Lab: Immune and Lymphatic Systems
NAME________________________ PER_____
Lymphatic Organs and Tissues
1. The lymphatic system is a specialized subdivision of the circulatory system. Although the cardiovascular
system has a pump (the heart) and arteries, veins, and capillaries, the lymphatic system lacks two of these
structures: the ______________ and the ___________. Like the ___________ of the cardiovasculae
system, the vessels of the lymphatic system are equipped with _________ to prevent backflow. The
lymphatic vessels act primarily to pick up leaked fluid, now called _________, and return it to the
bloodstream. About _______ of fluid is returned every 24 hours.
2. Label the following diagram using these terms:
axillary node, appendix, right lymphatic duct, thymus gland, pharyngeal tonsils, inguinal nodes, Peyer’s
patches, intestinal nodes, red bone marrow, mammary plexus, cervical nodes, thoracic duct, spleen
3. Choose one of the following slides: lymph node, thymus, spleen, or tonsil. Examine it under the
microscope and draw what you see in color. Label the major structures as well.
Slide:____________________
Magnification:_______
4. Match the term to the description.
___The largest lymphatic organ
___ Filter lymph
___ Particularly large and important during youth; produces hormones that
help to program the immune system
___ Removes aged and defective red blood cells
___ Includes the adenoids
___ Acts against bacteria breaching the intestinal wall
___ Lack a complete capsule and have crypts in which bacteria can be trapped
A.
B.
C.
D.
E.
Lymph node
Peyer’s patches
Spleen
Thymus
Tonsils
5. The figure below provides an overview of the lymphatic vessels. In part A, the relationship between
lymphatic vessels and the blood vessels of the cardiovascular system is depicted schematically. Part B show
the different types of lymphatic vessels in a simple way. First, color code and color the following:
Heart
Arteries
Veins
Blood capillaries
Lymphatic vessels/ lymph node
Loose connective tissue around
the blood and lymph capillaries
6. Then, identify by labeling these specific structures in part B:
Lymph capillaries, lymph duct, lymphatic collecting vessels, lymph trunks, lymph node, valves, veins
Immune Cells and Response
7. The major elements of the body’s nonspecific defense system are: the ___________, consisting of the skin
and ________; defensive cells, such as _____________ and phagocytes; and a whole deluge of __________.
8. The basic structure of an antibody is diagrammed below. Select 2 different colors and color the heavy
chains and the light chains. Add labels to the diagram to identify the type of bonds that hold the polypeptide
chains together, the complement binding site, and the macrophage binding site. Also label the constant (c)
and the variable (v) regions of the antibody, adding polka dots to the variable portions.
Which part of the antibody, v or c,
is its antigen binding site? _____
Which part determines antibody
class and specific function? ______
9. The figure below diagrams the events involved in the inflammatory response. Events depicted in A
precede those shown in B. Each event is represented by a square with one or more arrows. From the list
below, write the correct number in each event square in the figure. Then, color code and color the
structures that appear in the numbered list.
1.
2.
3.
4.
5.
6.
7.
8.
WBCs are drawn to the injured area by the release of inflammatory chemicals.
Tissue repair occurs.
Tissue injury occurs and microbes enter the injured tissues.
Local blood vessels dilate and the capillaries become engorged with blood.
Phagocytosis of microbes occurs.
Fluid containing clotting proteins is lost from the bloodstream and enters the injured tissue area.
Mast cells degranulate, releasing inflammatory chemicals.
Margination and diapedesis occur.
Mast cells
Mast cell granules
Monocyte
Epithelium
Erythrocytes
Neutrophils
Macrophage
Subcutaneous tissue
Endothelium of capillary
Microorganisms
Fibrous tissue repair
10.Use the following terms to complete the concept map on the Immune System.
Active immunization, transfer of antibodies, acquired, nonspecific immunity, inflammation, passive
immunization, active, phagocytic cells, specific immunity, innate
11.Fill in the blank to describe the type of immune cell.
Killer T cells, antibodies, natural killer cells, viruses, helper T cells, suppressor T cells, B cells,
macrophages, memory T and B cells