FACTSHEET
Treatments, Antipsychotic Side Effects: Akathisia
What is Akathisia?
Akathisia is a movement disorder frequently
reported in people with schizophrenia and other
psychiatric illnesses. Prevalence has been
estimated at 20-35% and it can have significant
effects on daily functioning. Akathisia is
characterised by increased motor activity,
particularly complex, semi-purposeful repetitive
movements, in addition to subjective ‘inner’
restlessness, tension, irritability or panic. The
exact causes of movement disorders including
akathisia are unknown, but some evidence has
suggested they may be a side effect of some
antipsychotics.
What is the evidence for Akathisia?
Low to moderate quality evidence suggests
akathisia is reported by people taking both firstand second-generation antipsychotics, although
it is more commonly seen in people taking firstgeneration antipsychotics.
Further information
See technical table
March 2014