College of Nursing

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College of Nursing
UNIVERSITY OF CENTRAL FLORIDA
COLLEGE OF NURSING
Spring 2014
Course Number:
NGR 6172
Course Title:
Pharmacology for Advanced Nursing Practice
Credit Hours:
3 (3, 0)
Prerequisites or Co-requisites: NGR 5141
(Pathophysiological Bases for Advanced Nursing Practice)
Students concurrently enrolled in a clinical practice course and
NGR 6192 who choose to withdraw from NGR 6172 MUST
also withdraw from the clinical practice course.
Catalog Description: Comprehensive study of medications used in the promotion and
maintenance of health across the lifespan. Examination of the implications for advanced nursing
practice. May be used in the degree program a maximum of 2 times.
Purpose: Introduce graduate nursing students to advanced pharmacological concepts employed
by advanced practice nurses across the lifespan.
Instructors: Christopher W. Blackwell, Ph.D., ARNP, ANP-BC, CNE
Associate Professor, College of Nursing
University of Central Florida
12201 Research Parkway
Orlando, FL 32826
(407) 823-2517 (office); (407) 823-5675 (fax)
(407) 375-4334 (personal cell) Office: UT: 453 (by appt.)
E-Mail: christopher.blackwell@ucf.edu
Meeting Time and Location: UT, Room 650A; Select R: 1330-1620
P.O. Box 162210  Orlando, FL 32816-2210  407-823-2744  FAX 407-823-5675
An Equal Opportunity and Affirmative Action Institution
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Course Objectives:
1. Integrate the concept of pharmacotherapeutics in the prevention and treatment of illness
in clients across the lifespan;
2. Apply nursing and related research in the use of pharmacologic agents;
3. Apply concepts of pharmacokinetics and pharmacodynamics in the selection and
monitoring of pharmacologic agents;
4. Discuss the ethical, legal, and professional aspects of advanced nursing practice roles in
relation to prescriptive authority and the roles of other health care team members;
5. Use knowledge of drug actions to predict possible adverse reactions, toxic effects, and
drug interactions associated with drugs used in the management of common health
problems;
6. Relate age, gender, pregnancy status, socioeconomic, psychosocial and cultural
considerations to the pharmacologic management of common health problem;
7. Incorporate use of a drug history and client knowledge of drug therapy in developing
interventions related to drug therapy.
Teaching/Learning Strategies:
Lecture
Class and Web based discussion
Reading
Written/ Group Assignments
Case Studies
Review and use of library and electronic resources
Examination
EVALUATION METHODS:
3 Proctored Examinations
1 Comprehensive Pharmacokinetics/ Pharmacodynamics Case Study
Attendance and Participation
Units of Instruction: (Note order of content in lecture will vary slightly. See course
schedule)*
I. Prescribing Practices, Patient Adherence, and Rational Drug Selection:
1. Florida NP Prescription Laws and Regulations
2. Patient Adherence and Compliance
3. Counterfeit Drug Laws
4. Information Technology and Pharmacotherapeutics; Safety in Pregnancy and
Lactation; and additional resources
5. Writing Prescriptions: How, What, and Legally Mandated Components
II. Pharmacokinetics and Pharmacodynamics
1. Basic Principles of Pharmacology
2. Adverse Drug Reactions & Interactions
3. Factors that Foster Positive Outcomes
4. Rational Drug Selection
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III. Pharmocogenetics, Pharmacoeconomics, OTCs, Herbals, and Supplements:
1. Cultural and Ethnic Influences in Pharmacotherapeutics
2. Pharmacogenomics
3. Nutrition and Nutraceuticals
4. Pharmacoeconmics
5. OTC Medications
6. Herbal and Complimentary Therapies
IV. Drugs Affecting the Hematapoietic System:
1. Anemias
2. Anticoagulants
3. Nutritional Fe+ supplements
3. Growth-Colonization Stimulating Factors (GCSF)
V. Drugs Affecting the Endocrine System:
1. Diabetes Mellitus
2. HRT and Osteoporosis
3. Hyperthyroidism and Hypothyroidism
4. Hyperparathyroidism
VI. Drugs Affecting the Integumentary System:
1. Dermatological Conditions
VII. Drugs Affecting the Neurological System and Drugs Used to Treat Psychiatric
Disturbances:
1. Anxiety and Depression
2. Mood Disorders
3. Dementia
4. Psychosis
5. Pain Management: Acute and Chronic
6. Headaches
7. Smoking Cessation
8. ETOH Cessation
VIII. Drugs Affecting the Gastrointestinal System:
1. Inflammatory Bowel Diseases
2. Gastric Esophageal Reflux Disease (GERD)
3. Peptic Ulcer Disease (PUD)
IX. Drugs Affecting the Respiratory System:
1. Asthma and COPD
2. Pneumonia
3. Tuberculosis
4. Upper Respiratory Infections
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X. Anti-Infectives and Resistance:
1. Drugs Used to Treat Infectious Diseases
2. Basic Principles of Antibiotics
3. Drug Resistance
4. Methicillin-Resistant Staph. aureus
5. Carbapenam resistant Klebsiella
XI. Drugs Affecting the Cardiovascular and Renal Systems:
1. Chronic and Acute Stable/ Low-Risk Angina
2. Heart Failure
3. Hyperlipidemia
4. Hypertension
XII. Drugs Affecting the Musculoskeletal System:
1. Muscle Relaxants and Anti-Inflammatories
2. Drugs used to treat OA
3. Drugs used to treat RA
XIII. Drugs Affecting the Immune System:
1. Corticosteroids
2. Immunomodulators
3. Biologicals
4. HIV/ AIDS
XIV. Drugs Affecting the Reproductive System:
1. Contraception and Pregnancy Prevention
2. Sexually-Transmitted Infections
3. Vulvo-Vaginitis
3. Urinary Tract Infections
4. Prostate, Testicular, and Penile Conditions
*- Note, this course does not cover the diagnostic process or management of any disease process.
Drugs and other medicinal interventions used to treat diseases will be covered and will include
classes of drugs and other specific pharmacological interventions used as part of the management
of acute and chronic illnesses.
Required Text
Woo, T. M. & Wynne, A.L. (2011). Pharmacotherapeutics for nurse practitioner prescribers
(3rd ed.) Philadelphia, PA: F.A. Davis.
Textbook ISBN: 97808362235
Recommended Textbooks:
Gilbert, et al. (2012). The Sanford guide to antimicrobial therapy 2012 (42nd Ed.). Sperryville,
VA: Antimicrobial Therapy, Inc.
Textbook ISBN: 978-1930808706 [also available for mobile devices]
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Recommended Technology:

Apple iPhone, iTouch, or Android device with the following Apps downloaded: Monthly
Prescriber’s Reference, MedScape, WebMD, Epocrates (all are free)
Course Schedule:
Date
January 9, 2014 (Live)
Guest Lecturer:
Jonathan Decker, Ph.D.,
ARNP, FNP-BC
January 16, 2014 (WWW)
January 23, 2014 (Live)
January 30, 2014 (WWW)
February 6, 2014 (Live)
Content
I. Prescribing Practices,
Patient Adherence, and
Rational Drug Selection:
1. Florida NP Prescription
Laws and Regulation
2. Patient Adherence and
Compliance
3. Counterfeit Drug Laws
4. Information Technology
and Pharmacotherapeutics
5. Writing Prescriptions:
How, What, and Legally
Mandated Components
Assignment
Woo & Wynne (2011):
II. Pharmacokinetics and
Pharmacodynamics
1. Basic Principles of
Pharmacology
2. Adverse Drug Reactions
3. Factors that Foster
Positive Outcomes
4. Rational Drug Selection
II. Pharmacokinetics and
Pharmacodynamics
1. Basic Principles of
Pharmacology
2. Adverse Drug Reactions
3. Factors that Foster
Positive Outcomes
4. Rational Drug Selection
Woo & Wynne (2011):
II. Pharmacokinetics and
Pharmacodynamics
1. Basic Principles of
Pharmacology
2. Adverse Drug Reactions
3. Factors that Foster
Positive Outcomes
Chapters: 1, 4, 11
Chapters: 2, 3, 5, 6
Woo & Wynne (2011):
Chapters: 2, 3, 5, 6
Woo & Wynne (2011):
Chapters: 2, 3, 5, 6
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4. Rational Drug Selection
February 13, 2014 (WWW)
February 20, 2014 (Live)
February 27, 2014 (WWW)
March 13, 2014 (Live)
III. Pharmocogenetics,
Pharmacoeconomics,
OTCs, Herbals, and
Supplements:
1. Cultural and Ethnic
Influences in
Pharmacotherapeutics
2. Pharmacogenomics
3. Nutrition and
Nutraceuticals
4. Pharmacoeconmics
5. OTC Medications
6. Herbal and
Complimentary Therapies
Woo & Wynne (2011):
IV. Drugs Affecting the
Hematapoietic System:
1. Anemias
2. Anticoagulants
3. Nutritional Fe+
supplements
4. Growth-Colonization
Stimulating Factors
(GCSF)
V. Drugs Affecting the
Endocrine System:
1. Diabetes Mellitus
2. HRT and Osteoporosis
3. Hyperthyroidism and
Hypothyroidism
Woo & Wynne (2011):
VI. Drugs Affecting the
Integumentary System:
1. Dermatological
Conditions
VII. Drugs Affecting the
Neurological System and
Drugs Used to Treat
Psychiatric Disturbances:
1. Anxiety and Depression
2. Dementia
3. Psychosis
2. Pain Management: Acute
and Chronic
3. Mood Disorders
Chapters: 7, 8, 9, 10, 12, 13
Chapters: 18, 27
Woo & Wynne (2011):
Chapters: 21, 33, 38, 41
Exam I: Covers Units I-IV
Thursday, February 13, 2014;
1330- 1510
Woo & Wynne (2011):
Chapters: 23, 32
Woo & Wynne (2011):
Chapters: 14, 15, 29, 35, 43
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4. Headaches
5. Smoking Cessation
6. ETOH Cessation
March 20, 2014 (Live)
March 27, 2014 (WWW)
April 3, 2014 (WWW)
April 10, 2014 (Live)
VIII. Drugs Affecting the
Gastrointestinal System:
1. Inflammatory Bowel
Diseases
2. Gastroesophageal Reflux
Disease (GERD)
3. Peptic Ulcer Disease
IX. Drugs Affecting the
Respiratory System:
1. Asthma and COPD
2. Pneumonia
3. Tuberculosis
4. Upper Respiratory
Infections
Woo & Wynne (2011):
X. Anti-Infectives and
Resistance:
1. Drugs Used to Treat
Infectious Diseases
2. Basic Principles of
Antibiotics
3. Drug Resistance
4. Methicillin-Resistant
Staph. Aureus
5. Carbapenan resistant
Klebsiella
XI. Drugs Affecting the
Cardiovascular and Renal
Systems:
1. Chronic and Acute
Stable/ Low-Risk Angina
2. Heart Failure
3. Hyperlipidemia
4. Hypertension
Woo & Wynne (2011):
XII. Drugs Affecting the
Musculoskeletal System:
1. Muscle Relaxants and
Anti-Inflammatories
2. Drugs Used to Treat OA
and RA
Woo & Wynne (2011):
Chapters: 20, 34
Woo & Wynne (2011):
Chapters: 17, 30, 42, 45, 46
Chapters: 24, 42, 45, 46
Exam II: Covers Units V-X
Thursday, March 27, 2014;
1330- 1530
Woo & Wynne (2011):
Chapters: 16, 28, 36, 39, 40
Chapters: 25
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April 17, 2014 (Live)
April 24, 2014
XIII. Drugs Affecting the
Immune System:
1. Corticosteroids and
Immunomodulators
2. HIV/ AIDS
Woo & Wynne (2011):
XIV. Drugs Affecting the
Reproductive System:
1. Contraception and
Pregnancy Prevention
2. Sexually-Transmitted
Infections and Vaginitis
3. Urinary Tract Infections
4. Prostate, Testicular and
Penile Conditions
Exam #3
Woo & Wynne (2011):
Chapters: 25, 37
Chapters: 31, 44, 47, 49
Exam III: Covers Units XIXIV Thursday, Apr 24, 2014;
1330- 1510
EVALUATION METHODS
Examination #1
40 points
Examination #2
60 points
Examination #3
40 points
Comprehensive Pharmacokinetics and Pharmacodynamics Case Study
50 points
Attendance and Participation
10 points
______________________________________________________________________________
Total
200 points
Grading System:
96-100
92-95
87-91
83-86
79-82
75-78
70-74
69 or below
A
AB+
B
C+*
C*
D*
F*
Points
191 - 200
183 - 190
173 - 182
165 - 172
157 - 164
149 - 156
139 - 148
0 - 138
* - Not acceptable for progression in the Master of Science in Nursing or Doctor of Nursing
Practice Programs.
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Academic Progression, Description of Course Assignments, and Course Policies:
Academic Progression: An average of 75% must be earned on course examinations to
successfully pass this course. Any student with a final course exam average less than 75%
will not have any other course assignments (including extra credit, when available)
calculated in the final grade and cannot progress in the Doctor of Nursing Practice or
Master of Science in Nursing programs in the College of Nursing.
Proctored Examination (40, 60, and 40 points): Students will complete 3 examinations (see
course schedule) that will be proctored through the ProctorU Examination Proctoring Service.
Each exam consists of materials covered in each Unit of the course. And each exam will have 10
questions per Unit covered on the exam (40, 60, and 40 questions respectively for each exam).
Students will have 2 minutes per question. The exams are closed note, closed book, closed
Internet. NO sources either than the student’s own individual knowledge can be used
during the completion of the exams.
Comprehensive Pharmacodynamics and Pharmacokinetics Case Study: Students will be
placed into groups and will be responsible for completing one comprehensive case study that will
provide a detailed discussion of the pharmacodynamics and pharmacokinetics of a particular
medication drug class. Each member of the group is graded individually. Therefore, students
must demonstrate adequate participation in the assignment. While items in the case study are
broad, students are encouraged to contact the instructor for any direction regarding completion of
the questions. Grading for the assignment will be based on the following rubric:
Item
Possible Points Points Earned
Answers are complete and comprehensive
10
Answers are applied to a clinical scenario and are clinically
10
appropriate to the primary care setting
Responses are provided using most recently available
10
evidence based guidelines
Resources provided are recent (Most no more than 5 years
5
old or no more than 10 years old where appropriate)
Paper is formatted according to and all cited references meet
10
th
APA 6 Edition criteria
Evidence of substantial input into the assignment
5*
Body of assignment is no more than 5 pages in length,
-10
double-spaced using Times New Roman (minus the title and For every 10
reference pages)
words over 5
pages
* = Students who fail to demonstrate substantial input into the assignment will earn a 0 on the
assignment.
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Comprehensive Pharmacodynamics and Pharmacokinetics Case Study Schedule:
Unit(s)
IV. Drugs Affecting the Hematapoietic System:
1. Anemias
2. Anticoagulants
3. Nutritional Fe+ supplements
4. Growth-Colonization Stimulating Factors (GCSF)
V. Drugs Affecting the Endocrine System:
1. Diabetes Mellitus
2. HRT and Osteoporosis
3. Hyperthyroidism and Hypothyroidism
VI. Drugs Affecting the Integumentary System:
1. Dermatological Conditions
VII. Drugs Affecting the Neurological System and Drugs Used to Treat
Psychiatric Disturbances:
1. Anxiety and Depression
2. Dementia
3. Psychosis
2. Pain Management: Acute and Chronic
3. Mood Disorders
4. Headaches
5. Smoking Cessation
6. ETOH Cessation
VIII. Drugs Affecting the Gastrointestinal System:
1. Inflammatory Bowel Diseases
2. Gastroesophageal Reflux Disease (GERD)
3. Peptic Ulcer Disease
IX. Drugs Affecting the Respiratory System:
1. Asthma and COPD
2. Pneumonia
3. Tuberculosis
4. Upper Respiratory Infections
Due Date*
2/5/14
2/19/14
3/12/14
3/19/14
X. Anti-Infectives and Resistance:
1. Drugs Used to Treat Infectious Diseases
2. Basic Principles of Antibiotics
3. Drug Resistance
4. Methicillin-Resistant Staph. Aureus
5. Carbapenan resistant Klebsiella
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An Equal Opportunity and Affirmative Action Institution
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XI. Drugs Affecting the Cardiovascular and Renal Systems:
1. Chronic and Acute Stable/ Low-Risk Angina
2. Heart Failure
3. Hyperlipidemia
4. Hypertension
XII. Drugs Affecting the Musculoskeletal System:
1. Muscle Relaxants and Anti-Inflammatories
2. Drugs Used to Treat OA and RA
XIII. Drugs Affecting the Immune System:
1. Corticosteroids and Immunomodulators
2. HIV/ AIDS
4/9/14
4/16/14
XIV. Drugs Affecting the Reproductive System:
1. Contraception and Pregnancy Prevention
2. Sexually-Transmitted Infections and Vaginitis
3. Urinary Tract Infections
4. Prostate, Testicular and Penile Conditions
* = All case studies must be posted to the appropriate discussion board no later than 2355
of the date listed above.
Attendance/ Participation (10 points): Students are expected to arrive promptly to class on the
8 days the course is scheduled to meet live (see course schedule, above). In addition, students are
expected to remain in class for the entire meeting session (3 hours) and are required to participate
in any on-line initiated discussions. Attendance at each session is worth approximately 1.25
points. Students are also expected to arrive to the live class sessions prepared for discussion and
are expected to complete any assigned reading assignments before the class meeting. In addition,
any additional readings and/or resources posted to the WebCourses site should be read and
reviewed prior to the class meetings.
Missed Examinations: It is not advisable to miss an examination. The makeup examination
and/or assignment may be different than the original exam and could consist of multiple choice,
matching, and/or essay style questioning. The instructor(s) can also require additional work such
as research assignments, essays, or other work in addition to the examination substitution.
Students who do not notify the instructor of a missed assessment within 2 hours of the exam
closure time will forfeit makeup and receive a 0 score. All makeup assessments are taken at the
instructor’s discretion and are administered live on the Orlando campus.
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Update Your Profile
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American Nurses Association
The Code of Ethics for Nurses 2001
Voted on and accepted by the ANA House of Delegates on June 30, 2001
1. The nurse, in all professional relationships, practices with compassion and respect for
the inherent dignity, worth, and uniqueness of every individual, unrestricted by
considerations of social or economic status, personal attributes, or the nature of health
problems.
2. The nurse's primary commitment is to the patient, whether an individual, family, group, or
community.
3. The nurse promotes, advocates for, and strives to protect the health, safety, and rights of the
patient.
4. The nurse is responsible and accountable for individual nursing practice and determines the
appropriate delegation of tasks consistent with the nurse's obligation to provide optimum patient
care.
5. The nurse owes the same duties to self as to others, including the responsibility to preserve
integrity and safety, to maintain competence, and to continue personal and professional growth.
6. The nurse participates in establishing, maintaining, and improving health care environments
and conditions of employment conducive to the provision of quality health care and consistent
with the values of the profession through individual and collective action.
7. The nurse participates in the advancement of the profession through contributions to practice,
education, administration, and knowledge development.
8. The nurse collaborates with other health professionals and the public in promoting
community, national, and international efforts to meet health needs.
9. The profession of nursing, as represented by associations and their members, is responsible for
articulating nursing values, for maintaining the integrity of the profession and its practice, and
for shaping social policy.
The Code of Ethics for Nurses is available for sale from American Nurses Publishing at
1-800-637-0323 or www.nursesbooks.org
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Office of Student Rights and Responsibilities
University of Central Florida
YOUR ENROLLMENT STATUS MAY BE AT RISK!
Academic Dishonesty in any form will not be tolerated!!!
The University of Central Florida has recently started an account with turnitin.com., an
automated system which instructors can use to quickly and easily compare each student's report
to billions of web sites, as well as an enormous database of student papers that grows with each
submission. After submission of the paper, instructors receive a report that states if and how
another author's work was used.
Violations of student academic behavior standards are outlined in The Golden Rule, the
University of Central Florida's Student Handbook. See http://www.ucf.edu/goldenrule/ for
further details.
1. Cheating whereby non-permissible written, visual or oral assistance including that obtained
from another student is utilized on examinations, course assignments or projects. The
unauthorized possession or use of examination or course related material shall also constitute
cheating.
2. Plagiarism whereby another's work is deliberately used or appropriated without any indication
of the source. Thereby attempting to convey the impression that such work is the student's
own. Any student failing to properly credit ideas or materials taken from another has
plagiarized.
3. A student who has assisted another in any of the aforementioned breach of standards shall be
considered equally culpable.
ACADEMIC ACTION
* Taken by Instructor, Chair, or Dean of College*
1. Counseling
2. Loss of credit for specific assignment, examination or project.
3. Removal from course with a grade of "F" and/or
CONDUCT REVIEW ACTION
*Taken by the Office of Student Conduct*
1. Warning
2. Probation
3. Suspension
4. Expulsion
5. Permanent conduct record with UCF accessible by other institutions by request.
For more information, please contact the Office of Student Conduct at 823-2851.
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Persons With Disabilities: The University of Central Florida is committed to
providing reasonable accommodations for all persons with disabilities. Students who need
accommodations must be registered with Student Disability Services (SDS), Student Resource
Center Room 132, phone (407) 823-2371, TTY/TDD only phone (407) 823-2116, before
requesting accommodations from the professor. Students who are registered with SDS and need
accommodations in this course must contact the professor at the beginning of the semester to
discuss needed accommodations. No accommodations will be provided until the student has met
with the professor to request accommodations. This syllabus is available in alternate formats
upon request.
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