The Pain Market:
Spain Core Therapeutic Report
National Health and Wellness Survey 2010
Method and Sample
 Data Collection
+ Survey administered via the Internet since 2002
+ Data collected during March-May 2010
+ Countries: Spain
 Sample
+ Adults 18+ years of age
+ Sample drawn from the Internet panel maintained by Lightspeed Research
+ Invitations to participate sent to a sample stratified according to:
– Gender
– Age
 Results are projected to reflect the total population using
known population incidences for key subgroups
+ Weighting Variables: Gender and age
+ From the International Data Base of the U.S. Census Bureau and
Organization for Economic Cooperation and Development
2
Spain Sample Size

Key segments of the Pain market are represented by the following sample sizes:
Sample
(n)
Total Spain Adults
Spain Population
Projected Number of
Spain Adults
5,039
35.4 M
868
6.1 M
Severe
100
714 K
Moderate
554
3.9 M
Mild
214
1.5 M
81
572 K
10††
73 K
9††
68 K
357
2.6 M
106
710 K
91
622 K
Rx
77
551 K
OTC‡ Only
81
549 K
Untreated
56
374 K
Experiencing Pain (in the past month)*
Severe:
Rx
OTC‡
Only
Untreated
Moderate:
Rx
OTC‡
Only
Untreated
Mild:
††Caution:
extremely small base size
Products
*Excludes dental problems, headache, menstrual pain or migraine only.
‡OTC/Herbal
3
Spain Pain Prevalence 2010
Use Rx
572 K 80%
(n=81)
Total Spain
Adults Population
35.4 M
(n=5,039)
SEVERE
714 K (12%)
(n=100)
OTC‡ Only
73 K 10%
(n=10††)
Untreated
68 K 10%
(n=9††)
Use Rx
2.6 M 66%
(n=357)
Experiencing Pain
(in the past month)*
6.1 M (17%)
(n=868)
MODERATE
3.9 M (64%)
(n=554)
OTC‡ Only
710 K 18%
(n=106)
Untreated
622 K 16%
(n=91)
Use Rx
551 K 37%
(n=77)
MILD
1.5 M (24%)
(n=214)
*Excludes dental problems,
headache, menstrual pain or
migraine only.
OTC‡ Only
549 K 37%
(n=81)
Untreated
374 K 25%
(n=56)
††Base
too small to project to total population (n<15)
Products
Questions reference for this slide include: HH10, HH20, PN5, PN15, PN20, PN95, PN120, DB40 (See Appendix)
‡OTC/Herbal
4
Spain Pain Brand Usage 2010
Total Spain Adults Population
35.4 M (n=5,039)
Experiencing Pain (in the past month)*
6.1 M (17%) (n=868)
Total Use Rx
572 K 80%
(n=81)
MILD
1.5 M (24%)
(n=214)
MODERATE
3.9 M (64%)
(n=554)
SEVERE
714 K (12%)
(n=100)
All OTC‡ Users
191 K (27%)
(n=26†)
Specific Rx Therapies Used
(By Class of Drug)
††
Strong Opioids
Weak Opioids
294 K
51%
NSAIDs
362 K
63%
††
COX-2s
Anticonvulsants
155 K
27%
††
Amitriptyline
††
Analgesics
All Other Pain Medications ††
Top OTC‡ Therapies Used
(Unaided)
††
Ibuprofen Products
Acetaminophen /
††
Paracetamol
††
Aspirin Products
††
Diclofenac
Others
††
(inc. combination OTCs‡)
(n=12†)
(n=39)
(n=52)
(n=7†)
(n=23†)
(n=0†)
(n=14†)
(n=4†)
(n=13†)
(n=2†)
(n=0†)
(n=0†)
(n=10†)
Total Use Rx
2.6 M 66%
(n=357)
Total OTC‡ Users
1.3 M (32%)
(n=180)
Specific Rx Therapies Used
(By Class of Drug)
††
Strong Opioids
Weak Opioids
1.1 M
43%
NSAIDs
1.8 M
71%
COX-2s
126 K
5%
Anticonvulsants
245 K
10%
††
Amitriptyline
Analgesics
351 K
14%
††
All Other Pain Medications
Top OTC‡ Therapies Used
(Unaided)
Ibuprofen Products
824 K
66%
Acetaminophen /
Paracetamol
406 K
32%
Aspirin Products
187 K
15%
††
Diclofenac
Others
(inc. combination OTCs‡)
621 K
50%
(n=3†)
(n=143)
(n=261)
(n=20†)
(n=34)
(n=0†)
(n=55)
(n=13†)
(n=124)
(n=59)
(n=23†)
(n=5†)
(n=93)
Total Use Rx
551 K 37%
(n=77)
Total OTC‡ Users
620 K (42%)
(n=91)
Specific Rx Therapies Used
(By Class of Drug)
††
Strong Opioids
Weak Opioids
126 K
23%
NSAIDs
418 K
76%
††
COX-2s
††
Anticonvulsants
††
Amitriptyline
††
Analgesics
All Other Pain Medications ††
Top OTC‡ Therapies Used
(Unaided)
Ibuprofen Products
392 K
63%
Acetaminophen /
Paracetamol
167 K
27%
Aspirin Products
128 K
21%
††
Diclofenac
Others
(inc. combination OTCs‡)
292 K
47%
*Excludes dental problems, headache, menstrual pain or migraine only.
‡OTC/Herbal Products
†Caution: small base (n<30)
††Base too small to project to total population (n<15)
Questions reference for this slide include: HH10, HH20, PN5, PN15, PN20, PN30, PN95, PN100, PN120 , DB40 (See Appendix)
(n=0†)
(n=18†)
(n=60)
(n=2†)
(n=2†)
(n=0†)
(n=5†)
(n=3†)
(n=59)
(n=26†)
(n=18†)
(n=3†)
(n=44)
5
Pain Prescription Medication Usage
Pain Prescription Medication Usage
(Experiencing Pain and using Rx)*
Experiencing Pain in Past Month*
Total Rx
Users
Strong
Opioids
Weak
Opioids
NSAIDs
3.7 M
(n=515)
125 K
(n=15†)
1.5 M
(n=200)
2.6 M
(n=373)
67.8
81.1
69.9
44.4
26.7
32.6
7.5
-
59.3
79.7
57.1
31.7
40%
32%
40%
55%
31%
39%
-
16
23
16
8
29%
27%
28%
36%
Duration of Rx Usage (mean # of months)
Experiencing Pain (in the past month)*
Severe
Moderate
Mild
% Extremely/Very Satisfied
Experiencing Pain (in the past month)*
Severe
Moderate
Mild
# Days/Mo. Report Taking Rx (mean)
Experiencing Pain (in the past month)*
Severe
Moderate
Mild
% Requested Specific Rx
Experiencing Pain (in the past month)*
Severe
Moderate
Mild
All Other
Pain
Analgesics Medication
COX-2s
AntiConvulsants
Amitriptyline
182 K
(n=29†)
412 K
(n=59)
0K
(n=0††)
488 K
(n=74)
144 K
(n=20†)
68.8
92.3
69.4
46.1
33.2
57.3
26.9
7.1
33.4
40.5
30.2
9.4
-
64.1
55.3
69.5
33.5
65.5
94.5
44.0
93.9
31%
29%
32%
21%
43%
28%
43%
59%
37%
31%
40%
31%
46%
33%
51%
100%
-
45%
28%
47%
84%
52%
79%
23%
100%
21
21
20
-
15
20
14
8
12
18
12
7
13
15
14
8
24
25
24
15
-
16
18
16
14
16
19
20
4
25%
24%
26%
-
26%
30%
22%
45%
28%
26%
27%
35%
14%
17%
10%
44%
11%
16%
9%
-
-
29%
33%
27%
40%
26%
46%
24%
17%
*Excludes dental problems, headache, menstrual pain or migraine only.
Caution: †small base size; ††extremely small base size
*Note: mean satisfaction taken into consideration if multiple pain therapies are used.
PN35: You indicated you use the following prescription medication(s). Did you request this specific brand from your doctor?.
PN40: How many years and/or months have you been using these prescription medication(s)? If you have been using it less than 1 month, please
enter a “0” for ”years” and “1” for “months”.
PN45: How many days did you use these prescription medication(s) in the past month?
PN50: How satisfied are you with these prescription medication(s)?
Based on 7 point scale where 1=Extremely dissatisfied and 7=Extremely satisfied In 2010, a "stacked" method was used for determining overall
medication satisfaction
6
Comparison of SF-12v2 Physical/Mental Health Scores by
Subgroups to Total Population Score
Physical Health Summary
Mental Health Summary
Total Spain Adults
(35.4 M; n=5,039)
Experiencing Pain (in the past month)*
Severe:
Experiencing
Pain (in the
past month)*
(6.1 M; n=868)
Severe (C)
(714 K; n=100)
Moderate (D)
C
C
CD
CD
(3.9 M; n=554)
Mild (E)
(1.5 M; n=214)
Rx (F)
(572 K; n=81)
OTC‡ Only (G)
(73 K; n=10)
Untreated (H)
Moderate:
(68 K; n=9)
Rx (I)
(2.6 M; n=357)
OTC‡ Only (J)
(710 K; n=106)
Untreated
(622 K; n=91)
Rx
I
(K)
I
(L)
Mild:
(551 K; n=77)
OTC‡ Only (M)
(549 K; n=81)
L
Untreated (N)
(374 K; n=56)
Spain Total Population
Score Mean=48.4
Spain Total Population
Score Mean=47.4
‡OTC/Herbal
Caution: extremely small base size
Products
*Excludes dental problems, headache, menstrual pain or migraine only.
General Health - summary scores.
Letters indicate statistically significant difference @ 95% confidence level between subgroups
7
Pain Interfered With Normal Work During The Past 4 Weeks
Pain Interfered With Normal Work During The Past 4 Weeks
Experiencing Pain (in the
past month)*
Total Exp. Pain
Spain (in the past Severe Moderate
Adults month)*
(C)
(D)
35.4 M
6.1 M
714 K
3.9 M
Mild
(E)
1.5 M
Rx
(F)
572 K
Severe
OTC‡
Only
(G)
73 K
(n=10) (n=9)
(n=5,039)
(n=868)
(n=100)
(n=554)
(n=214)
(n=81)
2%
6%
35%DE
2%
0%
34%
23%
48%DE
26%E
4%
52%
13%
31%CE
22%
11%
4%
34%C
58%CD
7%
16%D
Untreated
(H)
68 K
Moderate
OTC‡
UntrRx
Only
eated
(I)
(J)
(K)
2.6 M
710 K
622 K
Rx
(L)
551 K
Mild
OTC‡
Only
(M)
549 K
Untreated
(N)
374 K
(n=357)
(n=106)
(n=91)
(n=77)
(n=81)
(n=56)
53%
3%
2%
-
1%
-
-
34%
26%
32%JK
15%
15%
5%
4%
2%
27%
11%
32%
27%
31%
28%
16%
19%
30%
40%
42%I
57%
61%
56%
3%
16%I
11%I
9%
19%
23%L
General Health
Extremely
Quite a bit
Moderately
A little bit
No at all
8%
17%
32%
42%
27%
36%
8%
-
3%
-
30%
9%
-
10%
-
‡OTC/Herbal
Products Caution: extremely small base size
Zero % implies a very small value less than 0.5%
*Excludes dental problems, headache, menstrual pain or migraine only.
GH25: During the past 4 weeks, how much did pain interfere with your normal work (including both work outside the home and housework)?
(1-5 Scale: 1=Excellent and 5=No at all)
Letters indicate statistically significant difference @ 95% confidence level between subgroups
8
Physical Health Or Emotional Problems Interfered With
Social Activities During The Past 4 Weeks
Physical Health Or Emotional Problems Interfered With
Social Activities During The Past 4 Weeks
Experiencing Pain (in the
past month)*
Total Exp. Pain
Spain (in the past Severe Moderate
Adults month)*
(C)
(D)
35.4 M
6.1 M
714 K
3.9 M
Mild
(E)
1.5 M
Rx
(F)
572 K
Severe
OTC‡
Only
(G)
73 K
(n=10) (n=9)
(n=5,039)
(n=868)
(n=100)
(n=554)
(n=214)
(n=81)
2%
4%
24%DE
2%
1%
27%
8%
13%
29%DE
12%E
7%
30%
27%
Untreated
(H)
68 K
Moderate
OTC‡
UntrRx
Only
eated
(I)
(J)
(K)
2.6 M
710 K
622 K
Rx
(L)
551 K
Mild
OTC‡
Only
(M)
549 K
Untreated
(N)
374 K
(n=357)
(n=106)
(n=91)
(n=77)
(n=81)
(n=56)
11%
3%
-
1%
-
3%
-
18%
14%
8%
10%
10%
5%
7%
28%
34%JK
23%
16%
22%
20%
26%
28%
34%
42%I
42%
38%
25%
20%
35%I
32%I
26%
34%
42%
General Health
All of the time
Most of the time
Some of the time
A little of a time
None of the time
8%
19%
30%
41%
27%
30%
25%
28%
29%
22%
13%
31%C
36%C
7%
24%C
33%CD
26%
14%
3%
38%
17%
9%
42%
‡OTC/Herbal
Caution: extremely small base size
Products
*Excludes dental problems, headache, menstrual pain or migraine only.
GH35: During the past 4 weeks, how much of the time has your physical health or emotional problems interfered with your social activities (like
visiting friends, relatives, etc.)? (1-5 Scale: 1=all of the time and 5=None of the time)
Letters indicate statistically significant difference @ 95% confidence level between subgroups
9
Spain Adult Work Productivity and Activity Impairment
Spain Adult Work Productivity and Activity Impairment
Experiencing Pain (in the
past month)*
Total Exp. Pain
Spain (in the past Severe Moderate
Adults month)*
(C)
(D)
35.4 M
6.1 M
714 K
3.9 M
(n=5,039)
Employed full time
Absenteeism^
% work time missed due
to health – past 7 days
(mean)
Presenteeism^
% impairment while
working due to health
(mean)
Work Productivity
Loss^
% overall work
impairment due to
health (mean)
Activity Impairment
% activity impairment
due to health (mean)
(n=868)
Mild
(E)
1.5 M
Rx
(F)
572 K
Severe
OTC‡
Only
(G)
73 K
(n=81)
(n=10) (n=9)
(n=100)
(n=554)
(n=214)
45%CD
25%
-
Untreated
(H)
68 K
Moderate
OTC‡
UntrRx
Only
eated
(I)
(J)
(K)
2.6 M
710 K
622 K
Rx
(L)
551 K
Mild
OTC‡
Only
(M)
549 K
Untreated
(N)
374 K
(n=357)
(n=106)
(n=91)
(n=77)
(n=81)
(n=56)
-
29%
43%I
37%
41%
50%
44%
37%
34%
20%
33%C
4.6
12.7
41.8DE
12.8
6.3
41.8
-
-
17.7J
2.3
11.2
7.1
5.7
6.1
17.1
25.1
38.3
25.4
22.9
38.3
-
-
28.6
21.1
22.1
25.2
21.4
22.3
20.1
33.6
62.8DE
33.9
26.6
62.8
-
-
40.1J
21.4
30.5
29.6
24.4
26.3
25.6
41.7
74.4DE
41.6E
26.0
79.2
61.5
47.7
47.2JK
27.0
35.2J
30.6N
24.9
20.9
‡OTC/Herbal
Caution: extremely small base size
Products
^Differing base size
*Excludes dental problems, headache, menstrual pain or migraine only.
All the figures are for presently Full Time employees apart from activity impairment
DE30: What is your employment status?
WPPCTWRK: Percentage work time missed due to health.
WPIMPAIR: Percentage impairment while working due to health.
WPWRKIMP: Percentage overall work impairment due to health.
WPACTIMP: Percentage activity impairment due to health.
(0-10 Scale: 0=health problems had no effect on my work and 10=health problems completely prevented me from working)
Letters indicate statistically significant difference @ 95% confidence level between subgroups
10
Type of Pain Conditions
Pain population, prevalence of conditions causing pain by pain severity
(Respondents with pain in the past month)
Experiencing Pain (in the past month)*
Severe (C)
Moderate (D)
Mild (E)
(714 K; n=100)
(3.9 M; n=554)
(1.5 M; n=214)
Back pain
13%
67%
19%
Joint pain
15%
66%
19%
Neck pain
15%
66%
19%
Headache
12%
64%
24%
Arthritis pain
17%
66%
Migraine
28%
Dental pain
15%
Sprains or strains
13%
Shoulder pain/stiffness
16%
Surgery or medical procedure
29%
57%
71%
57%
67%
63%
16%
Experience Pain
(in the past month)*
(6.1 M; n=868)
61%
40%
29%
35%
17%
15%
12%
14%
10%
31%
17%
8%
*Excludes dental problems, headache, menstrual pain or migraine only.
PN15: Please indicate which of the following conditions have caused you to feel pain in the past month.
Letters indicate statistically significant difference @ 95% confidence level between subgroups
10%
23%
7%
11
Experience Symptoms/Side Effects –
Among Rx Opioid Users
Experience Symptoms/Side Effects – Among Rx Opioid Users
(Respondents with pain in the past month (qualified respondents), taking opioid medications, experiencing symptoms)
Experience Pain
(in the past month)*
(239 K; n=37)
Experiencing Pain (in the past month)*
Moderate (D)
Mild (E)
Severe (C)
(77 K; n=12††)
(149 K; n=23†)
(13 K; n=2††)
Nausea
NA
Abdominal pain / discomfort
NA
Dizziness
NA
Constipation
Sleepiness
NA
Trouble thinking clearly
NA
Other digestive symptoms
Vomiting
NA
Feeling moody, irritable,
anxious, or restless
NA
Diarrhea
NA
NA
Bloating
NA
NA
Other
None of above
NA
NA
NA
Caution: †small base size; ††extremely small base size
*Excludes dental problems, headache, menstrual pain or migraine only.
PN60: Please indicate the symptoms you experience while taking <insert name(s) of opioid medication> for your pain?
No statistically significant difference @ 95% confidence level between subgroups
12
Spain NHWS 2010 Data
 When referencing data from this report please use the following
citation:
+ Kantar Health. September 2010. NATIONAL HEALTH AND
WELLNESS SURVEY, 2010 [Spain]. Princeton, NJ.
CONTACT INFORMATION

Global Headquarters
Kantar Health
Health Sciences Practice
1 Independence Way, Suite 220, Princeton, NJ 08540
Telephone: +1 (609) 720 5480 Fax: +1 (609) 720 5481
11 Madison Avenue, 12th Floor, New York, NY 10010
Telephone: +1 (212) 706 4279 Fax: +1 (212) 647 7659
13