Update: Bio-economy Strategy
Presentation to the
Portfolio Committee 27 May 2015
Outline
•The Bio-economy Strategy
Definition; Systems approach; Metrics;
Opportunity; Challenges; & Governance
•Actions and activities:
Agriculture
Health Innovation
Industry & Environment
IKS-based Technology Innovation
Defining the Bio-economy
Refers to activities that make use of bio-innovations,
based on biological sources, materials and processes
to generate sustainable economic social and
environmental development.
In consultation with relevant stakeholders, the DST
“has identified 3 key economic sectors – agriculture,
health and industry – as being the most in need of, and
likely to benefit from key levers to drive the
implementation of the [strategy]”
Agriculture
Health
Industry & Environment
3
So what is new in
the Bio-economy
strategy?
(a) Coordinated, specific
(b) Focused Value Chain
(c) System enablers
Opportunistic
Government Departments
CSIR
Funding
Bodies
NRF
DRDLR
DST
DEA
DoH
DTI
DAFF
MRC
Universities
Provincial
Research
Institutes
ARC
Science
Councils
R,D & I
TIA
ICGEB
IDC -VCs
Bio-economy
Platforms &
service
PPPs eg
Biovac
providers
Private sector
not-for-profit
Aeras, Aurum,
MMV, EDCTP
MBI
Private sector
PUBLIC
Pharmaceutical;
Agricultural; Industrial
SAPPI/Mondi; Winter Cereals
Trust; SMRI; Novartis; Pfizer;
DRI;PATH; L’Oreal; Afriplex;
Nestle
BiosafetySA
Prograrmme
PUB Prog
Gates
Rockerfeller,
Foundations
Small companies,
eg Resyn, Kappa,
Xsit, Inqaba, etc
Communities;
NGO’s; interface with
science and business
5
SYSTEMS APPROACH
•
•
•
Coordination: awareness, national objectives,
teamwork and cooperation/collaboration
Strategic programmes to provide emphasis in
priority areas
System support initiatives (HCD, service platforms,
IP management, entrepreneur training, pilot scale
facilities; Clinical trialing resources, etc)
Coordinating committees
National use of MRC, ARC, CSIR expertise
Techno-feasibility assessments
6
Opportunity of Bio-innovation
√
√
√
√
√
•In 2014 South Africa’s GDP was R3,8 trillion.
•Top 7 DST investee biotech co’s R1 billion turnover.
•Need to benchmark current bio-economy (NACI)
•US & European bio-economies target 5-6% GDP by 2030
.
•If SA to reach that, it would form approx R190 billion (today’s terms)
.
7
Challenges of Bio-innovation
• Most highly regulated scientific field(s) of endeavour.
• Most diversified applications (agric, health,
manufacturing, energy, environment, etc). High level
coordination is required.
• Applications for existing industry AND new industry
• Rapidly developing fields (knowledge, equipment,
applications).
• Some controversy (GE, stem cells & cloning).
• The days of single blockbusters are gone. Need for
sophistication, contextualisation, personalisation and
precision.
8
Measuring the Bio-economy
Currently developing a ‘metrics’ approach:
High Level Impacts:
1)
2)
3)
Sophistication of products
Exports of technology products
Unit value of exports
Outcomes per theme (economic, social, environmental)
•
Eg. Technologies localized; household with food security;
medicines developed; revenues generated
Outputs per theme (meeting objectives of themes)
•
Publications; technologies; patents; companies; products
9
Cross cutting & ongoing
activities of the Department
Cross-cutting initiatives
•Public Understanding of Biotechnology (NRF)
•Biosafety Communication Platform (TIA)
•Bioinformatics and Functional Genomics human capital
development (NRF)
•Bioinformatics Platform (CHPC/CSIR)
•Bio-entrepreneurship training (CSIR/TIA/eGoliBio)
•Bioportal development (consortium)
•Bio-economy Metrics (NACI)
Platforms
•Centre for Proteomic and Genomic Research (TIA)
•H3D Human Drug Discovery & Development (TIA)
•Metabolomics (TIA)
•Bioprocessing (TIA)
•Southern African Human Genome Programme (SHIP)
Overview: Agriculture implementation p
Crop Improvement
New Crops
Commercial
crops
Biocontrol
agents and
biopesticides
Animal improvement
Animal
improvement
Vaccines
and
Diagnostics
Aquaculture
Agroprocessing and Agro-engineering
Natural Resource management
Indigenous African Knowledge based Agriculture
Cross cutting initiatives: Agric biotech skills, academic
research capabilities, Tech. Serv. platforms, Biosafety
capacity, Public awareness, IT & bio entrepreneurship
training, Agro-innovation hubs
Food safety and food nutrition
11
Key Bio-economy activities
of the Department
Agriculture - DST projects:
•Eucalyptus Genome Programme (UP + industry)
•Wheat pre-breeding platform (Grain SA + consortium)
•Feasibility study Agro-innovation hubs (part of agri-parks)
TIA projects (some):
•Cassava commercial trials- Limpopo, Mpumalanga + KZN
•Microwave egg pasteurizer (CSIR, UP, industry)
•Post-harvest biocontrol in table grapes (ARC, CSIR +
industry)
•Indigenous flower bulbs (ARC)
•Sweet stem sorghum as biofuel feedstock (UKZN)
•‘Beochic’ as a growth promoter in poultry (Industry)
•AgraChem – fertilizers & biocontrol (Industry)
Overview: Health
Implementation Plan
New or improved
therapeutics &
drug delivery
New vaccines and
other biologicals
New or improved
diagnostics
New medical
devices
Translational Architecture
(ICTs, Knowledge Management, Modelling, Advanced Statistical Analysis)
Development
Discovery
Market
access /
Impact
monitoring
Capacities
&
capabilities
Product development
cycle
Technology
development
Dissemination
Decision
support
Technology
&
knowledge
transfer
Build the Health Innovation System
13
Key Bio-economy activities
of the Department
Health – SHIP projects:
Vaccine &
Biologicals
Therapeutics/
drug delivery
Diagnostics/
devices
HIV
8
3
2
TB
8
3
5
Malaria
-
2
1
NCD
-
7
8
Overview: industry & Environment
Implementation Plan
National Enabling RD&I Platforms
Priority Areas
Biochemicals &
Biologics
Biomaterials
Bioenergy
Biomining,
Waste &
Wastewater
Biomanufacturing
Bioprocessing
Biopharming
Biocatalysis
Biocomposites
BioGROW
BioPAC
Bioresins
Biorefineries
Physical
Chemical
Thermal
Biological
Biomining, Waste
& Wastewater
Beneficiation
Commodity
chemicals
Fine
Chemicals
Pharmaceuticals
Vaccines
Biologics
Enzymes
Biocomposite
Bioplastics
Biosynthetic
materials
Heat
Electricity
Biodiesel
Bioethanol
Remediation
technology
Mineral, oil,
and salt
recovery
Sanitation
solutions
BioMining
Water Biorefineries
15
Key Bio-economy activities
of the Department
Industry & Environment:
DST projects
•Biocatalysis – developing human capital in useful
enzymes (consortium)
• Biorefinery modelling and new product development
•Water Foot-printing Analysis for SA pulp Mills
•From sucrose to high value commodity chemicals
• Energy use reduction and monitoring opportunities in sugar
factories.
•Biomanufacturing Industry Development Centre (CSIR) –
supporting industry start-ups.
•Pyrolysis of plastic/fibre wastes
TIA
•Sweet stem sorghum as biofuel feedstock (UKZN)
•Continuous seed preparation for sugar processing (SMRI,
Tongaat Hullet)
Indigenous Knowledge-based Technology
Innovation
Objective: Mainstreaming IK-based products
Institutional
Technical
>80 community
members trained
Various communities
& knowledge holders
involved/participating
in validation and
prototype
development.
Inclusive
Innovation
Local
Holistic
Research
and
Discovery
Technology
Transfer and
Production
Ubuntu
Model
(Integral)
Humane
Business
Models
and
Marketing
IK-Based
Concept
Generation
Ubuntu
Commerce
and Benefit
Sharing
Economic
Social/Cultural
17
Key Bio-economy activities
of the Department
Indigenous Knowledge-based Technology Innovation
Platform
No. of
Projects
Value-Added Products
African Medicines
Platform
IK-Based
Cosmeceuticals
IK-Based
Nutraceuticals
IK-Based Health
Beverages
IK-Based Tech
Transfer
IK-Based
Commercialisation
3 HIV/AIDS; 1 TB; 1 Diabetes; 1
6 Projects Malaria
8 Projects Skin, hair, ageing
Nutrition, supplements, food
5 Projects products
Moringa, Honeybush, Haw-Haw,
6 Projects Amaranthus, etc
5 Projects
Moringa, Honeybush, Nutri-veg
4 projects drink
Key Bio-economy activities
of the Department
Capacity building: IKS PhD, MSc and undergraduate students
Key Bio-economy activities
of the Department
Partnership with University of Limpopo sitting on Limpopo Agro-food Technology Station (LATS)
Key Bio-economy activities
of the Department
Construction of the Tooseng Processing Facility 15/04/2015
Key Bio-economy activities
of the Department
Some of the Moringa related products that have been developed
Way forward:
Bio-economy 2015/6
Implementation plans
•Finalization & publication
•Presentation to Treasury
Activities
•Creation of Coordinating Committees (including govt,
science councils, industry, academia) to advise DST on
priorities & actions.
•Development of R&D support models (similar to SHIP) at
the ARC and CSIR.
•Techno-feasibility study on Agro-innovation Hubs
concluded.
New budget for the Bio-economy required
Some Bio-economy
successes
Previously reported:
•By 2014, the top 7 biotech companies had a combined annual turnover of
nearly R1 billion (from a direct investment of R63million);
•Eucalyptus Genome project – already providing cost savings to industry;
•Xsit – already providing additional income to the citrus industry;
•Umbiflow – providing for better maternal healthcare;
•mTriage – better emergency care.
New additions:
•10 IK-Based Cosmeceuticals (anti-acne, anti-eczema, anti-wrinkle, antiaging, skin toner, moisturisers and sun-screens) are ready for early
commercialisation;
•Access and benefit sharing agreement entered into with various
communities in Gauteng, Northern Cape, Western Cape, and Eastern
Cape;
•Five new patents filed from IKS technologies.
Ndo livhuwa
Enkosi
Thank you
Baie dankie
Siyabonga
Re a leboga
Ha Khensa
Enkosi Ditebo