PHG 531 “Structure Elucidation of Natural Products

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Post Graduate Cources:
I-Master Degree Cources:
PHG 523 “Selected Topics in Natural Products Chemistry” (2+0)
This course is intended to provide the student with up-to-date knowledge of
various areas of growing interest within natural products and medicinal plant research.
Examples are:
1-Naturally occurring estrogenic compounds
2-Plant allergens and teratogens
3-Plant toxicants and their medicinal us
PHG 531 “Structure Elucidation of Natural Products-I” (3+0)
This course is intended to provide the student with expertise in the various
methods used for the structure elucidation of natural products. He should be able to
utilize various spectral data, including IR, UV, H-NMR, C-NMR and MS for the
structure elucidation of selected compounds, belonging to diverse structure types. In
addition, he should be able to utilize degradative and synthetic reactions for structure
elucidation or confirmation of the proposed structure.
PHG 540 “Biosynthesis of medicinal plants constituents” (3+0)
This course is intended to provide the student with a thorough knowledge of the various
biosynthetic pathways of medicinal plants constituents.It also deals with the techniques
for elucidation of biosynthetic pathways.In addition, the course covers the use of
recombinant DNA technology for the synthesis of natural products.The role of
chemotaxonomy and biochemical systematics in plant classification will be also pointed
out.
II-Cources for Doctor of Philosophy Degree:
PHG 610:”Selected research Topics in Pharmacognosy”(0+2):
The goal of the course is to prepare the student to work on the practical part of the theses
The course deals with a research project or more ,coserned with isolation or biosynthesis
or biotransformation , in the field of medicinal plants.
The student must provide a report at mid of the term as well as a final report about the
collected results.
The project under my supervision is
Isolation and structure elucidation of Erythrina lysistemon alkaloids
PHG 614 “Seminar “:
The Seminar ,under my supervision is An Overview of Caesalpinioideae Family
Leguminosae.
Under Graduate Cources:
PHG 251 “Pharmacognosy-1” (2+1):
The course comprises two main parts; the first one is an introduction to pharmacognosy
covering drugs of natural origin. This includes their sources, bioactive constituents,and
preparation for pharmaceutical use
The second part of the course covers chromatographic principles and methodology
including planar(PC,TLC and related techniques such as electrophoresis) and
columnar(GC, HPLC, IEC,GPC)chromatography as well as their application in drug
evaluation.
PHG 351 “Pharmacognosy-1I” (2+1):
The course deals with the chemistry of crude drugs phytochemistry. Emphasis will be
given to the study of bioactive constituents such as carbohydrates, glycosides and
alkaloids.The study deals with their isolation,identification,structure activity relationship
(SAR),medicinal uses and determination of these constituents, using chromatographic
and spectroscopic methods.
PHG 456 “Evaluation of vegetable and animal drugs”:
The course deals with the different criteria used for the evaluation of drugs of animal and
vegetable origin.The study which will cover the drugs both in the crude form and in the
form of pharmaceutical preparations. It will include methods to test their physical and
microscopic properties,constituents and cotaminants ,including filth,herbicides and any
additives.The current regulations of the Ministry of Health ,concerning these drugs will
will be discussed as they pertain to each item .
PHG 461 “Pharmacognosy-4”:
The course deals with the study of antibiotics, naturally occurring antineoplastic agents.
Members of different classes of antibiotics will be covered with respect to their
origin,chemistry, structure-activity relationship,mechanism of action,antimicrobial
spectrum,toxicity,clinical indications and contraindications and assay procedures.
The study of antineoplastic agents will be preceded by a brief introduction about
carcinogenic and cancer-preventing agents,followed by an in depth study of the
individual anticancer agents.
Cemistry an dindication of clinically available eicosanoids will be studied.
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