Martindale: The Complete Drug Reference

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Martindale: The Complete Drug Reference
Paracetamol
Date of monograph review: 31-Jul-1997; 13-Jul-1998; 21-Mar-2000; 09-Nov-2001; 29Jul-2003; 18-Jun-2004; 05-Oct-2004; 31-May-2006; 13-Feb-2007; 10-Sep-2008; 12Feb-2010; 20-Aug-2010; 05-Aug-2011; (latest modification: 05-Dec-2011)
Drug Nomenclature (Latest modification: 05-Dec-2011)
Synonyms: παρακεταμόλη; Acetaminofeno; Acetaminophen; N-Acetyl-p-aminophenol;
Asetaminofen; Paracétamol; Paracetamolis; Paracetamolo; Paracetamolum;
Parasetamol; Parasetamoli; ‫ ;ب ارا س ي تامول‬アセトアミノフェン; ‫ ;פרצטמול‬对乙酰氨基酚
BAN: Paracetamol
INN: Paracetamol [rINN (en)]
INN: Paracetamol [rINN (es)]
INN: Paracétamol [rINN (fr)]
INN: Paracetamolum [rINN (la)]
INN: Парацетамол [rINN (ru)]
INN: ‫[ ب ارا س ي تامول‬rINN (ar)]
INN: 对乙酰氨基酚 [rINN (cn)]
Chemical name: 4′-Hydroxyacetanilide; N-(4-Hydroxyphenyl)acetamide
Molecular formula: C8H9NO2 =151.2
CAS: 103-90-2
ATC code: N02BE01
ATC code (veterinary): QN02BE01
UNII code: 362O9ITL9D
Chemical Structure of Paracetamol
NOTE:
Compounded preparations of paracetamol may be represented by the following names:
Co-bucafAPAP (PEN)—butalbital, paracetamol, and caffeine
Martindale: The Complete Drug Reference
Co-codamol x/y (BAN)—where x and y are the strengths in milligrams of codeine
phosphate and paracetamol respectively
Co-codAPAP (PEN)—paracetamol and codeine phosphate
Co-dydramol (BAN)—dihydrocodeine tartrate 1 part and paracetamol 50 parts
(w/w)
Co-hycodAPAP (PEN)—hydrocodone tartrate and paracetamol
Co-methiamol x/y (BAN)—where x and y are the strengths in milligrams of
DL-
methionine and paracetamol, respectively
Co-oxycodAPAP (PEN)—oxycodone and paracetamol
Co-proxamol (BAN)—dextropropoxyphene hydrochloride 1 part and paracetamol
10 parts (w/w)
Co-proxAPAP (PEN)—dextropropoxyphene napsilate and paracetamol
Pharmacopoeias:
In Chin., Eur. (see
), Int., Jpn, US, and Viet.
Ph. Eur. 7 (Paracetamol). A white or almost white, crystalline powder. Sparingly soluble
in water; freely soluble in alcohol; very slightly soluble in dichloromethane. Protect from
light.
USP 35 (Acetaminophen). A white odourless crystalline powder. Soluble 1 in 20 of
boiling water, 1 in 10 of alcohol, and 1 in 15 of 1N sodium hydroxide. Store in airtight
containers. Protect from light. Protect from moisture and heat.
Adverse Effects and Treatment (Latest modification: 13-Aug-2011)
Adverse effects of paracetamol are rare and usually mild, although haematological
reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and
agranulocytosis have been reported. Rashes and other hypersensitivity reactions occur
occasionally.
Martindale: The Complete Drug Reference
Injection site reactions such as pain and a burning sensation are common after
parenteral use; hypotension and tachycardia have been reported rarely. Application site
reactions have also been noted after rectal use.
Overdosage with paracetamol can result in severe liver damage and sometimes acute
renal tubular necrosis. Prompt treatment with acetylcysteine or methionine is essential
and is discussed under Overdosage,
.
(last reviewed 2011-08-05; last modified 2011-08-13)
References.
(last reviewed 2011-08-05; last modified 2006-12-07)
1. 1. Graham GG, et al. Tolerability of paracetamol. Drug Safety 2005; 28: 227–40.
PubMed
Carcinogenicity (Latest modification: 30-Jun-2011)
A prospective cohort study1 involving over 64 000 men and women between 50 and 76
years of age found that use of paracetamol for more than 4 days a week for longer than
4 years was associated with a twofold increase in the risk of haematological
malignancies. The authors considered that other prospective studies were required
before any recommendations about paracetamol use could be made.
(last reviewed 2011-08-05; last modified 2011-06-30)
1. 1. Walter RB, et al. Long-term use of acetaminophen, aspirin, and other nonsteroidal
anti-inflammatory drugs and risk of hematologic malignancies: results from the
prospective vitamins and lifestyle (VITAL) study. J Clin Oncol 2011; 29: 2424–31.
PubMed
Effects on the cardiovascular system (Latest modification: 16-Jun-2011)
Large cohort studies1,2 have shown an association between the use of non-opioid
analgesics, including paracetamol, and a significantly increased risk of hypertension in
women; similar studies3,4 in men have been equivocal but suggest a more moderate
increase in risk. However, it has also been suggested5 that the hypertension may have
Martindale: The Complete Drug Reference
been caused by pain itself or more likely to be detected in patients taking more
paracetamol due to a higher frequency of visits to their doctor.
(last reviewed 2011-08-05; last modified 2011-06-16)
1. 1. Dedier J, et al. Nonnarcotic analgesic use and the risk of hypertension in US women.
Hypertension 2002; 40: 604–8. PubMed
2. 2. Forman JP, et al. Non-narcotic analgesic dose and risk of incident hypertension in US
women. Hypertension 2005; 46: 500–507. PubMed
3. 3. Kurth T, et al. Analgesic use and risk of subsequent hypertension in apparently
healthy men. Arch Intern Med 2005; 165: 1903–9. PubMed
4. 4. Forman JP, et al. Frequency of analgesic use and risk of hypertension among men.
Arch Intern Med 2007; 167: 394–9. PubMed
5. 5. Montgomery B. Does paracetamol cause hypertension? BMJ 2008; 336: 1190–1.
PubMed
Effects on the ears (Latest modification: 30-Jun-2011)
A questionnaire study in nearly 27 000 male health professionals originally aged 40
years and over has examined the association between hearing loss and the regular use
of aspirin, NSAIDs, and paracetamol.1 During 369 079 person-years of follow-up, 3488
cases of hearing loss were reported; regular analgesic use (defined as 2 or more times a
week) was found to be independently associated with an increased risk of hearing loss
for all 3 types of analgesics. The hazard ratio of hearing loss for regular users of
paracetamol was 1.22 when compared with those who used analgesics less frequently;
the risk also increased with longer duration of use. Concomitant use of more than one
type of analgesic also had an additive risk effect.
For reference to reports of hearing loss associated with the abuse or overuse of
preparations containing paracetamol, see under Dextropropoxyphene,
Hydrocodone,
, and
.
(last reviewed 2011-08-05; last modified 2011-06-30)
1. 1. Curhan SG, et al. Analgesic use and the risk of hearing loss in men. Am J Med 2010;
123: 231–7. PubMed
Effects on the kidneys (Latest modification: 21-Mar-2004)
Martindale: The Complete Drug Reference
For reference to evidence that abuse or prolonged excessive use of analgesics, including
paracetamol, can produce nephropathy, see under NSAIDs,
See also under Overdosage,
.
.
(last reviewed 2011-08-05; last modified 2004-03-21)
Effects on metabolism (Latest modification: 25-Jan-2010)
Use of paracetamol, alone or with other drugs (see under Flucloxacillin,
), has been
associated with accumulation of pyroglutamic acid, resulting in pyroglutamic aciduria (5oxoprolinuria) and high-anion gap metabolic acidosis.1-3
(last reviewed 2011-08-05; last modified 2010-01-25)
1. 1. Humphreys BD, et al. Acetaminophen-induced anion gap metabolic acidosis and 5oxoprolinuria (pyroglutamic aciduria) acquired in hospital. Am J Kidney Dis 2005; 46:
143–6. PubMed
2. 2. Fenves AZ, et al. Increased anion gap metabolic acidosis as a result of 5-oxoproline
(pyroglutamic acid): a role for acetaminophen. Clin J Am Soc Nephrol 2006; 1: 441–7.
PubMed
3. 3. Alados Arboledas FJ, et al. Acidosis piroglutámica asociada a paracetamol. An Pediatr
(Barc) 2007; 67: 582–4. PubMed
Effects on the respiratory tract (Latest modification: 24-Nov-2011)
The results of a case-control study1 have suggested that the frequent (daily or weekly)
use of paracetamol may be associated with asthma. However, the UK CSM has
commented that the results of this study do not alter any advice regarding the use of
paracetamol and that it remains a safe and effective pain killer for many patients
including asthmatics.
Subsequently, others have found an increase in the prevalence of asthma2,3 and COPD2
with frequent (daily or weekly) use of paracetamol. A link between paracetamol use in
pregnancy and asthma in children has also been suggested (see Pregnancy under
Precautions,
). However, one review4 stated that there have been very few actual
reports of paracetamol causing asthma; furthermore, bronchospasm is not a recognised
Martindale: The Complete Drug Reference
feature of paracetamol overdosage. This review concluded that a strong link between
paracetamol use and asthma was unlikely.
More recently, analysis of questionnaire data5 for 205 487 children aged 6 to 7 years
from 31 countries suggested that the use of paracetamol in the first year of life and later
childhood was associated with an increased risk of asthma and also symptoms of
rhinoconjunctivitis and eczema. In another questionnaire study6 by the same group
involving 322 959 adolescents aged 13 to 14 years from 50 countries, the recent use of
paracetamol was also found to increase the risk of asthma, rhinoconjunctivitis, and
eczema. However, after considering the first study, the UK CHM7 expressed concerns
over data interpretation and concluded that it did not provide strong evidence that
paracetamol use in infancy can cause asthma; the CHM reiterated that paracetamol
remains a safe and appropriate analgesic for children. Furthermore, a small cohort
study8 has also found that, although the use of paracetamol in the first 2 years of life
increased the crude risk of asthma in children aged 6 to 7 years, this increase was not
noted after adjustment for early respiratory-tract infections or when paracetamol use
was limited to non-respiratory-tract infections.
(last reviewed 2011-08-05; last modified 2011-11-24)
1. 1. Shaheen SO, et al. Frequent paracetamol use and asthma in adults. Thorax 2000;
55: 266–70. PubMed
2. 2. McKeever TM, et al. The association of acetaminophen, aspirin, and ibuprofen with
respiratory disease and lung function. Am J Respir Crit Care Med 2005; 171: 966–71.
PubMed
3. 3. Eneli I, et al. Acetaminophen and the risk of asthma: the epidemiologic and
pathophysiologic evidence. Chest 2005; 127: 604–12. PubMed
4. 4. Nuttall SL, et al. Does paracetamol cause asthma? J Clin Pharm Ther 2003; 28: 251–
7. PubMed
5. 5. Beasley R, et al. ISAAC Phase Three Study Group. Association between paracetamol
use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in
children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet
2008; 372: 1039–48. PubMed
6. 6. Beasley RW, et al. ISAAC Phase Three Study Group. Acetaminophen use and risk of
asthma, rhinoconjunctivitis, and eczema in adolescents: International Study of Asthma
and Allergies in Childhood Phase Three. Am J Respir Crit Care Med 2011; 183: 171–8.
PubMed
Martindale: The Complete Drug Reference
7. 7. MHRA/CHM. Paracetamol use in infancy: no strong evidence for asthma link. Drug
Safety Update 2008; 2 (4): 9. Available at: online (accessed 13/10/09)
8. 8. Lowe AJ, et al. Paracetamol use in early life and asthma: prospective birth cohort
study. Abridged version: BMJ 2010; 341: 713. PubMed Full version: online (accessed
06/05/11)
Hypersensitivity (Latest modification: 10-Sep-2008)
Reactions characterised by urticaria, dyspnoea, and hypotension have occurred after use
of paracetamol in adults1-4 and children.5,6 Angioedema has also been reported.7 Fixed
drug eruptions, confirmed by rechallenge, have been described,8-11 and toxic epidermal
necrolysis has occurred.12
(last reviewed 2011-08-05; last modified 2008-09-10)
1. 1. Stricker BHC, et al. Acute hypersensitivity reactions to paracetamol. BMJ 1985; 291:
938–9. PubMed
2. 2. Van Diem L, Grilliat JP. Anaphylactic shock induced by paracetamol. Eur J Clin
Pharmacol 1990; 38: 389–90. PubMed
3. 3. Kumar RK, Byard I. Paracetamol as a cause of anaphylaxis. Hosp Med 1999; 60: 66–
7. PubMed
4. 4. Bachmeyer C, et al. Acetaminophen (paracetamol)-induced anaphylactic shock.
South Med J 2002; 95: 759–60. PubMed
5. 5. Ellis M, et al. Immediate adverse reactions to acetaminophen in children: evaluation
of histamine release and spirometry. J Pediatr 1989; 114: 654–6. PubMed
6. 6. Bousetta K, et al. Hypersensitivity reactions to paracetamol in children: a study of 25
cases. Allergy 2005; 60: 1174–7. PubMed
7. 7. Idoko JA, et al. Angioneurotic oedema following ingestion of paracetamol. Trans R
Soc Trop Med Hyg 1986; 80: 175. PubMed
8. 8. Thomas RHM, Munro DD. Fixed drug eruption due to paracetamol. Br J Dermatol
1986; 115: 357–9. PubMed
9. 9. Cohen HA, et al. Fixed drug eruption caused by acetaminophen. Ann Pharmacother
1992; 26: 1596–7. PubMed
10.10. Harris A, Burge SM. Vasculitis in a fixed drug eruption due to paracetamol. Br J
Dermatol 1995; 133: 790–1. PubMed
11.11. Hern S, et al. Bullous fixed drug eruption due to paracetamol with an unusual
immunofluorescence pattern. Br J Dermatol 1998; 139: 1129–31. PubMed
12.12. Halevi A, et al. Toxic epidermal necrolysis associated with acetaminophen ingestion.
Ann Pharmacother 2000; 34: 32–4. PubMed
Martindale: The Complete Drug Reference
Overdosage (Latest modification: 24-Nov-2011)
Acute oral overdosage with paracetamol, whether accidental or deliberate, is relatively
common and can be extremely serious because of the narrow margin between
therapeutic and toxic doses. Adults taking as little as 10 to 15 g of paracetamol within
24 hours may develop severe hepatocellular necrosis and, less often, renal tubular
necrosis. Paracetamol-induced hepatotoxicity is a major cause of acute liver failure in
western countries. Patients should be considered at risk of severe liver damage if they
have ingested more than 150 mg/kg of paracetamol or 12 g or more in total, whichever
is the smaller. The risk of severe toxicity after acute paracetamol overdose appears to
be less in children than in adults at comparable doses; however, chronic use of
supratherapeutic doses in children has resulted in unintentional overdoses and severe
hepatotoxicity.1,2
Patients receiving enzyme-inducing drugs or those with a history of alcohol abuse are at
high risk of hepatic damage, as may be patients suffering from malnutrition such as
those with anorexia, AIDS, or cystic fibrosis. Those who have not eaten for a few days or
those with a low body-weight3 are also predisposed to hepatotoxicity. Such high-risk
patients may develop hepatotoxicity with as little as 75 mg/kg of paracetamol
(equivalent to about 5 g in a patient who weighs 70 kg) ingested within 24 hours.
Early signs of overdosage (very commonly nausea and vomiting although they may also
include lethargy and sweating) usually settle within 24 hours. Abdominal pain may be
the first indication of liver damage, which is not usually apparent for 24 to 48 hours and
sometimes may be delayed for up to 4 to 6 days after ingestion. Liver damage is
generally at a maximum 72 to 96 hours after ingestion. Hepatic failure, encephalopathy,
coma, and death may result. Complications of hepatic failure include acidosis, cerebral
oedema, haemorrhage, hypoglycaemia, hypotension, infection, and renal failure.
Prothrombin time increases with deteriorating liver function and some recommend that it
be measured regularly. However, as both paracetamol4 and acetylcysteine5 can
independently affect prothrombin time in the absence of hepatic injury, the use of
prothrombin time as a marker for hepatotoxicity has been questioned and it has been
recommended that treatment decisions are based on the entire liver biochemistry.6
Martindale: The Complete Drug Reference
Acute renal failure with acute tubular necrosis may develop, even in the absence of
severe liver damage. Other non-hepatic symptoms that have been reported following
paracetamol overdosage include myocardial abnormalities and pancreatitis.
The mechanism of toxicity in overdosage with paracetamol is thought to be the
production of a minor but highly reactive metabolite, N-acetyl-p-benzoquinoneimine
(NABQI) by cytochrome P450 isoenzymes (mainly CYP2E1 and CYP3A4)2 in the liver and
kidney. The amount of NABQI produced after normal doses of paracetamol is usually
completely detoxified by conjugation with glutathione and excreted as mercaptopurine
and cysteine conjugates. In paracetamol overdosage, tissue stores of glutathione
become depleted, allowing NABQI to accumulate and bind to sulfhydryl groups within
hepatocytes causing cell damage. Substances capable of replenishing depleted stores of
glutathione, such as acetylcysteine or methionine, are therefore used as antidotes in
paracetamol overdosage. Acetylcysteine may also be involved in the repair of damaged
tissue.
Treatment of oral paracetamol overdosage. The management of paracetamol
overdosage as practised in the UK and USA has been the subject of many reviews.6-15
Guidelines have also been issued in the UK by the Paracetamol Information Centre.16
Separate consensus guidelines have been issued by clinical toxicologists in Australia and
New Zealand.17
Prompt treatment is essential, even when there are no obvious symptoms, and all
patients should be admitted to hospital; full supportive measures should also be
instituted.
Activated charcoal may be used to reduce gastrointestinal absorption, if it can be
given within 1 hour of the overdose, and if more than 150 mg/kg or 12 g of
paracetamol (whichever is smaller) has been ingested. However, if acetylcysteine or
methionine is to be given orally the charcoal is best cleared from the stomach to
prevent it reducing the absorption of the antidote.
There is little evidence that gastric lavage is of benefit in those who have overdosed
solely with paracetamol.
The plasma-paracetamol concentration should be determined as soon as possible,
but not within 4 hours of ingestion, to ensure that peak concentrations are recorded.
Martindale: The Complete Drug Reference
The risk of liver damage is determined by comparison with a nomogram reference
line on a plot of plasma-paracetamol concentration against hours after ingestion. A
semi-logarithmic plot or a linear plot may be used. Generally, antidote treatment is
required if the patient's plasma-paracetamol concentration is higher than the
appropriate line (but see below).
Patients receiving enzyme-inducing drugs such as carbamazepine, phenytoin,
phenobarbital, rifampicin, and St John's wort, those with malnutrition or a history of
alcohol abuse, or those who have not eaten for a few days are considered at high
risk, and should receive an antidote if their plasma-paracetamol concentrations are
up to 50% below the standard reference line. Similar patients at risk include those
with eating disorders or AIDS and children with cystic fibrosis or those who have
failed to thrive.
Plasma-paracetamol concentrations measured more than 15 hours after ingestion
are not reliable indicators of hepatotoxicity. Furthermore, the nomogram may not be
suitable for use when patients have taken modified-release preparations of
paracetamol.18-20 Some suggestions for modified strategies for the use of the
Rumack-Matthew nomogram in the face of overdosage with modified-release
preparations have been made.21-23
Plasma-paracetamol concentrations and the Rumack-Matthew nomogram are also of
little value in patients who have taken repeated supratherapeutic doses or multiple
overdoses of paracetamol over a short period of time: such patients should be
considered at serious risk and given antidote treatment.
Deaths from liver failure have occurred in patients presenting with plasmaparacetamol concentrations below the treatment line: suggested explanations
include inadequate patient histories and a need for a lower treatment threshold.24
If there is any doubt about timing or the need to treat, then a patient should be
treated with an antidote. In some centres, patients who have ingested 150 mg/kg or
more of paracetamol are treated regardless of plasma-paracetamol concentrations.25
Antidote treatment should be started as soon as possible after suspected
paracetamol ingestion and should not be delayed while awaiting the results of
plasma assays. Once the results become available, treatment may be stopped if the
Martindale: The Complete Drug Reference
initial concentration was below the nomogram reference line. However, if the initial
concentration is above the reference line, the full course of antidote must be given
and should not be stopped when subsequent plasma concentrations fall below the
reference line.
Choice of antidote. Acetylcysteine (
) is usually the antidote of choice but the route of
administration varies, and the best protocol has yet to be determined.6,26 Intravenous
use has been associated with anaphylactic reactions but is the preferred route in some
countries including Australia, New Zealand, and the UK because of fears that oral
absorption might be reduced by vomiting or activated charcoal. However, in the USA the
oral route is also licensed, and is clearly effective. The use of methionine (
) orally is
licensed in the UK, despite the same risks of impaired absorption due to vomiting or
activated charcoal. It is cheaper and easier to give than intravenous acetylcysteine and
may be used in situations where a patient cannot be transferred to hospital, provided it
is given within 10 to 12 hours of the overdose and the patient is not vomiting.
Acetylcysteine is most effective when given during the first 8 hours after taking the
overdose and the effect diminishes progressively thereafter. It used to be believed that
starting treatment more than 15 hours after overdosage was of no benefit and might
aggravate the risk of hepatic encephalopathy. However, late treatment was
subsequently shown to be safe,27 and studies of patients treated up to 36 hours after
ingestion suggest that benefit may be obtained up to and possibly beyond 24 hours.28,29
Furthermore, giving intravenous acetylcysteine to patients who had already developed
fulminant hepatic failure has been shown to reduce morbidity and mortality.30
An initial dose of 150 mg/kg (maximum of 16.5 g) of acetylcysteine in 200 mL of
glucose 5% is given intravenously over 15 minutes in the UK, or over 60 minutes in
the USA. This is followed by an intravenous infusion of 50 mg/kg (maximum of
5.5 g) in 500 mL of glucose 5% over the next 4 hours and then 100 mg/kg
(maximum of 11 g) in one litre over the next 16 hours. Sodium chloride 0.9% may
be used where glucose 5% is unsuitable. The volume of intravenous fluids should be
modified for children or those with a body-weight of less than 40 kg. If an
anaphylactoid reaction develops, the infusion should be stopped and an
antihistamine given; it may be possible to continue the acetylcysteine infusion at a
slower rate.
Martindale: The Complete Drug Reference
In the USA, acetylcysteine may also be given orally as an alternative to parenteral
treatment. It is given as an initial dose of 140 mg/kg as a 5% solution followed by
70 mg/kg every 4 hours for an additional 17 doses. Some31 have suggested
increasing the loading dose of oral acetylcysteine when it is given after activated
charcoal, whereas others32 have found that the efficacy of acetylcysteine is not
reduced by use of activated charcoal beforehand and consider a larger acetylcysteine
dose unnecessary.
Methionine, like acetylcysteine, is most effective when given as early as possible after
paracetamol overdosage. However, it is not as effective if treatment is delayed33-35 and
hepatic damage is more frequent and severe if treatment with methionine is started
more than 10 hours after ingestion; it may also precipitate hepatic encephalopathy.
The usual oral dose of methionine in adults and children aged over 6 years is 2.5 g
every 4 hours for 4 doses starting less than 10 to 12 hours after ingestion of the
paracetamol and provided the patient is not vomiting. Children aged under 6 years
should be given 1 g every 4 hours for 4 doses.
The literature relating to the use of methionine in paracetamol poisoning is, in general,
imprecise as to the form of methionine used. Preparations containing both methionine
and paracetamol (co-methiamol) have been formulated for use in situations where
overdosage may occur.
Histamine H2-antagonists. It has been suggested that since cimetidine blocks the hepatic
cytochrome P450 mixed function oxidase system, it might be of use as an adjunct to
acetylcysteine for patients whose production of the toxic metabolite of paracetamol is
increased due to enzyme induction. Although there have been several anecdotal reports
claiming benefit for cimetidine in patients with paracetamol poisoning, there is no
current evidence to support these claims.6,10,12,36
Liver transplantation may be considered as a last recourse in some patients.
After maternal overdosage during pregnancy fetal metabolism of paracetamol that
crosses the placenta can produce sufficient hepatotoxic metabolites to cause fetal
hepatotoxicity. Limited data from case reports and a case series suggest that early
treatment with oral or intravenous acetylcysteine can be safe and effective in such
Martindale: The Complete Drug Reference
cases;37 the UK National Teratology Information Service recommends the use of
acetylcysteine if clinically indicated.
Dosage errors with intravenous paracetamol have been reported, particularly in young
children; rarely, such errors have resulted in substantial overdoses and liver damage.38
The standard nomogram may not be appropriate in determining treatment from plasmaparacetamol concentrations after overdosage by intravenous infusion, as it is based on
data from acute paracetamol ingestion rather than intravenous administration. Plasmaparacetamol concentrations more than 4 hours after intravenous injection are usually
lower than those predicted for the same oral dose at the same time-point after
ingestion. Furthermore, patients receiving intravenous paracetamol are likely to have an
increased risk of hepatotoxicity due to poor nutrition from acute fasting. The UK National
Poisons Information Service recommends antidote treatment with intravenous
acetylcysteine (see above for doses) when 60 mg/kg or more of paracetamol in total has
been given intravenously to adults and children within 24 hours. If there is uncertainty
about the actual dose of paracetamol given, the standard nomogram may be used to
determine the risk of liver damage. Antidote treatment (see above) is required if
plasma-paracetamol concentrations, measured at least 4 hours after administration, are
up to 50% below the reference line for high-risk patients (for example—treat if the
concentration is above 50 mg/L at 4 hours).
(last reviewed 2011-08-05; last modified 2011-11-24)
1. 1. Miles FK, et al. Accidental paracetamol overdosing and fulminant hepatic failure in
children. Med J Aust 1999; 171: 472–5. PubMed
2. 2. American Academy of Pediatrics Committee on Drugs. Acetaminophen toxicity in
children. Pediatrics 2001; 108: 1020–4. PubMed
3. 3. Claridge LC, et al. Acute liver failure after administration of paracetamol at the
maximum recommended daily dose in adults. BMJ 2010; 341: 1269–70. PubMed
4. 4. Whyte IM, et al. Acetaminophen causes an increased International Normalized Ratio
by reducing functional factor VII. Ther Drug Monit 2000; 22: 742–8. PubMed
5. 5. Schmidt LE, et al. Effect of acetylcysteine on prothrombin index in paracetamol
poisoning without hepatocellular injury. Lancet 2002; 360: 1151–2. PubMed
6. 6. Brok J et al. Interventions for paracetamol (acetaminophen) overdoses. Available in
The Cochrane Database of Systematic Reviews; Issue 2. Chichester: John Wiley; 2006
(accessed 23/10/06). PubMed
Martindale: The Complete Drug Reference
7. 7. Whitcomb DC, et al. Association of acetaminophen hepatotoxicity with fasting and
ethanol use. JAMA 1994; 272: 1845–50. PubMed
8. 8. Makin AJ, et al. Management of severe cases of paracetamol overdosage. Br J Hosp
Med 1994; 52: 210–13. PubMed
9. 9. Vale JA, Proudfoot AT. Paracetamol (acetaminophen) poisoning. Lancet 1995; 346:
547–52. PubMed
10.10. Prescott LF. Paracetamol overdose. In: Paracetamol (acetaminophen): a critical
bibliographic review. London: Taylor & Francis, 1996: 401–73.
11.11. Routledge P, et al. Paracetamol (acetaminophen) poisoning. BMJ 1998; 317: 1609–
10. PubMed
12.12. Zed PJ, Krenzelok EP. Treatment of acetaminophen overdose. Am J Health-Syst
Pharm 1999; 56: 1081–91. PubMed
13.13. Kozer E, Koren G. Management of paracetamol overdose: current controversies.
Drug Safety 2001; 24: 503–12. PubMed
14.14. Dart RC, et al. Acetaminophen poisoning: an evidence-based consensus guideline
for out-of-hospital management. Clin Toxicol 2006; 44: 1–18. PubMed
15.15. Ferner RE, et al. Management of paracetamol poisoning. BMJ 2011; 342: d2218.
PubMed
16.16. Paracetamol Information Centre. Guidelines for the management of acute
paracetamol overdosage (revised 2007). Also available at: online (accessed 23/7/8)
17.17. Daly FFS, et al. Panel of Australian and New Zealand clinical toxicologists.
Guidelines for the management of paracetamol poisoning in Australia and New
Zealand—explanation and elaboration: a consensus statement from clinical toxicologists
consulting to the Australasian poisons information centres. Med J Aust 2008; 188: 296–
301. PubMed Also available at: online (accessed 13/08/08)
18.18. Graudins A, et al. Overdose of extended-release acetaminophen. N Engl J Med
1995; 333: 196. PubMed
19.19. Vassallo S, et al. Use of the Rumack-Matthew nomogram in cases of extendedrelease acetaminophen toxicity. Ann Intern Med 1996; 125: 940. PubMed
20.20. Dart RC, et al. The safety profile of sustained release paracetamol during
therapeutic use and following overdose. Drug Safety 2005; 28: 1045–56. PubMed
21.21. Temple AR, Mrazik TJ. More on extended-release acetaminophen. N Engl J Med
1995; 333: 1508. PubMed
22.22. Graudins A, et al. More on extended-release acetaminophen. N Engl J Med 1995;
333: 1508–9. PubMed
23.23. Cetaruk EW, et al. Extended-release acetaminophen overdose. JAMA 1996; 275:
686. PubMed
Martindale: The Complete Drug Reference
24.24. Bridger S, et al. Deaths from low dose paracetamol poisoning. BMJ 1998; 316:
1724–5. PubMed
25.25. Aujla KS, et al. Nomogram does not show absolute concentration for treatment. BMJ
1998; 317: 1655. PubMed
26.26. Kanter MZ. Comparison of oral and i.v. acetylcysteine in the treatment of
acetaminophen poisoning. Am J Health-Syst Pharm 2006; 63: 1821–7. PubMed
27.27. Parker D, et al. Safety of late acetylcysteine treatment in paracetamol poisoning.
Hum Exp Toxicol 1990; 9: 25–7. PubMed
28.28. Smilkstein MJ, et al. Efficacy of oral N-acetylcysteine in the treatment of
acetaminophen overdose: analysis of the National Multicenter Study (1976 to 1985). N
Engl J Med 1988; 319: 1557–62. PubMed
29.29. Harrison PM, et al. Improved outcome of paracetamol-induced fulminant hepatic
failure by late administration of acetylcysteine. Lancet 1990; 335: 1572–3. PubMed
30.30. Keays R, et al. Intravenous acetylcysteine in paracetamol induced fulminant hepatic
failure: a prospective controlled trial. BMJ 1991; 303: 1026–9. PubMed
31.31. Chamberlain JM, et al. Use of activated charcoal in a simulated poisoning with
acetaminophen: a new loading dose for N-acetylcysteine? Ann Emerg Med 1993; 22:
1398–1402. PubMed
32.32. Spiller HA, et al. A prospective evaluation of the effect of activated charcoal before
oral N-acetylcysteine in acetaminophen overdose. Ann Emerg Med 1994; 23: 519–23.
PubMed
33.33. Vale JA, et al. Intravenous N-acetylcysteine: the treatment of choice in paracetamol
poisoning? BMJ 1979; 2: 1435–6. PubMed
34.34. Vale JA, et al. Treatment of acetaminophen poisoning: the use of oral methionine.
Arch Intern Med 1981; 141: 394–6. PubMed
35.35. Tee LGB, et al. N-Acetylcysteine for paracetamol overdose. Lancet 1986; i: 331–2.
PubMed
36.36. Kaufenberg AJ, Shepherd MF. Role of cimetidine in the treatment of acetaminophen
poisoning. Am J Health-Syst Pharm 1998; 55: 1516–19. PubMed
37.37. Wilkes JM, et al. Acetaminophen overdose in pregnancy. South Med J 2005; 98:
1118–22. PubMed
38.38. Beringer RM, et al. Intravenous paracetamol overdose: two case reports and a
change to national treatment guidelines. Arch Dis Child 2011; 96: 307–8. PubMed
Pancreatitis (Latest modification: 07-Dec-2006)
Drug-induced pancreatitis associated with paracetamol was reported1 to be a rare
reaction only occurring in patients taking more than recommended doses. In a
Martindale: The Complete Drug Reference
retrospective study of data from 814 patients who had taken paracetamol overdoses,
hyperamylasaemia was detected in 246, and was more common and more severe in
patients transferred to a specialist unit because of more severe poisoning.2 However,
acute pancreatitis was diagnosed only in 33 cases.
(last reviewed 2011-08-05; last modified 2006-12-07)
1. 1. Underwood TW, Frye CB. Drug-induced pancreatitis. Clin Pharm 1993; 12: 440–8.
PubMed
2. 2. Schmidt LE, Dalhoff K. Hyperamylasaemia and acute pancreatitis in paracetamol
poisoning. Aliment Pharmacol Ther 2004; 20: 173–9. PubMed
Precautions (Latest modification: 08-Jun-2011)
Paracetamol should be given with care to patients with impaired kidney or liver function;
the BNF 61 recommends that large doses should be avoided in patients with hepatic
impairment. It should also be given with care to patients with alcohol dependence,
chronic malnutrition, or dehydration.
(last reviewed 2011-08-05; last modified 2011-06-08)
Breast feeding (Latest modification: 08-Jun-2011)
No adverse effects have been seen in breast-fed infants whose mothers were receiving
paracetamol, and the last available guidance from the American Academy of Pediatrics
considered1 that it is therefore usually compatible with breast feeding. The BNF 61 also
considers that the amount of paracetamol distributed into breast milk is too small to be
harmful to a breast-fed infant.
Pharmacokinetic studies in 12 nursing mothers given a single dose of paracetamol
showed that peak paracetamol concentrations in breast milk of 10 to 15 micrograms/mL
were achieved in 1 to 2 hours. Plasma concentrations were determined in 2 mothers; a
breast milk to plasma ratio of about 1 was reported.2 Similar findings have been
reported from other studies.3,4
(last reviewed 2011-08-05; last modified 2011-06-08)
Martindale: The Complete Drug Reference
1. 1. American Academy of Pediatrics. The transfer of drugs and other chemicals into
human milk. Pediatrics 2001; 108: 776–89. PubMed [Retired May 2010] Correction.
ibid.; 1029. Also available at: online (accessed 19/10/06)
2. 2. Berlin CM, et al. Disposition of acetaminophen in milk, saliva, and plasma of lactating
women. Pediatr Pharmacol 1980; 1: 135–41. PubMed
3. 3. Hurden EL, et al. Excretion of paracetamol in human breast milk. Arch Dis Child
1980; 55: 969–72.
4. 4. Bitzén P-O, et al. Excretion of paracetamol in human breast milk. Eur J Clin
Pharmacol 1981; 20: 123–5. PubMed
Hepatic impairment (Latest modification: 02-Jan-2011)
Reviews1,2 have concluded that there is evidence that paracetamol could be and had
been used safely in patients with liver disease. Studies had also shown that although the
half-life of paracetamol was prolonged in such patients, glutathione concentrations in
those taking recommended doses were not depleted to the critical levels that would
enable accumulation of paracetamol's hepatotoxic metabolite.
(last reviewed 2011-08-05; last modified 2011-01-02)
1. 1. Benson GD, et al. The therapeutic use of acetaminophen in patients with liver
disease. Am J Ther 2005; 12: 133–41. PubMed
2. 2. Chandok N, Watt KDS. Pain management in the cirrhotic patient: the clinical
challenge. Mayo Clin Proc 2010; 85: 451–8. PubMed
Porphyria (Latest modification: 07-Nov-2011)
The Drug Database for Acute Porphyria, compiled by the Norwegian Porphyria Centre
(NAPOS) and the Porphyria Centre Sweden, classifies paracetamol as probably not
porphyrinogenic; it may be used as a drug of first choice and no precautions are
needed.1
(last reviewed 2011-08-05; last modified 2011-11-07)
1. 1. The Drug Database for Acute Porphyria. Available at: online (accessed 11/10/11)
Pregnancy (Latest modification: 24-Nov-2011)
Martindale: The Complete Drug Reference
The UK National Teratology Information Service recommends that paracetamol may be
used in pregnancy if appropriate. As a whole, animal and epidemiological studies show
that the therapeutic use of paracetamol during pregnancy does not increase the risk of
an adverse outcome.1
A large prospective study has reported that the frequent use of paracetamol (defined as
most days or daily use) in late pregnancy (20 to 32 weeks of gestation) may be
associated with an increased risk of persistent wheezing in the infant2 which may persist
into childhood;3 use during early pregnancy was not associated with an increased risk.
Several reviews and meta-analyses have considered the link between childhood asthma
and wheezing and prenatal paracetamol exposure;4-6 however, while some consider that
there may be a link, others consider that the data were conflicting and evidence for a
causal association is inconclusive (see also Effects on the Respiratory Tract,
).
Furthermore, the authors of the original study2 emphasised that the number of pregnant
women taking frequent doses was very small and they recommended that infrequent
paracetamol should remain the analgesic of choice in pregnancy.
For reference to a possible association between simple analgesics including paracetamol
and congenital cryptorchidism, see under NSAIDs,
.
(last reviewed 2011-08-05; last modified 2011-11-24)
1. 1. Scialli AR, et al. A review of the literature on the effects of acetaminophen on
pregnancy outcome. Reprod Toxicol 2010; 30: 495–507. PubMed
2. 2. Shaheen SO, et al. Paracetamol use in pregnancy and wheezing in early childhood.
Thorax 2002; 57: 958–63. PubMed
3. 3. Shaheen SO, et al. Prenatal paracetamol exposure and risk of asthma and elevated
immunoglobulin E in childhood. Clin Exp Allergy 2005; 35: 18–25. PubMed
4. 4. Scialli AR, et al. Childhood asthma and use during pregnancy of acetaminophen: a
critical review. Reprod Toxicol 2010; 30: 508–19. PubMed
5. 5. Etminan M, et al. Acetaminophen use and the risk of asthma in children and adults: a
systematic review and metaanalysis. Chest 2009; 136: 1316–23. PubMed
6. 6. Eyers S, et al. Paracetamol in pregnancy and the risk of wheezing in offspring: a
systematic review and meta-analysis. Clin Exp Allergy 2011; 41: 482–9. PubMed
Renal impairment (Latest modification: 07-Dec-2006)
Martindale: The Complete Drug Reference
Caution is recommended when giving paracetamol to patients with renal impairment.
Plasma concentrations of paracetamol and its glucuronide and sulfate conjugates are
increased in patients with moderate renal failure and in patients on dialysis.1-3 It has
been suggested that paracetamol itself may be regenerated from these metabolites.1,2
There are conflicting data on whether the conjugates of paracetamol accumulate in
patients with renal impairment receiving multiple doses.2,3
(last reviewed 2011-08-05; last modified 2006-12-07)
1. 1. Prescott LF, et al. Paracetamol disposition and metabolite kinetics in patients with
chronic renal failure. Eur J Clin Pharmacol 1989; 36: 291–7. PubMed
2. 2. Martin U, et al. The disposition of paracetamol and the accumulation of its
glucuronide and sulphate conjugates during multiple dosing in patients with chronic
renal failure. Eur J Clin Pharmacol 1991; 41: 43–6. PubMed
3. 3. Martin U, et al. The disposition of paracetamol and its conjugates during multiple
dosing in patients with end-stage renal failure maintained on haemodialysis. Eur J Clin
Pharmacol 1993; 45: 141–5. PubMed
Interactions (Latest modification: 08-Jun-2011)
The risk of paracetamol toxicity may be increased in patients receiving other potentially
hepatotoxic drugs or drugs that induce liver microsomal enzymes. The absorption of
paracetamol may be accelerated by drugs such as metoclopramide. Excretion may be
affected and plasma concentrations altered when given with probenecid. Colestyramine
reduces the absorption of paracetamol if given within 1 hour of paracetamol.
(last reviewed 2011-08-05; last modified 2011-06-08)
Reviews.
(last reviewed 2011-08-05; last modified 2007-01-30)
1. 1. Toes MJ, et al. Drug interactions with paracetamol. Am J Ther 2005; 12: 56–66.
PubMed
Antibacterials (Latest modification: 08-Sep-2010)
The plasma-paracetamol concentrations considered an indication for antidote treatment
(see Overdosage,
) should be halved in patients receiving enzyme-inducing drugs
Martindale: The Complete Drug Reference
such as rifampicin. Severe hepatotoxicity at therapeutic doses or moderate overdoses of
paracetamol has been reported in patients receiving isoniazid, alone1-3 or with other
drugs for tuberculosis.4
For the effects of paracetamol on chloramphenicol, see
.
For reports of metabolic effects when paracetamol is given with flucloxacillin, see under
Adverse Effects and Precautions of Flucloxacillin,
.
(last reviewed 2011-08-05; last modified 2010-09-08)
1. 1. Murphy R, et al. Severe acetaminophen toxicity in a patient receiving isoniazid. Ann
Intern Med 1990; 113: 799–800. PubMed
2. 2. Moulding TS, et al. Acetaminophen, isoniazid, and hepatic toxicity. Ann Intern Med
1991; 114: 431. PubMed
3. 3. Crippin JS. Acetaminophen hepatotoxicity: potentiation by isoniazid. Am J
Gastroenterol 1993; 88: 590–2. PubMed
4. 4. Nolan CM, et al. Hepatotoxicity associated with acetaminophen usage in patients
receiving multiple drug therapy for tuberculosis. Chest 1994; 105: 408–11. PubMed
Anticoagulants (Latest modification: 15-Mar-1999)
For the effects of paracetamol on oral anticoagulants, see under Warfarin,
.
(last reviewed 2011-08-05; last modified 1999-03-15)
Antiepileptics (Latest modification: 08-Sep-2010)
The plasma-paracetamol concentrations considered an indication for antidote treatment
(see Overdosage,
) should be halved in patients receiving enzyme-inducing drugs
such as carbamazepine, phenobarbital, phenytoin, or primidone.
For the effects of paracetamol on lamotrigine, see
.
(last reviewed 2011-08-05; last modified 2010-09-08)
Antivirals (Latest modification: 30-May-2006)
For reports of adverse effects on the liver associated with use of paracetamol with
antiviral drugs, see under Interferon Alfa,
and Zidovudine,
.
Martindale: The Complete Drug Reference
(last reviewed 2011-08-05; last modified 2006-05-30)
Probenecid (Latest modification: 07-Dec-2006)
Pretreatment with probenecid can decrease paracetamol clearance and increase its
plasma half-life.1 Although urinary excretion of the sulfate and glucuronide conjugates of
paracetamol are reduced, that of paracetamol is unchanged.
(last reviewed 2011-08-05; last modified 2006-12-07)
1. 1. Kamali F. The effect of probenecid on paracetamol metabolism and pharmacokinetics.
Eur J Clin Pharmacol 1993; 45: 551–3. PubMed
Pharmacokinetics (Latest modification: 25-Jan-2010)
Paracetamol is readily absorbed from the gastrointestinal tract and peak plasma
concentrations occur about 10 to 60 minutes after oral doses. Paracetamol is distributed
into most body tissues. It crosses the placenta and is present in breast milk. Plasmaprotein binding is negligible at usual therapeutic concentrations but increases with
increasing concentrations. The elimination half-life of paracetamol varies from about 1 to
3 hours.
Paracetamol is metabolised mainly in the liver and excreted in the urine mainly as the
glucuronide and sulfate conjugates. Less than 5% is excreted as unchanged
paracetamol. A minor hydroxylated metabolite (N-acetyl-p-benzoquinoneimine), is
usually produced in very small amounts by cytochrome P450 isoenzymes (mainly
CYP2E1 and CYP3A4) in the liver and kidney. It is usually detoxified by conjugation with
glutathione but may accumulate after paracetamol overdosage and cause tissue
damage.
(last reviewed 2011-08-05; last modified 2010-01-25)
References.
(last reviewed 2011-08-05; last modified 2011-08-13)
1. 1. van der Marel CD, et al. Paracetamol and metabolite pharmacokinetics in infants. Eur
J Clin Pharmacol 2003; 59: 243–51. PubMed
Martindale: The Complete Drug Reference
2. 2. Gregoire N, et al. Safety and pharmacokinetics of paracetamol following intravenous
administration of 5 g during the first 24 h with a 2-g starting dose. Clin Pharmacol Ther
2007; 81: 401–5. PubMed
3. 3. Kumpulainen E, et al. Paracetamol (acetaminophen) penetrates readily into the
cerebrospinal fluid of children after intravenous administration. Pediatrics 2007; 119:
766–71. PubMed
4. 4. Palmer GM, et al. I.V. acetaminophen pharmacokinetics in neonates after multiple
doses. Br J Anaesth 2008; 101: 523–30. PubMed
5. 5. Liukas A, et al. Pharmacokinetics of intravenous paracetamol in elderly patients. Clin
Pharmacokinet 2011; 50: 121–9. PubMed
Absorption (Latest modification: 07-Dec-2006)
The absorption of paracetamol was slow and incomplete in vegetarian subjects
compared with non-vegetarian subjects.1
(last reviewed 2011-08-05; last modified 2006-12-07)
1. 1. Prescott LF, et al. Impaired absorption of paracetamol in vegetarians. Br J Clin
Pharmacol 1993; 36: 237–40. PubMed
Uses and Administration (Latest modification: 16-Jun-2011)
Paracetamol, a para-aminophenol derivative, has analgesic and antipyretic properties
and weak anti-inflammatory activity. Paracetamol is given orally or as a rectal
suppository for mild to moderate pain (
) and for fever (
). It may also be given by
intravenous infusion for the short-term treatment of moderate pain, particularly after
surgery, and of fever. Paracetamol is often the analgesic or antipyretic of choice,
especially in the elderly and in patients in whom salicylates or other NSAIDs are contraindicated. Such patients include asthmatics, those with a history of peptic ulcer, and
children.
The usual oral dose is 0.5 to 1 g every 4 to 6 hours up to a maximum of 4 g daily.
Paracetamol may also be given as suppositories in a rectal dose of 0.5 to 1 g every 4 to
6 hours, up to 4 times daily.
Paracetamol is given by intravenous infusion over 15 minutes; dosage may be
calculated according to body-weight as follows:
Martindale: The Complete Drug Reference
over 50 kg, single doses of 1 g every 4 or more hours, to a maximum of 4 g daily
from 33 to 50 kg, single doses of 15 mg/kg every 4 or more hours, to a maximum of
60 mg/kg (up to 3 g) daily
A maximum intravenous dose of 3 g daily should also not be exceeded in patients with
chronic alcoholism, chronic malnutrition, or dehydration, regardless of their bodyweight.
For doses in children, or in hepatic or renal impairment, see
,
, and
,
respectively.
(last reviewed 2011-08-05; last modified 2011-06-16)
References.
(last reviewed 2011-08-05; last modified 2010-01-25)
1. 1. Prescott LF. Paracetamol (acetaminophen): a critical bibliographic review. London:
Taylor & Francis, 1996.
2. 2. Bannwarth B, Péhourcq F. Bases pharmacologiques de l'emploi du paracétamol:
aspects pharmacocinétiques et pharmacodynamiques. Drugs 2003; 63 (suppl 2): 5–13.
PubMed
3. 3. Prescott LF. Nouvelles perspectives avec le paracétamol. Drugs 2003; 63 (suppl 2):
51–6. PubMed
4. 4. Duggan ST, Scott LJ. Intravenous paracetamol (acetaminophen). Drugs 2009; 69:
101–13. PubMed
Administration in children (Latest modification: 13-Aug-2011)
In the UK, the licensed oral doses of paracetamol for pain and fever in children, given
according to age, every 4 to 6 hours if necessary up to a maximum of 4 doses in 24
hours, are:
3 months to 1 year: 60 to 120 mg
1 to 5 years: 120 to 250 mg
6 to 12 years: 250 to 500 mg
Martindale: The Complete Drug Reference
The UK MHRA1 has further advised that, within the age range stated above, the following
doses, to be given to a maximum of 4 doses in 24 hours, will replace the current
licensed doses by about the end of 2011:
3 to 6 months: 60 mg
6 months to 2 years: 120 mg
2 to 4 years: 180 mg
4 to 6 years: 240 mg
6 to 8 years: 240 or 250 mg
8 to 10 years: 360 or 375 mg
10 to 12 years: 480 or 500 mg
In younger children the BNFC 2011/12 suggests the following doses:
neonates 28 to 32 weeks postmenstrual age (gestational age at birth plus
chronological age): 20 mg/kg as a single dose then 10 to 15 mg/kg every 8 to 12
hours if necessary up to a maximum of 30 mg/kg daily
neonates over 32 weeks postmenstrual age: 20 mg/kg as a single dose then 10 to
15 mg/kg every 6 to 8 hours if necessary up to a maximum of 60 mg/kg daily
1 to 3 months of age: 30 to 60 mg every 8 hours if necessary
The BNFC 2011/12 also suggests higher oral doses for use in children with severe
postoperative pain:
1 month to 12 years: 20 to 30 mg/kg as a single dose followed by 15 to 20 mg/kg
every 4 to 6 hours if necessary up to a maximum of 90 mg/kg daily. Usual adult
maximum single and daily doses (see
) should not be exceeded
UK licensed rectal doses, which may be given to children every 4 to 6 hours if
necessary, up to 4 times daily are:
3 months to 1 year: 60 to 125 mg
Martindale: The Complete Drug Reference
1 to 5 years: 125 to 250 mg
6 to 12 years: 250 to 500 mg
The BNFC 2011/12 suggests the following rectal doses in younger children:
neonates 28 to 32 weeks postmenstrual age: 20 mg/kg as a single dose then
15 mg/kg every 12 hours if necessary to a maximum of 30 mg/kg daily
neonates over 32 weeks postmenstrual age: 30 mg/kg as a single dose then
20 mg/kg every 8 hours if necessary to a maximum of 60 mg/kg daily
1 to 3 months of age: 30 to 60 mg every 8 hours if necessary
The BNFC 2011/12 also suggests higher rectal doses for use in children with severe
postoperative pain:
1 to 3 months: 30 mg/kg as a single dose followed by 15 to 20 mg/kg every 4 to 6
hours to a maximum of 90 mg/kg daily
older children: 30 to 40 mg/kg as a single dose followed by 15 to 20 mg/kg every 4
to 6 hours to a maximum of 90 mg/kg daily. Usual adult maximum single and daily
doses (see
) should not be exceeded
Doses by intravenous infusion in children, given, according to body-weight, over 15
minutes, are:
full-term neonates and other children below 10 kg: single doses of 7.5 mg/kg every
4 or more hours, to a maximum of 30 mg/kg daily. The BNFC 2011/12 suggests a
dose of 10 mg/kg every 4 to 6 hours to a maximum of 30 mg/kg daily; intravenous
paracetamol has not been studied in premature neonates but the BNFC 2011/12
suggests for premature neonates over 32 weeks postmenstrual age, a dose of
7.5 mg/kg every 8 hours to a maximum of 25 mg/kg daily
between 10 and 33 kg: single doses of 15 mg/kg every 4 or more hours, to a
maximum of 60 mg/kg (up to 2 g) daily
from 33 to 50 kg: single doses of 15 mg/kg every 4 or more hours, to a maximum
of 60 mg/kg (up to 3 g) daily
Martindale: The Complete Drug Reference
over 50 kg: usual adult doses (see
)
The intravenous solution may be diluted to a minimum strength of one-tenth of its
original concentration in sodium chloride 0.9% or glucose 5%; the diluted solution
should be used within 1 hour of preparation.
For post-immunisation pyrexia, an oral or rectal dose of 60 mg has been
recommended for children 2 to 3 months of age. If necessary a second dose may be
given after six hours; if the pyrexia persists after that dose, medical advice should be
sought.
It has been suggested2 that the recommended doses of paracetamol for children may
result in subtherapeutic blood concentrations, and that an initial loading dose should be
given, followed by regular doses up to the recommended maximum daily dose.
However, the appropriate maximum daily dose remains controversial, and there is
obvious concern given the risks of overdosage.
(last reviewed 2011-08-05; last modified 2011-08-13)
1. 1. MHRA. Press release: more exact paracetamol dosing for children to be introduced
(issued 6th June, 2011). Available at: online (accessed 17/06/11)
2. 2. Zacharias M, Watts D. Pain relief in children. BMJ 1998; 316: 1552. PubMed
Administration in hepatic impairment (Latest modification: 13-Aug-2011)
There is evidence to suggest that paracetamol can be safely used in patients with
hepatic impairment (see under Precautions,
); however, reduced doses may be
warranted to avoid accidental overdosages. The BNF 61 recommends avoiding large
doses in patients with hepatic impairment; others have suggested that doses of 2 to 3 g
daily should not be exceeded in patients with cirrhosis requiring long-term use although
a daily dose of 3 to 4 g may be safe for short-term or one-off use.1 UK licensed product
information recommends that the maximum dose of intravenous paracetamol should not
exceed 3 g daily in patients with hepatic impairment or chronic alcoholism; it also states
that those with severe impairment should not be given paracetamol by this route.
(last reviewed 2011-08-05; last modified 2011-08-13)
Martindale: The Complete Drug Reference
1. 1. Chandok N, Watt KDS. Pain management in the cirrhotic patient: the clinical
challenge. Mayo Clin Proc 2010; 85: 451–8. PubMed
Administration in renal impairment (Latest modification: 08-Jun-2011)
In renally impaired patients with a creatinine clearance of 30 mL/minute or less it is
recommended that the interval between each intravenous paracetamol dose is increased
to 6 hours.
(last reviewed 2011-08-05; last modified 2011-06-08)
Headache (Latest modification: 13-Aug-2011)
Non-opioid analgesics such as paracetamol, aspirin, and other NSAIDs are often tried
first for the symptomatic treatment of various types of headache including migraine (see
) and tension-type headache (see
). These drugs given at the onset of symptoms
can successfully treat an acute attack of migraine. However, absorption may be poor
due to gastric stasis which is commonly present in migraine. For this reason dispersible
and effervescent preparations and compound preparations containing drugs such as
metoclopramide which relieve gastric stasis have been advocated.
References.
(last reviewed 2011-08-05; last modified 2011-08-13)
1. 1. Derry S, et al. Paracetamol (acetaminophen) with or without an antiemetic for acute
migraine headaches in adults. Available in The Cochrane Database of Systematic
Reviews; Issue 11. Chichester: John Wiley; 2010 (accessed 03/12/10). PubMed
Pain (Latest modification: 04-Aug-2004)
Paracetamol is used in the management of mild to moderate pain (see Choice of
Analgesic,
). It is of similar potency to aspirin, but with weak anti-inflammatory
activity. Paracetamol may also be used as an adjunct to opioids in the management of
severe pain such as cancer pain (
children (
group (see
). Paracetamol is the preferred choice for pain in
) because of the association of aspirin with Reye's syndrome in this age
). In the treatment of rheumatic disorders, a weak anti-inflammatory
effect limits the role of paracetamol. However, it may be of benefit for simple pain
Martindale: The Complete Drug Reference
control in rheumatoid arthritis (
Spondyloarthropathies,
) and ankylosing spondylitis (see under
), although these patients usually require the additional anti-
inflammatory effects provided by NSAIDs. Synovial inflammation is usually only a minor
component of osteoarthritis (
), and paracetamol is generally recommended as first
choice of treatment before NSAIDs are tried. Paracetamol is useful for the relief of acute
low back pain (
).
Dependence and tolerance are not a problem with non-opioid analgesics such as
paracetamol, but there is a ceiling of efficacy, above which increasing the dose has no
further therapeutic effect.
(last reviewed 2011-08-05; last modified 2004-08-04)
Preparations (Latest modification: 06-Feb-2012)
Single-ingredient Preparations (Latest modification: 06-Feb-2012)
The symbol ¤ denotes a preparation which is discontinued or no longer actively
marketed.
Argentina: Acetolit; Alikal Dolor; Apracur Antifebril¤; Apracur Te Antifebril; Bio Grip-T;
Causalon; Custodial¤; Dirox; Doxidol¤; Dristancito¤; Fiebrolex¤; Fiebrolito¤; Flash;
Guemusin¤; Inmunogrip T Caliente; Invernosan¤; Itedal; Mejoral; Multifebrin¤; Nodipir;
Nodolex¤; Novo Asat; Para Z Mol; Parageniol; Paratral; Parclen; PH 4 Plus¤; Plovacal;
Predualito¤; Qura Plus; Tafirol T; Tafirol; Termofren; Tetradox; Tylenol¤; Vick
Vitapyrena; Viclor; Australia: Asprol¤; Ceetamol¤; Chemists Own Pain & Fever;
Childrens Panadol; Dymadon; Febridol¤; Junior Disprol¤; Kiddy Calm¤; Lemsip
Headcold¤; Lemsip; Ordov Febrigesic¤; Panacete¤; Panadol; Panamax; Parahexal¤;
Paralgin; Parasin¤; Paraspen¤; Parmol¤; Perfalgan; Setamol¤; Tempra¤; Tylenol¤;
Austria: Apacet¤; Becetamol¤; Ben-u-ron; Duaneo; Enelfa¤; Gewamol¤; Grippostad;
Kratofin simplex¤; Mexalen; Momentum; OSA¤; Parakapton¤; Paraspeed¤; Peinfort¤;
Perfalgan; Trimedil; Tylenol¤; Belgium: Algostase Mono; Croix Blanche Mono; Curpol¤;
Dafalgan; Docpara; Dolol-Instant; Dolprone; Efferalgan¤; Lemgrip¤; Lemsip; Lonarid
Mono¤; Neuridon¤; Panadol; Pe-Tam; Perdolan; Perfusalgan; Sanicopyrine; Supadol
Mono¤; Tempra¤; Brazil: Acetamil; Acetamol¤; Acetofen; Anador PRT; Anatyl;
Baicurina¤; Calpol¤; Cefabrina; Cetafrin¤; Cetynol¤; Chalena¤; Contradol¤; Cyfenol;
Dordendril¤; Dorfen¤; Dorfenol; Dorib¤; Dorico; Dorsanol; Dorvan¤; Emsgrip;
Martindale: The Complete Drug Reference
Febralgin¤; Fervex; Gripeonil¤; Gripotermon; Pacemol¤; Paracemil¤; Paracen;
Parador¤; Paralgen; Paratermol¤; Piramin; Pyrimel; Sonridor; Termo-Ped¤; Termol;
Tilekin; Trifen; Tyflen¤; Tylalgin¤; Tylecetamol; Tyleflan¤; Tylenol; Tylephen; Tylidol;
Unigrip; Canada: 222 AF¤; Abenol; Acet; Acetab¤; AF Anacin¤; Alsiphene¤; Anacin-3¤;
Apap; Arthritis Pain; Artritol; Atasol; Benylin DM-D-E-A Cold and Sinus; Cephanol¤;
Childrens Feverhalt; Cold and Flu-in-One; Double Strength Children's Tempra; Fortolin;
Headarest¤; Infant Tempra; Infants Tylenol; Multi-gesic¤; Novo-Gesic; Painaid Free;
Panadol; Pediaphen; Pediatrix; Procet; Rapid Action; Relief; Robigesic¤; Rounox¤;
Taminol; Tantaphen¤; Tempra; Tylenol Arthritis Pain; Tylenol Muscle Aches & Body Pain;
Tylenol; Vicks Custom Care Body Aches; Chile: Acamol; Algiafin; Asafen Nueva
Formula¤; Cotibin Analgesico Antipiretico; Cotibin Compuesto; Cryogenine Plus¤;
Daimeton¤; Dolo-Esan; Fibrimol¤; Geniol; Gesidol; Kitadol; Panadol; Panagesic; Parox
Meltab; Rapidol; Sinflu; Supracalm; Tapsin Infantil; Tapsin Puro sin Cafeina¤; Tapsin
Puro; Tapsin SC; Winasorb; Xumadol; Zolben; Czech Republic: Ben-u-ron; Calpol¤;
Daleron; Effect Comfort¤; Efferalgan; Gelocatil¤; Medipyrin; Mexalen; Panadol; Paralen;
Paramax Rapid; Paramegal; Perfalgan; Denmark: Arax; Pamol; Panam¤; Panodil;
Paratabs¤; Perfalgan; Pinex; Finland: Pamol F; Pamol; Panadol; Para-Hot; Para-Suppo;
Para-Tabs; Paraceon; Paramax; Perfalgan; France: Aferadol¤; Akindol¤; Algodol;
Claradol; Compralsol¤; Dafalgan; Dolflash¤; Doliprane; Dolipraneoro; Dolko; Dolotec;
Efferalgan; Efferalganodis; Expandox¤; Febrectol¤; Geluprane; Gynospasmine¤;
Malgis¤; Oralgan¤; Panadol; Paralyoc; Perfalgan; Sedarene¤; Tylenol¤; Germany:
Anaflon¤; Anti-Algos¤; Antipanin N¤; Antipanin P¤; Ben-u-ron; Captin; Contac
Erkaltungs-Trunk; Dignocetamol¤; Dolarist¤; Dolofugin¤; Doloreduct¤; Dolorfug¤;
Dorocoff-Paracetamol¤; duracetamol¤; Enelfa¤; Eu-Med P mono¤; Eu-Med
Schmerzzapfschen¤; Fensum¤; Finiweh¤; Freka-cetamol¤; Gardan P¤; Gepodan¤;
Grippex; Grippostad Heissgetrank¤; Kinder-Finiweh¤; Larylin Heissgetrank gegen
Schmerzen und Fieber¤; Logomed Schmerz- /Fieber¤; Lonarid Mono¤; Mandrogripp¤;
Mogil¤; Momentum Analgetikum¤; Mono Praecimed¤; Mono-Trimedil¤; NeoCitran¤;
NilnOcen¤; Octadon N¤; Ophinal¤; Paedialgon¤; Pantalgin¤; Parapaed; PCM¤;
Perfalgan; Pyromed¤; RubieMol¤; Schmerzex¤; Sinpro junior¤; Sinpro N¤; Togal¤;
Treupel mono¤; Tylenol¤; Verlapyrin N¤; Vips¤; Vivimed N; Vivimed¤; Greece: Anadin;
Apotel; Biocetamol; Calmodor; Cetinject; Dalminette; Depon Maximum; Depon Odis;
Depon; Dolal; Efferalgan; Genspir; Lonarid Aplo; Neo-Kalmol; Panadol; Par; Paramin;
Perfalgan; protAlgon; Tempra; Tunelzin; Tylenol; Zenol; Hong Kong: Acetamol¤;
Afebrin¤; Angenol¤; Apap¤; Arfen¤; Ben-u-ron; BF-Paradac¤; Biogesic; Calpol¤;
Martindale: The Complete Drug Reference
Children's Tylenol¤; Childrens Fortolin¤; Christamol; Cortal for Children; Dhamol;
Europain; Infant's Tylenol¤; Junior Strength Tylenol¤; Panadol; Paracet¤; Paracetal¤;
Paragram¤; Parcemol¤; Parmol; Pharmadol¤; Progesic; Serimol; Setamol; Tiffy¤;
Tylenol¤; Uni-Febrin; Uni-Pamol¤; Hungary: Ben-u-ron; Efferalgan; Febrilin;
Grippostad; Mexalen; Panadol; Paramax Rapid; Perfalgan; Rubophen; India: A-125;
Acicloflex; Alcocin; Algina; Alice; Anamol; Anthol; Asimol; Babygesic; Bactpar; Bambiti
Kid; Bepamol; Calpol; Cemol; Cetanil; Cetofeb; Cofamol; Copanat; Crocin; Cropara;
Disprin Paracetamol¤; Doliprane; Dolko; Dolo; Dolodart; Dolopar; Essmol; Eupyric;
Ezeepara; F-Nil; Fastpara; Febrex; Febridol; Febrinil; Fenace; Fenil; Fep; Fepamol;
Fepanil; Fevastin; Flupara; Genmole; Hidol; Histacold; Hitem-MD; Hitz; Ibumax; Ifimol;
Infadil; Jagcin¤; Junimol; Kelvin; Lanol; Lit-King; Lotemp; Low-Deg; Lupipara; Malidens;
Medomol; Metacin; Metalgin; Mino; Mol; Mortrin; Narmo; NBace-P; Neomol; Nofiva;
Orimol; Oyup; P-125; P-37; Pacimol; Pamol; Panact; Parabig; Paracetanal; Paracin;
Paracip; Parafizz; Parafort; Parage; Paraglow; Paral; Paralife; Parameter; Parasym;
Paratel; Parazine; PF Drops; Pyrexon; Pyrigesic; Ultragin; Indonesia: Afebrin¤;
Alphamol; Biogesic; Bodrex Forte¤; Bodrexin Demam; Calapol¤; Contratemp; Cupanol;
Dapyrin¤; Dumin; Erphamol; Farmadol; Fevrin; Grafadon¤; Gunaceta¤; Ikacetamol;
Itamol; Kamolas; Lanamol; Maganol; Moretic; Naprex; Nasamol; Nufadol; Ottopan;
Pamol; Panadol Extra; Panadol; Paracetol¤; Praxion; Progesic; Propyretic; Pyrex;
Pyrexin; Pyridol; Sanmol; Sumagesic¤; Tempra; Termorex¤; Turpan; Xepamol;
Ireland: Anadin Paracetamol¤; Calpol; Cetamol¤; Disprol¤; Dolflash; Hedex; Lemsip
Children's Cold Relief¤; Medinol; Panadol; Panagram Max; Paralief; Paralink; Parapaed;
Parasol¤; Paratabs; Perfalgan; Rimadol; Suotex¤; Tylenol¤; Israel: Abrol; Abrolet;
Acamol; Acamoli; Aldolor; Dexamol Kid; Dexamol; Efferalgan¤; Liqiprin¤; Maccabimol;
Novimol; Panadol; Paracet; Paramol; Paramolan¤; Rokamol; Sensamol; Supramol;
Vimoli; Italy: Acetamol; Adolef; Calpol¤; Efferalgan; Levadol¤; Minofen; NeoFepramol¤; Normaflu; Panadol; Perfalgan; Piros; Puernol¤; Sanipirina; Tachipirina;
Termol; Malaysia: Acet¤; Arfen; Avadol; Biogesic¤; Dhamol; Dumin¤; Hoemal;
Naprex¤; Panadol; Parafizz; Partamol; Poro; Rapidol; Remedol; Serimol¤; Setromol¤;
Tempol; Uphamol; Mexico: Abatem; Ac-Fast¤; Acetafen; Acetif; Alpirex; Amolgen;
Analmex¤; Analphen; Andopan¤; Andox¤; Antidol; Biofer; Bremotel¤; Brontonyl¤;
Calinofen¤; Calpol¤; Colderina¤; Coriver; Datril; Dismifen; Dolgan Flash¤; Dolotemp¤;
Doluvital; Dolviran; Facetol; Farpik; Febran¤; Febrim¤; Febronyl¤; Ferridal¤; Filanc;
Frilen; Ginol¤; Icetazol; Ifutemp¤; Infalgina¤; Magnidol-Plus; Mejoral Acti-Rapido;
Mejoral; Mejoralito; Minofen; Minomex¤; Neodol; Neodolito¤; Nordinet Infantil; Notem;
Martindale: The Complete Drug Reference
Panadol¤; Panofen; Parengesico¤; Pharmacen; Piraldin¤; Piralgina 650¤; Piralgina;
Piralyn; Piremol; Precifen; Prosedal; Quitadol; Resfin¤; Sedalito; Sinedol¤; Soltadol;
Sons Piral; Tafirol; Temperal; Tempire¤; Tempofin¤; Tempra; Tempre¤; Temprin;
Temzzard; Termotrin¤; Terol¤; Tylenol; Tylex; Ulpafie; Verbalem¤; Wifibrin¤;
Winasorb¤; Netherlands: Daro; Darocet¤; Democyl; Finimal Junior¤; Hedex; Kinder
Finimal¤; Lagalgin¤; Momentum; Panadol; Perfalgan; Sinaspril-Paracetamol; Tylenol;
Vicks Paracetamol; Norway: Alvedon¤; Pamol; Panodil; Paracet; Perfalgan; Pinex; New
Zealand: Disprol¤; Lemsip Cold & Flu Original, Cold & Flu Max; Pacimol¤; Pamol;
Panadol; Paracare; Parapaed; Paratabs¤; Perfalgan; Philippines: Acet; Acetadol;
Aeknil; Alvedon; Anaseran; Baropyrine; Biogesic; Biopain; Bioretic; Calpol; Clocephen;
Cloxina; Corgic; Crocin¤; Detramol; Dolexpel; Dolonil; Febrinil; Gendol¤; Geran; Gifaril
P; Kiddilets; Lexalgin; Medgenol; Myremol; Napalgin; Napran; Naprex; Nektol¤; NeoKiddielets¤; Nordex; Opigesic; Para-4-Kids; Para-IV; Paracef; Parvid; Poro; PRC;
Rapidol; Rexidol; Riber; Rongesic; Saridon; Selegesic; Sinomol; Tempain; Tempcaire;
Tempra; Teramol; Tylenol; Ultragesic; Zestagesic; Zydinol¤; Poland: Acenol; Apap;
Calpol; Codipar; Efferalgan; Gemipar; Grippostad; Novo-Gesic¤; Panadol; Perfalgan;
Tazamol¤; Portugal: Anadin Paracetamol¤; Anti-Gripe Asclepius; Atralidon; Beluron¤;
Ben-u-ron; Bisolgrip¤; Calpol¤; Cetol; Cofedron; Dafalgan; Efferalgan; Febridol;
Fludeten¤; Gelocatil; Huber¤; Katagrip¤; Kelin¤; Lisopan; Molpireos; Neogrip; Olpira¤;
Panadol; Panasorbe; Pantadolor; Paracetol; Paramolan; Parsel; Perdolan Mono¤;
Perfalgan; Singrips; Supofen; Takipirina; Tylenol; Xumadol; Zaramol¤; Russia: Apap
(Апап); Calpol (Калпол); Cefecon D (Цефекон Д); Daleron (Далерон); Dolomol
(Доломол)¤; Efferalgan (Эффералган); Flutabs (Флютабс); Panadol (Панадол);
Perfalgan (Перфалган); Strimol (Стримол); South Africa: Anadin-3¤; Antalgic;
Arcanagesic¤; Brunomol¤; Calpol; Cetapon¤; Compu-Pain¤; Dolorol¤; Doxypol¤;
Dynadol¤; Empaped; Ennagesic¤; Entalgic¤; Farmacetamol¤; Fevamol¤; Go-Pain P;
Junior Disprin¤; Lyteca¤; Maxadol-P¤; Medpramol¤; Merck-Gesic¤; Micro-Gesic¤;
Napamol; Pacimol¤; Painamol; Pamol¤; Panado; Paracet; Paradco¤; Paramed¤;
Perfalgan; Prolief; Pyradol¤; Pyragesic¤; Pyralen; Setamol¤; Temol¤; Tylenol; Varipan;
Winpain¤; Singapore: Acet; Alcetamol; Biogesic; Calpol; Cetamol; Childrens Panadol;
Dhamol; Dolo; Double Parrot Brand; Familin; Fepril; Fibrexin¤; Hoemal; Kame; Mei-Mei
Children's Fever; Milidon¤; Napa; Naprex¤; Pacemol; Panadol; Panamol; Paramol-F;
Paratab; Parcemol; Parmol; Paximol; Poro; Progesic; Rapidol; Remedol; Senkon Junior
Fever; Setamol; Sunny Fever; Tempra¤; Tylenol; Uphamol; Spain: Acecat; Acertol;
Actron¤; Akindol¤; Alador; Alginina¤; Analter¤; Antidol; Apiretal; Aspac¤; Asplin¤;
Martindale: The Complete Drug Reference
Auxidor¤; Bandol¤; Bolidol¤; Calmanticold¤; Cupanol¤; Dafalgan; Desfebre¤; Dolefin
Paracetamol¤; Dolgesic¤; Dolostop; Drazin¤; Duorol; Efetamol¤; Efferalgan; Eftazid¤;
Febranine¤; Febrectal; Frenagial¤; Gelocatil; Hedex¤; Melabon Infantil¤; Nofedol¤;
Nupeldol; Octomol; Panadol; Panrectal¤; Parafludeten; Pediapirin¤; Perfalgan;
Pirinasol¤; Prontina¤; Resakal¤; Resolvebohm; Sinmol; Stopain¤; Sudafed Co¤; Talgo¤;
Temperal¤; Tempra¤; Termalgin; Termocatil¤; Tylenol; Xumadol; Zatinol¤; Zolben¤;
Sweden: Alvedon; Curadon¤; Lemsip¤; Pamol; Panodil; Perfalgan; Reliv; Switzerland:
Acetalgin; Bebesan N¤; Becetamol; Ben-u-ron; Comprimes analgesiques no 534¤;
Contre-Douleurs P; Dafalgan; Democyl¤; Demogripal¤; DoloStop nouvelle formule¤;
Dolprone; Fortalidon P¤; Influbene N; Kafa¤; Malex¤; Neo-Treupine¤; Nina¤;
Ortensan¤; Osa Suppositoires contre douleurs et fievre¤; Panadol Extend; Panadol;
Para-schmerz¤; Perfalgan; Pharmacard Family Douleurs & Fievre¤; Rivodol¤; Seranex
N¤; Siniphen Nouvelle formule¤; Spalt N¤; Stellacyl nouvelle formule¤; Termalgin¤;
Treupel Dolo Paracetamol; Treupel N¤; Treuphadol¤; Tylenol; Zolben; Thailand: A-Mol;
Aceta-P; Aceta; Acetasil¤; Algogen; Ampol; Angela; Antispa Plus; Aoricet; Asumol;
Bakamol; Biogesic¤; Calpol; Cemol; Cetamol; Cetapol; Cetta; Codamol; Cotemp; Daga;
Denamol; Depyret; Detamol¤; Diamol; Faron; Fenn¤; Foramol; Icolid Plus; KB Gin; Kit;
Lotemp; M-Aceta; Mymol; Mypara; Nasa; New-um; Newtol; Nutamol¤; Pamol; Panadol;
Para-G; Para; Paracap; Paracet; Paragin; Paraman; Paramed; Paramol TP; Paramol;
Paranal-L¤; Paranal¤; Parano; Paranol; Parapro; Parat; Paratol¤; Parcet¤; Pardon;
Partamol; Pat; Patum; Pemol; Poro; Pyracon; Pyretal¤; Pyrimed; Ramol; Saebegin;
Salenol; Sara; Saridon¤; Sinogesic; Somagin¤; Temnol; Temolan¤; Tempra; Thoho; TM
Gin¤; Totamol; Tumdi¤; Tylenol; Tymol; Umeda Para-J; Unicap¤; Unimol; Uracet¤;
Vemol; Vetamol; Vikool; Xebramol; Turkey: A-Per; Asomal; Babinoks; Berko-Setamol;
Calpol; Derman; Durapan; Efferalgan; Efpa; Ekosetol; Geralgine-P; Gripin; Kataprin;
Medaset; Minafen; Minoset; Noral¤; Panadol; Para-Nox; Paracet; Paradine; Parasedol;
Parcetol; Parol; Paroma; Pedipar; Perfalgan; Pharmadol; Pirofen; Polmofen; Sedalon;
Seskamol; Setamol; Sifenol; Tamol; Tempo; Termacet; Termalgine; Tylol; Vermidon;
Volpan; Zaldaks; United Arab Emirates: Adol; United Kingdom: Abdine Cold Relief;
Alvedon; Anadin Paracetamol; Aspro Paraclear¤; Boots Pain Relief Suspension 6 Years
Plus; Calpol; Disprol; Elkamol¤; Fanalgic¤; Fennings Childrens Cooling Powders;
Galpamol; Hedex; Infadrops; Mandanol; Medinol; Miradol¤; Obimol; Pain Relief Syrup
for Children¤; Paldesic; Panadol; Panaleve; Paracets; Paraclear; Paramin¤; Parapaed;
Perfalgan; Placidex¤; Salzone; Tixymol¤; Tramil¤; Ukraine: Cefecon D (Цефекон Д);
Daleron Cold 3 (Далерон Колд 3); Glycodin (Глікодин); Milistan For Children (Мілистан
Martindale: The Complete Drug Reference
Дитячий)¤; Panadol (Панадол); Rapidol (Рапидол); United States: Acephen; Aceta;
AlbaTemp¤; Alka-Seltzer Advanced Formula¤; Apacet; Apap; Apra; Arthritis Foundation
Pain Reliever, Aspirin Free¤; Arthritis Pain Formula Aspirin Free; Aspirin Free Anacin;
Aspirin Free Pain Relief; Bromo Seltzer; Childrens Dynafed Jr¤; Childrens Mapap;
Comtrex Maximum Strength Sore Throat; Dapa¤; Dolanex¤; Dolono; Dorcol Children's
Fever & Pain Reducer¤; Dynafed EX¤; Extra Strength Datril¤; Feverall; Genapap;
Genebs¤; Halenol; Infantaire; Liquiprin; Mapap; Maranox; Meda¤; Myapap¤; Neopap¤;
Ofirmev; Oraphen-PD; Panadol; Panex¤; Panitone; Phenaphen¤; Redutemp; Ridenol;
Silapap; Snaplets-FR¤; St. Joseph Aspirin-Free for Children¤; Suppap¤; Tapanol¤;
Tempra; Triaminic Infant's Fever Reducer/ Pain Reliever; Tylenol Sore Throat Daytime;
Tylenol; UN-Aspirin; Uni-Ace; Valadol¤; Venezuela: Acetafen; Acetalis; Aceval; Agurin;
Alivax; Amifen; Ananty; Apiret; Apyrene; Atamel; Brexin; Cadafen¤; Colprin¤;
Menpirin¤; Paracor; Parstelin¤; Tachipirin; Tempra; Tylenol; Tylex; Vestax; Winadol¤;
Multi-ingredient Preparations (Latest modification: 06-Feb-2012)
The symbol ¤ denotes a preparation which is discontinued or no longer actively
marketed.
Argentina: Agrip; Algicler; Algio-Truxa¤; Algiseda Plus; Algiseda; Antigripal
Compuesto; Apracur Antigripal; Apracur Te Descongestivo; Apracur; Aseptobron
Antigripal; Befol Plus; Benadryl Day & Night; Bio Grip 4; Bio Grip Classic; Bio Grip Plus;
Bio Grip-T Descongestivo; Blokium Gesic; Buscapina Compositum N; Calmador Plus;
Calmapir-P¤; Causalon Gesic¤; Causalon Grip; Cefalex Plus; Clarifriol; Cloq Plus; CorTagrip; Coris Grip; Corizina; Craun¤; Daygrip; Decidex Compuesto; Desenfriol
Decongestivo; Desenfriol Hiper T¤; Di-Neumobron; Di-Neumobron; Di-Neumobron;
Diclogesic Forte; Diclolabsa Gesic; Dioxadol; Dioxaflex Gesic; Dirox Aler; Dolanet;
Dolofrix; Doma Grip; Doxtran Gesic; Dristan Descongestivo; Duflegrip; Espasmol;
Everfem; Factor Antigripal; Factus; Fadagrip; Falgos; Farintos; Febrigrip; Finagrip Forte;
Finagrip¤; Fugafebril; Fullgrip; GNO CP; Gripaben Descongestivo; Gripaben; Gripanil C;
Gripequin; Hidronovag Complex; Ideogrip; Inmunogrip C; Inmunogrip; Itedal Plus;
Kiper; Klipal¤; Letondal; Listaflex Forte; Loremex Antigripal¤; Matrix Grip Antigripal;
Matrix Grip¤; Matrix Migra; Mejoral Cafeina; Mejoral Grip T Descongestivo; Mejoral Grip;
Metaflex Gesic; Multin; Nastizol Compositum; Nexogrip; Oxafem; Oxagesic; Oxinovag
Complex; Panclogesic; Panotos NF; Panotos; Paracetamol Grip NF; Paraflex AN; Paraflex
Plus; Parageniol Caff; Parageniol Grip Caliente; Parageniol Grip¤; Parsel¤; Pirigrip;
Martindale: The Complete Drug Reference
Predual¤; Pulmonix Grip; Qura; Reanima; Refrianex Antigripal; Refrianex Compuesto;
Refrianex; Resaca; Rodinac Gesic; Rondec Compositum¤; Rupediol; Sandival NF¤;
Sandival; Saridon; Sindrolen Vitaminado¤; Sinutab; Tabcin Antigripal; Tabcin Caliente
Descongestivo; Tabcin Compuesto; Tabcin D; Tabcin Rapida Accion; Tafirol Artro; Tafirol
Mujer; Tafirol T Caliente Plus; Tavinex Antigripal; Termogrip; Tetralgin APC; TramaKlosidol Plus¤; Tramacet; Tramal Plus; Uvasal Doble Accion; Valuca Plus; Venter;
Vesalion Gesic; Vick Vitapyrena Forte; Viclor Grip; Wilpan Antigripal; Xedenol Gesic;
Australia: Anagraine; Analgesic/Calmative¤; Angesil Plus¤; Benadryl Cold and Flu¤;
Bethal¤; Capadex; Chemists Own Cold & Flu Day/Night; Chemists Own Cold & Flu Relief;
Chemists Own Coldeze; Chemists Own Dolased Day/Night Pain Relief; Chemists Own
Hayfever Sinus Relief; Chemists Own Pain; Chemists Own Sinus-Pain Relief; Childrens
Panadol Cold Relief Elixir¤; Codalgin Plus; Codalgin; Codapane; Codinol¤; Codral 4 Flu;
Codral Cold & Flu + Cough New Formula; Codral Cold & Flu New Formula; Codral Day &
Night New Formula; Codral Nightime; Codral Original Cold & Flu + Cough Day & Night;
Codral Original Cold & Flu Max; Codral Original Cold & Flu; Codral Original Day & Night
Cold & Flu; Codral Pain Relief¤; Codral Tension Headache¤; Cold & Flu (Non-Drowsy)
Tablets¤; Cold & Flu Tablets Non Drowsy¤; Cold & Flu Tablets¤; Coldrex Cold and Flu
Capsules¤; Comfarol Forte; Cyclopane¤; Day & Night Cold & Flu; Demazin Cold & Flu;
Demazin Cough, Cold & Flu; Demazin Day & Night; Demazin PE Cold & Flu Relief;
Demazin PE Day & Night Cold & Flu Relief; Di-Gesic; Dimatab Cold Tablets¤; Dimetapp
Cold & Flu Day Relief; Dimetapp Cold & Flu Night Relief; Dimetapp Cold, Cough & Flu¤;
Dimetapp Cold, Cough & Flu; Dimetapp Elixir-Plus¤; Dimetapp Sinus Relief¤; Dolaforte¤;
Dolased; Doxitab Cold Tablets¤; Dymadon Co¤; Dymadon Forte¤; Febricod¤; Febridol
Plus; Fiorinal; Headclear¤; Hexal Comfarol Plus¤; Junicol Junior¤; Junicol V¤; Kiddy
Calm Plus¤; Lemsip Pharmacy Flu Strength Daytime; Lemsip Pharmacy Flu Strength
Nightime; Lemsip Pharmacy Max Cold & Flu + Chesty Cough; Lemsip with
Decongestant; Liquigesic Co¤; Logicin Cough & Cold¤; Logicin Flu Strength Day & Night;
Logicin Flu Strength¤; Logicin Hay Fever¤; Maxydol; Medimonth¤; Menstraleve¤;
Mersyndol Daystrength; Mersyndol; Metomax; Migranol¤; Migrex Pink¤; Migrex Yellow¤;
Mucron¤; Nembudeine¤; Norgesic; Nyal Nasal Decongestant + Pain Relief PE; Nyal
Plus+ Cold & Flu¤; Nyal Plus+ Day & Night Cold & Flu¤; Nyal Plus+ Day Night Sinus
Relief¤; Nyal Plus+ Sinus Relief with Antihistamine¤; Nyal Sinus + Pain Relief PE; Ordov
Extra Day & Night Cold and Flu¤; Ordov Febrideine¤; Ordov Migradol¤; Ordov Sinus &
Hayfever¤; Orthoxicol 1¤; Orthoxicol 2¤; Orthoxicol 3¤; Orthoxicol 4 and 6¤; Orthoxicol
8 and 9¤; Orthoxicol Cold & Flu¤; Orthoxicol Day & Night Cold & Flu¤; Orthoxicol Dry
Martindale: The Complete Drug Reference
Cough¤; Orthoxicol Headcold¤; Orthoxicol Night Cold & Flu¤; Paineze¤; Painstop DayTime Pain Reliever; Painstop Night-Time Pain Reliever; Panadeine Plus¤; Panadeine;
Panadol Allergy Sinus¤; Panadol Cold & Flu Relief PE; Panadol Cold & Flu; Panadol Elixir
with Promethazine¤; Panadol Flu Strength Day & Night PE; Panadol Night¤; Panadol
Sinus Day & Night; Panadol Sinus Relief PE; Panadol Sinus; Panalgesic; Panamax Co;
Panquil¤; Paradex; Pentalgin¤; Percodan¤; Pharma-Col Junior¤; Polaramine Infant
Compound¤; Prodeine; SBPA Analgesic/Calmative¤; Seda-Quell¤; Seneplus¤; Sigma
Relief Cold Tablets¤; Sinuguard N/F Without Antihistamine¤; Sinuguard With
Antihistamine¤; Sinutab Antihistamine¤; Sinutab Sinus & Pain Relief; Sinutab Sinus
Allergy & Pain Relief; Sinutab with Codeine¤; Sinuzets Cold and Flu Capsules with
Antihistamine¤; Sinuzets Cold and Flu Capsules¤; Sudafed PE Sinus Allergy & Pain
Relief; Sudafed PE Sinus Day & Night; Sudafed PE Sinus Pain Relief; Sudafed Sinus Day
& Night Relief; Sudafed Sinus Pain & Allergy Relief; Sudafed Sinus Pain Relief;
Tensodeine; Triolix Day-time¤; Triolix Night-time¤; Tylenol Allergy Sinus¤; Tylenol Cold
& Flu Non-Drowsy¤; Tylenol Cold & Flu¤; Tylenol Sinus¤; Vicks Headclear Nondrowsy¤;
Vicks Headclear¤; Austria: Ado C¤; Adolorin; Adoluron CC¤; Algofina¤; APA¤; Aplexil¤;
Apracur¤; Asticol¤; Buscopamol¤; Co-Tylenol¤; Coldadolin¤; Coldagrippin¤;
Contralorin¤; Dolenso¤; Dolmix¤; Dolocod¤; Dolokapton¤; Dolomo Nacht¤; Dolomo;
Dolonerv; Dolopharm¤; Duan; Duaneo mit Codein¤; Duokapton¤; Eu-Med¤; Gewadal;
Grippostad C; Ilvico mit Vitamin C¤; InfluASS; Influbene¤; Irocopar c C¤; Irocophan;
Kratofin¤; Melabon; Mexa-Vit C; Migradon; Neo Citran; Neokratin¤; Nervan; Norgesic;
Panax¤; Parafon¤; Peremin¤; Rapidol; Ratiopyrin¤; Rilfit¤; Sanalgit¤; Saridon; Sigmalin
B6 forte¤; Sigmalin B6 ohne Coffein¤; Sigmalin B6¤; Talvosilen¤; Thomapyrin mit Vitamin
C; Thomapyrin; Toximer¤; Trancopal compositum¤; Trimedil compositum¤; Trimedil
plus C; Ultrapyrin¤; Veganin¤; ViCetamol¤; Vivimed; Waldheim Schmerztabletten¤;
Wick Erkaltungs-Saft fur die Nacht¤; Wick Erkaltungssirup fur die Nacht; Zaldiar;
Belgium: Afebryl; Algidol¤; Algocod; Algophene; Algostase; Antigriphine; Antigrippine
Midy¤; Asodal; Croix Blanche; Dafalgan Codeine; Distalgic¤; Docparacod; Dol-Stop¤;
Efferalgan C¤; Finimal¤; Kranit Nova¤; Latepyrine¤; Lonarid N; Mann; Migraine-Kranit
Nova¤; Migraine-Kranit¤; Neomeritine¤; Neuridon Forte¤; Nevrine Codeine; Niocitran;
Panadeine¤; Panadol Codeine; Panadol Plus; Perdogrip¤; Perdolan Codeine; Perdolan
Compositum¤; Perdolan Compositum; Perdolan Mono C¤; Pontalsic; Rectoplexil¤;
Rhinofebryl; Saridon¤; Sinutab; Toplexil; Trimedil¤; Troc; Veganine¤; Yamalen¤;
Zaldiar; Brazil: Algafan¤; Algi Peralgin¤; Algi-Butazolon¤; Algi-Danilon¤; AlgiItamanil¤; Algi-Reumac¤; Algi-Reumatril; Algi-Tanderil¤; Algifen¤; Algiflamanil;
Martindale: The Complete Drug Reference
Alginflan¤; Algizolin¤; Analtrix¤; Analverin Plus¤; Antigripine¤; Asafen¤; Beserol; Bromil
Grip; Buscopan Plus; Butapirin¤; Butazil¤; Cedrilax¤; Cefadrin; Cefalium; Cibalena A;
Cimegripe; Codex; Coficold-Ped¤; Coldrin; Corizin; Day Time Liquigels¤; Descon¤;
Descon; Diatyl; Diclofetamol; Doralem¤; Dorend¤; Dorex¤; Dorilax; Dorpinol¤;
Dorserol¤; Elcodrix¤; Essedin; Excedrin; Febupen; Flamanan; Flexalgin; Fluviral¤;
Forgrip¤; Gegrip¤; Grifenol¤; Gripcaps C¤; Gripen F; Gripen; Gripeol; Gripionex¤;
Maxidrin; Mio-Citalgan; Mioflex A; Mioflex; Multigrip; Naldecon Bebe; Naldecon Dia;
Naldecon Noite; Naldecon; Naldecon; Nasaliv; Nasaliv; Nasogrip¤; Neogrein; Neolefrin
Baby; Neolefrin; Night Time Liquigels¤; Notuss; Ormigrein; Otonal¤; Paceflex¤; Par;
Paralon; Parcel; Parenzyme Analgesico; Probenzima Analgesico¤; Redentil¤; Regulador
Gesteira¤; Rescold¤; Resfenol; Resfrineo¤; Resfry; Resfry; Resfryneo; Resprin; Reuplex;
Sanilax; Saridon; Sedalmerck¤; Sedilax; Sinutab¤; Sonridor Caf; Stilgrip; Tandene;
Tanderalgin; Tandrex A¤; Tandriflan; Tandrilax; Tiratosse¤; Toplexil; Torsilax; Trilax¤;
Trimedal; Tylenol DC; Tylenol Sinus; Tylex; Ultracet; Veramon¤; Vick Pyrena; Vitalen
C¤; Canada: Acet Codeine; Acet-2, Acet-3; Acetaminophen with Codeine; Acetazone
Forte C8; Acetazone Forte; Actifed Plus; Actifed-A¤; Allergy + Sinus Relief; Allergy Sinus
Headache; Allergy Sinus Nighttime Relief¤; Allergy Sinus; Atasol-8, -15, -30; Back-Aid;
Balminil Cough & Flu; Benadryl Allergy/Sinus Headache; Benadryl Total/Allergy; Benylin
1 Cold and Flu Day Night¤; Benylin 1 Cold and Flu Nightime; Benylin 1 Cold and Flu;
Benylin All-in-One Cold & Flu Night; Benylin All-In-One Cold and Flu Night PE; Benylin
Cold & Sinus Night; Benylin Cold & Sinus Plus; Benylin Cold & Sinus; Benylin Cough &
Cold with Extra Strength Acetaminophen; Benylin for Children All-In-One Cold & Fever
Nightime; Benylin for Children All-In-One Cold & Fever; Buckley's Complete Extra
Strength Cough, Cold & Flu Day; Buckley's Complete Extra Strength Cough, Cold & Flu
Night; Buckley's Complete; Buckley's Daytime Cold and Sinus; Buckley's Nighttime Cold
and Sinus; Buckley's Sinus Pain Relief¤; Calmylin Cough & Flu¤; Childrens Tylenol Cold
and Cough; Childrens Tylenol Cold; Childrens Tylenol Cough and Runny Nose; Childrens
Tylenol Decongestant; Citron Chaud¤; Cold & Flu Capsules; Cold & Flu Daytime; Cold &
Flu Nighttime; Cold & Flu Relief; Cold Flu Relief; Cold Medication D; Cold Medication
Daytime Relief¤; Cold Medication N; Cold Medication Nighttime Relief¤; Cold Relief
Daytime; Cold Relief Nightime; Cold/Flu Medicine; Coldaside Cold & Flu; Coltalin Cold &
Allergy; Contac Cold & Fever¤; Contac Cold & Sore Throat Non Drowsy; Contac Cold &
Sore Throat¤; Contac Cold Chest Congestion; Contac Complete Cough Cold & Flu Non
Drowsy; Contac Complete Cough Cold and Flu Day & Night¤; Contac Complete Cough,
Cold & Flu; Contac Cough and Sore Throat¤; Contac Cough Cold and Flu¤; Contac
Martindale: The Complete Drug Reference
Cough, Cold & Flu Nighttime¤; Contac Day & Night Sinus/Allergy¤; Contac Day¤; Contac
Night Cough¤; Contac Night-Time Hot Drink¤; Contac Sinus¤; Coricidin D¤; Coricidin II
Cold and Flu; Coricidin II Extra Strength Cold and Flu; Coricidin Sinus Headache¤;
Cough & Flu Syrup¤; Cough Cold and Flu; Cough; Day Relief Cold and Flu¤; DayQuil
Cold & Flu; DayQuil D; Daytime Cold & Flu; Daytime Cold and Flu Relief; Daytime Cold
Relief; Daytime Cold/Flu; Daytime Liqua; Daytime Sinus Relief; Dilotab II; Dilotab¤;
Dimetapp Daytime Cold; Dimetapp Nighttime Cold; Dimetapp Oral Infant Cold & Fever
Drops¤; Dimetapp-A Sinus¤; DM Decongestant-Expectorant-Analgesic¤; Dodds Back
Ease¤; Dristan N D; Dristan; Empracet¤; Endocet; Excedrin; Exdol; Extra Strength
Acetaminophen with Codeine¤; Extra Strength Allergy Sinus; Extra Strength Cold
Medication Daytime Relief; Extra Strength Cold Medication Nightime¤; Extra Strength
Cold Medication Nighttime Relief¤; Extra Strength Contac Cold & Sore Throat; Extra
Strength Contac Complete Cough, Cold & Flu; Extra Strength Daytime Cold Relief PE;
Extra Strength Daytime Cold Relief; Extra Strength Daytime Flu PE; Extra Strength Flu
Relief Daytime; Extra Strength Flu Relief Nightime; Extra Strength Head Cold and Sinus;
Extra Strength Multi-Symptom PMS Relief; Extra Strength Muscle & Back Pain Relief;
Extra Strength Nighttime Cold Relief PE; Extra Strength Nighttime Cold Relief; Extra
Strength Nighttime Flu PE; Extra Strength Sinus and Congestion Relief¤; Extra Strength
Sinus Relief Nighttime; Extra Strength Sinus Relief; Gin Pain¤; Grippalin & C¤;
Grippalin¤; Histenol Cold¤; Histenol II; Hot Lemon Relief for Symptoms of Cold and Flu;
Hot Lemon Relief for Symptoms of Cough, Cold & Flu; Hot Lemon Relief; Hot Lemon¤;
Jack & Jill Cough Cold & Flu; Junior Strength Cold DM¤; Lemon Time¤; Little Colds MultiSymptom Cold Formula; Maux de Gorge et de la Toux; Medicament Sinus pour La Nuit;
Medicament Sinus; Menstrual Midol; Mersyndol with Codeine; Methoxacet-C;
Methoxacet; Midol Extra Strength¤; Midol Multi-Symptom¤; Midol Night-Time; Midol
PMS; Midol Teen; Multi-Symptom PMS Relief; Muscle & Back Pain Relief-8; Muscle &
Back Pain Relief; Nasal & Sinus Cold Formula¤; Neo Citran Calorie Reduced¤; Neo Citran
Chest Congestion & Cough¤; Neo Citran Cold & Flu¤; Neo Citran Colds & Flu; Neo Citran
Coughs Colds & Flu; Neo Citran Daycaps¤; Neo Citran Extra Strength Cold & Sinus; Neo
Citran Non Drowsy Cold & Flu¤; Neo Citran Sinus¤; Neo Citran Sore Throat & Cough;
Neo Citran Total¤; Neo Citran¤; Neocitran Extra Stength Daytime Total Plus Mucus
Relief; Neocitran Extra Stength Daytime Total; Neocitran Extra Strength Chest
Congestion Cold & Mucous Relief; Neocitran Extra Strength Cold and Flu; Neocitran
Extra Strength Nighttime Total; Neocitran Nighttime Total Cold & Flu; Night Relief Cold &
Flu¤; Nighttime Cold & Flu Relief; Nighttime Cold & Flu; Nighttime Cold and Flu-In-One;
Martindale: The Complete Drug Reference
Nighttime Cold Relief; Nighttime Contac Cold & Sore Throat; Nighttime Contac Complete
Cough, Cold & Flu; Nighttime Extra Strength Contac Cold & Sore Throat; Nighttime Extra
Strength Contac Complete Cough, Cold & Flu; Nighttime Super Strength Contac
Complete¤; Nighttime Total Cold and Flu; Nighttime; Nitetime Cold Medicine; Non
Drowsy Contac Complete¤; Non Drowsy Super Strength Contac Complete¤; Novahistex
Sinus¤; Novahistex¤; Novo-Gesic C; NyQuil¤; Obusforme¤; Painaid PMF; Pamprin;
Parafon Forte C8¤; Parafon Forte¤; Percocet; Personnelle Contre le Rhume¤; ratioEmtec; ratio-Lenoltec No 1, No 2, No 3; ratio-Lenoltec No 4; ratio-Oxycocet; Regular
Strength Cold Daytime Relief¤; Regular Strength Cold Nighttime Relief¤; Regular
Strength Flu Relief Nightime; Regular Strength Sinus Medication; Regular Strength
Sinus¤; Relaxophen; Relievol Allergy Sinus; Relievol PMS; Relievol Sinus; Rhume et de
la Grippe; Rhume et Grippe; Rivacocet; Robaxacet-8; Robaxacet; Robitussin Cough,
Cold & Flu¤; Robitussin Honey Flu¤; Robitussin Total Cough, Cold & Flu Nighttime;
Robitussin Total Cough, Cold & Flu; Rounox + Codeine¤; Roxicet¤; Sine-Off Allergy¤;
Sine-Off ND¤; Sinugex¤; Sinus & Congestion Relief¤; Sinus Medication Day; Sinus
Medication Night; Sinus Medication¤; Sinus Medication; Sinus Pain & Nasal Congestion
Relief; Sinus Relief; Sinutab Extra Strength Daytime/Nightime¤; Sinutab Extra Strength;
Sinutab ND Extra Strenth; Sinutab ND; Sinutab Nightime; Sinutab NT; Sinutab Regular;
Sinutab Sinus & Allergy 12 Hour¤; Sinutab Sinus (Daytime) Non Drowsy¤; Sinutab Sinus
and Allergy; Sinutab Sinus Non Drowsy; Sinutab with Codeine; Spasmhalt; Sudafed Cold
& Cough; Sudafed Cold & Flu¤; Sudafed Head Cold & Sinus; Sudafed Sinus¤; Tempra
Cold Care¤; TheraFlu Cold & Flu; TheraFlu Flu, Cold & Cough¤; Total Cold and Flu;
Tramacet; Trendar PMS¤; Triaminic Cold & Fever¤; Triaminic Cold Cough & Fever;
Triaminic Cough & Fever¤; Triaminic Cough & Sore Throat; Triaminic Cough & Sore
Throat; Triaminic Fever & Cough; Triaminic Nighttime Flu¤; Triaminic Throat Pain &
Cough¤; Triaminicin with Codeine¤; Triaminicin¤; Triatec-30; Triatec-8; Tylenol Aches &
Strains¤; Tylenol Allergy Sinus Nighttime; Tylenol Allergy Sinus; Tylenol Allergy-D¤;
Tylenol Allergy; Tylenol Back Pain; Tylenol Childrens Cold & Cough Nighttime; Tylenol
Childrens Cough & Runny Nose; Tylenol Cold & Flu (Nighttime Relief)¤; Tylenol Cold &
Sinus Daytime; Tylenol Cold & Sinus Nighttime; Tylenol Cold (Chest Congestion)¤;
Tylenol Cold and Flu Daytime; Tylenol Cold and Flu Nighttime; Tylenol Cold and Flu
Powder¤; Tylenol Cold Daytime; Tylenol Cold DM; Tylenol Cold Infant's¤; Tylenol Cold
Medication¤; Tylenol Cold Nighttime; Tylenol Cold Rapid Release; Tylenol Complete Cold
Cough & Flu; Tylenol Cough with Decongestant¤; Tylenol Cough; Tylenol Flu Daytime;
Tylenol Flu Nighttime Gelcap; Tylenol Flu Nighttime; Tylenol Menstrual; Tylenol No 1;
Martindale: The Complete Drug Reference
Tylenol No 2 with Codeine or Tylenol No 3 with Codeine; Tylenol No 4 with Codeine;
Tylenol No. 3 with Codeine without Caffeine¤; Tylenol Sinus (Daytime Relief)¤; Tylenol
Sinus (Nighttime Relief)¤; Tylenol Sinus Children's¤; Tylenol Sinus Daytime; Tylenol
Sinus Nighttime; Tylenol Sinus Pain and Congestion Daytime; Tylenol Sinus Pain and
Congestion Nighttime; Tylenol Sinus; Tylenol Ultra Relief; Tylenol with Codeine; Ultra
Headache Relief; Veganin¤; Vicks Custom Care Cough & Cold PM; Vicks DayQuil Cold &
Flu Multi-symptom Relief; Vicks DayQuil Sinus; Vicks Formula 44M; Vicks Nyquil Cold &
Flu; Vicks Nyquil Sinus; Zicam Multi-Symptom Cold & Flu Daytime¤; Zicam MultiSymptom Cold & Flu Nighttime¤; Chile: Acamol Compuesto¤; Adalgen¤; Adona¤;
Algion¤; Anacin Max; Analgex Sap; Andil¤; Anticold¤; Aprix-DN¤; Artritapsin; Beserol-S;
Biogrip Forte; Brevex; Captus¤; Codeipar; Completax Plus¤; Congestex; Cortigrip
Dia/Noche; Cortigrip; Cotibin Antigripal; Cotibin Compuesto¤; Cotibin Dia y Noche;
Cotibin Flu Dia y Noche; Cotibin Flu¤; Cotibin Plus; Cronus; Crotax; Desdol; Desenfriol
con Paracetamol¤; Desenfriolito Con Paracetamol¤; Dianoct¤; Dolean; Dolider; Dolo
Winasorb; Dolo-Esan Periodo Menstrual; Dolo-Niofen; Dolo-Octirona; Dolorelax¤;
Dolorsin; Doloten; Emagrim; Esamisol Compuesto Dia y Noche; Esamisol Compuesto;
Fibrorelax; Flectadol; Frenacol¤; Fullgrip Dia y Noche; Fullgrip; Gedol¤; Geniol
Compuesto; Geniol Flu DN; Geniol Flu; Geniol-P Compuesto con Clorfenamino¤; Glenol¤;
Gripasan Compuesto DN; Gripasan Compuesto; Gripasan Nueva Formula; Gripexin
Limonada Caliente¤; Gripexin Nueva Formula C/Pseudoefedrina; Gripexin Nueva
Formula Compuesto¤; Grisux Dia y Noche; Ibu Kitadol; Ibupirac Compuesto; Kitadol Flu
Noche¤; Kitadol Flu¤; Kitadol Max; Kitadol Noche; Kitadol Periodo Menstrual; Midol¤;
Migratapsin¤; Migrax; Minfaden; Minidol Plus; Naldecol Compuesto¤; Naldecol¤;
Nastifrin Compuesto DN; Nastifrin Compuesto; Nastizol Compositum; Nastizol DiaNoche; Nastul Compuesto; Nastul Dia y Noche; Naxodol Plus; Neogrip; No-Flu; Nogryp;
Norgesic¤; Panadol Compuesto¤; Panadol Plus; Panagesic Con Cafeina; Panagesic
Periodo Menstrual; Parsel¤; Pectobronc Plus; Pramol¤; Predual; Predual; Prefem¤;
Rinoven Compuesto; Robi-Flu¤; Saridon¤; Sedalmerck¤; Sentual Periodo; Sin-Algin;
Sinutab; Tapsin 2 Analgesico¤; Tapsin Analgesico; Tapsin Compuesto con Clorfenamina;
Tapsin Compuesto Dia/Noche Plus; Tapsin Compuesto DN; Tapsin Compuesto; Tapsin
Forte Recubiertos; Tapsin Limonada D.N.¤; Tapsin Limonada Dia¤; Tapsin Limonada
Noche¤; Tapsin Nocturno; Tapsin Periodo Menstrual; Tapsin Periodo Premenstrual;
Tapsin Up¤; Tapsininstaflu Compuesto Plus; Tapsininstaflu DN; Termo-Niofen; TimarolPar; Tonoflex; Trigesico¤; Trio Val Dia y Noche; Trio Val; Tusminal Compuesto¤;
Veradin¤; Winasorb Flex; Winasorb Flu DN; Winasorb UP; Winpac¤; Zafin; Zaldiar;
Martindale: The Complete Drug Reference
Zaledor-P; Czech Republic: Acifein; Ataralgin; Coldrex Horky; Coldrex Junior; Coldrex
MaxGrip; Coldrex Nite; Coldrex; Dafalgan Codeine¤; Daleron proti chripce a nachlazeni;
Doreta; Efferalgan Codeine¤; Efferalgan Vitamin C; Excedrinil; Febrisan; Fervex¤;
Grippostad C¤; Grippostad Horky Napoj¤; Guajanal¤; Humex Cold; Korylan; Mexavit¤;
Migraeflux¤; Migranerton; Nedolon P¤; Panadol Extra; Panadol Plus Grip; Panadol Ultra;
Paralen Extra; Paralen Grip; Paralen Hot Drink; Paralen Plus; Paramax Combi;
Paraskorbin¤; Partramec; Prodeine¤; Rhinoval C¤; Saridon; Scutamil C¤; Solpadeine¤;
Spasmopan; Talvosilen; Thomapyrin¤; Tomapyrin C¤; Tomapyrin; Traparac; Trigrip;
Ultracod; Valetol; Vicks SymptoMed Complete; Vicks SymptoMed; Vicks TriActin
Complete; Wick Medinait¤; Zaldiar; Denmark: Arax Extra; Citodon¤; Fortamol;
Kodipar; Pinex Comp; Finland: Codaxol; Dolan; Gepacod¤; Norgesic; Panacod; Panadol
Comp; Panadol Hot; Paramax-Cod; Somadril Comp¤; France: Actifed Rhume jour et
nuit; Actifed; Actron; Afebryl¤; Algicalm; Algisedal; Algoced¤; Algotropyl; Arhumyl¤;
Arpha¤; Benadryl¤; Broncorinol etats grippaux¤; Broncorinol rhume¤; Calgluquine¤;
Cefaline Hauth; Cetafeine¤; Claradol Cafeine; Claradol Codeine; Codoliprane;
Compralgyl; Contragrippine¤; Coquelusedal Paracetamol Nourrissons¤; Coquelusedal
Paracetamol; Dafalgan Codeine; Dextroref¤; Di Dolko¤; Di-Antalvic¤; Diadupsan¤;
Dialgirex¤; Dioalgo¤; Doli Rhume; Dolidon; Doliprane Vitamine C; DolirhumePro;
Efferalgan Codeine¤; Efferalgan Vitamine C; Exidol¤; Febrectol-Tetracycline¤;
Febrectol¤; Febrispir¤; Fervex Rhume¤; Fervex; Gaosedal Codeine; Gelumaline¤;
Hexapneumine Compose¤; Humex etat Grippal; Humex Rhume; Humex¤; Hyrvalan¤;
Isofebril Vitamine C; Ixprim; Klipal Codeine¤; Klipal Codeine; Lamaline; Lindilane;
Mensuosedyl¤; Migralgine; NeoCitran¤; Novacetol; Panadol Codeine¤; Prontalgine;
Propofan¤; Rhinofeb¤; Rhinofebral; Rhumagrip; Rinurel¤; Rinutan¤; Salgydal a la
noramidopyrine¤; Sedarene¤; Sedigrippal a la vitamine C¤; Starem¤; Supadol¤;
Suppomaline¤; Theinol; Trophires Compose; Valda Rhinite¤; Valda Rhume¤;
Vegadeine¤; Veganine¤; Zaldiar; Germany: Alacetan¤; Algostadol N¤; Anti.opt¤;
Antigrippalin¤; Aplexil¤; ASS-Kombi¤; Azur compositum SC¤; Azur compositum; Azur;
Basoplex; Bersicaran N¤; Buscopan Plus; Cetebe antiGrippal; Chephapyrin N; Coffalon
N¤; Contac Erkaltungs-Trunk Forte¤; Contop¤; Contraneural N¤; Contraneural
Paracetamol/Codeine; Copyrkal; Ditonal N¤; Ditonal¤; Dolarist comp¤; Dolevar; DoloArthrosetten¤; Dolo-Neurobion forte¤; Dolo-Neurobion N¤; Dolomo TN; Dolopyrin;
Doregrippin; Ergo-Kranit¤; Ergo-Lonarid PD¤; Ergo-Lonarid¤; Eudorlin¤; Felsolyn N¤;
Fibrex Tabletten; Fineural N¤; Fohnetten N¤; Gelonida NA¤; Gelonida; Gentarol N¤;
Gentil¤; Gewodin¤; Grippal + C; Grippostad C; Grippostad Gute Nacht-Saft¤; HA-
Martindale: The Complete Drug Reference
Tabletten N; Herbin-Stodin¤; Husten- und Fieber-Saft¤; Hypertussin¤; Ilvico N¤;
Ingomidon N¤; Judolor comp. N¤; Kolton grippale N¤; Kontagripp-RR¤; Kontagripp¤;
Kreuz-Tabletten¤; Lonarid N¤; Lonarid¤; Malinert¤; Mandro-Gripp¤; Mandros-forte¤;
Melabon K; Melabon N¤; Mexe N¤; Migraeflux MCP; Migraeflux N¤; Migraeflux orange
N¤; Migralave + MCP; Migralave N¤; Migrane-Kranit Duo¤; Migrane-Kranit Kombi¤;
Migrane-Kranit N¤; Migrane-Neuridal; Migranerton; Monacant¤; Muskel Trancopal
compositum¤; Muskel Trancopal cum codeino¤; Mussera¤; Nedolon P; Neo-Gepan C¤;
Neo-Gepan¤; Neopyrin-N¤; Neopyrin; Nervinfant comp¤; Neuralgin; Neuramag P¤;
Neuranidal¤; Neuridal¤; Noflu F¤; Novo Petrin Novum; Octadon P; Octadon¤; Optipyrin;
Ozabran N¤; Ozothin¤; Paedisup¤; paracet comp¤; Paracetacod¤; Paracetamol comp;
Paracetamol plus¤; Paraflex spezial¤; Perdiphen-N¤; Perdiphen¤; Pilfor P¤; Praecimed
N¤; Prontopyrin plus; Quadronal comp¤; ratioGrippal + C¤; Ratiopyrin; Rio-Josipyrin
N¤; Saridon; Schworalgan¤; Siguran E plus¤; Siguran E retard¤; Siguran N¤; Silentan
spezial¤; Sinpro¤; Somnubene N¤; Spalt N¤; Spalt Schmerztabletten¤; Spasdilat N¤;
Spasmo-Bilgast¤; Spasmo-Gentarol N¤; Talvosilen; Thomapyrin Brausetabletten;
Thomapyrin C¤; Thomapyrin Medium; Thomapyrin; Tispol S¤; Titralgan; Titretta
Schmerz; Titretta Zapfchen; Toximer C¤; Toximer N¤; Toximer¤; Treupel comp¤;
Treupel-N¤; Trimedil N¤; Tylex¤; Ultrapyrin¤; Vivimed mit Coffein; Wick Daymed
Erkaltungs; Wick Daymed Erkaltungs; Wick Medinait fur die Nacht; Wick Medinait mit
Honig und Kamillenaroma; Zaldiar; Greece: Algine; Algon; Anadin Extra; Apotel C-500;
Apotel Extra; Buscopan Plus; Co-Depon; Comtrex Cold; Depon Extra; Depon Plus;
Depon Vit C; Junior Algon; Lonalgal; Lonarid N; Medamol; Norgesic; Panadol Cold & Flu;
Panadol Extra; Panadol Vitamin C; Parafon; Relacton-C¤; Relacton; Spasmo-Apotel;
Splentir; Toplexil; Hong Kong: America¤; Antamin¤; Anticol¤; Anticold; Antiflu Forte¤;
Antiflu-N-Forte¤; APA¤; Arfen Plus; Arthrodex¤; Beechams Hot Lemon¤; Children's
Coltalin Cold & Flu; Children's Tylenol Cold Plus Cough¤; Childrens Coltalin; Christamol
Extra¤; Christamol¤; Clariflu; Co-Fluenza¤; Colcap¤; Cold Medication Extra-Strength
Daytime¤; Cold Medication Extra-Strength Nightime¤; Coldcap-A; Coldrex¤; Coldtab-2;
Coldwafer¤; Coloft¤; Coltalin-GP Extra; Coltalin-GP; Coltalin-ND; Coltalin; Coritab;
Cosalgesic¤; Decolgen¤; Dexa-B¤; DF Multi-Symptom¤; Distalgesic¤; Ditonal¤; DoloNeurobion N¤; Dolocin; Dologesic¤; Dolpocetmol; Dristan Cold Maximum Strength¤;
Dristan Cold; Epizon¤; Extra Fast Coltalin Cold & Flu; F-Patarmol¤; F-Piridon¤;
Fastolin¤; Febricol; Flu-Off¤; Flu-Zep¤; Flucap¤; Flucor Day; Fludane¤; Fortolin Extra¤;
Fortolin Nite¤; Futalin¤; Futara¤; Hexapneumine¤; Koolnox¤; Lemsip Cold & Flu; Lemsip
Flu Strength¤; Lemsip¤; Logicin Flu Strength Day & Night; Logicin Flu Strength¤; Logicin
Martindale: The Complete Drug Reference
Hay Fever¤; Marflu-X¤; Mecostop¤; Medonol; Midrid¤; Myodrine¤; Neosed¤; Neozep;
Norgesic; Ornex¤; Panadeine; Panadol Cold & Cough; Panadol Cold & Flu Day; Panadol
Cold & Flu Extra; Panadol Cold & Flu Hot Remedy; Panadol Cold & Flu Nasal; Panadol
Cold & Flu Night; Panadol Cold & Flu Plus¤; Panadol Cold & Flu; Panadol Extra; Panadol
Menstrual; Panadol Sinus¤; Panadol Ultra; Paracetamol C & F¤; Paradrine; Paramol
Forte¤; Parasone¤; Parazone; Parcoten; Phenahist; Picapan; Pormus; Procetalette¤;
Procetamol¤; Propoxymol¤; Qualizep; Relaxin-P¤; Saridon¤; Sinutab¤; Snip¤; Tuseran;
Tylenol Cold¤; Ultracet; Uni-Proxamol¤; Unigan; Veganin¤; Vidatapp Forte¤; Virulex
Forte; Hungary: APC¤; Blackcurrant Coldrex Hot¤; Coldrex Junior; Coldrex Junior;
Coldrex MaxGrip; Coldrex; Coldrex; Efferalgan C¤; Fervex¤; Grippostad C; Lemon
Coldrex¤; Miralgin; Neo Citran; No-Spalgin; Novopyrin¤; Panadol Extra; Panadol Ultra;
Rhinoval C¤; Saridon; Scutamil C¤; Solpadeine¤; Talvosilen; Trinell Pro; ViCetamol¤;
Zaldiar; India: A'Cold; A'Cold; Abate-CZ; Abate; Abdal Plus; Abdal-SP; Abufen-C; AC
Para; AC-Plus; AC2; ACB Plus; ACB-S; Accept-P; Accept-SP; Accetiz-P; Ace-Proxyvon;
Ace-Q-Para; Ace-X; Aceact-P; Acebloc-P; Acec Plus; Acec-P; Aceclo Plus; Aceclo-MR;
Aceclo-Sera; Acecloren-P; Acecloren; Acedase-P; Acefen-P; Acefen-SP; Aceflow-P;
Aceforce-MR; Aceforce-P; Aceforce-SP; Acelofan Plus; Acelom-P; Acelom-SP; Acema-P;
Acemag-P; Acemiz-MR; Acemove Plus; Acemove-MR; Acemove-XT; Acenac-P; Acenec;
Acenez-P; Acent-MR; Acent-P; Acepar-MR; Acepar; Acepara-S; Acepara; Aceper; AcepilP; Acerap-P; Aceroc-P; Acetal-SP; Acetech-P; Acetonac; Acetrop; Acetuff-MR; AcetuffSP; Acewin; Aci-MR; Aciana-P; Acicloflex-MR; Acidol-P; Acifact-P; Acilex-P; Acimol-S;
Aciz Plus; Aciz-SP; Aclocta-P; Aclodase; Aclofen Plus; Aclog-CX; Aclog; Aclomp-P;
Aclomp-SP; Aclonac-P; Acloson-P; Acloson-SP; Aclozox; Acolate Plus; Acolate-P;
Acolate; Acolate; Acota-3; Acota-MR; Acticold; Actidol-DP; Actifed Plus; Actiflu Plus;
Actimol-F; Actimol; Actispas Plus; Actizobid; Actizox; Acudrin; Acuflu Plus; Acuflu;
Acuflu; Acuvin; Adcold-T; Adenim Plus; Adenim-MR; Adifax-P; Adifax-SP; Adiflam
Compound; Adiflam Plus; Adnac-MR; Adnim-P; Afen-P; Afesan-CZ; Afesan-P; AfesanSP; Agile-MR; Agile-S; Agile; Aglopam; Alcare-CC; Alco-P; Alco-PS; Alcofen; Aldee-P;
Aldidase-P; Alerid Cold; Aleron; Alex-P; Alex¤; Algin-P; Alice-D; Alicold; Alkasol-P;
Allset; Alnacer; Alnase-P; Alnase-SP; Aloo; Alora; Alostar-SP; Alsolide Plus; Alsolide-MR;
Altec-P; Alto P; Alto-3D; Altraflam-P; Amidase-DP; Anaflam; Anafortan; Anaida;
Anatram-P; Anbrol-A; Anbrol; Anim-P; Anm-P; Anodyne-P; Answell; Anthro; Anti-CC;
Anti-CC; Anticold; Apihist; Ara; Arcold; Arcure; Arflur-3D; Arflur-MR; Arflur-P; Argesic
Plus; Arid Plus; Arifnac-P; Arinox Plus; Aristopyrin; Armdic MR; Armdic Plus; Armix;
Arnim-P; Aroff Plus; Aroff-EZ; Arpa; Arrestadol-P; Arrestin-P; Arrestin-SP; Arsulide-P;
Martindale: The Complete Drug Reference
Arthorid; Artifen Plus; Artifen; Artigesic-MR; Artigesic; Aryl Plus; Aryl; Ascapar-P;
Asflam; Asicold Relief; Asicold; Asilid Relief; Asimol-AC; Asimol-DC; Asisneez; AsleraDP; Asolt-AT; Asolt; Asonac Forte; Asonac Plus; Asonac-SR Plus; Aspa Plus; Aspa;
Atcold; Atcold; Atdol Plus; Atofen Plus; Avdol-P; Avid Plus; Avifem-MR; Avifem; Avinim
Plus; Avisera Plus; Away-P; Axinim; Axsol-P; Azet Plus; Bactpar Plus; Balzox; Baselide;
Belrin-D; Belrin-D; Benim-P; Bestec; Bestofen; Bestoflame; Bestogesic MR; Bestogesic;
Bestonim P; Betaspasm Forte; Bidnac; Bio-Cold; Bionac-Forte; Biopar; Blast; BramadolP; Bren Plus; Brenlax; Brick; Brick; Briflam; Brontac-Plus; Bruace; Brucet; Brufamol-M;
Brufamol; Brupal; Brustin; Brutek-P; Bufex Kid; Bufex Plus; Bufex-C; Bufex-CD; ButaM; Butacort-DP; Butaproxyvon; Buwin Plus; C-Cold; C-Gesic; C-MR; C-Nac; C-Nim Plus;
Cadiflam-NP; Cadiflam; Cadol-P; Cafepar; Calmcold; Calmcold; Calpol Plus; Calscot;
Calscot; Campar; Canefo-Plus; Canmet-P; Carecof Exp; Carecof; Carisoma Compound;
Carnil ACP; Carnil Plus; Casdom-P; Caslide-P; Catrix-P; CCFS; CCGO; Cebrine Plus;
Ceco Plus; Ceco-SP; Ceedokid Plus; Ceflame; Ceklif Plus; Celfast Plus; Celfast;
Centrivon; Centwin; Cep-DP; Cep-MR; Ceralide-P; Cetcip Cold; Cetin Cold; Cetin Plus;
Cetra; Cezcold; Cheston Cold; Cheston Cold; Chlorizok; Cinaryl; Cincam-P; Cipgesic
Plus; Cipladon; Cipzox; Ciz Cold; Clobee-SP; Clofen-SP; Clomet-P; Clonac Plus; ClonacSP; Clopar MR; Clopar Plus; Clopar-K; Clophen-P; Codomolindon; Codoplus; Codopyrin;
Codylex Plus; Codylex-CC; Codylex-DMR; Cof Q; Cofdex CC; Cofenac; Cofev; Colarest;
Cold Calm; Cold-CZ; Cold-Relief; Cold-War; Coldact Plus; Coldant; Coldap; Coldarest;
Coldargic; Coldargic; Coldargic; Coldastat-LX; Coldastat; Coldastat; Coldcure; Coldec;
Coldeez; Coldfree; Coldgone; Coldilak; Coldoff; Coldrest; Coldrest; Coldrif; Coldtaur;
Coldtaur; Coldwar; Coldwar; Coldy; Coldy; Colep; Colgin; Colgin; Colicspam; Colidex;
Colimef; Colimex; Colirid; Colispas; Colixin MPS; Colpep; Colpep; Colrex Plus; Colsan;
Combiflam; Combigesic-DP; Combihext; Combinac-MR; Combinac; Combit; Combodol;
Conac-P; Conac-PT; Congestyl; Congestyl; Control; Contus Plus; Contus-650; Copar;
Cor-4; Cor-4; Cor-4; Cor-CC; Corbutyl; Coriko-P; Coriminic Plus; Corinite; Corinite;
Cosavil¤; Coscold; Covil-A; Cozine; Cozy Kid; Cozy Plus; Cozymin; Cozymin; Cozymin;
CPP; Cradol-P; Cranim-P; Crocin Cold N Flu; Crocin Pain Relief; Crophen; Crozy Plus;
Cudom-P; Cuffmol-P; Cuga Plus; Cunim Plus; Cuzox-MR; Cyclo-P; Cyclopam Plus;
Cyclopam; Cyclowin; Cyclozed; Cyka Plus; Cynac-MR; Cynac-P; Cynac-SP; Cypa;
Cytodec Forte; CZ-Cold; Dacnis N; Dacpar; Dacron-Plus; Dardnil-P; Dart; Darvocet;
Daze-DP; Dazina-DP; DCol-BR; Decil; Decizox; Decold Plus; Decolgen Day & Night;
Decolgen-P; Decomb; Decotram-PD; Defenac-P; Delcon Plus; Delfina Plus; Delnim-P;
Delnim-SP; Delock-MR; Demo-MR; Demo-P; Demo-SP; Demol; Dencold; Dencold;
Martindale: The Complete Drug Reference
Denim P; Denim Plus; Dentain; Dersy-AP; Devona Plus; Dexia; Dexigesic-P; Dexovon;
Diazox-MR; Diazox; DIC-550; Diciosis; Dicloact Plus; Dicloat Plus; Dicloat-CZ; Diclobit;
Diclofalm Forte; Diclofam Plus; Diclofast-P; Dicloflam MR; Dicloflam P; Dicloflam Plus;
Diclogen Plus; Diclogesic Spas; Diclogesic; Diclohill-P; Diclolab Plus; Diclomol;
Diclomove-MR; Diclomove-P; Diclonac-MR; Diclonac-P; Diclonet-Forte; Diclonij-KMR;
Diclonij-KP; Diclonij-Super; Diclonova MR; Diclonova P; Diclopep Plus; Dicloran-A;
Dicloriz; Diclosar-P; Diclosim; Diclosym; Diclotab; Diclotal Forte; Diclotop; Diclovar-CZ;
Diclovar-Plus; Diclowin Plus; Diclozed-Plus; Dicnac MR; Dicnac Plus; Dicnac-P; DicnacxP; Dicnacx-SP; Dicnap-MR; Dicnap; Dico P; Dicol-MR; Dicol-Plus; Dicoliv Plus; DicolivMR; Dicomin; Dicron Plus; Dicron-C; Diculone; Dicven Plus; Dicyclome-P; Dicyclozed;
Diczone Plus; Diczone-MR; Didol-D; Didol-P; Difenac Plus; Difin Plus; Difisal Plus; Diflac
Plus; Diike; Dikpa; Dikul MR; Dikul P; Dilofen-CZ; Dilofen-MR; Dilofen-P; Dilona Plus;
Dilophen-SP; Dinal-AP; Dion MR; Dion-P; Dipal-F; Dipclo-MR; Diplofen 3D; Diplofen-MR;
Diplofen-P; Diplonim; Dipt-P; Divexx-MR; Divexx-P; Divon Plus; Dixfree-SP; Dizox; DMP
Plus; Dodo-MR; Dodo; Doflex Plus; Dolact; Dolamide; Dold; Dolfen-P; Dolide Plus; DoloCold; Dolobak; Doloban; Dolocet; Dolochek-P; Dolocide KP; Dolocide MR; Dolocold;
Dolocrat; Dolofenac; Doloflam Plus; Dolokind Plus; Dolokind-AA; Dolokind-MR;
Dolomed-MR; Dolomed; Doloral P; Doloroff-AP; Doloroff-ASP; Dolostat-MR; Dolostat-PC;
Dolour-X; Dolowin Forte; Dolowin Plus; Dolowin-MR; Dolozox; Dols Plus; Dolwin-T;
Dolwin; Dom-P; Domac; Domact-P; Domadol Plus; Domcet; Domden-P; Domkair-P;
Dompar; Domperon Plus; Dompon P; Domspas; Domstal-P; Don-MR; Don; Dordase-DP;
Doset Plus; DP Gesic MR; DP Gesic; Dpazox; Dr Smyle; Dristan Cold¤; Dropar; Drotin
Plus; DSP; DSQ; DT-Ibuflam; Dual Cold; Dual Gesic Plus; Dual Gesic; Dualflam;
Dublace-P; Dublace-SP; Dublact; Duodil; Duoflam Plus; Duoflam; DVN-Forte; Dynapar
LD; Dynapar; Dysmen Forte; Dysmeryl; E-Cold; E-Dol Plus; E-Fen-CZ; E-Fen; E-Nim
Plus; Easicold; Ebility; Eclo-P; Eclonac-P; Ecnac-P; Egrin; Elaxic-P; Elaxic; Elcold-DS;
Elcold; Eldom-P; Elfenac Plus; Elfenac-MR; Elgnil Cold; Elven-P; Emanzen-DP; Emflam
Plus; Emispan Plus; Emispan-H; Emsulide-P; Encold-P; Encold-P; Endospas; Enzoflam;
Erinac-P; Esgipyrin-T; Esgipyrin; Essmol-3 Plus; Essmol-AF; Etolex-P; Etolor-P; EtomaxP; Etova-P; Etric Plus; Etro-P; Eudase-DP; Evercold; Expergesic; Extranac; Fan-P;
Fastnac; Febrex Plus DS; Febrex Plus; Febrex Plus; Febrinil-P; Fedol; Fenac-P; Fenace
Plus; Fenadec MR; Fenadec Plus; Fenaplus-MR¤; Fenaplus¤; Fenbest MR; Fenbest P;
Fenbest Plus; Fenceta; Fendic Plus; Fensaide-P; Fentra; Fentrex; Fenzone Forte;
Fenzoxe Forte; Fepra-P; Festa; Fevacold; Fevastin Plus; Fevni-P; Fevomax; Fevril;
Fevril; Ficlo-P; Fico-P; Fico-SP; Fincof; Fineorest; Fitflam; Flamace-MR; Flamace-P;
Martindale: The Complete Drug Reference
Flamace-SP; Flamar-DP; Flamar-MX; Flamar-P; Flamese-K; Flamese-KR; Flamtop;
Flanzen-DP; Flaxinac-SP; Flaxinac; Flexicam; Flexidol-P; Flexigesic-MR; Flexigesic;
Flexinol; Flexon-MR; Flexon; Flozen Plus; Flozen-AA; Flu-4-BR; Flu-4-XN; Flu-4; Flu-4;
Flu-4; Flucold; Flukuff; Flupara-N; Flupara-SN; Flurid; Fluzet; Fluzet; Fonim-P; Foracet;
Forcol-D; Forgesic-MR; Forgesic-SP; Fornac-CZ; Fornac-P; Fornac-SP; Fortafen Plus;
Fortagesic; Freedom Forte; Frenac Plus; Frenac-MR; Freze; Fricold; Fricold; Frispas-P;
FS Plus; FS-D; Gag-PR; Gefplus; Genac-SP; Genlide Plus; Gesnac-P; Gesnim-P; Ghoom;
Gic-SR; Gocold; Gramol-P; Gramol-SP; Gredol; Grenil; GS-AP; GSNim-P; Haloran Plus;
Hatric-3; Hidiclo Plus; Hidiclo; Hifenac-D; Hifenac-MR; Hifenac-P; Hilyte-P; Hitz-NP;
Hyvon-Spas; Iben Forte; Iben Plus; Ibubid Plus; Ibucet; Ibuclin; Ibucon Plus; Ibudol-A
Kid; Ibuflamar-P; Ibugesic Plus-NF; Ibugesic Plus; Ibumac Plus; Ibumax; Ibumet P;
Ibumol; Ibun; Ibunij; Ibupar-M; Ibura; Iburic Plus; Ibuspan-P; Ibutop; Ibuwin; IcenacP; Icobit-P; Icobit-Plus; Icparil; Idalez Plus; Ifycet; Imflamol-C; Imflamol-ZX; Imol Plus;
Imol; Imosan; Imsimol; Inac-P; Inane-P; Incold; Incold; Indlide; Indofenac-P;
Indolpara; Inflahit-P; Inflahit-SP; Inflameri; Inflaryl-AD; Ingahist; Ingesic Forte;
Ingesic-MR; Ingesic-P; Inmecin-P; Inslide; Instaryl-Cold; Instaryl-Cold; Intagesic-MR;
Intagesic; Intenoal; Intragesic-MR; Intragesic; Ipecee; IPM; Isiko-Plus; Jacpar; JagrilSpas; Jiffy; Jonac Plus; Jumo; Jumocip; Jusgo-MR; Kairnac-P; Kamadol-P; Kaylid-P;
Kazicold; Kdol-P; Kelvin Plus; Kelvin-P; Kevtram-DP; Kevtram-P; Khalli; Kidcet-Cold;
Kind Plus; Kinectine P; Kinectine-MR¤; Kineto DP; Klonac-P; Klonac-XS; KMR; Kno-OL;
Kol-DC; Kold Time; Kolderon; Koldy; Kolq; Kolq; Kozifed; Kudzu; Kuff-Q; Kufkair-P;
Kufkair-P; Kurdase Plus; L-Cit Plus; L-Triz Plus; Labace-P; Labdic Relief; Labocof;
Lacfen-P; Ladex-P; Larigox; LCN-Plus; LCZ-Plus; Lebec-MR; Lebec-NP; Lecerein-P;
Leday-CC; Lederflam Plus; Leebec-NP; Leedol-P; Lemo Linctus; Lemo-P; Lemohist-C;
Lemohist; Lemohist; Lenagesic; Lenex; Lenomol; Lenor-P; Leofenac-MR; Leofenac-SP;
Leverest Plus; Levogo Plus; Levoriz Plus; Levostar Plus; Levotrin-P; Lezdes-P; Lezine-P;
LG Plus; LG-Plus; Lipcy-A; Lipcy-MR; Litnim; Litonac-MR; Litonac-P; Litonac-SP; Lobak;
Locet-P; Lofen; Lolira-P; Loni-Plus; Lorbit-P; Lorchek-P; Lorflam-P; Lormoto-P;
Lornistar-P; Lornofan-P; Lornoxi-P; Lorsaid-P; Lorter-P; Lorthox-P; Lorup Plus; LorwalkP; Lowdol; Loxcam-P; Loxicam-P; Lucold; Luloxy-P; Lupiflam-C; Lupiflam; Lupisetron
Plus; Lupisulide MR; Lupisulide-P; Lupivon-D; Lupivon; Lyser-DP; Lysoflam; Madol-P;
Magadol-SP; Magadol; Magadol; Mahadol; Mahanac Pro; Marcold; Marcold; MaxigesicMR; Maxigesic; Maxinac; Maxofen; Maxoflam-A; Maxoflam-D; Maxoflam-MR; MaxoflamT; Maxoflam; Maxonim-P; Maxrel; Maxtra-P; MDace-P; MDace-SP; Medinac; Medler;
Mefacid Forte; Mefar-PD; Mefegesic; Meflup Forte; Mefsym-Plus; Meftagesic; Meftagesic;
Martindale: The Complete Drug Reference
Meftal Forte; Melodol; Mepar; Meridol-D; Meridol; Meriflam; Mesu-P; Metoclop-P;
Metogin; Metopar; Metpar; Mezonac; Microdase-DP; Micronac Plus; Micronac-MR;
Migranil; Minidolo; Minipar-P; Minipar-SP; Minsu-P; Miradol; Mizeco; Mobifen; Mobiflam;
Mobinorm; Mobisox; Mobitone; Mobizox; Mofax; Molide; Molsee; Molulid; Morcet Plus;
Morcet-MR; Morcet; Mortrin Compound; Motinorm-P; Motion Plus; Movace Plus; Movelite
Plus; Mover; Movex-SP; Movexx Plus; Movilor-P; Movinim-P; Moviz XP; Moviz-3D;
Movon-MR; Movon-P; Movon-PT; Mucoresp-3D; Mucoresp-CT; Mumo; Muscodac;
Muskel; Mydic-MR; Mydic-S; Mygran; Myofan; Myospaz Forte; Myospaz; N-Pain Relief;
N-Plus; N-S-Plus; Nac Plus; Nacku-P; Naclomol-MR; Naclomol-S; Naclomol; Nacpo;
Naid-P; Nal-PM; Naldecon; Nam Cold-Z; Nam Cold; Nam-P; Nap Plus; Nasocare Plus;
Nasocare Plus; Nasoryl; Natcold Plus; NBLcet Plus; Need; Neet Plus; Neflo-P; Nefter;
Nelsid Fort; Nelsid Plus; Nemeriv-P; Nency-P; Neofebrin; Neosulide Plus; Nepar;
Neucam-P; Neulab Active; Neuromol-MR; Neuromol; Neurophen; Neurospas; Neurovon;
Neurozine; Neutram-P; Nevis-P; New Artifen Plus; New Mezonac; Nextcam-P; Niap;
Nicet; Niciflex-T; Nicip MR; Nicip Plus; Niclopar-S; Nictram Plus; Nifen MR; Nifen Plus;
Nifen; Nile Plus; Nile-CZ; Nile-P; Nile-SP; Nilup-P; Nimace-P; Nimagyl-PC; Nimaid-P;
Nimat-Plus; Nimbra Plus; Nimbus Plus; Nimcare-A; Nimcet Plus; Nimcin-P; Nimdard
Plus; Nimdase-P; Nimeb-P; Nimegesic-P; Nimesel-P; Nimesis-P; Nimeter-A; Nimica Plus;
Nimiz-Plus; Nimkair-F; Nimkair-P; Nimkul Para; Nimkul-MR; Nimlak-Plus; Nimley-P;
Nimli-P; Nimlid-P; Nimnil-P; Nimodex; Nimodia-P; Nimofen-P; Nimopace A; Nimopace;
Nimotas-P; Nimoven; Nimpa; Nimpain P; Nimpain PS; Nimpar; Nimpara; Nimpure-P;
Nimpure-PS; Nimriz Plus; Nims-P; Nimsaid-P; Nimsol Plus; Nimucare-P; Nimucet-MR;
Nimucet; Nimuflex-MR; Nimuflex-P; Nimuflex; Nimumol-P; Nimupain Plus; Nimuris-Plus;
Nimustar-P; Nimusym-Plus; Nimutal-Plus; Nimvar Plus; Nimven Plus; Nimvista Plus;
Nimvista-MR; Niplonac-MR; Niplonac-P; Nisba Plus; Nismol-S; Nismol; Nizapas-P; Nizla
Plus; Noalzy Plus; Nobel Plus; Nobel-MR; Nocold Plus; Nocold Plus; Nocold; Nodard Plus;
Noflam P; Nom-P; Normal; Norpy; Nosirid-P; Novadol-P; Novil; Novo-Plus; Novodase;
Novodex; Novodol; Novoflam-Plus; Novonac-P; Novozox; Noxi-P; Nozee; Nozee; NozikP; NP.Com; NPM; NT-Spas; Nucez Plus; Nucez Plus; Nucold; Nucold; Nucoxia-P;
Nugesia; Numol-MR; Numol; Nupar; Nuren-Ace; Nuroflow; Nusaid-MR; Nusaid-P;
Nusaid-SP; Okanorm Plus; Omodol; Onafen-CZ; Onafen; Ontact Forte; Opel Plus; OpiOT; Opiate-P; Opiate-PD; Optiflam-P; Orilox-P; Oronac Plus; Orphamol; Orthodac MR;
Orthodac; Orthodex; Osdip-MR; Osdip; Oshdol; Osnip; Osonim-P; Ospidyne; Osteodol;
Osteoflam-MR; Ostizox; Osyfen Plus; Osynec-K; Otonac-P; Otram; Oxalgin-DP; Oxokool
Plus; Oxybuta; Oxymark; Oxynal-P; Oxypamol-D; Oxyprem; Pacidom-P; Pacimol Plus;
Martindale: The Complete Drug Reference
Pacimol-M; Pacinac; Pacinac; Pacizox; Paclo-MR; Painadol-P; Painkair-MR; Painkair; PalMF; Pamagin C; Pamagin C; Pamagin Plus; Pamela; Pamol DCM; Panace-P; Panama
Plus; Panama-D; Panama-SP; Panum-P; Paracip CPM; Paracip Plus; Paraclo; Paracod;
Paracodrate; Paradic-C; Paradic-MR; Paradic; Parafon; Parafortan; Paral-P; Paraldim;
Paralide; Paramet; Paranorm; Parasafe; Paratel Plus; Paratel-AC; Paratel-ACP; ParatelDS; Paratel-LC; Paratel-NP; Paratel-T; Parazobid; Parazolandin; Parazox-D; Parclo-AP;
Parvon Spas; Parvon-N; Parvon; Proxytab; Proxyvon; Ralcidin; Reactine Forte; Reactine
Plus; Reducin-A; Relaxyl Plus; Rinostat; Robinaxol; Rofecip Plus¤; Salyzine¤; Sinarest;
Sinarest; Sinarest; Spasmo-Flexon; Spasmo-Proxyvon; Spasmocip Plus; Spasmocip;
Spasmonil Forte; Spasmonil; Sudhinol; T-Minic Plus; Tolydol; Tramacip Plus; Triaminic¤;
Trigan-D; Ultrazac; Vectra-P; Walagesic; Wygesic; Zerodol-MR; Zerodol-P; Zimalgin;
Indonesia: Abajos; Actigesic¤; Agrippin¤; Aknil¤; Alpara; Anacetine; Anadex; Antiza;
Arthrifen Plus; Axalan¤; Bestocol; Bisolvon Flu; Bodrex Extra; Bodrex Flu & Batuk
Berdahak; Bodrex Flu & Batuk; Bodrex Flu & Batuk; Bodrex Migra; Bodrex; Bodrexin Flu
& Batuk; Bodrexin; Bronchitin; Buscopan Plus; Bycolen; Calorex¤; Coditam; Cold Cap;
Colfin; Colpica; Colza¤; Combi Flu; Contrex; Corexin¤; Corhinza; Corsagrip; Decolgen;
Decolgen; Decolsin; Deconal; Dextrosin Anak; Dolo-Neurobion; Dorbigot; Extra-Flu;
Farapon; Febrinex; Feminax¤; Flu Stop; Flu-Tab; Flucadex¤; Flucodin; Flucyl¤; Fludane
Plus; Fludane; Fludexin; Flugesic; Flunadin¤; Flunax¤; Flurin Dmp; Flurin; Flutamol-P;
Flutamol; Fluzep; Fortaflu¤; Frigrip; Gitas Plus; Gunacold¤; Head-O; Hustab; Intunal;
Inza¤; Iremax; Kafsir; Kidikol; Kontrabat; Lacoldin; Limasip¤; Lodecon; Migran¤;
Mixaflu; Mixagrip; Molexflu; Nasafed Plus¤; Neladryl DMP¤; Neo Novapon Plus; Neo
Novapon; Neo Rheumacyl; Neozep; Neuralgin; New Coldin¤; Nipe; Nodrof; Nogren;
Oskadon Flu & Batuk Berdahak; Oskadon Migra; Oskadon SP; Oskadon; Paramex¤;
Paranomin; Paratusin; Paratusin; Patral; Pilexal; Poldan; Ponflu; Primadol; Procold;
Profenal; Recomint; Refagan; Sanaflu Plus; Sanaflu; Saridon; Scopamin Plus; Scopma
Plus; Shelrod-Plus¤; Silabat¤; Sistenol; Somadril Compound; Spashi Plus; Spasmacine;
Stop Cold; Supra Flu; Termorex Plus¤; Thymcal; Topras; Trifedrin Plus; Tuseran Forte¤;
Tuzalos; Ultracet; Ultragrip¤; Ultragrip; Ye & To; Zaldiar; Ireland: Anadin Extra;
Beechams Cold Relief¤; Beechams Flu-Plus; Beechams Hot Lemon Decongestant¤;
Beechams Hot Remedies¤; Benylin 4 Flu; Benylin Day & Night; Coldrex¤; Cosalgesic¤;
Day & Night¤; Day Nurse; Disprin Extra¤; Distalgesic¤; Dozol; Feminax; Fortagesic¤;
Hedex Extra; Ilvico; Ixprim; Kapake; Lemsip Cold & Flu With Caffeine; Lemsip Cold &
Flu; Lemsip Cough & Cold with Caffeine; Lemsip Max Cough & Cold; Lemsip Max Relief
Capsules¤; Lemsip Max Sinus & Flu; Lemsip Pharmacy Flu Strength¤; Lemsip Pharmacy
Martindale: The Complete Drug Reference
with Phenylephrine¤; Lemsip Sinus; Lobak¤; Maxilief; Migraleve; Mu-Cron¤; Night
Nurse; Nirolex Day Cold & Flu; Non-Drowsy Sinutab; Norgesic¤; Panadeine; Panadol
Cold & Flu Relief; Panadol Cold & Flu; Panadol Extra; Panadol Fever & Congestion;
Panadol Head Cold; Panadol Max Strength Cold & Flu; Panadol Night; Paracodol¤;
Parahypon¤; Paramax; Paramol; ParaPlus; Resolve; Rowacylat¤; Sinutab; Solpa-Flu;
Solpa-Sinus; Solpadeine Cold & Flu; Solpadeine; Solpadol; Syndol; Teedex; Tramil;
Triogesic¤; Tylex; Uniflu & Gregovite C¤; Uniflu Plus with Vitamin C; Uniflu with Vitamin
C; Veganin Plus; Veganin¤; Vivimed¤; Israel: Acamol Focus; Acamol Night; Acamol
Orange; Acamol Tsinun & Shapa'at Day; Acamol Tsinun & Shapa'at Night; Acamol
Tsinun Day; Acamol Tsinun Night; Acamoli Cold; Alcinal Plus¤; Algolysin; Beechams
Remedy¤; Broncholate Plus; Cod-Acamol; Codabrol; Codisal Forte¤; Coldex; Dexamol
Cold Day; Dexamol Cold Night; Dexamol Plus; Dexamol PM; Dexamol Sinus Day;
Dexamol Sinus Night; Efferalgan Codeine¤; Excedrin; Exidol; Migraleve; Muscol;
Norgesic¤; Novimol Tsinun; Novocalm¤; Pacetal¤; Paracod¤; Paramol AF and Shiul Day;
Paramol AF and Shiul Night; Paramol AF Day; Paramol AF Night; Paramol Plus; Percocet;
Proxol; Rogaan; Rokacet Plus; Rokacet; Rokamol Plus Codeine¤; Sinusal¤; Spasmalgin;
TheraFlu Colds & Flu; Triaminic Cold, Cough & Fever¤; Tricold¤; Zaldiar; Italy: Actidue;
Actigrip; Algopirina; Alsogil¤; Anticorizza¤; Antiflu¤; Antinevralgico Dr Knapp¤;
Antinevralgico Penegal¤; Antireumina; Baby-Rinolo; Benylin Day & Night¤; Bronchenolo
Antiflu¤; Bronconait¤; Buscopan Compositum; Calmante Murri¤; Cebion Febre e Dolore;
Cletanol C¤; Cletanol¤; Co-Efferalagan; Codamol; Contralgen¤; Decongene¤; Depalgos;
Doloflex¤; Dolvis¤; Drin¤; Efferalgan C; Euci¤; Femidol¤; Fepramol¤; Fluental;
Fluvaleas¤; Honeycold¤; Honeyflu¤; Influmed C; Influmed; Influrem¤; Influvit; Iodosan
Raffreddore Contac¤; Kolibri; Lasafort¤; Lisoflu; Lonarid; Micranet¤; Murri
Antidolorifico¤; Neo Nisidina C-Fher¤; Neo Nisidina; Neo Uniplus C¤; Neo Uniplus¤; NeoCibalgina; Neo-Nevral; Neo-Optalidon; Neodone¤; Odontalgico Dr. Knapp; Omniadol¤;
Parinvenza; Patrol; Raffreddoremed; Rectocoricidin¤; Saridon senza Caffeina¤; Saridon;
Sinegrip; Tachicaf; Tachidol; Tachiflu¤; Tachifludec; Tachinotte; Triaminic Flu; Triaminic;
Triplice¤; Veramon; Verdal¤; Vicks Medinait; Vitialgin¤; Zerinetta-Fher¤; Zerinetta;
Zerinoflu; Zerinol; Japan: Sin Colgen Kowa Kaze¤; Tramcet; Malaysia: Anarex;
Cetagesic; Cheri 4 Flu; Chlornamol¤; Decolgen; Dihydrocodeine P; Febricol; Flucor Day;
Flucor Night; Norgesic; Orphenadol; Pabron Cold & Flu¤; Pabron Cough & Aches;
Panadeine; Panadol Cold Flu; Panadol Cold; Panadol Menstrual; Paracetamol C & F¤;
Paracetamol Plus¤; Paragesic; Parakol; Paras; Sinuzin¤; Suniton¤; Ultracet; Uphamol
Flu; Uphamol Plus Codeine; Zainexpect C & F¤; Mexico: Actifed Dia Advance; Actifed
Martindale: The Complete Drug Reference
Dia¤; Actifed Noche Advance; Actifed Noche¤; Acxen¤; Agrifen T; Agrifen; Algitrin;
Analgen Forte; Antiflu-Des; Arsenal Compuesto; Arxen Compositum; Asafen¤; Biasquin
F; Bifardol; Bifebral; Bioflusin; Brax; Breaflu; Brefar; Bregamin FC; Bregamin;
Bremagan Flu; Bremol; Buscapina Compositum N; Calgayan; Cantipal¤; Carbafen; CK2; Clariflu; Clarifriol; Clorfriol¤; Cloten; Co-Exaliv; Co-Tylenol; Coldaid; Contac AM¤;
Contac C; Contac PM¤; Contac Ultra¤; Coricidin F; Coricidin Pediatrico NF¤; Corilin F¤;
Cortafrin; Cotofin¤; Cripofen; Cripofen; Dafloxen-F; Decosil; Deflamox Plus; DesenfriolIto Plus; Dolotandax; Drunen; Dualgos; Escapin-N; Exalver G; Exalver; Exortin; Farxen;
Febrax; Femsedin Kutz; Fiverdol; Flavit AV; Flaxenol; Flepin X-3¤; Flumejoralito Gripe¤;
Flunadrina; Fluviatol NF; Fluviatol; Friobax; Gripson; Histiacil Flu; Histiacil T; Histiacil
Tex¤; Infafren Compuesto¤; K-Y-6; Kensedal; Laritol G; LM6; LM6; Masferol; Medin G¤;
Megal; Mejoral Plus; Movex; Mydocalm-A; Naprodil Plus¤; Nedoxal; Neo-Percodan;
Neorpan Plus; Nocsin PM¤; Norflex Plus; Numonyl C¤; Numonyl T¤; Numonyl Tex¤;
Onexmol; Parafon Forte; Parsel; Pensodil; Pirafrin; Piralgina C; Piralgina; Plexicodim;
Polet; Precicol; Pron-X; Proxalin Plus; Qual; Quimofeina; Raxenol; Reucortil; Rinofren
Pediatrico; Rinofren; Robaxifen; Rosel; Saridon¤; Sedalmerck Flu; Sedalmerck TH¤;
Sedalmerck; Sedalmerck; Selpiran Compuesto; Senidrin; Senidrin; Sensibit D-NF;
Sensibit D; Sin-A Crud¤; Sindo; Singrilen; Sinutab Extra; Sudis; Superal Ex¤; Superal¤;
Syncol Nocturno; Tafirol AC; Tafirol Flex; Taxenan¤; Tempra CD¤; Tempra MF¤;
TheraFlu CM; TheraFlu CN; TheraFlu Ex; TheraFlu TD; TheraFlu; Tramacet; Tusilen
Pediatrico; Tylenol Sinus; Tylex CD; Tylex Flu; Ulpafie Compuesto¤; Ulpafie-N; Velsay-S
Compuesto; Viladol Plus; Viplus; Vitanumonyl C¤; Xenorac's; Zaldiar; Netherlands:
Afluvit¤; Antigrippine Hot Drink¤; Antigrippine; APAC¤; APC; Chefarine¤; Citrosan; Daro
APC; Daro Hoofdpijnpoeders; Excedrin; Femerital¤; Finimal C; Finimal; Hot Coldrex;
Kruidvat APC; Kruidvat PPC; Kruidvat; Panadol Plus; Para-don; Paracetamol comp;
Paracof; Propyfenazon comp; Roter APC; Sanalgin; Saridon; Solpadol¤; Spalt N¤;
Tilalgin¤; Tramacet; Trekpleister APC; Witte Kruis; Zaldiar; Norway: Aporex¤; Lobac¤;
Norgesic¤; Paralgin; Pinex Forte; Pinex Major; Somadril Comp¤; New Zealand: ApoParadex¤; Benylin Cold¤; Capadex¤; Codral 4 Flu¤; Codral Cold & Flu¤; Codral Cough,
Cold & Flu Day & Night¤; Codral Daytime/Nightime¤; Codral Pain Relief¤; Coldrex
Day/Night¤; Coldrex Flu¤; Coldrex Head & Chest Cold¤; Coldrex Head Cold¤; Coldrex
Night Relief¤; Day & Night Cold & Flu¤; Di-Gesic¤; Dimetapp Cold & Flu¤; Dimetapp
Cold, Cough & Flu Day & Night¤; Lemsip Cold & Flu Headcold; Lemsip Flu Strength;
Lemsip Max Day & Night¤; Maxigesic; Mersyndol; Norgesic; Orthoxicol Cold & Flu¤;
Orthoxicol Day & Night¤; Panadeine¤; Panadol Night; Paracode; Paradex¤; Paramax;
Martindale: The Complete Drug Reference
Pharmacist's Own Pain Relief Plus; Pharmacist's Own Pain Relief; Pirophen; Pryndette¤;
Sinutab Sinus & Pain Relief¤; Sinutab Sinus Allergy & Pain Relief¤; Sudafed
Day/Nightime Relief¤; Sudafed PE Sinus and Allergy and Pain Relief; Sudafed PE Sinus
and Pain Relief; Sudafed PE Sinus Day and Night Relief; Sudafed Sinus Pain & Allergy
Relief¤; Sudafed Sinus Pain Relief¤; Philippines: A-P-Histallin¤; Alaxan; Algesia;
Analem; Anoflam; Bioflu; Brustan¤; Buscopan Plus; Cetodol; Cetra; Coldzep; Colvan;
Congestril (Reformulated); Cynosal; Decolgen Forte; Decolgen No-Drowse; Decolsin
Reformulated; Dolcet; Dolo-Neurobion; Drinus; Dynatussin; Fladexon; Flexan;
Flexigesic; Flucor Day; I-Laxx; Insomed; Isoflu (Combipack); Mucotuss; Muskelax;
Myracof-T¤; Nafarin A (Reformulated); Nagelin; Nasagesic; Nasathera; Neo-Bromexan
Forte; Neozep Non-Drowsy; Neozep; Norgesic; Ornex; Parafon¤; Proflex; Relievo;
Restolax; Selxan; Sinutab Extra Strength; Sinutab PE; Tusedex; Tuseran Forte; Unigan;
Poland: ActiFlu Extra C; Acutral; Analget¤; Antidol; Apap C Plus; Apap Extra; Apap
Noc; Apap Przeziebienie Extra Plus; Cefalgin; Codipar Plus¤; Coldrex HotRem; Coldrex
MaxGrip C; Coldrex MaxGrip; Dafalgan Codeine; Dolores¤; Doreta; Efferalgan Codeine;
Efferalgan Vitamin C; Febrisan; Fervex; Flucontrol Hot; Gripex Control; Gripex HotActiv;
Gripex Noc; Gripex V; Gripex; Grippokaps; Grippostad C; Grypolek; Grypostop Mix;
Grypostop; Kofepar¤; MaxFlu; Metafen; Neopyrin ASA; Pabitan; Padolten; Panadol
Extra; Panpiryna; Poltram Combo; Pro-Miss; Saridon; Solpadeine; Tabcin Impakt;
Tabcin Trend; Talvosilen; Theraflu ExtraGRIP; Theraflu Zatoki; Ultracod; Vegantalgin H;
Vicks Active Complete; Zaldiar; Portugal: Adalgur N; Afebryl; Algifene; Algik;
Almigripe; Anadin Extra¤; Anti-Gripe¤; Antigrippine; Bisolgrip T¤; Buscopan
Compositum N; Casfen¤; Cegripe; Coricidil-D¤; Dafalgan Codeina¤; Dol-u-ron;
Fludeten¤; Gripidor; Griponal; Ilvico N; Migraleve; Migretil; Norgesic¤; Panadol Extra;
Panadol Sinus; Paramolan C; Saridon N; Sinutab II; Tilalgin; Ugrilon¤; Veganine¤;
Zaldiar; Russia: Algofetin (Альгофетин); Anacold (Анаколд); Antiflu (Антифлу);
Antigrippin (Антигриппин); Antigrippin-Maximum (Антигриппин-Максимум);
Antigrippin-Maximum (Антигриппин-Максимум); Apap C Plus (Апап С Плюс);
Aquacitramon (Аквацитрамон); Ascophen-P (Аскофен-П); Brustan (Брустан); Caffetin
(Каффетин); Caffetin Cold (Каффетин Колд); Citramon P (Цитрамон П); CitramonBorimed (Цитрамон-Боримед); Citramon-MPF (Цитрамон-МФФ); Citrapak (Цитрапак);
Codelmicst (Коделмикст); Coffedon (Коффедон)¤; Coficil-Plus (Кофицил-Плюс);
Coldact Flu Plus (Колдакт Флю Плюс); Coldfri (Колдфри); Coldrex (Колдрекс); Coldrex
HotRem (Колдрекс ХотРем); Coldrex Junior (Колдрекс Юниор); Coldrex MaxGrip
(Колдрекс МаксГрип); Coldrex Nite (Колдрекс Найт); Daleron C (Далерон C); Dolaren
Martindale: The Complete Drug Reference
(Доларен); Efferalgan with Vitamin C (Эффералган с витамином C); Fastoric Plus
(Фасторик Плюс); Febricet (Фебрицет); Femizol (Фемизол); Fervex (Фервекс);
Flucoldex (Флюколдекс); Flucoldex Forte (Флюколдекс Форте); Flucoldex-C
(Флюколдекс-С); Flucoldex-N (Флюколдекс-Н); Flucoldin (Флуколдин); Flucomp
(Флюкомп); Flustop (ФЛЮСТОП); FluZiOZ (ФлюЗиОЗ); Forsodol (Форсодол); Gewadal
(Гевадал)¤; Gripend (Грипэнд); Gripend HotActive (Грипэнд ХотАктив); Grippex
(Гриппекс); Grippoflu Extra Cold and Flu (Гриппофлю От Простуды И Гриппа);
Grippostad (Гриппостад); Grippostad C (Гриппостад С); Ibuclin (Ибуклин); Influblock
(Инфлюблок); Influnorm (Инфлюнорм); Iralgesic (Иралгезик); Kofan (Кофан); Lemsip
(Лемсип); Maxicold (Максиколд); Mexavit (Мексавит)¤; Migrenol (Мигренол); Neoflu
(Неофлю); No-Spalgin (Но-Шпалгин); Panadol Extra (Панадол Экстра); Panoxen
(Паноксен); Paracetamol-C (Парацетамол-С); Paracodamol (Паракодамол)¤; Paralen
Extra (Парален Экстра); Pentaflucin (Пентафлуцин); Pentalgin (Пенталгин); Pentalgin
Plus (Пенталгин Плюс); Prostudox (Простудокс); Quintalgine (Квинталгин); Rinicold
(Риниколд); Rinicold HotMix (Риниколд ХотМикс); Rinza (Ринза); Rinzasip (Ринзасип);
Rinzasip with Vitamin C (Ринзасип с Витамином С); Santoperalgin (Сантопералгин);
Saridon (Саридон); Sedal-M (Седал-М); Sedalgin-Neo (Седальгин-Нео); Solpadeine
(Солпадеин); Stopgripan (Стопгрипан); Theophedrinum-N (Теофедрин-Н); Theraflu
(Терафлю); Theraflu Extratab (Терафлю Экстратаб); TheraFlu Flu and Cold (ТераФлю
от Гриппа и Простуды Экстра); Thomapyrin (Томапирин); Toff Plus (Тофф Плюс);
Trigan-D (Триган-Д); Unispaz (Юниспаз); Unispaz N (Юниспаз Н); Zaldiar (Залдиар);
South Africa: Abflex; Acetapon¤; Actifed Cold & Fever¤; Acuflu P; Acugesil¤; Acurate;
Acustop¤; Adco-Dol; Adco-Flupain; Adco-Kiddipayne; Adco-Payne; Adco-Salterpyn;
Adco-Salterpyn; Adco-Sinal Co; Adco-Sinal NS; Algist¤; Analgen-SA¤; Analgen¤;
Antiflu¤; Antipyn Forte; Antipyn¤; Arcanaflex¤; Arcanaflu¤; Arcanagesic¤; Asalen¤; BDol; Ban Pain¤; Ban Pain; Benylin Day & Night¤; Benylin Four Flu; Besemax; Besenol¤;
Besenol; Betaflex¤; Betapyn¤; Betapyn; Biopyn¤; Briscopyn¤; Bro-N-Pain¤; Bronchiflu¤;
Cetamine¤; Co-Gesic¤; Codipar¤; Codoxol; Cofendyl; Colcaps¤; Colcleer; Colcleer;
Coldvico¤; Colstat; Compral; Coralgesic¤; Corenza C Para-C; Cothera Compound¤;
Decon¤; Degoran C; Degoran Cold & Flu¤; Degoran Plus; Degoran¤; Degoran;
Dentopain Forte; Dentopain; Depain Plus¤; Depain¤; Dequa-Flu; Dimiprol¤; Distalgesic;
Doans Backache Pills¤; Docdol¤; Dolerax¤; Dolorol Forte¤; Dostil¤; Doxsyn¤; Doxyfene;
Dristan Cold ND¤; Dynapayne¤; Efferflu-C; Empacod; Emprazil-A¤; End Pain¤; Endcol
Cold & Flu¤; Endcol¤; Excedrin; Excedrin; Famcod¤; Famucaps¤; Fevapar¤; Flu-Stat;
Flu-Stat; Flucol¤; Fluend; Flusin S; Flusin Sinus; Flusin; Flusin; Flutex Cold and Flu;
Martindale: The Complete Drug Reference
Flutex Cold and Flu; Flutex¤; Forpyn¤; Gen-Payne; Go-Pain; Go-Pain; Goldgesic¤;
Grand-Pa Headache¤; Grippon Cold & Flu; Grippon¤; Grippon; Histacon; Histalix-C¤;
Histamed Compound; Ibumol; Ibupain Forte; Ibupain; Ilvico; Infacet¤; Infapain Forte;
Infapain; Kid-Eeze¤; Kiddyflu; Kodapon¤; KPP¤; Lem-Plus¤; Lemsip¤; Lenadol;
Lenapain; Lentogesic; Lentogesic; Lesspain¤; Lobak¤; Lotem; Lusadol¤; Maxadol
Forte¤; Maxadol¤; Medicod¤; Medipyn; Medipyn; Megapyn; Megapyn; Meprogesic;
Mepromol¤; Mepromol; Merck-Flu¤; Meridol-D¤; Micro-Gesic¤; Mybucod; Mybulen;
Myoflex¤; Mypaid; Myprodol; Napacod; Nitecall¤; Nitrocod¤; Nomopain¤; Nopyn¤;
Noralget¤; Norflex Co; Painagon; Painagon; Painamol Plus; Paincod¤; Painrite SA¤;
Painrite¤; Panado Medsip; Panado-Co¤; Paracetacod¤; Paracodol¤; Parafon¤; Paran¤;
Paxidal¤; Pedigesic¤; Pedpain¤; Propain Forte; Propain¤; Propain; Pynclear¤; Pynmed;
Pynmed; Pynstop; Rexachlor¤; Rocodin¤; Scriptogesic¤; Sedapain¤; Sedinol¤; Setamol
Co¤; Si-Nade¤; Sinaxamol¤; Sinu-Flu¤; Sinuclear; Sinuclear; Sinucon; Sinuend;
Sinugesic; Sinumax Allergy Sinus; Sinumax Cold & Flu Plus Cough¤; Sinumax with
Codeine; Sinumax; Sinustat Flu; Sinustat Flu; Sinustat; Sinustop with Codeine¤;
Sinustop¤; Sinutab ND; Sinutab Sinus Allergy Congestion and Pain; Sinutab with
Codeine; Sinutab¤; Spasmend; Spasmoflex¤; Spectrapain Forte; Spectrapain; Stilpane;
Stilpane; Stilpane; Stopayne; Stopayne; Sudafed Sinus Pain; Sudagesic¤; Suncodin¤;
Suncodin; Supragesic¤; Supragesic; Synaleve¤; Synaleve; Synap; Syndette¤; Syndol¤;
Syndol; Tensolve; Tensopyn; Tenston; Tenston; Tenston; TheraFlu Cold & Flu;
Tramacet; Trinagesic; Tylenol Cold & Flu¤; Tylenol Night Pain¤; Tylenol PM; Vacudol
Forte¤; Vacudol¤; Veganin¤; Vicks Medinite¤; Xeramax¤; Xerogesic¤; Xerotens¤;
Zeropyn¤; Singapore: Anarex; Beacons; Beaflu-Plus; Beagenco¤; Camgesic;
Cetagesic; Childrens Panadol Cold & Flu¤; Chlornamol; Cold; Coldsoft Day; Coldsoft
Night; Conda; Coritab¤; Decolgen Cold & Flu with Vitamin C; Decolgen Cold & Flu;
Decolgen Non Drowse; Decolgen¤; Dhacold¤; Dhaflu¤; Dolpocetmol; Eshlin; Febricol;
Febs; Flucol; Headache; Hi-ringl; Lemsip Cold & Flu; Lemsip Max Cold & Flu; Lemsip
Max Cold & Flu; Lemsip Pharmacy Flu Strength; Migraleve¤; Milidon CF¤; Milidon
Compound¤; Norgesic; Norphen; Orphenadol; Paceco; Pacofen; Panaco; Panadeine;
Panadol Cold & Flu Hot Remedy; Panadol Extra; Panadol Flumax; Panadol for Cold &
Flu¤; Panadol For Cold Relief Extra; Panadol for Cold Relief; Panadol For Cough and
Cold; Panadol Menstrual; Panaflu Plus; Panaflu¤; Paradrine; Paramine¤; Picapan;
Relexic¤; Ricoflu; Robitussin Cold, Cough & Flu¤; Sinuzin-D¤; SP-Febrax; Stona Cold
Caplets; Stona Cold Tablet; Sunflu; Suniton; Triaminic Cold, Cough & Fever; Ultracet;
Uniflu; Unirhinol¤; Yinchi; Spain: Actron Compuesto; Adalgur; Alergical Expectorante;
Martindale: The Complete Drug Reference
Algidol; Algomen¤; Analgilasa¤; Analgilasa; Analgiplus; Anticatarral; Apiretal Codeina;
Baby Rinol¤; Beecham Lemon Miel¤; Beecham Lemon¤; Bisolgrip; Blapidon
Vitaminado¤; Bonciclol¤; Cafersona¤; Calmagrip; Calmanticold Vit C¤; Cerebrino¤;
Cinfatos Complex; Co-Dafalgan¤; Cod Efferalgan; Cofigrip; Colnidin; Coricidin Fuerte¤;
Cortafriol C; Cortafriol Complex; Coxumadol¤; Decima Nil¤; Dimayon¤; Dolgesic
Codeina¤; Dolofarma; Dolomedil; Doscafis¤; Efferalgan Vit C; Enfriestop;
Farmagripine¤; Febrectal¤; Fenalgin¤; Fiorinal Lact or Adul¤; Fiorinal Codeina¤;
Fiorinal¤; Fludeten; Fluimucil Complex; Frenadol Complex; Frenadol PS; Frenadol;
Frenaseltz¤; Frialgina; Frual¤; Gelocatil Codeina; Gelogrip¤; Gripakin; Gripofren¤;
Hemicraneal; Homocodeina Timol¤; Hubergrip¤; Ilvico; Lafor; Liderplus¤; Lumbaxol
Para¤; Medinait; Melabon¤; Meloka¤; Meridol¤; Microsupos Analg Antite¤; Microsupos
Antiespasmo¤; Migraleve; Mintayax; Neocibalena; Novag Grip Fenilefrina; Novag Grip;
Oberdol¤; Okalgrip; Pazital; Pharmagrip Duo; Pharmagrip; Pirifedrina¤; Plivamol;
Pontalsic; Pridio; Propalgina Plus; Propalgina PS Hot Lemon¤; Pulmo Hubber Bals Sol¤;
Ramatocina¤; Ratiogrip; Rectolmin Antiterm¤; Relaxibys¤; Rinomicine Activada;
Rinomicine; Rinomicine; Robaxisal Compuesto; Saldeva; Saridon; Sedatermin¤;
Serragrip; Sinefricol¤; Sinutab¤; Spaltina¤; Spirsa¤; Talgo Codeina¤; Termalgin
Codeina; Trophires Rectal Lact¤; Veganin¤; Vicks Medinait¤; Vincigrip Balsamico¤;
Vincigrip; Viralkey; Yendol; Zaldiar; Sweden: Citodon; Dexodon¤; Distalgesic¤; Lobac¤;
Norgesic; Panocod; Somadril Comp¤; Switzerland: Acide acetylsalicylique comp.
"Radix"¤; Angifebrine¤; Antigrippine C¤; Antigrippine Comp.¤; Antigrippine¤; Becetamol
C; Caposan¤; Cerebrol sans codeine¤; Cerebrol¤; Co-Becetamol; Co-Dafalgan; CoTylenol¤; Codol¤; Comprimes analgesiques "S"¤; Contre-Douleurs C; Contre-Douleurs¤;
Dafalgan plus C; Demogripal C; Demogripp¤; Dialgine forte¤; Dialgine; Distalgesic¤;
DoloCitran C; Dolostop¤; Dorsilon¤; Efferalgan C¤; Epizon¤; Febracyl¤; Febradolor sans
codeine¤; Febrinal¤; Finimal¤; Fluimucil Grippe Day & Night; Fribagyl sans codeine¤;
Fribagyl¤; Gelonida¤; Gewodine¤; Grippalgine N¤; Grippostad C¤; Gubamine¤;
Influbene C; Irocopar¤; Kafa plus cafeine; Lagaflex¤; Linervidol¤; Lysedil compositum¤;
Malex¤; Melabon N¤; Migraeflux¤; Migraine-Kranit; Migraleve¤; Neo Citran
Grippe/refroidissement; Neo-Cibalgin¤; Nina cum Diphenhydramino¤; No Grip C¤; NoFlu¤; Norgesic¤; Pamed-C¤; Panadol Antigrippine; Panadol C; Panadol Extra; Parafon¤;
Pretuval C; Pretuval; Quadronal¤; Rhinofebral¤; Sanalgin N; Saridon¤; Sinedal¤;
Sonotryl¤; Spedralgin sans codeine¤; Stellacyl N¤; Supadol¤; Talvosilen¤;
Thomapyrine¤; Trancopal compositum¤; Treupel Grippe; Treupel sans codeine¤; Treupel
simplex¤; Treupel¤; Treuphadol Plus¤; Trimedil¤; Triplex sans codeine¤; Triplex¤; Vicks
Martindale: The Complete Drug Reference
Medinait; Zafor¤; Zaldiar; Zolben C; Thailand: A-Mol Plus; Acetacol-P; Acetacol;
Acetapyrin-C; Alaxan PI; Amcopan Plus; Anahis; Anhista; Apracur PC; Apracur; Bruno;
Brustan; Buscopan Plus¤; C-Colotab; Cariso-Co¤; Carisoma Compound¤; Caritasone¤;
Cecold¤; Cemol Cold¤; Cenasic; Cencold¤; Cenpadol¤; Cetan¤; Cetaphen; Cezox;
Chintacold; Chlorhistan¤; Codarin-A; Codicet; Codigesic; Colatus; Colcap; Cold-tab;
Coldate; Coldetab; Coldocap; Coldosian; Coldy; Cologen; Coltab; Conaid; Coolby Cough;
Cori-C; Corilax; Coritab¤; Cotenol¤; Decolgen DE¤; Decolgen Plus; Decolgen Prin;
Decolgen; Decono; Depygon¤; Deramol; Dobil¤; Dologen; Dorpane; Dysmenic;
Fagesic¤; Falfon¤; Fecol; Fecol; Fiddy; Fut-Fit; Gendecon¤; GPO Gesic; Hiscolgen;
Hisprin¤; Huddy-Pe; Hyosman Plus; KB Fedamol; KB Gin; KBDC; Kintal¤; Koolnox;
Locko; Lofen; M-Gesic; Masapara w/ Codeine; MCXY; Med-Myolax¤; Medamol Co¤;
Meddy; Medgesic; Milagin; MP Fon; Muscelax¤; Muscol; Muscolic; Muslexac; Mycol;
Myodrine; Myoflex; Myopa; Myopar¤; Myopas; Myora; Myoserv¤; Myosic; Myospa;
Mypara Plus; Nabesac; Nasa W/ Codeine; Neofon; Neosec; Neozep; Nokole; Noraphen;
Norgesic; Norgetex; Norgic; Norphen; Norsica; Novapam¤; Nuosic; Nurasic; Nuta;
Nutacold; Orano; Orapa; Orflex; Orgesic; Ornadine; Orpar; Orphengesic; Orphensic;
Pabron XT; Pacogen; Pacopan; Painol; Painol; Panofen; Pantagen; Paracin; Paracol-Dex;
Paracol; Paradeine; Paradine; Parafon¤; Paramed Co¤; Parco-D; Parcono; Parina;
Pasodol¤; Patargesic; Pedia-Col; Pedia-Col; Pharcold; Poli-Relaxane; Polixan¤; Polydol;
Pormus; Pronadrine; Prospa; Pyrecol; Raxsoma¤; Relar; Relaxic; Rena; Rexodrin;
Rumatifen-Plus¤; Sinpyrin; Sinuzin-D¤; Skelan; Spasgone; Sycold¤; Tiffy Dey; Tiffy Fu;
Tiffy Kiddi; Tiffy; Tiffy; Togesic; Tylenol with Codeine; Ultracet; Unigan; Veracold;
Vorafon; Turkey: A-ferin Plus; A-ferin; A-ferin; A-ferin; A-ferin; Adafen; Afebryl;
Alfarol; Aljil; Apex; Asko; Avmigran; Babyrhinol; Benical Cold; Buscopan Plus; Cetafluforte; Codasel; Coldeks; Coldsal; Comax; Contex; Corsal; Darvolin; Deflu; Deksan;
Doladamon; Dorfan; Dorsilon; Dristan; Ekorinol¤; Epidosin Compozitum; Ergafein;
Forza; Gerakon; Geralgine Plus; Geralgine-Hot; Geralgine-K; Geralgine-P; Gribex Hot;
Gripaljin; Gripamol; Gripin Kase; Kataljin-P; Katarin Forte; Katarin; Kongest; Kuiflex;
Kuilil; Lokman Kase; Maxihot; Medafein; Medicold; Mepadol; Minoset Plus; Miyorel; Molit
Plus; Muskazon; Nopain Plus; Novaldon; Oledro; Oledro; Pacofen-S; Pacofen; Panadol
Extra; Panalgine; Para-Nox; Parafon; Parakodin; Paramidon; Parasinus; Parol Cold;
Parol Hot; Pedimat; Peditus; Peraljin; Pir Hot D; Pirosal; Remidon; Setakaf; Spalt;
Spasmo-Panalgine; Spazmol Plus; Spazmotek Plus; Tamol Cold; Termalgine Plus;
TheraFlu Forte; TheraFlu; TheraFlu; TheraFlu; Thomapyrin; Tylol Cold; Tylol Hot; Tylol
Plus; Vermidon Cold; Vermidon Hot; Vermidon-K; Vermol; Vicks MediNait; Wintus;
Martindale: The Complete Drug Reference
Zaldiar; United Arab Emirates: Adol Allergy Sinus; Adol Cold; Adol Compound; Adol
Extra; Adol PM; Adol Sinus; Flukit; Flukit; Muscadol; United Kingdom: Actron¤; Alka
XS Go¤; Alka-Seltzer XS; Anadin Cold Control Flu Strength¤; Anadin Cold Control¤;
Anadin Extra; Andrews Answer¤; Banimax¤; Beechams Active Cold Relief; Beechams
All-In-One; Beechams Cold & Flu; Beechams Decongestant Plus with Paracetamol;
Beechams Flu-Plus; Beechams Flu-Plus; Beechams Powders Capsules; Benylin 4 Flu¤;
Benylin 4 Flu; Benylin Cold & Flu; Benylin Cold & Flu; Benylin Day & Night; Benylin
Mucus Cough & Cold All in One Relief; Boots Cold & Flu Relief Hot Lemon; Boots Cold &
Flu Relief; Boots Decongestant Tablets; Boots Dental Pain Relief¤; Boots Maximum
Strength Cold & Flu Relief; Boots Tension Headache Relief¤; Cafadol¤; CalCold; Calpol
Extra¤; Calpol Night; Catarrh-Ex; Coda-Med¤; Codanin¤; Codipar; Cold Relief Daytime¤;
Cold Relief Night-Time¤; Cold Relief¤; Cold Relief; Cold Relief; Coldrex¤; Cosalgesic¤;
Covonia Cold & Flu; Day & Night Nurse; Day Cold Comfort¤; Day Nurse; De Witt's
Analgesic; Disprin Extra; Distalgesic¤; Doans Backache Pills; Dolvan; Domperamol¤;
Dozol; E.P.¤; Extra Power Pain Reliever; Femerital¤; Feminax; Flurex Bedtime¤;
Flurex¤; Formulix¤; Fortagesic¤; Galake¤; Galpharm Flu Relief; Hedamol¤; Hedex Extra;
Hedex Headcold¤; Hot Lemon Powders¤; Kapake; Lem-Plus¤; Lemsip Childrens Six+
Cold & Flu Relief; Lemsip Cold & Flu Breathe Easy; Lemsip Cold & Flu Combined Relief¤;
Lemsip Cold & Flu Max Strength Capsules; Lemsip Cold & Flu Max Strength; Lemsip Cold
& Flu Original; Lemsip Flu Strength¤; Lemsip Junior Blackcurrant¤; Lemsip Max Strength
Sinus Relief; Lemsip Night Time¤; Lemsip Non-Decongestant¤; Lemsip Pharmacy Flu
Strength; Lemsip Pharmacy Power+¤; Lobak¤; Medised for Children; Medised¤;
Medocodene; Midrid; Migraleve; Migralift¤; Mu-Cron¤; Night Cold Comfort¤; Night
Nurse; Nirolex Day Cold & Flu; Nirolex Night Cold & Flu; Non-Drowsy Sinutab; NonDrowsy Sudafed Congestion Cold & Flu; Non-Drowsy Sudafed Dual Relief; Numark Flu
Relief; Numark Max Strength Cold & Flu; Nuromol; Nurse Sykes Powders; Olbas
Powerflu plus Vitamin C; Otrivine Mu-Cron; Painex; Pameton¤; Panadeine¤; Panadol
Extra; Panadol Night; Panadol Ultra; Panerel¤; Paracets Cold Relief; Paracets Plus;
Paracodol; Paradote¤; Parahypon¤; Parake¤; Paramax; Paramol; Pardale¤; Paxalgesic¤;
Paxidal; Phensic Dual Action¤; Powerin¤; Propain Plus; Propain; Real Lemon Cold
Powders¤; Remedeine; Resolve Extra; Resolve; Rinurel¤; Ronpirin APCQ¤; Ronpirin Cold
Remedy¤; Sinitol¤; Sinutab Nightime¤; Solpadeine Headache; Solpadeine Max;
Solpadeine Plus; Solpadol; SP¤; Sudafed Mucus Relief Triple Action Cold & Flu; Syndol;
Tixyplus; Tramacet; Triogesic¤; Tylex; Ultramol; Uniflu with Gregovite C; Unigesic¤;
Veganin; Vicks Cold Care¤; Vicks Daymed; Vicks Daymed; Vicks Medinite; Vicks Sinex;
Martindale: The Complete Drug Reference
Zapain; Ukraine: Anticataral (Антикатарал); Bol-Ran (Бол-Ран)¤; Citramon Extra
(Цитрамон-Экстра)¤; Citramon Forte (Цитрамон-Форте); Coldact Flu Plus (Колдакт
Флю Плюс); Coldrex (Колдрекс); Coldrex HotRem (Колдрекс Хотрем); Coldrex Maxgrip
Lemon (Колдрекс Максгрип Лимон); Coldrin (Колдрин); Copacyl (Копацил); Daleron C
(Далерон C); Dipren (Дипрен)¤; Dolaren (Доларен)¤; Farmadol (Фармадол)¤; Flucold
(Флюколд); Flucold-N (Флюколд-N)¤; Flucoldex (Флюколдекс)¤; Gripex (Грипекс);
Gripex Hot Effect (Грипекс Хот Эффект)¤; Gripex Hotactive (Грипекс Хотактив);
Gripex Max (Грипекс Макс); Gripex Night (Грипекс Ночной); Gripex Start (Грипекс
Старт); Grippocitron (Гриппоцитрон); Grippostad C (Гриппостад С); Helpex Anticold
(Хелпекс Антиколд); Helpex Anticold DX (Хелпекс Антиколд DX); Helpex Hot Cap
(Хелпекс Хот Кап); Kofan (Кофан); Maxicold (Максиколд); Milistam Multisymptomic
(Мілістан Мультисимптомный)¤; Milistan Hot Tea for Children Orange (Мілістан
Гарячий Чай Для Дітей Зі Смаком Апельсина)¤; Milistan Hot Tea lemon (Мілістан
Гарячий Чай Зі Смаком Лимона)¤; No-Spalgin (Но-Шпалгин); No-Spasma (НоСпазма)¤; Novalgin (Новалгин)¤; Pentased (Пентасед); Rhinostop (Риностоп); Rinza
(Ринза); Rinza Hotsip (Ринза Хотсип); Rinza Hotsip with Vitamin C (Ринза Хотсип с
Витамином C); Sedal-M (Седал-М); Solpadeine (Солпадеин); Spasmo-Proxyvon
(Спазмо-Проксивон)¤; Stopgripan (Стопгрипан); Tamipul (Тамипул); Theraflu
(Терафлю); Theraflu Extra (Терафлю Экстра); Theraflu Extratab (Терафлю
Экстратаб); TheraFlu Flu and Cold (Терафлю Від Грипу Та Застуди); Theraflu SNS
(Терафлю СНС)¤; Trinell (Тринелл); Tylol Hot (Тайлол Ксот); Unispas (Юниспаз);
Zaldiar (Залдіар)¤; United States: 4-Way Cold Tablets¤; Aceta with Codeine; AcetaGesic; Acetaco¤; Acid-X; Aclophen; Actifed Cold & Sinus; Actifed Plus; Actifed Sinus
Daytime; Actifed Sinus Nighttime; Alagesic LQ; Algisin¤; Alka-Seltzer Plus Cold &
Cough¤; Alka-Seltzer Plus Cold & Cough; Alka-Seltzer Plus Cold; Alka-Seltzer Plus Day &
Night Cold; Alka-Seltzer Plus Day & Night Cold; Alka-Seltzer Plus Day Cold; Alka-Seltzer
Plus Day Non-Drowsy Cold; Alka-Seltzer Plus Fast Crystal Packs; Alka-Seltzer Plus Night
Cold; Alka-Seltzer Plus Night-Time Cold; Alka-Seltzer Plus Nose & Throat; Alka-Seltzer
Plus Original Cold Formula; Alka-Seltzer Plus Regular Seltzer Multi-Symptom Cold Relief;
Alka-Seltzer Plus Sinus; All-Nite Cold Formula; Allerest Allergy & Sinus Relief; Allerest
Headache Strength; Allerest Sinus Pain Formula; Alumadrine¤; Amacodone¤; Amaphen
with Codeine; Amaphen¤; Americet; Anabar; Anacin Advanced Headache; Anatuss¤;
Anexsia; Anolor; Anoquan¤; Arcet¤; Arthritis Foundation Nighttime¤; Aspirin Free Anacin
PM; Aspirin Free Excedrin Dual¤; Aspirin Free Excedrin; Aspirin Plus¤; Aspirin-Free Bayer
Select Allergy Sinus; Aspirin-Free Bayer Select Head & Chest Cold; Aspirin-Free Bayer
Martindale: The Complete Drug Reference
Select Headache¤; Axocet¤; Back Pain-Off; Balacet¤; Bancap HC¤; Bayer Select Chest
Cold; Bayer Select Flu Relief; Bayer Select Head Cold; Bayer Select Maximum Strength
Headache¤; Bayer Select Maximum Strength Menstrual¤; Bayer Select Maximum
Strength Night Time Pain Relief; Bayer Select Maximum Strength Sinus Pain Relief;
Bayer Select Night Time Cold; BC Allergy Sinus Headache; Be-Flex Plus¤; Benadryl
Allergy Plus Sinus Headache; Benadryl Allergy/Cold; Benadryl Cold Nighttime Formula;
Benadryl Cold/Flu¤; Benadryl Plus¤; Biotab¤; Biphenox; BP Poly-650; Bromaline Plus¤;
Bromo Seltzer Effervescent Granules; Bucet¤; Bufferin AF Nite Time¤; Buffets II¤;
Bupap; Butex; By-Ache; Cafgesic Forte¤; Capacet; Capital with Codeine; Cephadyn;
Ceta Plus¤; Children's CoTylenol¤; Childrens Cepacol¤; Chlor-Trimeton Allergy Sinus¤;
Co-Apap; Co-Gesic; Co-Hist; Cocet; Codalan¤; Codaphen¤; Codimal¤; Cold Control;
Cold Relief¤; Cold Tablets-D¤; Cold Tablets¤; Coldrine; Combiflex ES¤; Combiflex;
Comtrex Acute Head Cold; Comtrex Allergy-Sinus; Comtrex Day & Night Maximum
Strength; Comtrex Day & Night Multi-Symptom; Comtrex Day/Night Flu Therapy;
Comtrex Hot Flu Relief; Comtrex Liqui-Gels¤; Comtrex Maximum Strength Night-time
Cold & Cough; Comtrex Multi-Symptom Deep Chest Cold; Comtrex Sinus & Nasal
Decongestant; Comtrex; Congespirin¤; Congestant D¤; Congestant; Contac Cold + Flu
Day & Night; Contac Cold + Flu; Contac Cough & Sore Throat¤; Contac Day & Night
Allergy Sinus; Contac Day and Night Cold & Flu Caplets; Contac Night Cold & Flu
Caplets¤; Contac Severe Cold & Flu Hot Medicine¤; Contac Severe Cold & Flu
Nighttime¤; Contac Severe Cold & Flu Non-Drowsy¤; Contac Severe Cold and Flu
Formula¤; Contac Sinus Formula¤; Coricidin D¤; Coricidin Maximum Strength Sinus
Headache¤; Coricidin; Cotabflu; Cough Formula Comtrex; Covangesic¤; Dapacin Cold¤;
Darvocet-N¤; Darvocet¤; Decongestant; Demerol APAP¤; DHC Plus; Diabetic Tussin Cold
& Flu; Diabetic Tussin Night Time Cold/Flu Formula; Dilotab; Dimetapp Cold & Fever;
Dimetapp Cold & Flu¤; Dimetapp Nighttime Flu; Dimetapp Non-Drowsy Flu; Dolacet;
Dolgic LQ; Dolgic Plus; Dolgic; Dolprn #3¤; Double-Action Toothache Kit; Dristan Cold &
Flu; Dristan Cold Caplets; Dristan Cold Maximum Strength Multi-symptom Formula;
Dristan Cold Maximum Strength No Drowsiness Formula; Dristan Cold Multi-Symptom
Formula; Dristan Cold; Dristan Juice Mix-in; Drixoral Cold & Flu; Drixoral Cough & Sore
Throat; Drixoral Plus; Duadacin Extra Strength Cold & Flu¤; Duadacin¤; Duocet;
Durabac Forte; Durabac; Duradrin¤; Duraflu; Duratuss A; Duraxin; Dynafed Plus¤; ELor¤; Endocet; Endolor; Epidrin; Esgic with Codeine¤; Esgic-Plus; Esgic; Excedrin Back &
Body Extra Strength; Excedrin Migraine; Excedrin PM; Excedrin QuickTabs¤; Excedrin
Sinus Headache Aspirin Free; Excedrin Tension Headache; Excedrin; Extra Strength Pain
Martindale: The Complete Drug Reference
Reliever PM; Extra Strength Pyrroxate¤; Extra Strength Tylenol Headache Plus¤; Fem1¤; Fem-Etts¤; Fioricet with Codeine; Fioricet; Fiorpap¤; Flexaphen¤; Flextra; Flu, Cold
& Cough Medicine; Gelpirin-CCF¤; Gelpirin¤; Genacol; Genagesic¤; Gendecon; Genite;
Goody's Headache Powders; Goodys Extra Strength; Goodys PM; Headrin Extra
Strength; Histagesic Modified; Histenol-Forte; Histex SR; Histosal¤; Hy-Phen¤; Hycet;
Hyco-Pap¤; Hycomine Compound; Hydrocet¤; Hydrogesic; Hyflex¤; Isocet¤; Isocom¤;
Isopap¤; Kolephrin/DM; Kolephrin; Lagesic; Legatrin PM; Levacet; Liquicet; Lobac¤;
Lorcet 10/650; Lorcet Plus; Lorcet-HD¤; Lortab; Lurline PMS; Magnacet; Major-gesic;
Mapap Cold Formula; Mapap Sinus Congestion & Pain; Margesic H; Margesic No. 3¤;
Margesic; Marten-Tab; Maxidone; Maxiflu DM; Maximum Strength Arthriten¤; Maximum
Strength Dristan Cold; Maximum Strength Midol Multi-Symptom Formula¤; Maximum
Strength Midol PMS¤; Maximum Strength Ornex; Maximum Strength Sine-Aid; Maximum
Strength Sudogest Sinus; Medi-First Extra Strength Pain Relief; Medi-Flu¤; Medigesic¤;
Medipain¤; MegaMor¤; Melagesic PM; Menoplex¤; Midchlor¤; Midol Maximum Strength
Multi-Symptom Menstrual; Midol PM; Midol Pre-Menstrual Syndrome; Midol Teen
Formula; Midrin; Migragesic IDA; Migralam¤; MigraTen; Migratine¤; Migrazone; MultiSymptom Tylenol Cough with Decongestant; Multi-Symptom Tylenol Cough; Mus-Lax¤;
Narvox; ND-Gesic; New Acute Cold Formula¤; Night Time Cold/Flu Relief; Nighttime
Pamprin; Nite Time Cold Formula; No Drowsiness Sinarest; No-Drowsiness Allerest;
Nodolor; Norcet¤; Norco; Norel Plus¤; Norel SR; NyQuil Hot Therapy; NyQuil Nighttime
Cold/Flu; Nytcold Medicine; Oncet; Orbivan; Original Midol Multi-Symptom Formula¤;
Ornex Severe Cold No Drowsiness¤; Ornex; Pacaps; Pain Reliever¤; Pain-gesic; Painaid
Back Relief; Painaid BRF Back Relief Formula; Painaid ESF Extra-Strength Formula;
Painaid PMF Premenstrual Formula; Painaid; Pamprin; Panacet¤; Panlor¤; Percocet;
Percogesic Extra Strength; Percogesic; Perloxx; Pertussin All-Night PM¤; Phanacol¤;
Phenapap Sinus Headache & Congestion; Phenapap; Phenaphen with Codeine¤;
Phenate¤; Phenylgesic; Phrenilin w Caffeine and Codeine; Phrenilin with Codeine No.3¤;
Phrenilin; Pimalev; Poly-Vent Plus; Premsyn PMS; Presalin¤; Primlev; Prodrin;
Promacet; Prominol; Propacet¤; Protid; Proxy¤; Relagesic; Remcol Cold¤; Remcol-C¤;
Repan CF¤; Repan; Respa C&C; Rhinocaps¤; Rhinogesic¤; Rid-a-Pain with Codeine¤;
Robitussin Night Relief; Roxicet; Roxilox; S-A-C¤; Saleto-D¤; Saleto; Salocol¤;
Salphenyl¤; Sedapap; Simplet; Sinadrin PE; Sinadrin Plus; Sinapils¤; Sinarest; Sine-Aid
Maximum Strength; Sine-Off Maximum Strength Allergy/Sinus; Sine-Off Maximum
Strength No Drowsiness Formula; Sine-Off Sinus/Cold; Singlet; Sinubid¤; Sinulin¤;
Sinus Excedrin; Sinus-Relief; Sinutab Maximum Strength Sinus Allergy¤; Sinutab Sinus
Martindale: The Complete Drug Reference
Maximum Strength; Sinutab Without Drowsiness; Sinutrex Extra Strength¤; Sominex
Pain Relief; Spasgesic¤; St. Joseph Cold Tablets For Children¤; Staflex; Stagesic;
Sudafed Cold & Cough; Sudafed PE Multi-Symptom Cold & Cough; Sudafed PE MultiSymptom Severe Cold; Sudafed PE Nighttime Cold; Sudafed PE Sinus Headache;
Sudafed Severe Cold; Sudafed Sinus & Cold Non-Drowsy¤; Sudafed Sinus; Supac¤;
Super Cold Tabs¤; Super Strength Sinadrin¤; T-Gesic; Talacen¤; Tencet; Tencon; TenolPlus¤; Tetra Caplets¤; Theracaps¤; Theracof Plus; Theraflu Caplets Nighttime Severe
Cold; Theraflu Daytime Severe Cold & Cough; TheraFlu Daytime Severe Cold¤; TheraFlu
Flu & Chest Congestion Non-Drowsy; TheraFlu Flu and Cold; TheraFlu Flu, Cold & Cough;
Theraflu Nighttime Severe Cough & Cold; TheraFlu Non-Drowsy Severe Cold; Theraflu
Severe Cold & Cough Daytime/Nighttime; TheraFlu Severe Cold; Theraflu Warming
Relief Daytime Multi-Symptom Cold; Theraflu Warming Relief Flu & Sore Throat; Trezix;
Tri-Pain¤; Triad; Triaminic Allergy Sinus & Headache; Triaminic Cold & Sore Throat;
Triaminic Cough & Sore Throat; Triaminic Flu, Cough & Fever; Triaminic Throat Pain &
Cough; Triaminicin Cold, Allergy, Sinus¤; Triaprin-DC¤; Triaprin¤; Tricom¤; Trigesic¤;
Trycet¤; Two-Dyne¤; Ty-Cold¤; Tylenol Allergy Complete Multi-Symptom; Tylenol
Allergy Complete NightTime; Tylenol Allergy Multi-Symptom; Tylenol Allergy Sinus Day
& Night; Tylenol Chest Congestion Daytime; Tylenol Children's Cold Plus Cough; Tylenol
Children's Cold; Tylenol Childrens Plus Cold Nighttime; Tylenol Childrens Plus Flu;
Tylenol Childrens Plus Multi-Symptom Cold; Tylenol Cold Complete Formula; Tylenol
Cold Effervescent¤; Tylenol Cold Non-Drowsy; Tylenol Cold Severe Congestion; Tylenol
Flu Maximum Strength Non-Drowsy; Tylenol Flu Maximum Strength; Tylenol Flu
NightTime; Tylenol Infants Drops Plus Cold; Tylenol Plus Cold & Cough Infants; Tylenol
PM Extra Strength; Tylenol Severe Allergy; Tylenol Sinus Congestion & Pain Nighttime
Caplets; Tylenol Sinus Congestion & Pain Severe Daytime Caplets; Tylenol Sinus NonDrowsy; Tylenol Sore Throat Nighttime; Tylenol with Codeine; Tylox; Ultracet; Unisom
PM Pain SleepCaps; Unisom with Pain Relief; Vanquish; Vicks DayQuil Multi-Symptom
Cold/Flu Relief; Vicks DayQuil Sinex; Vicks DayQuil Sinus Pressure & Pain Relief; Vicks
Formula 44M Cough, Cold, & Flu Relief; Vicks NyQuil LiquiCaps; Vicks NyQuil MultiSymptom Cold Flu Relief; Vicks NyQuil Sinex; Vicodin; Viro-Med¤; Vopac; Womens
Tylenol Multi-Symptom Menstrual Relief; Wygesic¤; Xodol; Xolox; Zamicet; Zebutal;
ZFlex; Zgesic; Zydone; Venezuela: Acuten; Adolen; Alipal Forte¤; Alivet Dia; Alivet;
Alivetforte; Alivetnoc; Alres; Angrip Noche; Angrip; Ascafyl; Atamel Plus; Atamelco;
Beseroldos; Broxolgrip Dia; Broxolgrip Noche; Buscapina Plus; Cadafen Grip¤; Cafenol;
Clariflu; Clarigrip; Clorace; Coricidin; Corilin; Difen; Dol; Histagrip para adultos;
Martindale: The Complete Drug Reference
Histagrip pediatrico; Ilvico; Ivagan; Letydol; Mercindol; Nipe; Nipe; Norgesic; Parsel;
Resprin; Rilan; Rinot; Robaxifen; Saridon¤; Sinutab¤; Sinutil; Sinutil; Tainol¤;
Tempragrip Dia y Noche; Tempragrip; Tempragrip; Tempraplus; Teragrip D; Teragrip
Forte Dia/Forte Noche; Teragrip Forte Dia; Teragrip Forte Noche; Teragrip Plus¤;
Teragrip; Teragrip; Teragripem; Tylex CD; Ultracet; Uniakum; Uniakum; Zaldiar;
Pharmacopoeial Preparations (Latest modification: 06-Dec-2011)
BP 2012: Co-codamol Capsules; Co-codamol Tablets; Co-dydramol Tablets; Coproxamol Tablets; Dispersible Paracetamol Tablets; Effervescent Co-codamol Tablets;
Paediatric Paracetamol Oral Solution; Paediatric Paracetamol Oral Suspension;
Paracetamol and Caffeine Tablets; Paracetamol Capsules; Paracetamol Oral Suspension;
Paracetamol Suppositories; Paracetamol Tablets; Paracetamol, Codeine Phosphate and
Caffeine Capsules; Paracetamol, Codeine Phosphate and Caffeine Tablets; Soluble
Paracetamol and Caffeine Tablets; Soluble Paracetamol Tablets; USP 35:
Acetaminophen and Aspirin Tablets; Acetaminophen and Caffeine Tablets;
Acetaminophen and Codeine Phosphate Capsules; Acetaminophen and Codeine
Phosphate Oral Solution; Acetaminophen and Codeine Phosphate Oral Suspension;
Acetaminophen and Codeine Phosphate Tablets; Acetaminophen and Diphenhydramine
Citrate Tablets; Acetaminophen and Pseudoephedrine Hydrochloride Tablets;
Acetaminophen and Tramadol Hydrochloride Tablets; Acetaminophen Capsules;
Acetaminophen Extended-Release Tablets; Acetaminophen for Effervescent Oral
Solution; Acetaminophen Oral Solution; Acetaminophen Oral Suspension;
Acetaminophen Suppositories; Acetaminophen Tablets; Acetaminophen, Aspirin, and
Caffeine Tablets; Acetaminophen, Chlorpheniramine Maleate, and Dextromethorphan
Hydrobromide Tablets; Acetaminophen, Dextromethorphan Hydrobromide, Doxylamine
Succinate, and Pseudoephedrine Hydrochloride Oral Solution; Acetaminophen,
Diphenhydramine Hydrochloride, and Pseudoephedrine Hydrochloride Tablets; Butalbital,
Acetaminophen, and Caffeine Capsules; Butalbital, Acetaminophen, and Caffeine
Tablets; Hydrocodone Bitartrate and Acetaminophen Tablets; Isometheptene Mucate,
Dichloralphenazone, and Acetaminophen Capsules; Oxycodone and Acetaminophen
Capsules; Oxycodone and Acetaminophen Tablets; Propoxyphene Hydrochloride and
Acetaminophen Tablets; Propoxyphene Napsylate and Acetaminophen Tablets
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