Date of submission of tenders has been extended up to 30.01.2016 at 14.00 hrs.
General requirements for all equipment:
All vendors should quote only their high end equipment. Providing misinformation lead
to disqualification without stating any reasons.
All claims should be supported with authentic published documents. Laboratory manuals are not
acceptable. Published papers for claims should be submitted.
Documents pertaining to installation qualification (IQ), operational qualification (OQ) and
performance qualification (PQ) for analytical equipment qualification should be submitted.
All equipment should be quoted along with suitable branded equipment table/stand, dedicated for
the equipment concerned.
Amendments to the Tender No.
* GC-MS/MS
SL.NO. 1 Gas Chromatograph: Head space analyser of 100 vial capacity should be quoted as
optional.
MS/MS triple quadrupole system: Mass range: 10-1050 amu or better
Vacuum system: A robust high efficiency vacuum system with minimum maintenance and
utility with low noise level and system with high capacity oil free turbomolecular pump.
EI-MRM mode IDL: WITH 1 µL in column injection and 100 msec or less dwell
time, 30 m column; IDL of the machine for OFN at the same conditions should be ≤0.5
fg. XIC of IDL concentration should be provided.
Performance requirements:
1. Sensitivity of the equipment – EI-MRM transition 272-222 at unit resolution, 1 µL on
column injection and 100 msec or less dwell time, in 30 m column, the IDL at this condition
should be ≤ 0.5 fg. XIC at IDL concentration should be provided. The % RSD for five
sequential injections should not exceed <5%. Related details such as chromatogram, details
of GC and MS parameters, injection volume, date and time of analysis using GFR Part II
compliant software.
Documentary proofs on IDL pertaining to the quoted machine should be submitted with the
quote. The IDL claim should be demonstrable in the new machine. This is included in the
IQ OQ requirement of the machine.
2. Documentary evidence to be provided. Limit of quantification for δ-methrin,
quinalphosmalathion and chlorpyriphosin fish matrix with full details as above. Quantified
concentration in the provided spiked matrix should be reported. Analysis report should be
from the same machine quoted.
3. Analysis of pesticide residues using QuEChERs method. LOD for major pesticides in fish
matrix with full details as above. 50 numbers QuEChERS tube and cleanup kit should be
quoted for demonstration purpose.
Accessories
1. Gas cylinders, minimum two nos. with necessary license and pressure gauge Calibrated
digital flow meter with certification from an accredited lab
Point No. 3.GC-MS/MS vials for autosampler: 5000 nos. Headspace vials 100 nos. and two
crimpers should be quoted as optional.
Point No. 7. Analytical standard for dioxins (7 congeners), furans (10 congeners), dioxin like
PCBs (12 congeners) should be quoted and purchase of the same for CIFT should be facilitated.
Pesticide multiresidue mix (at least 200 compounds) from Restek or equivalent should be
provided. The standards should be QC compliant and necessary certificates should be provided.
* SPECIFICATION FOR BENCH TOP QUADRUPOLE ICPMS COUPLED WITH
HPLC/ION CHROMATOGRAPH
Simple and easy to use ICP MS for multi-elemental analysis with high-throughput capability;
capable of coupling with HPLC/IC for speciation of elements such as Cadmium, Chromium,
Arsenic, Mercury andLead.
The instrument should have 21 CFR II compliant standard software. Adequate literature and
published articles in peer reviewed journals should be attached to support the claims. All vendors
should quote under FOB basis in Foreign Currency. CIFT has his own freight forwarder for
transporting and clearing the consignment.
* Sl. No. 1: Sample Introduction, point 5:
All the gases for Nebulizer, auxiliary, plasma, CCT gases, Reaction should be controlled by
Mass Flow Controller or better system.
* Sl. No. 1: Ion Optics system, point 1:
The ICPMS must have transfer lens system with 90 degree ion optics system or better to
provide high ion transmission across the entire mass range.
* Sl.No.1: Quadrupole assembly, point 6:
Scanning speed >3,000 amu / sec or higher for entire mass range
* Sl.No.1: Performance specification, point 5:
Sensitivity:
Be/Li > 30 x106 cps/ppm
Mg/Co >15.0 x106 cps/ppm
In or Y > 40.0 x106 cps/ppm
U or TI >40.0 x106 cps/ppm
* Sl.No.1: Accessories and standards (ICP), point 3 and 4:
Gas cylinders for required operation to be supplied (4 for carrier gas, others 2 each)
Suitable gas for removing polyatomic interference in reactive mode
* Point 6: Sensitive weighing balance (200g / 0.01 mg)
* Point 7: On-Line 20 KVA UPS along with branded Amaron/Exide 150 AH batteries for a
minimum
backup time of 2 hr.
* Point 9: Also quote for spares and consumables including standards required for all the
operations
for three years
* Sl. No.2 : Specifications for Ion Chromatography-High Performance Liquid
Chromatography
Ion
Chromatography
System should have the capability to connect with ICP-MS for
metal speciation studies
Quaternary Gradient Pump with built in degassing system
Flow rate: 0.001 - 10 ml/min
Flow rate accuracy: <0.1%
Pressure Range: 6000 psi
Autosampler and optional eluent generator
* 3 sections for Separation, Detection and Automation
* Houses Electrochemical detectors, columns
* Lower Section Temperature Range: 10 - 70⁰C in 0.1⁰C
increments.
* Capable of housing 2 columns of 1-9 mm: 250 cms Length
ED Electrochemical Detector
* Provides efficient detection for multiple analysis.
* Detection Types: Single and dual electrochemical detection.
Compatible with 0.4 mm, 2mm to 4 mm id columns
* Interchangeable Working Electrode: Gold glassy carbon, platinum,
silver
* Reference Electrode: pH - Ag/AgCl combination
* Auto ranging facility
Software for system control, data acquisition, data processing and
reporting
Suitable PC & Printer and Nitrogen gas cylinder are to be quoted.
UV-Visible detector with suitable PEEK Ion-Exchange columns
for analyzing Transition Metals / Heavy Metals Cu, Co, Cd, Ni,
Mn, Pb, Zn and speciation.
(a) UV-Visible Detector with PEEK cell.
Optical System : Dual beam optic design Monochromator
Wavelength Range
: 190-900 nm in 1 nm increments
Wavelength Accuracy
: ± 1 nm
Bandwidth
: 6 nm
Noise
: Typically <±2.5 mAU at 254 nm
Drift
: < 0.1 mAU/h
Cell Path Length
: 10 mm
Cell Volume
: 10 or more µL
HPLC
Chromatography
b) Two sets of columns for anions/cations as well as reverse phase
for analyzing trace elements, heavy metals and their speciation.
System should have the capability to connect with ICP-MS for
metal speciation studies
The HPLC System shall include the following individual stackable
self-contained HPLC modules
Quaternary solvent delivery system
 Flow rate - 0.001 to 5 ml/min, with ± 0.5% or ± 1ul/min
accuracy and precision of less than ± 0.075% RSD,
 Maximum pressure setting range should be 15000 psi or more
 Leak sensor should be included as safety feature and
maintenance kit with reservoir tray (with 4 solvent bottles
complete with fittings) should be included
Degassing unit: On line membrane degassing unit with maximum
operating flow rate up to 10ml/min or more per flow line
Diode Array Detector:
 Photodiodes: 512 diodes or more
 Light source: Deuterium and Tungsten
 Wavelength range : 190 nm to 800 nmwith accuracy ± 1 nm
and reproducibility ± 1 nm
 The flow cell must be temperature controlled from ambient +5
0
C to 40 0C
Manual injector kit
Manual injector kit with S-S manual injector valve and Rheodyne
7725 injector
Auto sampler injector
 Sample injection system with variable injection volume
between 0.1µL to 50µL and zero sample loss during injection
 Flow line rinse capability both before and after sampling with
less than 0.005% carry over
 Should have safety features like automatic rack and vial
recognition and leak sensor
System software
 System software must be compatible with wireless networking
and controllable from a web based interface via net work
 Expert function with automatic purging of mobile phase if
pressure falls below specified value
 Should be able to store minimum of 20 analysis files
Columns
 C 18 Column 150mm*2.1mm*3.1u- with guard column – 1 No
Sonicator
Sample & Solvent
Filtration Kit with
suitable Vacuum
Pump
Accelerated
Solvent Extractor
for Sample
Preparation
 C8 Column 150mm*2.1mm*3.1u- with guard column – 1 No
 C 18 Column 250mm*4.6mm*5u- with guard column – 1 No
 C 8 Column 250mm*4.6mm*5u- with guard column – 1 No
Data Management system
 Hard ware
o Intel core i5 Duo processor with 2GB RAM or higher and
500GB hard disk or higher with pre-installed Windows 10
Software
o Operation of the system should be easy and intuitive
o Security features of software must be comply fully with FDA
21 CFR Part 11
o It should cover full digital instrument control with qualitative
and quantitative processing, report creation, self-diagnosis and
auto- tuning
o Should have the ability for simultaneous monitoring and
quantitation of 8 different wave lengths
o Provision of online help function for users
 5 L capacity with heating facility

It should include oven, pump, fluid sensors, collection bottles
and Display & key board
SPECIFICATION FOR REAL TIME PCR
Sl.No. Real Time PCR, point 11:
LED Excitation Source with Photodiode / Photo Multiplier Tube as Detection Source or better
Sl.No. 10: Power Supply for Vertical / horizontal and Blotting Apparatus, point 13
Warranty 3 years
Sl. No. 11: Consumables for RT PCR
Required Reagents/consumables for continuous operation of equipment: 2 sets