NAME
BIOGRAPHICAL SKETCH
Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2.
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Andras Fiser
POSITION TITLE
Assistant Professor of Biochemistry
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
DEGREE
(if applicable)
YEAR(s) FIELD OF STUDY
Eotvos Lorand University, Budapest, Hungary
Institute of Enzymology, Budapest, Hungary
The Rockefeller University, New York, N.Y.
M. Sc.
Ph.D.
Postdoc
1986-91 Chemistry
1991-97 Biophysics
1997-02 Mol. Biophysics
Positions and Employment
1991-92 Junior research fellow at the Institute of Enzymology, Hungarian Academy of Sciences
1992-96 Scholar of the Scientific Qualificatory Committee of the Hungarian Academy of Sciences
1993-94 Visiting student at the Laboratory of Molecular Biophysics and member of New College,
University of Oxford, UK.
1996-97 Research fellow at the Institute of Enzymology, Hungary, Protein Structure Research Group
1997-02 Postdoctoral fellow at The Rockefeller University, Laboratories of Molecular Biophysics
2003- Assistant Professor, Department of Biochemistry, Albert Einstein College of Medicine
Honors
1993-94
1992-96
Soros Fellowship in Oxford University (UK)
Scholar of the Scientific Qualificatory Committee, Hungarian Academy of Sciences (Hungary)
1997-2001 Burroughs Wellcome Trust Fellow, Rockefeller University (USA)
2001-2002 Charles Revson Fellowship, Rockefeller University (USA)
Fiser, A., Tusnady, G.E. and Simon, I. Chaos Game Representation of Protein Structures .
J. Mol. Graphics (1994) 12, 302-304
Fiser, A., Dosztanyi, Zs. and Simon, I. The role of long range interactions in defining the secondary structures in proteins is overestimated
Comp. Appl. Biosci. (1996) 13, 297-301
Dosztanyi, Zs., Fiser, A. and Simon, I. Stabilisation centers in proteins: identification, characterization and prediction
J. Mol. Biol. (1997) 272, 597-612
Wu, G, Fiser, A., ter Kuile B, Sali, A. and Muller M. Convergent evolution of Trichomonas vaginalis lactate dehydrogenase from malate dehydrogenase
Proc Natl Acad Sci USA 1999 May 25;96(11):6285-6290
Marti-Renom, M.A., Stuart, A., Fiser, A., Sanchez, R., Melo, F. and Sali, A. Comparative protein structure modeling of genes and genomes
Ann. Rev. Biophys. Biomolec. Struct., (2000) 29, 291-325
Fiser, A. and Simon, I. Predicting the redox state of cysteins in proteins from multiple sequence alignments
Bioinformatics (2000) 16, 251-256
Wu, G., Morrison, H.G., Fiser, A., McArthur, A.G., Sali, A., Sogin, M.L. and Muller, M.. Core histones of the amitochondriate protist, Giardia lamblia.
PHS 398/2590 (Rev. 09/04) Page Biographical Sketch Format Page

Mol. Biol. Evol. (2000) 17, 1156-1163
Fiser, A., Do, R.K.G. and Sali, A. Modeling of loops in protein structures
Prot. Sci. (2000) 9,1753-1773
Barrientos, L.G., Campos-Olivas, R., Louis, J.M. Fiser, A., Sali, A., Gronenborn, A.M. H, C, N Resonance assignments and fold verification of a circular permuted variant of the potent HIV-inactivating
Protein Cyanovirin-N
J. Biomol. NMR, (2001) 19, 289-290
Eyrich, V., Marti-Renom, M.A., Przybylski, D., Fiser, A., Pazos, A., Valencia, A., Sali A., and Rost, B. EVA: continuous automatic evaluation of protein structure prediction servers
Bioinformatics (2001) 17, 1242-1243
Fiser, A. and Sali, A. Evolution and phyics in comparative protein structure modeling
Acc. Chem Res. (2002) 35:413-21
Marti-Renom, M.A., Madhusudan, M.S., Fiser, A., Rost, B., and Sali, A. Reliability of assessment of protein structure prediction methods at CASP
Structure with Folding and Design (2002) 10, 435-440
Fiser, A. and Sali, A. MODELLER: Calculating and refining homology models
Methods Enzymol. (2003) 374, 461-491
Chance MR, Fiser A, Sali A, Pieper U, Eswar N, Xu G, Fajardo JE, Radhakannan T, Marinkovic N. High- throughput computational and experimental techniques in structural genomics.
Genome Res . (2004) 14, 2145-54.
Fiser A. Protein structure modeling in the proteomics era.
Expert Rev Proteomics.
(2004) 1:97-110.
Bonanno JB, Almo SC, Bresnick A, Chance MR, Fiser A, Swaminathan S, Jiang J, Studier FW, Shapiro L,
Lima CD, Gaasterland TM, Sali A, Bain K, Feil I, Gao X, Lorimer D, Ramos A, Sauder JM,
Wasserman SR, Emtage S, D'Amico KL, Burley SK. New York-Structural GenomiX Research
Consortium (NYSGXRC): A Large Scale Center for the Protein Structure Initiative.
J Struct Funct Genomics.
(2005) 6:225-32.
Vetting MW, Hegde SS, Fajardo JE, Fiser A, Roderick SL, Takiff HE, Blanchard JS Pentapeptide Repeat
Proteins.
Biochemistry.
2006 Jan 10;45(1):1-10
Reichman C, Singh K, Liu Y, Singh S, Li H, Fajardo JE, Fiser A, Birge RB. Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.
Oncogene.
2005 Dec 8;24(55):8187-99
Rai BK, Fiser A. Multiple mapping method: a novel approach to the sequence-to-structure alignment problem in comparative protein structure modeling
Proteins, Structure, Function and Bioinformatics (2006) 63:644-61
Fernandez-Fuentes N, Oliva B, Fiser A. A supersecondary structure library and search algorithm for modeling loops in protein structures
Nucleic Acids Res .
(2006) 34:2085-97
Xiao H, Vedier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA. Insights into the mechanism of microtubule stabilization by Taxol
Proc. Natl. Acad. Sci. USA (2006) 103:10166-73
Fernandez-Fuentes N and Fiser A. Saturating representation of loop conformational fragments in structure databanks
BMC Structural Biol.
. (2006) 6:15
Fernandez-Fuentes N, Zhai J, and Fiser A. ArchPRED: a template based loop structure prediction server
Nucleic Acids Res.
(2006) 34:w173-6
Rai BK, Madrid-Aliste CJ, Fajardo JE andFiser A. MMM: a sequence-to-structure alignment protocol
Bioinformatics . (2006) 22, 2691-2
Chattopadhyay K, Bhatia S, Fiser A, Almo SC and Nathenson SG. Structural basis of inducible costimulator ligand costimulatory function: determination of the cell surface oligomeric state and functional mapping of the receptor binding site of the protein .
J Immunol.
(2006) 177(6):3920-9
PHS 398/2590 (Rev. 09/04) Page Continuation Format Page