Mendelian Genetics Objectives (Chapter 14)

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Mendelian Genetics Objectives (Chapter 14)

After

reading this chapter

and attending class (and actively participating), you should be able to:

1.

Explain Mendel's theory of inheritance

2.

State and explain the Law of Segregation

3.

Distinguish between: genotype and phenotype, heterozygous and homozygous; and dominant and recessive

4.

Use a Punnett Square to predict the results of a monohybrid cross and state the phenotypic and genotypic ratios of the F2 generation

5.

Explain how a testcross can be used to test whether a dominant phenotype is homozygous or heterozygous

6.

Define the concept "random event" and explain why it is significant that allele segregation during meiosis and fusion of gametes at fertilization are random events

7.

Apply the "multiplication" rule to predicting probabilities of specific outcomes from genetic crosses

8.

Apply the "addition" rule to predicting probabilities of specific outcomes from genetic crosses

9.

Use a Punnett Square to predict the results of a dihybrid cross and state the phenotypic and genotypic ratios of the F2 generation

10.

Predict the results of genetic crosses involving three or more unlinked genes

11.

Give an example of incomplete dominance and explain how it differs from "blending inheritance"

12.

Describe inheritance within the ABO blood group system

13.

Define and give an example of pleiotropy

14.

Explain what is meant by the phenomenon of epistasis

15.

Describe how environmental factors can influence the phenotypic expression of a character

16.

Deduce the genotypes for family members when presented with a simple pedigree

17.

Explain how a lethal recessive gene can be maintained within a population

18.

Explain why lethal dominant genes are more rare than lethal recessive genes

19.

Give and example of a late-acting lethal dominant in humans and explain how it can escape elimination

20.

Explain why consanguinity increases the probability of homozygosity in offspring

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