Fall 2011 – Organic chemistry – 1 Lab – Chem 353
Instructor: Mahesh Pattabiraman
Office Location: Harlan Hall 216, Phone: 575-538-6641
Email: pattabiramanm@wnmu.edu e-mail is the best way to contact me. Please use your mustang
express account for e-mailing me. I will e-mail messages and important announcements to the class using
Mustang Express, so it is important that you check your account often.
Book: Introduction to Organic Laboratory Techniques by Pavia, Lampman, Kriz, and Engell – 4th edition
Timing: Wednesdays 3 pm - 5 pm
Refer to organic lab syllabus for other information
Instructions:
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Protective eyewear should be used at all times in the lab
Clothing appropriate to lab environment should be worn (including closed toe shoes)
Read experiments before coming to the lab
Pre-lab is due each week before lab begins and it is worth 10 points
Pre-lab should carry Aim, Principle, and Experimental steps. It should serve as a quick
reference for you while performing experiments.
Post-labs need to be submitted the week after before the next lab starts and is worth 20 points
Post-labs should carry the exact details regarding the way experiments were performed,
observations and inferences made. It should also discuss mechanistic details of reactions and
percentage yields for all chemical/physical processes carried in the lab. Finally a short
conclusion outlining what you learnt in the lab and
Order
of
experiments
Experiment
Aug 24th
Experiments # 3A and 3B
i) Crystallization of sulfanilamide using Erlenmayer flask and Hrisch funnel
ii) Craig tube
Experiments # 4 B, 4 C, and 4E
i) Distribution of solute between two immiscible solvents
ii) How to determine which one is the organic layer
iii) Critical thinking application
Experiments # 6A
i) Simple and fractional distillation
Aug 31st
Sep 7th
Sep 14th
Sep 21st
Experiments # 11 and 14A
i) Extraction of oil of cloves
ii) Thin layer chromatography
Experiment # 5C
i)
Monitoring a reaction with thin-layer chromatography
Sep 28th
Oct 5th
Oct 12th
Oct 19th
Oct 26th
Nov 2nd
Experiment # 5D
i)
Column chromatography
ii)
Gas chromatography (GC-MS)
**********Mid-term exam**********
Experiment # 20
i)
Reactivities of some alkyl halides
Experiment 21A and 21 B
i)
Competitive nucleophiles with 1-butanol or 2-butanol
ii)
Competitive nucleophiles with 2-methyl-2-propanol
Experiment # 24 A
i)
Dehydration of 1-butanol and 2-butanol
Experiment # 23 A and B
i)
Synthesis of n-butyl bromide
ii)
Synthesis of n-butyl bromide in semimicroscale
Experiment # 26
i)
Phase-transfer catalysis
Nov 9th
Experiment # 19 B Computational chemistry [ subject to change]
i)
Heats of Reaction: SN1 reaction rates
Nov 16th
Experiment # 18 C and 18D Computational chemistry [ subject to change]
i)
cis and trans-2-butene
Dec 7th
Experiment # 27
i)
Relative reactivities of several aromatic compounds
Final week
*******Final exam************