research.qut.edu.au/development/develop/mentoring/
UQ - http://www.uq.edu.au/research/rrtd/grants-unit
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Research Services: http://cms.jcu.edu.au/researchservices/index.htm
Assistance for grant applicants:
http://cms.jcu.edu.au/researchservices/grants/assistance/index.htm
Checklist for a winning Grant:
http://cms.jcu.edu.au/researchservices/grants/assistance/JCUPRD_038852
QUT - http://www.research.qut.edu.au/
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Research support: http://www.griffith.edu.au/research/research-support
Burns, Trauma & Critical Care Research Centre
http://www.som.uq.edu.au/research/burns/default.asp
Bond University - http://www.bond.edu.au/research/
Presentation title, Event name, Event date (edit by going to View>Header and Footer)
Queensland Emergency Medicine Research Foundation
Research-driven innovation
Logistics
NATIONAL ADVICE SERVICE FOR
RESEARCHERS http://www.rddirect.org.uk/
comprehensive research site. Research
Process Flowchart
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Resources
Lessons from a Novice EMS Researcher
Henry E. Wang, M.D., M.P.H.
Assistant Professor, Department of Emergency Medicine
University of Pittsburgh School of Medicine
http://www.saem.org/saemdnn/ResearchResources/tabid/3
59/Default.aspx
Grantsmanship in Academic Emergency Medicine
Kelly D. Young, MD, Harbor-UCLA Medical Center
Roger J. Lewis, MD, PhD, Harbor-UCLA Medical Center
http://www.saem.org/publicat/chap11.html
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Queensland Injury Surveillance Unit
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QISU has been analysing injury surveillance data collected by Queensland Emergency Departments
since 1988. Currently 17 Queensland emergency departments participate in QISU data collection. This
data allows us to develop injury profiles based on age, sex, injury mechanism, injury type, location,
occupation, time of presentation, intent etc.
QISU are happy to assist with any requests for data or support. QISU data could be useful in terms of:
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Describing the burden of injury in a local community or demographic group
Describing the burden of injury care on a local emergency department
Describing specific injuries that are relevant to your department (e.g. ATV injuries, MBA, drowning)
Analysing mechanism of injury to inform prevention strategies for specific injuries (e.g. falls, MVA, assault)
Putting your injury profile in a broader Queensland context
QISU can also assist with injury prevention networks, academic contacts and research strategies in
the area of injury mechanism and prevention.
Even if your department does not collect data, we may be able to provide relevant statistics or support
for your research proposal.
If you are interested in starting a new collection site, we are able to offer advice, training and
assistance. We recognise that data collection requires commitment and effort on the part of triage
nurses in increasingly busy emergency departments. Thanks to those who have contributed to this
resource over the years.
Contact Dr Ruth Barker, Emergency Paediatrician, Mater Children’s Hospital, Acting Director, Queensland Injury
Surveillance Unit, Queensland Safe Communities Support Centre, E: ruthb@qisu.org.au W: www.qisu.org.au
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Research Technical Guide
Developing the Methodology
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Defining and refining your research question
Searching the literature
Project management and time management
Writing a research proposal
Sample size calculation
Sources of funding
Ethics, information and consent
Carrying out a pilot study
Bias and confounding
Validity and generalisability
Pragmatic versus explanatory trials
http://www.collemergencymed.ac.uk/CEM/Research/Technical%20Guide/default.asp
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Specific Methodologies
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Evaluating a therapy
Evaluating a diagnostic test
Predicting an outcome
Measuring health
Surveying opinions, attitudes and beliefs
Systematic reviews
Measuring cost-effectiveness
Qualitative research
College guidance on creating surveys
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Writing Research Proposal
• http://www.collemergencymed.ac.uk/CEM/Research/Writ
ing%20A%20Research%20Proposal/default.asp
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Clinical Research Training On-Line
• http://www.cc.nih.gov/training/training/crt.html
• Web-based Clinical Research Training On-Line Course
for Principal Investigators addresses one of the essential
standards (training and education) approved by the
National Institutes of Health (NIH) for performing clinical
research in the Intramural Research Program. All NIH
intramural clinical principal investigators are required to
take the course and successfully complete a final exam.
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How to win that grant
• With examples
• www.med.emory.edu/postdoc/docs/PrivateFundingWOR
KSHOP-OPE1%2008a.ppt Janet Gross “Seeking and
Obtaining Private Funding for Research” This is a great
powerpoint presentation for obtaining funding – see
slides 5 and 6 and 69
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The QEMRF Process
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Registration – basic information required
Eligibility – who can be a Principal Investigator
Co-investigators – building your research team and academic links
Asking the right question with a focus on Emergency Medicine
Conducting your literature review
Components of a full project title, short title and lay title.
Lay description – keeping it to 300 words and how to make it lay
Preparing a solid background
Clear aims, research question and hypotheses
Significance of the project
Milestones
Ethical and other approvals
Research plan
Capacity and infrastructure
Budget – what’s allowed and what’s not, how to justify your budget
The Administrating institution
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Registration - http://portal.qemrf.org.au/default.aspx
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Registration – minimal info needed
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Short Title
Long Title
Principal Investigator – contact details
Budget
Trainee details
Submitted by
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Queensland Emergency Medicine Research Foundation
Eligibility
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FACEM
FRACP PEM
Public Hospital
Queensland
Emergency Medicine
Co-Investigators can be anyone
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Co-investigators
• Collaborate from the start
• Find someone who is successful at getting grants,
review one of their best and work together on yours
• Track record
– Funding
– Publications
– Impact of the research
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Collaborate – before the grant is
written
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Applied Mathematicians
Epidemiologists and Statisticians
Scientists
Health Economists
Nursing and Allied Health
Emergency Services: Fire, Ambulance, Police
Professionals (Legal, Psychology, Industrial Design,
Engineering etc)
• Community and Industry
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The right question
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Does it really bug you at work?
Are you passionate about it?
Refine it into a doable project
Google
• Hayes RB. Forming research questions. Journal of Clinical
Epidemiology 2006; 59:881-886.
• Tugwell P, McGowan J. Finding information about the burden of
disease. Journal of Clinical Epidemiology 2006; 59:887-892.
• Haynes RB, Sackett DL, Guyatt GH, Tugwell P. Clinical
epidemiology: how to do clinical practice research 3rd Edition.
Lippincott Williams and Wilkins, Philadelphia, 2006.
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The right question (Guyatt 2006)
You should consider:
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is there sufficient doubt?
what is the burden of illness?
do others think that there is a problem?
what is the potential economic impact of resolving the
question?
• if the question has not been definitively answered, is it
the next logical step?
Guyatt G. Preparing a research protocol to improve
chances for success. Journal of Clinical Epidemiology
2006; 59:893-899.
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Literature review
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Search WHO International Clinical Trials Registry Platform
(ICTRP) http://apps.who.int/trialsearch/ to ensure there are
no similar trials are currently underway and not yet published
Make friends with a good librarian
Reference the Cochrane Library – even if no reviews have
been done, note that you have looked.
http://www.cochrane.org/
ACEM resources www.acem.org.au Members section>Clinical Trials
Group>Evidence Based Medicine Resources – Tips for beginning researchers
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Health Information Research Unit (Evidence-Based Health
Informatics) at McMaster University website:
http://hiru.mcmaster.ca/hiru/HIRU_Hedges_home.aspx
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Titles: Short and Full
• Full title – include the study design, eg randomised,
cohort, case-control, prospective etc See Research
Proposal http://www.petech.ac.za/robert/resprop.htm :
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the WHO or/and WHAT is researched;
the WHERE;
the WHEN;
the HOW;
and an indication of the ENVISAGED SOLUTION or possible
NEW PRODUCT.
• For an abbreviated view see: O'Brien K and Wright J (2002),
How to write a protocol, Journal of Orthodontics, Vol. 29, No. 1, 5861. http://jorthod.maneyjournals.org/cgi/content/full/29/1/58 - full text
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Lay description
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Media releases
Used in QEMRF profile and reports
No more than 300 words
Give it to a lay person to read
Consumer Medical Information Vocabulary
http://www.medicinesaustralia.com.au/pages/images/Vo
cabulary%20for%20CMI%20%20An%20Explanatory%20Note.pdf, to explain medical
terms
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Background
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Have you or your team done any work in this area before
Is this research building on your work?
Burden of disease
National Institute of Allergy and Infectious Diseases
(NIH) template with examples
http://www3.niaid.nih.gov/research/resources/toolkit/prot
ocol/
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Aims, research question and
hypotheses
• Resources for Behavioral Science Researchers http://www.theresearchassistant.com/tutorial/2-1.asp - The
Relationship Between the Research Question, Hypotheses, Specific
Aims, and Long-Term Goals of the Project
• The research question should contain the basic elements of the
(PICOT) – participants, intervention, comparison group and
outcomes and time
• Aims – should include action verbs – “to determine, to identify, to
verify, to describe, to calculate” - Ref: Ahmed AM, Hints to Prepare a
Research Proposal, Education, Nov 2006http://www.sghgroup.com/sghmj/Articles/Hints_for_research_propos
al.pdf
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http://www.ferne.org/Lectures/2008_research_lecture/ppspdf/ferne_2008_research_l
ecture_sloan_research_hypothesis_092508_final_gray.pdf
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Hypotheses
• Good and bad examples of hypotheses: Conducting
Successful EM Resident Research: Generating
Research Ideas and Hypotheses – Powerpoint slides by
Edward P. Sloan, MD, MPH, FACEP,
• Eg: Cost: Abdominal Stab Wound Management
– Bad: Observation is cheaper than laparotomy
– Good: Patients observed have a similar outcome with
a 50% reduction in medical costs.
http://www.ferne.org/Lectures/2008_research_lecture/
ppspdf/ferne_2008_research_lecture_sloan_research
_hypothesis_092508_final_gray.pdf
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The rest
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Significance of the project
Milestones
Ethical and other approvals
Research plan
Capacity and infrastructure
Budget – what’s allowed and what’s not, how to justify
your budget
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Significance of the project
• Why is the question worth studying?
• Why is it important to Emergency Medicine?
• What is the boarder significance – ie to other disciplines
and to the broader community?
• Identifying how the research will align with the goals of
QEMRF to advance emergency medicine in
Queensland. The purpose of the Foundation is to
support high quality research directed at improving the
care of patients in Emergency Departments and to
develop Emergency Medicine research capacity in
Queensland.
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Milestones
• Estimate the time it will take for each step – break each
down to the smallest point.
• Double it
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Ethics
• Queensland Health
http://www.health.qld.gov.au/ohmr/html/regu/regu_home.
asp
• Mater Health Services:
http://www.mater.org.au/Home/Research/HumanResearch-Ethics-Committee.aspx
• University research departments
http://www.qemrf.org.au/page9/page9.html
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Research Plan
• Step-by-step guide to setting up a clinical trial – The
Royal Children’s Hospital Melbourne – Clinical
Epidemiology and Biostatistics Unit (CEBU)
http://www.rch.org.au/cebu/clinicaltrials.cfm?doc_id=940
1
• Good examples of wording and how to write - How to
write a protocol Kevin O'Brien and Jean Wright, Journal
of Orthodontics, Vol. 29, No. 1, 58-61, March 2002
http://jorthod.maneyjournals.org/cgi/content/full/29/1/58 free full text.
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Schematic of Study Design
• Rosenberg, John P. and Yates, Patsy M. (2007-11)
Schematic representation of case study research
designs. Journal of Advanced Nursing, 60 4: 447-452.
• A simple example of a schematic can be found in Lang,
Tom (2006) Documenting Research in Scientific Articles:
Guidelines for Authors: Reporting Research Designs and
Activities. Chest, 130;1263-1268.
http://www.chestjournal.org/content/130/4/1263.full.pdf
• Use word – tables or drawing, PowerPoint, Visio or Mac
products.
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Capacity and Infrastructure
• Demonstrate the capacity to complete the research
within time and funding constraints.
• Document here if the team have worked together
successfully previously. Cover all components required
to complete the research and write it up.
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Resources
• Emergency Medicine Journal 2002;19:242-246;
doi:10.1136/emj.19.3.242 © 2002 BMJ Publishing Group Ltd and
the College of Emergency Medicine. RESEARCH SERIES
• Clinical research in emergency medicine: putting it together A
M T Good1 and P Driscoll2 1 Accident and Emergency Department,
Royal Liverpool University Hospital, Liverpool, UK2 Accident and
Emergency Department, Hope Hospital, Salford, UK ABSTRACT
The difficulties in conducting good clinical research in emergency
medicine can be overcome. This article will begin by identifying the
main difficulties faced by the emergency medicine researcher. It will
then discuss some solutions through the development and
application of the research protocol. Finally, recommendations will
be made with regard to writing for publication.
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Networking
• Wright, D, Crouch, R, Clancy, M (2005). Role of
networks in supporting emergency medicine research:
findings from the Wessex emergency care research
network (WECReN). Emerg. Med. J. 22: 80-83 [Full
Text]
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Clinical Trials – Searching Registries
• INTERNATIONAL CLINICAL TRIALS REGISTRY
PLATFORM SEARCH PORTAL
http://apps.who.int/trialsearch/ The Clinical Trials
Search Portal provides access to a central database
containing the trial registration data sets provided by the
registries listed below. It also provides links to the full
original records.
– Every week: Australian New Zealand Clinical Trials Registry, ClinicalTrials.gov,
ISRCTN
– Every 4 weeks: Chinese Clinical Trial Register, Clinical Trials Registry - India,
German Clinical Trials Register, Iranian Registry of Clinical Trials, Sri Lanka
Clinical Trials Registry, The Netherlands National Trial Register
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Clinical Trials
• Register your Clinical Trial: http://www.anzctr.org.au/
• QEMRF GCP Protocol Template:
http://portal.qemrf.org.au/Forms%20and%20Guidlines/Q
EMRF%20GCP%20Protocol%20Template%20V1%2016
%20Sep%202008.doc
• Queensland Clinical Trials Centre:
http://www.uq.edu.au/qctc/
• Queensland Clinical Trials Network:
http://www.qctn.com.au/
• Protocol Workbook - Wombat Collaboration:
http://www.wombatcollaboration.net/doc/WOMBAT_Protocol_Workbook.pdf
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Clinical Trials
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ACEM website>Members>Clinical Trials Group>EMCTG Trial Submission –
Peer review and endorsement process
Predict – Paediatric Research in Emergency Departments International
Collaborative
http://www.pems.org.au/ModCoreFrontEnd/template.asp?PageID=134
Australian Clinical Trial Handbook (A simple, practical guide to the conduct
of clinical trials to International standards of Good Clinical Practice (GCP) in
the Australian context http://www.tga.gov.au/ct/cthandbook.pdf
Trial Protocol Tool – help with writing trial protocols:
http://homepage.mac.com/streweek/Trial_Protocol_Tool/FileSharing31.html
The Trial Protocol Tool: the PRACTIHC software tool that supported the
writing of protocols for pragmatic randomized controlled trials
Journal of Clinical Epidemiology, Volume 59, Issue 11, Pages 1127-1133
S. Treweek, K. McCormack, E. Abalos, M. Campbell, C. Ramsay, M.
Zwarenstein
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Data Management
• "Clinical Data Acquisition Standards Harmonization"
document from the "Clinical Data Interchange Standards
Consortium" http://www.cdisc.org/
• Draft guidelines for Quality Registries. The parent site
http://www.safetyandquality.gov.au/internet/safety/publis
hing.nsf/Content/PriorityProgram-08
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Budget – what’s allowed and what’s
not, how to justify your budget
Allowed:
• Salary for Research Assistants, Officers, Statisticians etc
• Consumables
• Travel for the purposes of research
Not allowed:
• Principal Investigator salary – funding via fellowships
may be possible if linked to a post graduate qualification
• Computer hardware or software – funding should be
sought from other sources for these
• Conference attendance
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The Administrating Institution
• Hospital
– Need to find out who should sign this off –
usually the CEO or COO after legal review
either by hospital lawyer or Research Office
• University
– Research Office
– Sign off may take several weeks
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Publication
• EFFECTIVE MEDICAL WRITING Michelle Biros, MS,
MD, Editor-in –Chief, Academic Emergency Medicine
www.saem.org/meetings/05hand/biros.doc
• EQUATOR Network – Enhancing the QUAlity and
Transparency Of health Research http://www.equatornetwork.org/.
• EQUATOR Network resources enable:
– Better reporting
– Better reviewing
– Better editing
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At any stage feel free to contact:
Catrina Codd BSc, MPH
Research Manager
Queensland Emergency Medicine Research Foundation
c/o Australian Medical Association Queensland
88 L’Estrange Tce, Kelvin Grove Qld 4059
PO Box 123, Red Hill Qld 4059
T +61 7 3872 2256 | F +61 7 3856 4727
E catrina.codd@qemrf.org.au | W www.wemrf.org.au
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