I.V. ADMINISTRATION GUIDELINES
All IV meds must be administered by IV pump
Medication
Acetadote
Patients greater
than 40 kg
Loading Dose:
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Please use
the Online
calculator:
http://aceta
dote.net/do
secalc.php
150
mg/kg
NO
D5W
Dose 2:
50 mg/kg
Dose 3:
200mL
60 min
500ml
4hr
1000ml
16hr
100mg/kg
Acetadote
Patients greater
than 20 and
less than 40 kg
Loading Dose:
Dose 2:
Dose 3:
Acetadote
Patients less
than 20 kg
Loading Dose:
NO
D5W
50 mg/kg
100ml
60 min
250ml
4hr
500ml
16hr
100mg/kg
Please use
the Online
calculator:
http://aceta
dote.net/do
secalc.php
150
mg/kg
Category
NOTE: WT
BASED DOSING
FOR PATIENTS
USE ICON ON
YOUR
COMPUTER
*
http://acetadote.net/
dosecalc.php
Patients greater
than 40 kg
NOTE: WT
BASED DOSING
FOR PATIENTS
USE ICON ON
YOUR
COMPUTER
Please use
the Online
calculator:
http://aceta
dote.net/do
secalc.php
150
mg/kg
Remarks
NO
D5W
3 mL/kg
of body
weight
60 min
http://acetadote.net/
dosecalc.php
Patients greater
than 20 and less
than 40 kg
NOTE: WT
BASED DOSING
FOR PATIENTS
USE ICON ON
YOUR
COMPUTER
4hr
50 mg/kg
7 mL/kg
of body
weight
http://acetadote.net/
dosecalc.php
16hr
100mg/kg
14 mL/kg
of body
weight
Patients less
than 20 kg
Dose 2:
Dose 3:
*
*
Adenocard
--
1-2
seconds
--
--
--
*
Albumin
12.5 GM
NO
Premixed
50 ml
30 min
RN
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
Category
Aminophylline
250 mg
500 mg
1000 mg
See
remarks
D5W or
NS
50 ml
100 ml
500 ml
15-30
30-60
60
Push -Only for IV
persantine reversal
RN/LPN
Ampicillin
(Omnipen)
1 gm
2 gm
NO
NO
D5W or
NS
50 ml
100 ml
15-20
15-20
Use reconstituted
solution within 1 hr.
RN/LPN
Ativan
--
2 mg/min
NS
--
--
Dilute to 1:1
concentration
Atropine
1 mg
10 ml
over 1-2
min.
--
--
--
Avelox
(nonformulary.
Info only)
400 mg
NO
Premixed
250 ml
60 min
Caution with cardiac
patients.
0.8% saline solution
RN/LPN
Azactam
(Aztreonam)
1 gm
2 gm
3-5 min.
“
D5W or
NS
50 ml
100 ml
20-60
“
Reconstitute with 610 ml SWI
RN/LPN
Bactrim
(Septra)
5 ml
10 ml
NO
NO
D5W
"
125 ml
250 ml
60-90
"
Do not refrigerate
Bretylium
10 ml
Over 1
min.
--
--
--
May be used push
into rapidly flowing IV
*
Bumex
1 mg.
2 min.
--
--
--
--
RN
Calcium
Gluconate
10 ml
2 ml/min.
--
--
--
--
RN
Calcium
Chloride
10 ml
0.5-1
ml/min.
--
--
--
--
RN
Cardizem
(Diltizem)
Cipro
*
*
RN/LPN
----------FOLLOW PROTOCOL----------
*
200 mg
400 mg
NO
NO
D5W or
NS
100 ml
200 ml
60
"
RN/LPN
(Clindamycin)
600 mg
1200 mg
NO
NO
D5W or
NS
50 ml
100 ml
20
40
RN/LPN
Compazine
10 mg.
2 mg/min.
--
--
--
Cleocin
Rapid inj. may cause
hypotension
RN
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
Category
Cordarone
1000mg
NO
100ml
D5W
Standard
IV bags
150 mg
(fast
loading
dose)
10 min
add 3ml (150 mg) to
100ml of D5W
*
you should
still refer to
the package
insert/PDR
500ml
D5W
Aviva IV
Bags
add 18 ml (900 mg)
to 500ml of D5W
the conc. is 1.8mg/ml
------------
------------
360 mg
(slow
loading
dose)
6 hours
to deliver 1mg/min
run at 33cc/hr
540 mg
(maintenance
dose)
18 hours
to deliver 0.5mg/min
run at 17cc/hr
must use
filter
tubing
Decadron
--
1-5 min.
D5W
50 ml
15-20
min.
--
RN
Demerol
25 mg.
3-5 min.
NS
--
--
Dilute (10mg/ml)
Doses greater than
25 mg must be by *
RN
D5W or
NS
At least
50 ml
60min
Depacon
(Depakote IV)
Do not exceed 20
mg/min
Oral and Inj are
interchangeable on a
mg-for-mg basis
RN
Dextrose
amp
3 ml/min.
--
--
--
RN
Diflucan
200 mg
400 mg
NO
Premixed
100 ml
200 ml
60 min
120 min
RN/LPN
Digoxin
(Lanoxin)
--
Over at
least 5 min.
--
--
--
Dilantin
(Phenytoin)
100 mg
Do not
exceed
25-50
mg/min.
NS
ONLY
50 ml
Dilantin
1000 mg
NO
NS
ONLY
250 ml
See attached guidelines
*
20-60
20-60
LOADING
DOSE
Dilaudid
1-2 mg
YES
--
--
2-3 min
Dobutamine
(Dobutrex)
500 mg
NO
Premixed
250 ml
--
Dopamine
800 mg
NO
Premixed
500ml
Titrated
Flush each inj. with NS.
Use filter (0.22 micron)
with dilution.
RN
Flush each inj. with NS.
Use filter (0.22 micron)
with dilution.
RN
RN
--
*
*
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Doxycycline
(Vibramycin)
100 mg
200 mg
NO
NO
D5W or
NS
100 ml
200 ml
60
"
Droperidol
(Inapsine)
1.25 mg
5 min
Edecrin
50 mg.
--
D5W or
NS
--
20 min.
Remarks
Category
RN/LPN
Doses greater than
1.25 mg are restricted
to Anes.
RN
Dilute to 1mg/1ml
RN
Please use 1 ml of
ephedrine (50mg/ml)
and further dilute with
9ml NS for final
5 mg/ml
concentration
Administer 1 ml for a
5 mg dose
*
Ephedrine
5 MG
1 min
NS
9 ml
--
Epinephrine
1:10,000
YES
--
--
--
Caution: available
also in 1:1000
Erythromycin
500 mg
1 gm
NO
NO
NS
"
100 ml
200 ml
20-60
"
Reconstitute with 10cc
preservative free SWI;
then add to NS
Fentanyl
--
--
--
--
--
--
Anes.
Only
Flagyl
500 mg
NO
Premixed
100 ml
60 min.
Store at room temp.
RN/LPN
Folic acid
1 mg
1 min
D5W or
NS
50 ml
15 -30
min
Fortaz
1 gm
10 ml
over 3-5
20 ml
over 3-5
D5W or
NS
"
50 ml
15-30
"
"
NO
D5W or
NS
50 ml
100 ml
30-60
30-60
Should not be mixed
with other drugs
250 ml
minimum
2 hours
once daily dosing
RN
RN/LPN
(Metronidazole)
(Ceftazidime)
2 gm
0-50 mg
50-100 mg
Gentamicin
3-7 mg/kg
Haldol
1-5 mg
NO
D5W
50 ml
15 min
Heparin
25,000 U
YES
Premixed
500 ml
--
LPN/RN
RN/LPN
must be on a cardiac
monitor
May cause changes in
ECG and QTc interval
Titrated
RN/LPN
*
RN/LPN
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
Category
NEW Sliding Scale Insulin Protocol
Blood Glucose (mg/dL)
Dose of Novolog (units)
0–60
0
61–150
151–200
201–250
251–300
301–350
351–400
>400
Insulin Drip
Additional Action
Unconscious-amp D50
Conscious-snack
0
2
4
6
8
10
12
* If patient is symptomatic CALL MD
100 units
NO
Integrilin
NS
100 ml
No action
No action
No action
No action
No action
No action
Call MD
FOLLOW PROTOCOL
--FOLLOW PROTOCOL--
Isuprel
1 mg
--
D5W
250 ml
--
Invanz
1 gm
NO
NS
50 ml
30
RN
*
*
Reconstitute with 10
ml of SWI or NS
RN/LPN
Do not mix or coinfuse with other
medications
Do not use Diluents
containing Dextrose
Kefzol
(Ancef)
Labetalol
(Normadyne,
Trandate)
Lasix
(Furosemide)
New one
Levaquin
2 gm
10 ml over
3-5 min
20 ml over
3-5 min
D5W or
NS
"
20 mg
2 min
D5W or
NS
100 mg
20
mg/min
1 gm
500 mg
750 mg
NO
50 ml
15-30
100 ml
30-60
160 ml
2 ml/min
D5W or
NS
100ml
Rate
ordered
by
physician
PREMIX
PREMIX
100 ml
150 ml
60
90
RN/LPN
TO PREPARE DRIP:
Add 40 ml Labetalol to
160 ml of diluent. The
resultant solution will
contain 1 mg/ml
As a drip the rate
should not exceed
4mg/min.
Please remove 10 ml
from a 100 ml bag. Add
100 mg (10 ml) of lasix
for a resultant conc.
of 1 mg/ml
100ml/hr
100ml/hr
RN
RN
RN/LPN
Medication
Dose
Push
(min.)
Diluent
Levophed
4mg
NO
D5W
Librium
100 mg.
3 min.
NS
--
--
Lidocaine
0.4%
25-50
mg/min
Bolus rate
Premixed
500ml
Per
orders
Lipids
20%
NO
Premixe
d
250 ml
Lopressor
5 mg.
3-5 min.
--
--
NO
Premixed
3-5
--
Magnesium
Mannitol
1 gram
50 ml
Amount
250ml or
1000ml
100 ml
--
Over
(min.)
Protocol
Remarks
Category
Follow the protocol
dilute with 5ml
*
*
Over at
least 5
hours
Use special tubing
RN
--
--
*
30 min
--
RN
Do not use if crystals
have formed
RN
Use a filter
Maxipime
(cefipime)
0-2gm
NO
D5W or
NS
50 ml
30
RN/LPN
Mefoxin
(Cefoxitin)
1 gm
2 gm
10 ml
over 3-5
D5W or
NS
50 ml
“
15-20
“
RN/LPN
Morphine
4 mg.
4-5 min.
--
--
--
Morphine
Drip
Morphine
PCA
RN
Use a 30mg/30 ml
Morphine PCA
NO
NO
--
--
30mg/30 ml
Must use PCA
set in
constant
infusion mode
Doses greater than
4 mg must be by*
conc of 1mg/1ml
RN
Dose/Rate determined
by physician
1mg/ml
Ex: 1mg/hr
MVI
Nafcillin
Narcan
(Naloxone)
amp
NO
--
500 ml
as
directed
0 – 1 Gm
NO
NS
50 ml
30
Over 1 gm
NO
100 ml
60
0.4 mg
15 sec.
--
--
RN/LPN
Natrecor
Nitroglycerin
RN/LPN
--
Often more than one
dose is necessary in
overdose
--FOLLOW PROTOCOL-50 mg
NO
Premixed
250 ml
Titrate
RN
*
Do not use filters.
Medication
Dose
Push
(min.)
NO
Diluent
D5W
Amount
250 ml
Over
(min.)
Titrate
Remarks
Category
Use glass bottles
only.
*
Protect from light.
Reconstitute with 2-3
ml Dextrose
*
Nitroprusside
(Nipride)
--
OFIRMEV IV
1000 mg
NO
Premixed
100ml
15 min
RN
10-40
units
NO
D5W or
NS
1000 ml
As
ordered
RN
0-5 million
5-10 million
NO
NO
D5W
"
50 ml
100 ml
15-30
"
RN/LPN
Acetaminophen
IV
Oxytocin
Penicillin
Central
line only
Phenergan
25 mg.
--
--
--
Must dilute with 10-20
ml normal saline
before administering
IV
3-5 min.
Phenylephrine
Potassium
Chloride
Potassium
Phosphate
50 mcg
10 mEq
1 min
NO
Protonix
(Intermittent
Drip)
Premixed
1 - 5 ml
6 - 10 ml
Procainamide
(Pronestyl)
NS
99 ml
100 ml
--
one hour
(100 ml/hr)
NO
IVP is only for patients
with central line
access
250 ml
4 hours
D5W or
NS
500 ml
8 hours
Loading
dose
--
D5W
100 ml
60
Maint. dose
--
D5W
500 ml
24 hours
40 mg
--
NS
100 ml
15 min
Please place 1 ml of
phenylephrine
(10mg/ml) in 99 ml
NS for a final conc of
100 mcg/ml.
Administer 0.5ml for a
50 mcg dose
May be given at higher
concentrations and rates in
emergencies
RN
*
AliquotsRN
Check with MD for prn
lidocaine for patient
comfort
DOSE= 10-30 MG
DilutedRN/LPN
NOTE: Each ml
provides:
+
4.4mEq K
3mM Phos
RN
Follow protocol
*
To prepare a 40mg/100
ml NS solution, remove
10 ml NS from the bag
and use it to
reconstitute the vial.
Add the contents of the
vial back into the bag to
RN
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
Category
have a conc. of 40
mg/100ml or 0.4 mg/ml
Protonix IV should not
be used if the pt can
take the oral form
Protonix
(Bolus)
40 mg
2 min
Protonix should be
reconstituted with 10ml
0.9% NS
RN
Protonix IV should not
be used if the pt can
take the oral form
Protonix
(Continuous
Drip)
8mg/hr
--
NS
ONLY
250 ml
25 ml/hr
delivers 8
mg/hr
Rally Pack
Is
outsourced
Thiamine
100 mg
Folic acid
1 mg
NS
MVI
1000ml
10 hours
1 amp
Mag sulfate
2 grams
Reglan
10 mg
To prepare a 80mg/250
NS solution, remove
20 ml of NS from the
bag and use 10 ml to
reconstitute the first 40
mg vial and the other 10
ml to reconstitute the
second vial. Add the
contents of both vials
back into the bag to
have a conc. of
80mg/250 ml NS
solution or
0.32 mg/ml
Please contact
Pharmacy Services
Inc. to prepare it for
us. They are the
same company that
makes our TPN.
Please just fax a copy
of the orders just like
TPN.
RN
RN
fax 546-7409
Ph. # 800-326-9975
1-2
Retavase
D5W
50 ml
20 min.
RN
--FOLLOW PROTOCOL--
*
Robaxin
(Methocarbamol)
10 ml
4-5 min
--
--
--
Administer while in
recumbent position.
Maintain position 15-30
minutes following
injection
Robinul
--
--
--
--
--
--
Rocephin
1 gm
2 gm
10 ml
over 3-5
D5W
"
50 ml
"
15-30
"
RN
Anes.
only
RN/LPN
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
Category
Romazicon
2 ml
O.R.- 15 sec.
Overdosage 30 sec.
--
--
--
--
*
Sandostatin
100 mcg
3 min
D5W or
NS
100 ml
15-30
Sodium
Bicarb.
Amp.
Rapidly
D5W or
NS
--
--
1-5 min.
1-5 min.
D5W
"
50 ml
100 ml
30 min.
"
1 min.
5 min.
D5W
"
50 ml
"
30-60
"
Solu-cortef
0-50 mg
(Hydrocortisone)
50-100 mg
Solu-medrol
10-40 mg
100-250
mg
(Methyprednisolone)
Streptokinase
*
--
RN/LPN
For a 125 mg/2ml vial
20 mg = 0.32ml
40 mg = 0.64 ml
60 mg = 0.96 ml
80 mg = 1.28 ml
100 mg = 1.60 ml
120 mg = 1.92 ml
---FOLLOW PROTOCOL---
–
Tagamet
300 mg
20 ml over
1-2 min.
D5W
50 ml
15-20
Thiamine
100 mg
NO
D5W or
NS
50 -100
ml
15 -30
min
Timentin
3.1 gm
--
D5W or
NS
50 ml
30 min.
NO
D5W or
NS
50 ml
100 ml
30-60
30-60
Should not be mixed
with other drugs
250 ml
minimum
2 hours
once daily dosing
--
--
--
–
0-50 mg
50-100 mg
Tobramycin
Toradol
TPA
3-7 mg/kg
30 mg
1-3 min.
--
–
–
---FOLLOW PROTOCOL---
RN/LPN
*
Synthroid
Oral
Conversions
–
RN
25 mcg = 0.025 mg
50 mcg = 0.050 mg
75 mcg = 0.075 mg
100 mcg = 0.1 mg
200 mcg = 0.2 mg
RN/LPN
RN/LPN
May not be
given push
LPN/RN
RN/LPN
RN/LPN
RN
*
Medication
Dose
Push
(min.)
Unasyn
(Ampicillin/
Sulbactam)
0 - 1.5 Gm
NO
Over 1.5 gm
NO
Diluent
Amount
Over
(min.)
Remarks
Category
50 ml
30
NOT ON
FORMULARY
RN/LPN
100 ml
30
NS
Use reconstituted
solution within 1 hr.
Valium
(Diazepam)
--
5
mg/min.
--
--
--
Flush with NS
before/after
*
Vancomycin
500 mg
1 gm
NO
NO
D5W or
NS
100 ml
200-250 ml
30-60
min.
"
May cause
hypotension. Slow rate
to stop flushing Rxn.
RN/LPN
Mix 10 ml of SWI into
a 1 gm vial and the
resultant solution will
be 100 mg/ml.
Vancomycin
IV for ORAL
use
This is how to
mix
Vancomycin
IV for ORAL
use
ANY
ORAL
DOSE
ORAL
USE
ONLY
SWI
(Sterile
Water for
Inj.)
250mg =.2.5 ml
500 mg = 5 ml
RN/LPN
Maybe further diluted
with water for ORAL
administration
Refrigerate after
reconstituting
Vasopressin
40 IU
--
--
--
--
Vasotec
2.5mg
5 min
D5W or
NS
50 ml
15-20
min
RN
VENOFER
(Iron Sucrose)
100 mg
2-5 min
NS
100 ml
15 min
RN
5 mg/2 ml
2 min.
--
--
--
*
--FOLLOW PROTOCOL--
*
Verapamil
(Calan)
Versed
infusion
Vitamin K
1-10 mg
NO
D5W or
NS
50 ml
30 min
one time dose
Only for INR >20 or
active bleeding
must be on a cardiac
monitor in ER or CCU
***Warning regarding IV use:
Severe rxn's including death
have occurred during and
immediately after IV injection
even when precautions have
*
Physician
*
or
under
direct
supervision of
the
Medication
Dose
Push
(min.)
Diluent
Amount
Over
(min.)
Remarks
been taken to dilute the
vitamin and avoid rapid
infusion. IV route should be
restricted to those situations
where other routes are not
feasible and the serious risk
involved is considered
justified
Zantac
50 mg
--
Premixed
100 ml
30 min.
Zinacef
750 mg
D5W
50 ml
15-20
1.5 gm
10 ml over
3-5
20 ml over
3-5
"
100 ml
"
500mg
NO
D5W or
NS
250cc
Zithromax
Category
physician
who must
be present
RN/LPN
Dilute 750 mg vial
with 8 ml SWI
RN/LPN
1 hour
This is a 2mg/ml conc.
RN/LPN
500cc
3 hours
This is a 1mg/ml conc.
Failure has to have been
proved with prior agents
before Zofran can be
administered.
Zofran
4 MG
2-5
--
--
--
NO
D5W or
NS
50-150
ml
30 min.
Zosyn
2.25 gm
3.375 gm
Zyvox
600 mg
NO
premixed
300 ml
30 - 120
Reconstitute
10 ml/SWI
15 ml/SWI
Not compaible with
any other meds
RN
RN/LPN
RN/LPN
Use for only
documented MRSA
and VRE
 THIS IS ONLY A PARTIAL LIST OF IV MEDS THAT MAY BE USED AT THIS INSTITUTION.
 These are guidelines and the dose is to the discretion of the physician.
 Digoxin IV may be given to digitalized patients for maintenance therapy without mandatory cardiac monitoring (per Pharmacy &
Therapeutics minutes)
* = ACLS RN, CCU RN, ER RN, CRNA, NURSING SUPERVISOR AUG 2012