Chapter 9: Stereochemistry

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Chapter 9: Stereochemistry
Things to know:

What are enantiomers? What is a chiral molecule? You should be able to identify
all the chiral centers in a given molecular structure.

What is optical activity? What kinds of compounds exhibit optical activity? What
does levorotatory (-) and dextrorotatory (+) mean? What can you say about the
optical rotation of a pair of enantiomers?

You should be able to assign R and S configuration for each chiral center. Also,
given that a chiral center is R or S, you should be able to draw a structure to
represent this.

What are diasteromers? What is the minimum requirement for a compound to
exist as diastereomers? (it should have at least two chiral centers). You should be
able to decide whether a pair of compounds are enantiomers or diastereomers.
Also, given the structure of a molecule, you should be able to draw its enantiomer
and diastereomers.

What are meso compounds? What are racemic mixtures? What can you say about
the optical activity of meso compounds and racemic mixtures?

Why does the reaction of 1-butene with HBr result in a racemic mixture?

What is prochirality? Know how to determine the Re or Si face of a prochiral
compound.
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