LISTS
CONTACT DERM
PABA Cross rxn
Procainamide/PPD
Aminosalicylic Acid; azo/aliline dyes
Sulfonamides/sulfonylureas
Thiazides
Ester anesthetics: benzocaine, cocaine, procaine,
tetracaine
Latex cross rxn
Passion fruit
Banana
Avocado
Chestnut
Kiwi
Poison Ivy cross rxn
(same family; similar antigens)
Little—lacquer tree
Ginko (fruit pulp)
Mango (peel)/ Marking nut
Chashew shell
Balsam of Peru cross rxn
Curry
Cloves
Cinnamon
Colophony
Terpentine
Benzoin
Vanilla
1
LISTS
2
GENODERMATOSES
X-linked recessive Usually gene defect
Fabry’s
Ehler’s-Danlos
Wiskott-Aldrich
Hunter’s
Ichythosis, X-linked
Dyskeratosis congenita
Ectodermal dysplasia, anhidrotic type
Behind—Bruton’s
Massive--Menke’s
CGD
Calcifications in CNS
Cockayne Syndrome-basal ganglia
Lipoid proteinosis-sickle shaped hippocampus
Albright’s-basal ganglia
Sturgg-Weber-tram track
Papillion LeFevre-dura
Gorlin’s-falx
Tuberous sclerosis-periventricular
Dyskeratosis Congenita-basal ganglia
X-linked dominant: Usually a protein defect
Focal dermal hypoplasia of Goltz
IP
Conradi-Hunermann
CHILD
Albright’s
Bazek’s
Sister chromatid exchange
Ataxia-telangectasia (Break)
Blooms (both)
Cockayne (both)
Dyskeratosis Congenita (Exchange)
Fanconi’s (both)
Gardner’s (both)
Colloidian Baby
CIE #1
Sjogran-Larson
Hay-wells
Idiopathic
Netherton’s/ Neutral lipid storage dz
Lamellar icthyosis
Goshay’s Type 2?
Ectodermal dysplasia
Lipid Vacoules
Sjogren-Larson-keratinocytes
Refsum-basal kertinocytes
NLSD-everywhere (eos, monos, etc)
Retinitis Pigmentosa
Refsum-typical
Cockaynes-typical
Sjogren-Larson-atypical
Refsum Syndrome
Vacoules in keratinocytes
Arrhythmias
Cerebellar ataxia
Polyneuropathy/inc phytanic acid
Retinitis pigmentosa
Sensorineural deafness
Conradi-Hunermann
Cataracts/chondrodysplasia punctata
Ortho problems
Nasal root flattening
Rhyzomelic dwarfism (PEX7)
Alopecia
Defect in EBP
Icthyosiform Erythroderma
Transgradiens
Mal de Meleda
Papillion-LeFevre
Cloustons?
Naxos
Olmstead
Greither?
Hereditary palmar/plantar hyperkeratosis HUMP
Howell-Evans
Unna-Thost (most prevalent)
Mal de Meleda
Papillion - LeFevre
Café au lait macules
NFI/II
McCune Albright
Tuberous Sclerosis
Noonan Syndrome
NF-I Criteria (2 or more)
First degree relative
Axillary freckling
Lisch nodules (2+)
Café-au-lait macules (6+)
Optic glioma
NF (2+ or 1 plexiform)
Sphenoid wing dysplasia/thinning of long bone
LISTS
Enamel Pits
Tuberous Sclerosis
Focal Dermal Hypoplasia of Goltz
Junctional EB
PTEN mutation
Proteus Syndrome
Cowdens
Bannayan-Riley-Ruvalcaba
Lhermitte-Duclos
Oral cobblestoning ddx
Men—MEN 2b
And
Cows—Cowden’s
Croon—Crohn’s
Over
Little—Lipoid proteinosis
Pixie’s—PXE
Darier—Darier’s
Ataxia-Telangectasia
Ataxia-1st sign
Telangectasia
A IgA defieciency
Xray sensitivity
Immune deficiency
AFP/CEA increased
Thymus abnormalities
E IgE def
Lymphoma/Leukemia
Absent ovaries/testes
DNA helicase disorders
Werners
Blooms
Xeroderma Pigmentosa types B, D, and G
Rothman-Thomson
Cockaynes
Thrichothiodystropy
3
LISTS
DRUG RELATED
Drug related pimentation
Blue/black- Minocycline/Plaquenil/chloroquine
Slate gray-Argyria, amiodarone, chlorpromazine
Lilac-Gold (eyelids)
Yellow-Quinaqrine
Red brown- Hemosiderin/clofazimine
Hypersensitivity reactions
Hepatomegaly
Arene oxide metabolites
LAD, leukocytosis
Fever, facial edema
Splenomegaly
Pneumonitis
LFT’s
Eosinophilia
Epoxide hydrolase deficiency
Nephritis
Lupus drugs +anti-histone Ab
Sulfa drugs
Tetracylcine
OCP
Penicillamine
Griseofulvin
Chlorpromazine
Hydralazine
INH
Minocycline
Procainamide
Lichenoid Drugs
B-blocker
Y
The—Thiazides
Gold
ACE-inhibitor, antimalrials
Penicillamine
Sulfonamides
Psoriasis exacerbation
B-blocker
Lithium
IFN
Plaquenil
Hydroxyurea
Dermatomyositis of hands
Leg ulcers
Photosensitivity
Demeclocycline > Doxy > Tetra > Minocycline
4
Hypertrichosis
1. Cyclosporine
2. IFN
3. Minoxidil
4. Dilantin
Gingival hyperplasia
1. Cyclosporine
2. Calcium-channel blocker
3. Phenytoin
4. Leukemia
Acneiform eruptions
1. Halogenoderma
2. Lithium
3. Steroids
4. Dilantin
5. INH
Pityriasis Rosea Drugs AA,BB,CC,GG,F, PP
Arsenic, Aspirin
Bismuth, Barbiturates
Clonidine, Captopril
Gold, Gresiofulvin
Flagyl
Plaquenil, Penicillamine
SCLE drugs:
Statins
Calcium-channel blockers
Griseofulvin
IFN
Terbinafine/Thiazides
Etanercept
Drug induced Pemphigus CRAP PCP
Captopril
Rifampin
ACE inhibitors
Piroxicam
Penicillin
Cephalosporins
Penicillamine
LISTS
LOCATION
Anterior shin DDx
Hypertrophic LP
Erythema nodosum
Lichen amyloid
LDS/stasis dermatitis
Myxedema
Elephantiasis
NLD
Leonine facies DDx:
Pachyderma periostosis
Amyloidosis
Leprosy
MF
Scleromyxedema
Paget’s disease of bone
Chronic actinic dermatosis
Ear involvement
Lovely-Leoprosy
Girls-Gout
Do-DLE
Pierce-Pneumocystis
C--CNH
EED
ALHE
RP
Nasal destruction ddx
1. Rhinoscleroma
2. Leishmaniasis
3. Lethal midline granuloma
4. Leprosy
5. Tertiary syphilis
6. TB
7. Mucormycosis
8. Aspergillus
9. Paracoccidioidomycosis
10. Wegener’s
Periorbital DDx
1. Syringoma
2. Hidrocystoma
3. Sebaceous carcinoma
4. Sarcoid
5. DPN
6. Lipoid proteinosis
7. NXG
8. Xanthelasma
9. Chalazion
10. Primary signet ring CA
5
Blue Sclerae (Osler’s sign)
Osteogenesis Imperfecta
Ehlers Danlos
Wilsons dz
Alcaptonuria
Pseudohypoparathyroidsm
Russell-Silver syndrome
LISTS
INFECTION
Ectothrix: + Fluorescence on Wood’s light
Cats—M. canis
And—M. audouinii
Dogs—M. Canis distortum
Fight—M. ferrugineum
Outside
Endothrix: - Fluorescence
Keep Your TV’s inside
T—T. tonsurans
V—T. violaceum
S—T. soudanense
5 red copper pennies: Medlar (sclerotic) bodies of
Chromoblastomycosis
1. Fonsacea (#1)
2. Rhinocladiella (red)
3. Cladosporidium
4. Philaphora
5. Exophilia
Intracytoplasmic bodies:
Pete—Penicillium marnefii
Likes—Leishmaniasis (small, has kinetoplast),
Leprosy (virchow cells)
Toxic—Toxo
Gin—Granuloma inguinale (Donovan bodies)
Rum—Rhinoscleroma (Mickulicz cells, Russell
bodies of plasma cells)
Martinis—Malakoplakia (E. coli—Von Hansemann
macrophages with Michealis-Gutmann
bodies)
And—atypical MB
Ham—Histoplasmosis (small as Leishmania, but
No kinetoplast)
Angioinvasive ddx:
1. Mucormycosis
2. Aspergillus
3. Nocardia
Sporotrichoid spread ddx
Sporothrix
Anthrax
Tularemia
Atypical MB/TB
Nocardia
Streptobacillus monoliformis
Leishmania
Glander’s
Bartonella henselae
Dimorphic fungi
Mycetoma
Chromoblastomycosis
Syphilis
6
Stellate abscesses on histopath:
Lymphogranuloma venereum
Cat-scratch dz
Atypical mycobacteria
Tularemia
Sporotrichosis
LISTS
DERMPATH
Mucin stains:
1. Alcian blue (stains hyaluronic acid >pH 2.5
or sulfated mucin at any pH)
2. Colloidal iron
3. Toluidine blue
Papillary dermal edema
Sweet
Charlotte—Cellulitis
Bites
Pretty—PMLE, Pernio
Ladies—LCV
Neutrophilic abscesses in thick epidermis
1. Deep fungal (chromo, blato, sporo)
2. KA
3. Halogenoderma
4. Pemphigus vegetans
Palisading granulomas with “stuff”
1. GA
2. NXG
3. NLD
4. Rheumatoid nodule
5. Actinic elastolytic granuloma
6. TB
Palisading granulomas with “cells”
Sperms in the derm /”Paisley Tie”(ducts)
1. Morpheaform BCC
2. Syringoma
3. Breast CA, Metastatic
4. Microcystic adnexal carcinoma (MAC)
5. Desmoplastic trichoepithelioma
Eosinophilic spongiosis
Herpes gestationis
Arthropod bites
Pemphigus
Pemphigoid
IP—vesicular, 1st stage
Allergic contact
Tinea
Milker’s nodule
Scabies
Wedge-shaped ddx
PLEVA
LYP
Arthropod bites
Degos (necrosis)
7
Grenz zone
Acrodermatitis chronica atrophicans
Colloid milium
Granuloma faciale
Leprosy
Leukemia/lymphoma
Sarcoid
DF
Clumped tonofilaments
Dowling Meara EBS
Voyner’s
PPK
Erythrokeratoderma variabilis
Friction blister
EHK
Clark’s levels: measure from top of granular layer or
bottom of an ulcer
1. In situ
2. Papillary dermis
3. Filling/expanding papillary dermis
4. Reticular dermis
5. Fat
Cup-shaped ddx:
Mark-molluscum
Steven-syringocystadenoma papilliferum
King-KA
Dilated pore of Winer
Warty dyskeratoma
IFK
Church spiring:
Verruca Vulgaris
ILVEN
SK
Acrokeratosis verruciformis/AN
Clear cells:
1. Clear cell SCC
2. BCC
3. Sebaceous carcinoma
4. Balloon cell carcinoma
5. Clear cell acanthoma
6. Clear cell hidradenoma
7. Clear cell syringoma (assoc w/ DM)
8. Trichilemmoma
9. Renal Cell CA
LISTS
8
No granular layer
Psoriasis
Ichthyosis vulgaris
Mucous membranes
Pachyonychia congenital
Clavus
Clear cell acanthoma
GVHD staging
Nausea, grade 0 (no changes)
Vomiting, grade 1 (vacuolar changes)
Diarrhea, grade 2 (dyskeratotic cells)
Cramping grade 3 (clefting)
S _______ grade 4 separation
Busy Dermis
1. NFD
2. Interstitial GA
3. Scleroderma/scleredema/-myxedema?
4. metastatic breast CA
5. Leukemia/lymphoma
6. DF (edge)
7. Kaposi’s sarcoma
8. Resolving LCV
Sub-corneal Pustules (SPASTIC)
Sneddon Wilkinson
Pemphigus Foliaceus
AGEP (acute gen. exanthemous pustulosis)
Scabies
Tinea
Impetigo ?IgA Pemphigus
Candida
Plasma cells b/w dermis & fat:
1. Scleroderma
2. NLD
3. Lupus panniculitis
4. Kaposi’s sarcoma
5. Granuloma inguinale
Elastosis Perfans Serpiginosa MADROPPE
Marfans
Acrogyria
Down’s syndrome
Rothman-Thomsom syndrome
Osteogenesis Imperfecta
PXE (pseudoxanthoma elasticum)
Penacillamine use in Wilson’s dz
Ehlers – Danlos syndrome
Filling the papillary dermis
Lichenoid diseases
Urticaria pigmentosa
MF
PPD’s
Spindle Cells
DF
DFSP
Kaposi’s-Promontory sign->plasma cells around BV
Leiomyoma
Sarcoma
Melanoma
peri-eccrine differential:
w/interface
LUPUS
Lichen striatus
Syphilis
MF
w/o interface
perniosis
PMLE
Leukocytoclastic vasc. causes VASCULITIS
Viral (Hep B&C)
Anaphylactoid purpura, autoimmune(SLE,DM)
Staph, strep, sepsis, menengiococcus, DIC
Cryoglobulins
Urticarial vasculitis, Ulcerative colitis
Lymphoproliferative dz (hairy cell leukemia)
Idiopathic
Thiazides, phenothiazides, lasix
Immune sera, iodides
Sulfa, penicillin, other abx
LISTS
Interface dermatitis CDEFGH VVLP
Connective tissue dz (LE, DM)
Drug eruption
Erythema Multiforme
Fixed drug
GVHD
HIV
Vitiligo
Viral exanthema
Lichen sclerosis (early)
Pityriasis Lichenoides
Hemosiderin stains
Perls
Prussian blue
Ferricyanide
Too High Fat NASA GAP
Nevus lipomatosis
Ancient nevus
Scar/skin tag
Aplasia cutis
Goltz synd (focal dermal hypoplasia)
Accessory tragus
Painful piezogenic pedal papules
coronoid lamellae differential
eccrine ostial nevus
Porokeratosis
Pseudoepithilomatous hyperplasia
Edge of an ulcer
Granular cell tumor
Pemphigus vegetans
Chromoblastomycosis
Blastomycosis
Sporo
Halogenoderma
Small Blue cells GMC be slop
Glomus tumor
Merkel cell
Cylindroma
Basal cell
Ewings sarcoma
Spirademoma
Lymphoma
Oat cell tumor
PNET (Ewings spectrum)
9
Psammoma bodies
(mammilated basophilic concretions)
Meningioma
Papillary thyroid cancer
Ovarian cancer
Nevocellular nevus
Melanotic schwannoma
Acantholysis list
PF, PV
Grovers, Hailey-Hailey, Dariers
Acantholytic SCC
Acantholytic AK
Warty dyskeratosis
LISTS
10
CLINICAL
Xray sensitivity
Ataxia-Telangectasia
XP
Gorlin’s
Epidermodysplasia Verruciformis
Verrucous CA
Giant Condyloma
Erythroderma
1. Idiopathic (50%)
2. Psoriasis (erythrodermic)
3. Seb derm
4. Eczema
5. PRP
6. Sezary syndrome
7. Drugs
^^^^^Alternatuive erythroderma (REDMAN)
HLA typing
B22—Fixed drug eruption
B27—AS, Reiter’s, Crohn’s, IBD, guttate psoriasis
B51—Behcet’s
B54—Sweet’s
CW6—Psoriasis
D7 -- familial LP
DR1—Crohn’s, p. foliaceus, LP
DR4—DM I, RA
DR6-- Italians with Hep C leading to LP
DQW2—DH, Celiac sprue
DW35—GA
DQ3- EM minor
Lupus symptoms (4+)
Malar rash
Discoid rash
Sun sensitivity
Oral ulcers
Arthritis
Pleuritis/pericarditis
Blood abnormalities
Renal disease (proteinuria/casts)
ANA
Immunologic dz
Neuro dz (Sz/psychosis)
Pigmented purpuras
1. Schamberg's purpura
2. Majocchi's purpura (described as purpura
annularis telangiectoides)
3. Lichen aureus (characterized by a solitary
golden-colored patch with purpura)
4. Gougerot-Blum purpura (typically presenting
as lichenoid papules with purpura on lower
extremities)
5. Eczematid-like purpura of Doucas and
Kapetanakis (characterized by itching and
orange-colored pigmentation).
Radiation
Eczema/psoriasis/PRP
Drugs
Malignancy (MF, sezary, lymphoma)
Autoimmune (dermatomyositis rarely)
No cause (50%)
Moist nodules
Moist-Merkle Cell CA
Bumps-B cell lymphoma
Like-Large cell acanthoma
PG &
Poroma
Harm-Hidradenoma
Skin-syringocystadenoma papilliferum
Tender Nodules
Blue rubber bleb nevus
Leiomyoma
Eccrine Spiradenoma
Neuroma
Dirkams-Adiposa delorosum
Angiolipoma
Neurolemmoma (schwanoma)
Endometrioma
Glomus tumor
Granular cell tumor
Osteoma cutis
Balanitis Circinata
Tinea
Reiter’s
LP
Carpal Tunnel DDx
Scleromyxedema
LISTS
11
6. Wilson’s dz
Papulosquamous Differential
1. Psoriasis
2. Parapsoriasis
3. PLEVA
4. PRP
5. PR
6. LP
7. LE
8. LSC
9. Lymphoma
10. Leprosy
11. Tinea
12. Reiters
Pruritus w/o rash
DM, Drugs
Uremia
Malignancy (Hodgkin’s)
PBC, Polyc. vera, HyperPTH, Pregnancy
Liver dz
Fe deficiency (microcytic anemia)
Thyroid (esp. hypo)
STD (HIV, Hep C)
^^^^ alternative pruritus list DR ITCHING
Drugs, DM, dermatomyositis
Renal disease
Idiopathic
Thyroid dz (hypo>hyper) hyperparathyroid
Cancer including hematologic, anemia, polycythemia
Hepatic dz, HIV
Infestations (scabies etc)
Neurotic
Gestation (pruritus of pregnancy)
Great Imitators
1. Syphilis
2. Leprosy
3. HIV
4. Sarcoidosis
5. Drug
6. MF
7. Factitial Dermatitis
Light Spectrum
Rabbits-radiowaves
Mate-microwaves
In-infrared
Very-visible light
Unusual-UV
Expensive-Xray
Gardens-Gamma
Diseases that can be followed with labs "Lupo's Sassy Siphon Pummels Wagons
Duhring Relapsing Rocky Mountain Showers"
Lupus -- anti-dsDNA (renal involvement)
Sarcoid -- ACE levels
Syphilis -- RPR
Pemphigus -- indirect immuno titers
Wegener's -- cANCA
Dermatitis herpetiformis (Duhring's disease) -anti-endomysial antibodies
Relapsing polychondritis - anti-type II collagen
Rocky Mountain Spotted Fever - platelet levels
SCLE - Ro antibody (Weedon says not true)
Posterior Cataracts
1. Behcet’s
2. Steroids
Erythema Nodosum causes NODOSUM
NO cause found (60%)
Red lunula
Drug (sulfa, bromides, iodides)
Oral contraceptives
Sarcoidosis
Ulcerative Colitis
Microbiology (strep, TB, deep fungal, yersinia)
"Crimson Covers All Lines and Pits"
CHF
Connective tiss dz
Alopecia areata
Lichen planus
Poisoning CO
Blue lunula
1. 5-FU
2. AZT
3. Busulfan
4. Osteogenesis Imperfecta
5. Argyria
Lofgren Synd. features (sarcoid) LOFGREN
Lymphadenopathy
Ocular Uveitis
Fevers
GR = miGRating arthralgias
EN = erythema nodosum
LISTS
Follicular Occlusion tetrad
Hidradenitis Suppurativa
Dissecting cellulites of the scalp
Acne Congloblata
Pilonidal sinus / cyst
Hair stages
Anagen (active, 85-90%, 3years)
Catagen (involution, 1%, 3 weeks)
Telogen (resting, 10-15%, 3 months)
Angiod streaks APPLE PITS
Acromegaly
PXE (#2)
Pagets (#1)
Lead poisoning
Ehler Danlos
Pituitary problems
Iron deficiency
Trauma
Sickle cell dz (#3)
“Gee Now that Summer is Sizzlin’, I’M Sure
Wanting A PEPSI”
IgG: NXG, Scleredema, Scleromyxedema
IgM: Schitzler’s, Waldenstrom’s
IgA: Pyoderma gangrenosum, EED, POEMS,
Sweet’s, Sneddon-Wilkonson, IgA Pemphigus
12