MATERIAL SAFETY DATA SHEET
Section 1.
Product and Company Information
Product Name:
Chloro-Cyanocinnamic Acid (ClCCA)
Catalog Numbers: CMS-109-50mg
Company:
CMS-109-100 mg
Protea Biosciences, Inc.
955 Hartman Run Road
Morgantown, WV 26507 USA
UN Number:
NA
Harmonized Code: 2916390000
Revision Date:
12/14/09
Section 2.
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P: 304.292.2226 ● F: 304.292.7101
www.proteabio.com
Composition / Information on Components
Chemical Characterization: white solid
Description: substances below
Alternative names: (2E)-2-cyano-3-(4-chlorophenyl)-2-Propenoic acid
CAS #
Chemical Name
Percent
20374-46-3
4-chloro-α-cyanocinnamic acid
100%
Section 3.
Hazards Identification
EMERGENCY OVERVIEW
Appearance: white solid
Caution! May cause eye, respiratory system, and skin irritation.
Ingestion: Maybe harmful if swallowed.
Inhalation: Maybe harmful if inhaled. Causes respiratory tract irritation.
Chronic: Low hazard for usual industrial handling.
Information pertaining to particular dangers for man and environment not applicable
Classification system
The classification was made according to the latest editions of the EU-lists.
NFPA ratings (scale 0 to 4)
Health = 2
Fire = 0
Reactivity = 0
Section 4.
First Aid Measures
General Information: No special measures required.
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid.
Skin: Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and
water.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Treat symptomatically and supportively.
Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 5.
Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH
(approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with
air. Combustion generates toxic fumes.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Flash Point: Not available.
Section 6.
Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8. Avoid dust formation and
breathing dust. Ensure adequate ventilation.
Spills/Leaks: A vacuum or sweep up material and place into a suitable disposal container. Clean up spills
immediately, observing precautions in the Protective Equipment section. Do not allow to enter sewers, surface, or
ground water.
Section 7.
Handling and Storage
Handling: No special measures required. Avoid contact with eyes, skin, and clothing. Avoid the formation of dust.
Keep container tightly closed.
Storage: Store at room temperature in a dry, well ventilated place.
Section 8.
Exposure Control / Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a
safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits: Contains no substance with occupational exposure limit values.
OSHA Vacated PELs: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use
a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or
other symptoms are experienced.
Section 9.
Physical and Chemical Properties
Physical State: solid
Appearance: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Flash Point: Not available
Boiling Point: Not available.
Melting Point: Not available.
Decomposition Temperature: Not available.
Water Solubility: Not available
Specific Gravity/Density: Not available.
Molecular Formula: C10H6CINO2
Molecular Weight: 207.6 g/mol
Section 10.
Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Thermal decomposition / conditions to be avoided: Incompatible materials, dust generation, excess heat.
Dangerous reactions: Strong oxidizing agents and strong bases.
Hazardous Decomposition Products: Strong decomposition products formed under fire conditions—carbon
oxides, nitrogen oxides.
Hazardous Polymerization: Will not occur.
Section 11.
Toxicological Information
LD50 Oral Rat – No data available
Teratogenicity: No data available.
LD50 Inhalation Rat – No data available
Reproductive Effects: No data available.
Carcinogenicity: No data available
Mutagenicity: No data available.
Epidemiology: No data available.
Neurotoxicity: No data available.
Section 12.
Ecological Information
Ecotoxicity: No information available.
Environmental: No information available.
Physical: No information available.
Section 13.
Disposal Considerations
Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all
federal, state, and local environmental regulations.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14.
Transport Information
DOT Regulations:
Hazard Class: non-hazardous – This substance is considered to be non-hazardous for transport.
Land transport ADR/RID (cross border):
ADR/RID Class: - No data available
Maritime transport IMDG:
IMDG Class: - No data available
Marine Pollutant: No data available
Air transport ICAO-TI and IATA-DGR:
ICAO/IATA Class: non-hazardous -- This substance is considered to be non-hazardous for air transport.
Transport / Additional information: Not dangerous according to the above specifications.
Section 15.
Regulatory Information
US Federal
TSCA: listed not listed on the TSCA Inventory
SARA Reportable Quantities (RQ): None of the components are on this list
CERCLA/SARA Section 313 Components: No data available
OSHA: No data available
US State
State Right to Know
Indication of Danger: Irritant.
Risk Statements: Irritating to eyes, respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable gloves and eye/face protection.
European/International Regulations
Canada Ingredient Disclosure List
WHMIS Classification: This product has been classified in accordance with the hazard criteria of the CPR,
and the MSDS contains all the information required by the CPR.
DSL: No
NDSL: No
Section 16.
Other Information
MSDS Creation Date: 12.14.09
The information above is believed to be accurate and represents the best information currently available to us.
However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such
information, and we assume no liability resulting from its use. Users should make their own investigations to
determine the suitability of the information for their particular purposes. In no event shall Protea Biosciences be liable
for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental,
consequential or exemplary damages, howsoever arising, even if Protea Biosciences has been advised of the
possibility of such damages.